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腹腔镜解剖性半肝切除中肝蒂处理与吲哚菁绿剂量影响荧光染色效果的研究

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外科理论与实践 2024年第2期29卷 138-142页

作者：路志宇孙骥杜加录蒙轩罗漫刘玥王宏光国家癌症中心国家肿瘤临床医学研究中心中国医学科学院肿瘤医院廊坊院区肝胆外科河北廊坊065001 国家癌症中心国家肿瘤临床医学研究中心中国医学科学院肿瘤医院肝胆外科北京100021 陕西省榆林市第一医院肝胆外科陕西榆林719000

目的:探讨腹腔镜解剖性半肝切除术中吲哚菁绿(ICG)荧光染色的方法及剂量选择。方法:采用回顾性横断面研究方法。收集分析2020年10月至2023年10月中国医学科学院肿瘤医院完成的腹腔镜解剖性半肝切除术病人的临床资料,分析肝蒂处理方式、... 详细信息

目的:探讨腹腔镜解剖性半肝切除术中吲哚菁绿(ICG)荧光染色的方法及剂量选择。方法:采用回顾性横断面研究方法。收集分析2020年10月至2023年10月中国医学科学院肿瘤医院完成的腹腔镜解剖性半肝切除术病人的临床资料,分析肝蒂处理方式、术中ICG荧光染色的方法及效果、ICG注射剂量、术后恢复情况等。结果:共完成腹腔镜解剖性半肝切除术91例,右半肝切除28例,左半肝切除63例。肝蒂处理采用鞘内解剖9例,鞘外解剖82例。ICG荧光染色均采用反染法,其中69例(75.8%)染色成功。肝蒂鞘外解剖、ICG低剂量组较鞘内解剖、ICG高剂量组的染色成功率高。平均手术时间(168.5±32.2)min,术中出血量(152.4±56.3)mL,术中输血6例(6.6%),平均术后住院时间(8.5±2.6)d。中转开腹1例,原因为肿瘤外生性生长压迫肝蒂。4例发生Clavien-DindoⅠ~Ⅱ级并发症,均经治疗后好转。Ⅲa级并发症3例,均为胆漏引起腹腔感染,经穿刺引流治愈。无Ⅲb级以上严重并发症。结论:腹腔镜解剖性半肝切除术ICG荧光染色方法推荐Glisson蒂鞘外解剖的反染法,较低的ICG剂量有助于提高荧光染色成功率。

关键词：腹腔镜半肝切除吲哚菁绿

Compact Harris Hawks Optimization Algorithm

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Compact Harris Hawks Optimization Algorithm

第40届中国控制会议

作者： Zhihao Yu jialu du Guangqiang Li School of Marine Electrical Engineering Dalian Maritime University

The intelligent optimization algorithm performs well in solving complex optimization problems in engineering. However, the intelligent optimization algorithm usually takes long execution time and large memory usage, which is not suitable for the engineering with limited hardware conditions. To handle this difficulty, in this paper, a novel compact harris hawks optimization（cHHO） algorithm is proposed, which is an modified version of the harris hawks optimization（HHO） algorithm. The cHHO algorithm searches the optimal solution using only one hawk, instead of a whole swarm of hawks in the HHO algorithm,by means of the compact optimization theory. Numerical experiments based on two commonly used benchmark functions show that the execution time of the cHHO algorithm is shorter and the memory usage is smaller, comparing with the HHO algorithm and the compact particle swarm optimization algorithm. Further, the c HHO algorithm is employed to the thrust allocation of a dynamic positioning vessel, and the simulation illustrates the effectiveness of the cHHO algorithm.

关键词： Harris Hawks Optimization Algorithm Compact Optimization Thrust Allocation

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高性能水基钻井液体系设计原理及应用

当代化工 2024年第6期53卷 1431-1434页

作者：曾立祥章洋阳田夏荷杜佳璐南宇宋明明李雨晴吕涛西安长庆化工集团有限公司陕西西安710018 西安石油大学陕西西安710065

为解决油基钻井液带来的环保压力与经济成本的上升,新型水基钻井液的研究与推广势在必行。通过XRD和环境扫描电子显微镜的实验方法分析页岩气储层地质特征,同时以钻井液在岩心封堵实验、滚动回收率和润滑性测试方法评价该水基钻井液的... 详细信息

为解决油基钻井液带来的环保压力与经济成本的上升,新型水基钻井液的研究与推广势在必行。通过XRD和环境扫描电子显微镜的实验方法分析页岩气储层地质特征,同时以钻井液在岩心封堵实验、滚动回收率和润滑性测试方法评价该水基钻井液的封堵性、抑制性和润滑性等关键性能。结果表明,该水基钻井液体系高温高压滤失量小于6 mL,岩心封堵效率达83.52%,体系对红层土和龙马溪组页岩露头(某区域)的岩样滚动回收率均在95%以上,说明该体系流变及滤失造壁性稳定,具有强封堵和抑制能力;钻井液体系摩阻系数为0.0804,所形成滤饼的黏滞系数为0.0753,钻井液体系润滑能力较好:在100~160℃时钻井液体系均保持相对稳定的流变性及滤失造壁性,抗温性良好。该体系具备良好的封堵与抑制能力,接近油基钻井液效果,可节约钻井成本,具有广阔的应用前景。

关键词：页岩气井壁稳定水基钻井液体系体系评价应用前景

Command Filter Backstepping based Trajectory Tracking Control of Underactuated Surface Vessels

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Command Filter Backstepping based Trajectory Tracking Contro...

第40届中国控制会议

作者： Ziping Wei jialu du Cong Tan Jian Li School of Marine Electrical Engineering Dalian Maritime University

This paper focuses on the trajectory tracking control problem for underactuated surface vessels with ocean environment disturbances. To overcome difficulty caused by the underactuation, an output redefinition method is adopted to redefine the vessel position outputs. An adaptive law is designed to estimate the upper bounds of the ocean environment disturbances. On the basis of the above, a trajectory tracking control law using the command filtered backstepping control method is proposed and the "differential explosion" problem could be avoided comparing with the conventional backstepping method. Theoretical analysis and simulation results show that the proposed control law can force the underactuated surface vessels to track the desired trajectory, while all signals in the trajectory tracking closed-loop control system are proved to be uniformly ultimately bounded.

关键词： Trajectory tracking Underactuated surface vessels Command filtered backstepping Output redefinition

Data-Mining-Based Fuzzy Control Design for Marine Dynamic Positioning System of Ships

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Data-Mining-Based Fuzzy Control Design for Marine Dynamic Po...

第37届中国控制会议

作者： Xin Hu jialu du Jian Li Chuansheng Yang School of Marine Electrical Engineering Dalian Maritime University School of Mathematics Physicsand Information ScienceZhejiang Ocean University

Considering the dynamic positioning（DP） problem of a surface ship with unknown model dynamic parameters and unknown environmental disturbances,this paper develops a data-mining-based fuzzy control *** the certain operating and environmental conditions of a ship,the scientific and effective fuzzy rules for the DP of ships are extracted using the data-mining *** on the extracted fuzzy rules,the DP fuzzy control law is ***,the simulation studies on a supply ship Northern Clipper are carried out to verify the effectiveness of the designed DP fuzzy control law.

关键词： Dynamic positioning of ships unknown model parameters unknown disturbances data-mining fuzzy control

Synergistic Effects of Bay of Bengal Tropical Cyclones and Tibetan Plateau Vortices on Water Vapor Transport over the Tibetan Plateau in Early Summer

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Journal of Meteorological Research 2024年第2期38卷 383-398页

作者： jialu LIN Ying LI Beiyao LIU Pengchao AN State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesChina Meteorological AdministrationBeijing 100081 University of Chinese Academy of Sciences Beijing 100049 Department of Atmospheric and Oceanic Sciences and Institute of Atmospheric Sciences Fudan UniversityShanghai 200433

The Bay of Bengal(BoB)tropical cyclones(TCs)and the Tibetan Plateau vortices(TPVs)are two crucial weather systems influencing the Tibetan Plateau(TP).Their synergistic effects can lead to widespread heavy precipitation events on the *** this study,we employ the Hybrid Single-Particle Lagrangian Integrated Trajectory(HYSPLIT)model to track the trajectory of water vapor transport during three large-scale precipitation events on the TP under the combined influence of BoB TCs and *** results indicate that low-level water vapor from the BoB under the influence of BoB TCs was cyclonically entangled into the cyclonic circulation,lifted and transported northward by southwesterly flow to the southeastern part of the TP,which contributes to the moistening of the entire troposphere ***,convergence of the cyclonic circulation of the TPVs on the northern TP further transports water vapor collected in the southeastern TP northward,conducive to the maintenance and development of precipitation systems,thus inducing widespread heavy precipitation events over the TP.

关键词： Bay of Bengal(BoB) tropical cyclones(TCs) Tibetan Plateau vortices(TPVs) trajectory tracing water vapor transport

Identifying Comprehensive Genomic Alterations and Potential Neoantigens for Cervical Cancer Immunotherapy in a Cohort of Chinese Squamous Cell Carcinoma of the Cervix

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Biomedical and Environmental Sciences 2024年第6期37卷 565-580页

作者： Meng Wu jialu Zhou Zhe Zhang Yuanguang Meng School of Medicine Nankai UniversityTianjin 300071China Department of Obstetrics and Gynecology The First Medical Center of Chinese PLA General HospitalBeijing 100853China Department of Obstetrics and Gynecology Chinese PLA Medical SchoolBeijing 100853China Department of Obstetrics and Gynecology The Seventh Medical Center of Chinese PLA General HospitalBeijing 100700China

Objective Genomic alterations and potential neoantigens for cervical cancer immunotherapy were identified in a cohort of Chinese patients with cervical squamous cell carcinoma(CSCC).Methods Whole-exome sequencing was used to identify genomic alterations and potential neoantigens for CSCC *** Sequencing was performed to analyze neoantigen *** Systematic bioinformatics analysis showed that C>T/G>A transitions/transversions were dominant in *** mutations were the most frequent types of somatic mutation in the coding sequence *** signature analysis detected signature 2,signature 6,and signature 7 in CSCC ***3CA,FBXW7,and BICRA were identified as potential driver genes,with BICRA as a newly reported *** variation profiling identified 4,960 potential neoantigens,of which 114 were listed in two neoantigen-related *** The present findings contribute to our understanding of the genomic characteristics of CSCC and provide a foundation for the development of new biotechnology methods for individualized immunotherapy in CSCC.

关键词： Cervical squamous cell carcinoma Genome alteration Neoantigens Immunotherapy

Design,preparation,and characterization of a novel ZnO/CuO/Al energetic diode with dual functionality:Logic and destruction

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Defence Technology（防务技术） 2024年第4期34卷 57-68页

作者： jialu Yang Jiaheng Hu Yinghua Ye Jianbing Xu Yan Hu Ruiqi Shen School of Chemistry and Chemical Engineering Nanjing University of Science and TechnologyNanjing 210094China Micro-Nano Energetic Devices Key Laboratory of MIIT Nanjing 210094China Institute of Space Propulsion Nanjing University of Science and TechnologyNanjing 210094China

Self-destructing chips have promising applications for securing *** paper proposes a new concept of energetic diodes for the first time,which can be used for self-destructive chips.A simple two-step electrochemical deposition method is used to prepare ZnO/CuO/Al energetic diode,in which N-type ZnO and P-type CuO are constricted to a PN *** paper comprehensively discusses the material properties,morphology,semiconductor characteristics,and exploding performances of the energetic *** results show that the energetic diode has typical rectification with a turn-on voltage of about 1.78 V and a reverse leakage current of about 3×10^(-4)*** a constant voltage of 70 V loads to the energetic diode in the forward direction for about 0.14 s or 55 V loads in the reverse direction for about 0.17 s,the loaded power can excite the energetic diode exploding and the current rises to about100 *** to the unique performance of the energetic diode,it has a double function of rectification and *** energetic diode can be used as a logic element in the normal chip to complete the regular operation,and it can release energy to destroy the chip accurately.

关键词： Energetic diode ZnO—CuO—Al thermite ZnO/CuO PN junction Electrical explosion performance Self-destructing chips

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航行补给中的补给船鲁棒同步控制

华中科技大学学报（自然科学版） 2018年第2期46卷 61-66页

作者：胡鑫刘永超杜佳璐大连海事大学船舶电气工程学院

针对航行补给作业的补给船同步航行控制问题,考虑了补给船动态不确定性和未知时变环境扰动,将扰动观测器和矢量逆推方法相结合,设计了补给船鲁棒同步航行控制律.在被补给船的某一舷外引入与其航迹距离相对固定的虚拟航迹,构造扰动观测器... 详细信息

针对航行补给作业的补给船同步航行控制问题,考虑了补给船动态不确定性和未知时变环境扰动,将扰动观测器和矢量逆推方法相结合,设计了补给船鲁棒同步航行控制律.在被补给船的某一舷外引入与其航迹距离相对固定的虚拟航迹,构造扰动观测器,估计由船舶动态不确定性和时变扰动构成的复合扰动;采用矢量逆推方法,设计补给船鲁棒同步航行控制律,使补给船能够以任意小的误差跟踪虚拟航迹,从而实现补给船与被补给船的同步航行,并保证补给船航迹闭环控制系统中所有信号全局一致最终有界.基于一艘补给船的仿真研究结果及比较验证了所提出的补给船同步航行控制律的有效性和低保守性.

关键词：船舶航行补给鲁棒同步控制虚拟航迹扰动观测器矢量逆推