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实习护士经皮水分丢失和手部皮炎的发病率:一组前瞻性随访

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世界核心医学期刊文摘（皮肤病学分册） 2005年第9期1卷 40-40页

作者： Sch.id K. Broding h.C. Uter W. drexler h. 王琼 Institute and Outpatient Clinic for Occupational Social and Environmental Medicine University Erlangen-Nuremberg Schillerstru.e 25 29 D-91054 Erlangen Germany Dr.

Th. purpose of th. study was to evaluate th. incidence of h.nd dermatitis, th. impact of potential risk factors and th. efficacy of skin bioengineering in a prospectively followed coh.rt of apprentice nurses. 104 participants were prospectively followed for 3 years. Before th. start of training, after about 1 year and in th. th.rd year of occupational exposure, a standardized questionnaire was distributed, and a clinical examination with.skin bioengineering of th. dorsum of h.nd and forearm was performed. Th. 12-month.period prevalence of self-reported symptoms of h.nd dermatitis was 36.5% 95%-confidence interval (CI) 27.3-46.6 at intermediate follow-up and 43.3%(95%-CI 33.6-53.3) at th. final examination. Apprentices with.self-reported symptoms at th. final examination sh.wed a significant increase of transepidermal water loss (TEWL) at th. dorsal h.nd from 10.15 g/ m2h.to 13.55 g/m2h. TEWL at th.s site did, at th. initial examination, not differ significantly be-tween persons wh. later reported symptoms of h.nd dermatitis at th. final examination and th.se wh. did not (10.50 g/m 2h.versus 10.15 g/m2h. respectively). Our results do not support th. notion th.t an increased basal TEWL is a good indicator for h.nd dermatitis risk.

关键词：实习护士生物工程学职业性暴露初始检查前臂皮肤潜在危险因素自我报告无症状炎症状

MRI Newsletter 6: Global Ch.nge Research.in Mountain Biosph.re Reserves of th. Russian Federation

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Journal of Mountain Science 2006年第2期3卷 178-180页

作者： Yuri Badenkov Claudia drexler Leader of th. Mountain Group Institute of Geography Russian Academy of Sciences Staromonetny 29 119017 Moscow Russia. Communication and Event Management The Mountain Research Initiative (MRI) Schwarztorstrasse 9 3007 Berne Switzerland.

Global ch.nge research.in Russia＇s protected areas Mountains and h.gh.ands occupy more th.n 50 % of th. territory of th. Russian Federation. In 2005, Russia h.d 36 Biosph.re Reserves （BRs）, of wh.ch.15 are Mountain Biosph.re Reserves （MBRs）. Th. MBRs represent different environmental and economic zones of North.rn Eurasia; th.y lie far apart from one anoth.r （Figure 1）. Laplandskiy MBR on th. Kola Peninsula （No 1） is an example of a reserve located in th. arctic belt and affected by th. mining industry, wh.le Kavkazskiy MBR （No 2）, 25oo km furth.r south.and located on th. border with.Georgia, represents eastern Mediterranean ecoregional features.

关键词：山脉生态圈全球变化俄罗斯

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慢性心功能不全时外周循环的变化

德国医学 1994年第2期11卷 63-64页

作者： h.drexler 王来 Medizinisch. Universittsklinik Ⅲ FreiburgGermany 同济医科大学附属医院

心肌梗塞或高血压所致慢性压力负荷和容量负荷增加,首先通过心脏和外周循环调节机制维持适当的心排出量和外周器官灌注,进而发生心脏和外周循环功能及结构上的变化,影响心功能不全的发生和预后。心脏大小和质的变化影响心功能不全早期... 详细信息

心肌梗塞或高血压所致慢性压力负荷和容量负荷增加,首先通过心脏和外周循环调节机制维持适当的心排出量和外周器官灌注,进而发生心脏和外周循环功能及结构上的变化,影响心功能不全的发生和预后。心脏大小和质的变化影响心功能不全早期死亡率和恶化,外周循环的调节则在一定程度上决定心功能不全后期的临床表现和进展变化。因此,识别调节机制对治疗具有重要意义。

关键词：心脏功能不全外周循环血管变化

Toward optical coh.rence tomograph. on a ch.p: in vivo th.ee-dimensional h.man retinal imaging using ph.tonic integrated circuit-based arrayed waveguide gratings

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Ligh.(Science & Applications) 2021年第1期10卷 71-85页

作者： Elisabet A.Rank Ryan Sentosa Danielle J.h.rper Matth.as Salas Anna Gaugutz Dana Seyringer Stefan Nevlacsil Alejandro Maese-Novo Moritz Eggeling Paul Muellner Rainer h.inberger Martin Sagmeister Joch.n Kraft Rainer ALeitgeb Wolfgang drexler Center for Medical Ph.sics and Biomedical Engineering Medical University of ViennaWaehringer Guertel 18-20/4 L1090 ViennaAustria Research.Centre for Microtech.ology Vorarlberg University of Applied SciencesHochschulstrasse 16850 DornbirnAustria AIT Austrian Institute of Tech.ology Gmbh Gieffinggasse 41210 ViennaAustria ams AG Tobelbader Strasse 308141 PremstaettenAustria

In th.s work,we present a significant step toward in vivo oph.h.lmic optical coh.rence tomograph. and angiograph. on a ph.tonic integrated *** diffraction gratings used in spectral-domain optical coh.rence tomograph. can be replaced by ph.tonic integrated circuits comprising an arrayed waveguide *** arrayed waveguide grating designs with.256 ch.nnels were tested,wh.ch.enabled th. first ch.p-based optical coh.rence tomograph. and angiograph. in vivo th.ee-dimensional h.man retinal *** 1 supports a bandwidth.of 22nm,with.wh.ch.a sensitivity of up to 91 dB(830μW) and an axial resolution of 10.7 pm was *** 2 supports a bandwidth.of 48 nm,with.wh.ch.a sensitivity of 90 dB(480μW) and an axial resolution of 6.5μm was *** silicon nitride-based integrated optical waveguides were fabricated with.a fully CMOS-compatible process,wh.ch.allows th.ir monolith.c co-integration on top of an optoelectronic silicon *** a bench.ark for ch.p-based optical coh.rence tomograph.,tomograms generated by a commercially available clinical spectral-domain optical coh.rence tomograph. system were compared to th.se acquired with.on-ch.p *** similarities in th. tomograms demonstrate th. significant clinical potential for furth.r integration of optical coh.rence tomograph. on a ch.p system.

关键词： waveguide arrayed optical

Modified Vaccinia Virus Ankara Induces Autoph.gy to Enh.nce Endogenous Mh. ⅡAntigen Processing Path.ays in Dendritic Cells

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Modified Vaccinia Virus Ankara Induces Autophagy to Enhance ...

中华医学会2014全国微生物学与免疫学学术年会

作者：张懿 Frank Th.ele Ingo drexler 德国慕尼黑工业大学病毒所重庆医科大学感染性疾病分子生物学教育部重点实验室德国杜塞尔多夫大学分子病毒所

Modified vaccinia virus Ankara(MVA)is non-permissive in h.man cells due to a blockage of viral replication occurs at th. late stage of virion *** is considered as a prospective vaccine candidate for immunoth.rapy because of h.gh.safety record and strong ***,an intracellular bulk system,can engulf cytoplasmic path.gens and deliver th.m to lysosomes for lysis or engergy recycling,so th.t subsequently facilitates antigen ***

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慢性心功能不全的病理生理学

德国医学 2001年第1期18卷 11-16页

作者： M.Fuch. h.drexler 高亚东 AbteilungKardiologie und Angiologie Medizinische Hochschule Hannover 华中科技大学同济医学院附属同济医院

定　义　　心功能不全是指心脏不能为组织的代谢和循环提供足够的血液，或只有在充盈压异常增高时才能完成其功能。　　心功能不全的特征是导致发生局部和全身的适应机制。这一机制首先是代偿下降的心功能，以保证器官的灌流量。心脏和... 详细信息

定　义　　心功能不全是指心脏不能为组织的代谢和循环提供足够的血液，或只有在充盈压异常增高时才能完成其功能。　　心功能不全的特征是导致发生局部和全身的适应机制。这一机制首先是代偿下降的心功能，以保证器官的灌流量。心脏和循环系统代偿的长期结果是功能和结构的改变，并使慢性心功能不全进行性加重。后期才常出现的或早期仅在负荷状态下才出现的症状，是代偿机制业已启动的表现。　　慢性心功能不全以前被看成心-肾问题及与之相关的水钠潴留，并因而成为利尿治疗的理由。后来在更好地理解收缩期紧张与舒张期松弛的基础上，注意到了泵功能下降在阐明慢性心功能不全发病机理时的重要作用。全身血管收缩也是循环功能不全的重要致病因素。这一心脏循环模式已用于药物治疗，其目的在于增加心肌收缩力和扩张血管。　　过去10年内一些实验和临床研究表明，慢性心功能不全的特征是神经体液激活，特别是交感神经系统和肾素-血管紧张素-醛固酮系统的激活。因而，使用转换酶抑制剂和血管紧张素受体拮抗剂抑制肾素-血管紧张素-醛固酮系统，用β-阻滞剂阻断交感张力，可延缓心功能不全的进程或发展。最新研究结果表明，心功能不全过程中可出现前炎性细胞因子的激活，因而炎症因素可能在心功能不全的功能和结构改变中发挥作用，使慢性心功能不全加重。

关键词：慢性心功能不全病理生理学病因

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X射线诊断中的职业照射

国外医学（放射医学核医学分册） 1991年第5期15卷 205-206页

作者： drexler G Panzer W 戴光复

个人剂量的常规监测和现场的常规测量结果表明,职业性的全身剂量一般是很低的,而局部体剂量特别是手部和手指剂量可能达到剂量限值.因此,需要对局部体剂量进行监测.

关键词： X线诊断职业照射剂量监测

心肌梗死后冠状动脉内自体骨髓细胞输注:BOOST随机对照临床试验

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世界核心医学期刊文摘（心脏病学分册） 2005年第1期1卷 9-10页

作者： Wollert K.C. Meyer G.P. Lotz J. h. drexler 高峰 Abteilung Kardiologi e und Angiologie Medizinische Hochschule Hannover Carl-Neuberg Strasse 1 30625 Hannover GermanyProf.

Background Emerging evidence suggests th.t stem cells and progenitor ce lls der ived from bone marrow can be used to improve cardiac function in patients after acute myocardial infarction. In th.s randomised trial, we aimed to assess wh.th. r intracoronary transfer of autologous bone-marrow cells could improve global l eft-ventricular ejection fraction (LVEF) at 6 month.’follow-up. Meth.ds After successful percutaneous coronary intervention (PCI) for acute ST-segment eleva tion myocardial infarction, 60 patients were randomly assigned to eith.r a contr ol group (n=30) th.t received optimum postinfarction medical treatment, or a bon e-marrow-cell group (n=30) th.t received optimum medical treatment and intraco ronary transfer of autologous bone-marrow cells 4.8 days (SD 1.3) after PCI. Pr imary endpoint was global left-ventricular ejection fraction (LVEF) ch.nge from baseline to 6 month.’follow-up, as determined by cardiac MRI. Image analyses were done by two investigators blinded for treatment assignment. Analysis was pe r protocol. Findings Global LVEF at baseline (determined 3.5 days > after PCI) was 51.3 (9.3%) in controls and 50.0(10.0%) in th. bone-marrow cell group (p=0.59). After 6 month., mean global LVEF h.d increased by 0.7 percentage points in th. c ontrol group and 6.7 percentage points in th. bone-marrow-cell group (p=0.0026 ). Transfer of bone-marrow cells enh.nced left-ventricular systolic function p rimarily in myocardial segments adjacent to th. infarcted area. Cell transfer di d not increase th. risk of adverse clinical events, in-stent restenosis, or pro arrh.th.ic effects. Interpretation Intracoronary transfer of autologous bone-ma rrow-cells promotes improvement of left-ventricular systolic function in patie nts after acute myocardial infarction.

关键词： BOOST 自体骨髓细胞输注心脏功能支架内再狭窄收缩功能梗死区心肌节段药物治疗射血分数

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如何把握拥抱礼仪的分寸?（英文）

大学英语 2014年第6期 38-40页

作者： Peggy drexler 路遥

I’m not a *** I see a registered personal-space invader coming my way at a party,th. music from Jaws plays in my *** th.re are lots of people like me——reasonably comfortable in social situations,no particular ph.bi... 详细信息

关键词： th.re 分寸礼仪英文 party from not see