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丛书名：国外大视野丛书

1999年

作者：（英）道格拉斯·拉蒙特（douglas F.lamont）魏建华译

本书对目前有关全球性观点中有时出现的似是而非的说法发人深省地进行了解答。

ISBN: (纸本)7501143307

本书对目前有关全球性观点中有时出现的似是而非的说法发人深省地进行了解答。

关键词：经济贸易经济国际贸易

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软管充填封口机

包装与食品机械 1989年第4期7卷 46-49页

作者： douglas j. White 岳仁美国Norden包装公司

人们都想了解如何使用软管充填机械,以及这些机械的优点使用范围和功能,想知道怎么选择最合适的机器用于现行和规划中的软管,以满足产品生产的要求。软管的材料,如塑料、金属或复合材料,影响着对机器的选择。然而。

关键词：包装机械软管充填封口机

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Lineage relationship of CD8^＋ T cell subsets is revealed by progressive changes in the epigenetic landscape

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Cellular & Molecular Immunology 2016年第4期13卷 502-513页

作者： j.seph G. Crompton Manikandan Narayanan Suresh Cuddapah Rahul Roychoudhuri Yun j. Wenj.ng Yang Shashank j. Patel Madhusudhanan Sukumar douglas C. Palmer Weiqun Peng Ena Wang Francesco M. Marincola Christopher A. Klebanoff Kej. Zhao j.hn S. Tsang Luca Gatt-inoni Nicholas P. Restifo Surgery Branch National Cancer Institute National Institutes of Health Bethesda MD 20892 USA Cambridge Institute for Medical Research University of Cam bridge Cambridge CB20XY UK Systems Genomics and Bioinformatics Unit Laboratory of Systems Biology National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD 20892 USA Department of Environmental Medicine New York University School of Medicine Tuxedo NY 10987 USA Experimental Transplantation and Immunology Branch National Cancer Institute National Institutes of Health Bethesda MD 20892 USA Department of Physics The George Washington University Washington DC 20052 USA Research Branch Sidra Medical and Research Centre Doha Qatar Infectious Disease and Immunogenetics Section Department of Transfusion Medicine Clinical Center National Institutes of Health Bethesda MD 20892 USA Clinical Investigator Development Program NCI/NIH Bethesda MD 20892 USA Systems Biology Center National Heart Lung and Blood Institute National Institutes of Health Bethesda MD 20892 USA. Lombardi Comprehensive Cancer Center Georgetown University Washington. DC 20007. United States. Bethesda. MD 20892. USA.

To better elucidate epigenetic mechanisms that correlate with the dynamic gene expression program observed upon T-cell differentiation, we investigated the genomic landscape of histone modifications in naive and memory CD8＋ T cells. Using a ChlP-Seq approach coupled with global gene expression profiling, we generated genome-wide histone H3 lysine 4 （H3K4me3） and H3 lysine 27 （H3K27me3） trimethylation maps in naive, T memory stem cells, central memory cells, and effector memory cells in order to gain insight into how histone architecture is remodeled during T cell differentiation. We show that H3K4me3 histone modifications are associated with activation of genes, while H3K27me3 is negatively correlated with gene expression at canonical loci and enhancers associated with T-cell metabolism, effector function, and memory. Our results also reveal histone modifications and gene expression signatures that distinguish the recently identified T memory stem cells from other CD8＋ T-cell subsets. Taken together, our results suggest that CD8＋ lymphocytes undergo chromatin remodeling in a progressive fashion. These findings have maj.r implications for our understanding of peripheral T-cell ontogeny and the formation of immunological memory.

关键词： TRANSCRIPTION FACTOR STEM-CELLS MEMORY EFFECTOR DIFFERENTIATION BET FATE LYMPHOCYTES MAINTENANCE GENERATION

Inside server-based applications

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Inside server-based applications

Extracellular quality control in the epididymis

2000年

作者： Reilly douglas j

来源：畅想之星图书光盘版（南... 评论

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Asian j.urnal of Andrology 2007年第4期9卷 500-507页

作者： Gail A. Cornwall H. Henning von Horsten douglas Swartz Seethal j.hnson Kim Chau Sandra Whelly Department of Cell Biology and Biochemistry Texas Tech University Health Sciences Center Lubbock TX 79430 USA

The epididymal lumen represents a unique extracellular environment because of the active sperm maturation process that takes place within its confines. Although much focus has been placed on the interaction of epididymal secretory proteins with spermatozoa in the lumen, very little is known regarding how the complex epididymal milieu as a whole is maintained, including mechanisms to prevent or control proteins that may not stay in their native folded state following secretion. Because some misfolded proteins can form cytotoxic aggregate structures known as amyloid, it is likely that control/surveillance mechanisms exist within the epididymis to protect against this process and allow sperm maturation to occur. To study protein aggregation and to identify extracellular quality control mechanisms in the epididymis, we used the cystatin family of cysteine protease inhibitors, including cystatin-related epididymal spermatogenic and cystatin C as molecular models because both proteins have inherent properties to aggregate and form amyloid. In this chapter, we present a brief summary of protein aggregation by the amyloid pathway based on what is known from other organ systems and describe quality control mechanisms that exist intracellularly to control protein misfolding and aggregation. We then present a summary of our studies of cystatinrelated epididymal spermatogenic （CRES） oligomerization within the epididymal lumen, including studies suggesting that transglutaminase cross-linking may be one mechanism of extracellular quality control within the epididymis. （Asian j.Androl 2007 j.ly; 9： 500-507）

关键词： epididymis protein aggregation extracellular quality control cystatin transglutaminase

Dynapenia in all-cause mortality and its relationship with sedentary behavior in community-dwelling older adults

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Sports Medicine and Health Science 2022年第4期4卷 253-259页

作者： Rizia Rocha Silva Lucas Lima Galvão j.ilson Meneguci douglas de Assis Teles Santos j.ir Sindra Virtuoso j.nior Sheilla Tribess Research Center on Physical Activity Health and AgingDepartment of Sport SciencesInstitute of Health SciencesFederal University of Triângulo MineiroUberabaMinas GeraisBrazil Department of Education University do Estado da BahiaTeixeira de FreitasBahiaBrazil

The aim of the present study was to investigate the relationship of dynapenia combined with sedentary behavior(SB)on the risk of mortality in older adults living in a Brazilian community.A total of 322 participants aged60 years from the ELSIA(Longitudinal Study of Elderly Health in Alcobaça)prospective cohort were *** was diagnosed when the handgrip strength wasj.sted models,the dynapenia and the time spent exposed to SB were analyzed in a combined way,the older adults with worse behavior(high SB and dynapenia)had higher risk ratios for mortality(hazard ratio 2.46;95%confidence interval 1.01–5.97)than the best behavior *** adults with dynapenia are at greater risk for all-cause mortality,which is aggravated by the addition of longer exposure to SB.

关键词： Mortality Muscle strength Aging Sedentary behavior

An implementation strategy to quantify the marine microbial carbon pump and its sensitivity to global change

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National Science Review 2018年第4期5卷 474-480页

作者： Carol Robinson douglas Wallace j.ng-Ho Hyun Luca Polimene Ronald Benner Yao Zhang Ruanhong Cai Rui Zhang Nianzhi j.ao University of East Anglia School of Environmental Sciences Oceanography Department Dalhousie University Hanyang University Department of Marine Science and Convergence Engineering Plymouth Marine Laboratory University of South Carolina Department of Biological Sciences and School of the EarthOcean and Environment State Key Laboratory of Marine Environmental Science and Institute of Marine Microbes and Ecospheres

INTRODUCTION The persistence of the vast pool of recalcitrant dissolved organic carbon(RDOC)in the deep ocean is fundamental to both global carbon cycling and global ***,quantitative understanding of the mechanisms that produce and utilize RDOC is still in its *** from a conceptual framework to quantitative understanding in marine carbon cycling can take the international research community several decades—precious time

关键词： MCP An implementation strategy to quantify the marine microbial carbon pump and its sensitivity to global change

Effects of chemical sterilization of the culture media,porous membranes and luminosity on in vitro culture of Eucalyptus grandis×Eucalyptus urophylla

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j.urnal of Forestry Research 2021年第4期32卷 1587-1598页

作者： Letícia Vaz Molinari Denys Matheus Santana Costa Souza Maria Lopes Martins Avelar Sérgio Bruno Fernandes douglas Santos Gonçalves j.lio Cézar Tannure Faria Dulcineia de Carvalho Gilvano Ebling Brondani Department of Forestry Sciences Federal University of LavrasLavrasMinas GeraisBrazil

Hybrid combinations of Eucalyptus have increased due to expansion of plantations into unconventional areas and to the search for higher quality ***,most of these species have difficulties surviving in vitro *** chlorine and sealing systems are often used to reduce contamination and increase gas *** aim of the present study is to evaluate the establishment,multiplication,elongation and adventitious rooting of *** × *** clones(C1 and C2) and four active chlorine concentrations(0.000%,0.001%,0.003%,and 0.005%) were tested in the establishment and multiplication *** sealing forms(W/M,1/M and 3/M) and the same four active chlorine concentrations were applied to the elongation *** luminosities(dark and light)and three sealings(W/M,1/M and 3/M) were tested during adventitious *** chlorine concentration of0.005% led to the lowest fungal contamination rate and to the highest in vitro *** chlorine concentration of 0.003% resulted in the greatest length and highest number of shoots per explant in the multiplication *** were no phytotoxicity problems and the quality of plants grown in an environment with active chlorine was maintained in comparison with those grown in an *** increase in gas exchange in ventilation systems had a positive impact on the in vitro growth and development of plants.

关键词： Asepsis Cloning Gas exchange In vitro propagation

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森林火险等级预报系统评述

世界林业研究 2006年第2期19卷 39-46页

作者：田晓瑞 douglas j.Mcrae 张有慧中国林业科学研究院森林生态环境与保护研究所国家林业局森林保护学重点实验室北京100091 加拿大林务局大湖林业中心山东省冠县苗圃山东冠县252525

对当前世界上主要的森林火险等级系统进行了综述,包括加拿大、美国、澳大利亚以及其他一些国家的森林火险等级系统。对主要森林火险等级系统的组成、结构和发展过程进行了比较,讨论了这些系统应用的局限性。比较了世界上3个应用比较普... 详细信息

对当前世界上主要的森林火险等级系统进行了综述,包括加拿大、美国、澳大利亚以及其他一些国家的森林火险等级系统。对主要森林火险等级系统的组成、结构和发展过程进行了比较,讨论了这些系统应用的局限性。比较了世界上3个应用比较普遍的森林火险等级系统的发展、可燃物类型、输入因子、输出因子和应用范围,认为发展中国的森林火险等级系统采用加拿大的森林火险等级系统(CFFDRS)的技术比较合适。我们可直接应用CFFDRS,然后根据当地气候和可燃物类型对火险等级系统进行校正。

关键词：森林火险火险等级系统评述可燃物类型

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工厂自备电站的发展趋势

锅炉技术 1985年第9期 30-34页

作者： douglas j. Smith 虞月瑾上海发电设备所

很早以前工业界就知道热电站有很高的效率。热电联供是指从一种燃料能源同时生产电力和蒸汽。自上世纪末到本世纪初,欧洲和美国的工业界就开始发展热电站。当时电力工业还处在摇篮时期,发电设备运行不稳

关键词：沸腾床流化床石灰石颗粒热电联供系统燃气轮机热力发动机电力蓄能系统沸腾燃烧锅炉自备电站自备电厂工业界发电设备电力设备