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Acta Pharmaceutica Sinica B 2023年第2期13卷 648-661页

作者： Jian Lu Xuyang Shang Bingyi Yao dongyi sun Jie Liu Yuanjin Zhang He Wang Jingru Shi Huaqing Chen Tieliu Shi Mingyao Liu Xin Wang Changning Maternity and Infant Health Hospital and School of Life Sciences Shanghai Key Laboratory of Regulatory BiologyEast China Normal UniversityShanghai 200241China

Cholesterol is an important precursor of many endogenous *** of cholesterol homeostasis can cause many pathological changes,leading to liver and cardiovascular ***1A is widely involved in cholesterol metabolic network,but its exact function has not been fully ***,we aim to explore how CYP1A regulates cholesterol *** data showed that CYP1A1/2 knockout(KO)rats presented cholesterol deposition in blood and *** serum levels of low-density lipoprotein cholesterol,high-density lipoprotein cholesterol and total cholesterol were significantly increased in KO *** studies found that the lipogenesis pathway(LXRa-SREBP1-SCD1)of KO rats was activated,and the key protein of cholesterol ester hydrolysis(CES1)was ***,lansoprazole can significantly alleviate rat hepatic lipid deposition in hypercholesterolemia models by inducing *** findings reveal the role of CYP1A as a potential regulator of cholesterol homeostasis and provide a new perspective for the treatment of hypercholesterolemia.

关键词： Hyperlipidemia Hypercholesteremia Cholesterol CYP1A Lipidosis LXR CES1 Lansoprazole

原状脱硫石膏聚苯颗粒轻质保温材料的制备与性能

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东南大学学报（自然科学版） 2017年第2期47卷 384-391页

作者：雷东移郭丽萍孙伟东南大学材料科学与工程学院南京211189 东南大学先进土木工程材料协同创新中心南京211189 南大学江苏省土木工程材料重点实验室南京211189

在原状脱硫石膏胶凝体系研究的基础上,针对相关原料对原状脱硫石膏聚苯颗粒轻质保温材料各项性能的影响进行了实验研究.实验结果得到:保温骨料聚苯颗粒与原状脱硫石膏胶凝体系的最佳体积比为82.6%;纤维素醚与原状脱硫石膏胶凝体系的最... 详细信息

在原状脱硫石膏胶凝体系研究的基础上,针对相关原料对原状脱硫石膏聚苯颗粒轻质保温材料各项性能的影响进行了实验研究.实验结果得到:保温骨料聚苯颗粒与原状脱硫石膏胶凝体系的最佳体积比为82.6%;纤维素醚与原状脱硫石膏胶凝体系的最佳质量比为0.5%;可再分散乳胶粉与原状脱硫石膏胶凝体系的最佳质量比为0.8%;聚丙烯纤维与原状脱硫石膏胶凝体系的最佳质量比为0.2%,各组分均外掺.根据最佳比制得的保温材料的各项性能均满足《胶粉聚苯颗粒外墙外保温系统》(JG 158—2013)的相关要求.有效解决了原状脱硫石膏的资源化应用问题,为固体废弃物脱硫石膏的综合利用开辟了一条新途径.

关键词：原状脱硫石膏聚苯颗粒聚丙烯纤维纤维素醚可再分散乳胶粉保温材料

Divergent responses of runoff to climate change in the upper basins of the Third Pole dominated by westerlies and monsoon

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Science China Earth Sciences 2024年第8期67卷 2592-2614页

作者： Qikai sun Fengge SU He sun State Key Laboratory of Tibetan Plateau Earth System Environment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100101China

The diverse climates,distribution of snow and glaciers,and geographic locations directly affect the runoff response to climate change in the upper basins of the Third *** present,a comprehensive analysis of runoff variations and their distinct responses to climate change in the westerlies-and monsoon-dominated upper basins is still *** study comprehensively analyzed annual runoff variations in westerlies-dominated basins(the upper basins of the Aksu(UAKS),Syr Darya(USRD),Yarkant(UYK),Hotan(UHT),Amu Darya(UAMD),and Indus(UI))and monsoon-dominated basins(the upper basins of the Yangtze(UYA),Yellow(UYE),Lancang(ULC),Nujiang(UNJ),and Yarlung Zangbo(UYZ))of the Third Pole from 1961 *** multi-source meteorological data and large-scale circulation factors,this study investigated the divergent responses of runoff in the upper basins to climate change,and explored the large-scale circulation mechanisms underlying runoff variations in these upper *** results showed that:(1)The annual runoff in the majority of upper basins(except for the UYE and UYZ)exhibited an increasing trend,and the annual runoff in the UAKS,UYK,and UI showed a significant increasing trend from1961 to *** annual runoff in the upper basins of the Third Pole changed abruptly from decreasing to increasing between the 1980s and 2000s,with the exception of the UYE.(2)The runoff in the monsoon-dominated upper basins has been controlled primarily by changes in precipitation over the past 55 *** contrast,the runoff in the westerlies-dominated upper basins exhibited three distinct long-term responses to climate change:temperature-dominated(UYK and UHT),precipitation-dominated(USRD and UAMD),and the combined influence of precipitation and temperature(UAKS and UI).Since the 1960s,the sensitivity of runoff to warm season temperature changes in the most westerlies-dominated upper basins has decreased,while the response of runoff to precipitation changes has intensified.(3)The stud

关键词： Upper basins of the Third Pole Climate change Westerlies and monsoon Runoff variations Large-scale circulation factors

New perspectives on deep carbon cycling

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Science China Earth Sciences 2024年第8期67卷 2411-2422页

作者： Weidong sun Center of Deep Sea Research Key Laboratory of Ocean Observation and ForecastingInstitute of OceanologyChinese Academy of SciencesQingdao 266071China Laoshan Laboratory Qingdao 266237China University of Chinese Academy of Sciences Beijing 100049China

The proto-atmosphere serves as a crucial starting point for the carbon *** based on atmospheric data from Mars and Venus suggest that Earth's proto-atmosphere contained>110 bar of CO_(2)and>2.6 bar of *** protoatmosphere had over 1000 bar of water vapor during the magma ocean stage,assuming the proto-ocean had a volume of two oceans of *** this stage both water and carbon dioxide were in a supercritical state at the magma-atmosphere *** serpentinization reactions occurred due to rock-water interaction,producing abundant ***,nitrogen is reduced to ammonia,and carbon dioxide to methane,forming carbonate *** proto-atmosphere dominated by methane,ammonia,and hydrogen formed a significant amount of amino acids through *** process is essential not only to the origin of life,but also to the early carbon-nitrogen cycle on *** the Hadean eon,a large amount of CO_(2)was sequestered as carbonate and organic ***,it mainly entered the deep mantle through mantle overturn or *** the mantle transition zone,carbonate undergoes“Redox freezing”,where carbonate is reduced to diamond through oxidation of ferrous iron in the *** the lower mantle,Fe^(2+)undergoes disproportionation reactions,forming Fe^(3+)and metallic *** these,Fe^(3+)mainly resides in bridgmanite,thereby increasing the oxygen fugacity of the lower mantle,while metallic iron falls to the Earth's *** distribution of carbon in the mantle is crucial for deep carbon *** density curves of diamond and mantle peridotite melt intersect at the bottom of the mantle transition zone(about 660 km).This density crossover leads to the accumulation of diamond during the magma ocean *** materials such as subducting slabs enter the lower mantle,compensatory upwelling of lower mantle material *** enters the upper mantle,decomposes,releasing Fe^(3+)ions and oxidizes diamond

关键词： Carbon cycling Proto-atmosphere Amino acids Subduction initiation Passive margin subduction Atmospheric carbon dioxide

宝钢自备电厂锅炉设备用高频焊接螺旋肋片管束的节能效果分析

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上海机械学院学报 1984年第4期 69-79页

作者：马其良孙栋一上海机械学院动力机械工程系上海后方电力处检修工程队

本文阐述锅炉设备使用高频焊接螺旋肋片管束的效果。通过对宝钢电厂35万KW机组1~#锅炉省煤器与姚孟电厂30万KW机组2~#锅炉省煤器的比较,说明了高频焊接螺旋肋片管束在节能、省料和使结构紧凑方面的优越性,并介绍了这种管束在运行中的积... 详细信息

本文阐述锅炉设备使用高频焊接螺旋肋片管束的效果。通过对宝钢电厂35万KW机组1~#锅炉省煤器与姚孟电厂30万KW机组2~#锅炉省煤器的比较,说明了高频焊接螺旋肋片管束在节能、省料和使结构紧凑方面的优越性,并介绍了这种管束在运行中的积灰情况,指出了在锅炉对流受热面中用它来替代常用光管管束的前景。

关键词：高频焊接积灰螺旋肋片管锅炉省煤器光管管束锅炉设备节能效果自备电厂宝钢

Fossil Equidae in the Linxia Basin with Biostratigraphic and Paleozoogeographic Significance

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Acta Geologica Sinica(English Edition) 2024年第1期98卷 1-9页

作者： sun Boyang Key Laboratory of Vertebrate Evolution and Human Origins of the Chinese Academy of Sciences Institute of Vertebrate Paleontology and PaleoanthropologyChinese Academy of SciencesBeijing 100044China

The Linxia Basin is characterized by an abundance of Cenozoic sediments,that contain exceptionally rich fossil *** are abundant in the Linxia Basin,the fossil record of equids in this region including 16 species that represent 10 *** comparison to other classic late Cenozoic areas in China,the Linxia Basin stands out,because the fauna and chronological data accompanying Linxia equids render them remarkably useful for *** anchitheriines in the region,such as Anchitherium and Sinohippus,represent early equids that appeared in the late stages of the middle and late Miocene,*** the equines,most species of Chinese hipparions have been identified in the Linxia Basin and some species of the genera Hipparion and Hippotherium have FAD records for ***,Equus eisenmannae is one of the earliest known species of Equus in the Old World and is well-represented at the Longdan *** species with precise geohistorical distributions can serve as standards for high-resolution chronological units within this *** at the eastern margin of the Tibetan Plateau and subject to considerable uplift,the Linxia Basin has served as a biogeographic transition area for equids throughout the late Cenozoic.

关键词： Equidae Cenozoic biostratigraphy paleozoogeography Linxia Basin

Achieving simultaneously high conversion and high selectivity for light olefins directly producing from syngas

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Science China Chemistry 2024年第3期67卷 753-754页

作者： Yuhan sun Shanxi Research Institute Huairou Research LaboratoryTaiyuan 030032China Institute of Carbon Neutrality ShanghaiTech UniversityShanghai 201210China

The activity and selectivity are two primary indexes of a successful catalyst for chemical reactions. However,achieving a high activity and a high selectivity simultaneously is a long-standing challenge in catalysis, the socalled activity-selectivity trade-off. In the article recently published in Science, a research team led by Prof.

关键词： selectivity simultaneous catalysis

ONE-PARAMETER FINITE DIFFERENCE METHODS AND THEIR ACCELERATED SCHEMES FOR SPACE-FRACTIONAL SINE-GORDON EQUATIONS WITH DISTRIBUTED DELAY

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Journal of Computational Mathematics 2024年第3期42卷 705-734页

作者： Tao sun Chengjian Zhang Haiwei sun School of Mathematics and Statistics Huazhong University of Science and TechnologyWuhan 430074China Hubei Key Laboratory of Engineering Modeling and Scientific Computing Huazhong University of Science and TechnologyWuhan 430074China Department of Mathematics University of MacaoMacaoChina

This paper deals with numerical methods for solving one-dimensional(1D)and twodimensional(2D)initial-boundary value problems(IBVPs)of space-fractional sine-Gordon equations(SGEs)with distributed *** 1D problems,we construct a kind of oneparameter finite difference(OPFD)*** is shown that,under a suitable condition,the proposed method is convergent with second order accuracy both in time and *** implementation,the preconditioned conjugate gradient(PCG)method with the Strang circulant preconditioner is carried out to improve the computational efficiency of the OPFD *** 2D problems,we develop another kind of OPFD *** such a method,two classes of accelerated schemes are suggested,one is alternative direction implicit(ADI)scheme and the other is ADI-PCG *** particular,we prove that ADI scheme can arrive at second-order accuracy in time and *** some numerical experiments,the computational effectiveness and accuracy of the methods are further ***,for the suggested methods,a numerical comparison in computational efficiency is presented.

关键词： Fractional sine-Gordon equation with distributed delay One-parameter finite difference methods Convergence analysis ADI scheme PCG method

Dominant woody plant species recognition with a hierarchical model based on multimodal geospatial data for subtropical forests

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Journal of Forestry Research 2024年第3期35卷 111-130页

作者： Xin Chen Yujun sun State Forestry&Grassland Administration Key Laboratory of Forest Resources&Environmental Management Beijing Forestry UniversityBeijing 100083People's Republic of China

Since the launch of the Google Earth Engine(GEE)cloud platform in 2010,it has been widely used,leading to a wealth of valuable ***,the potential of GEE for forest resource management has not been fully *** extract dominant woody plant species,GEE combined Sen-tinel-1(S1)and Sentinel-2(S2)data with the addition of the National Forest Resources Inventory(NFRI)and topographic data,resulting in a 10 m resolution multimodal geospatial dataset for subtropical forests in southeast *** and texture features,red-edge bands,and vegetation indices of S1 and S2 data were computed.A hierarchical model obtained information on forest distribution and area and the dominant woody plant *** results suggest that combining data sources from the S1 winter and S2 yearly ranges enhances accuracy in forest distribution and area extraction compared to using either data source ***,for dominant woody species recognition,using S1 winter and S2 data across all four seasons was *** terrain factors and removing spatial correlation from NFRI sample points further improved the recognition *** optimal forest extraction achieved an overall accuracy(OA)of 97.4%and a maplevel image classification efficacy(MICE)of 96.7%.OA and MICE were 83.6%and 80.7%for dominant species extraction,*** high accuracy and efficacy values indicate that the hierarchical recognition model based on multimodal remote sensing data performed extremely well for extracting information about dominant woody plant *** the results using the GEE application allows for an intuitive display of forest and species distribution,offering significant convenience for forest resource monitoring.

关键词： Google Earth Engine Sentinel Forest resource inventory data Dominant woody plant species Subtropics Model performance

Complex adaptive system theory,agent-based modeling,and simulation in dominant technology formation

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Journal of Systems Engineering and Electronics 2024年第1期35卷 130-153页

作者： ZHANG Ruihan sun Bing Glorious sun School of Business and Management Donghua UniversityShanghai 200051China School of Economics and Management Harbin Engineering UniversityHarbin 150001China

Dominant technology formation is the key for the hightech industry to“cross the chasm”and gain an established foothold in the market(and hence disrupt the regime).Therefore,a stimulus-response model is proposed to investigate the dominant technology by exploring its formation process and ***,based on complex adaptive system theory and the basic stimulus-response model,we use a combination of agent-based modeling and system dynamics modeling to capture the interactions between dominant technology and the socio-technical *** results indicate the following:(i)The dynamic interaction is“stimulus-reaction-selection”,which promotes the dominant technology’s formation.(ii)The dominant technology’s formation can be described as a dynamic process in which the adaptation intensity of technology standards increases continuously until it becomes the leading technology under the dual action of internal and external mechanisms.(iii)The dominant technology’s formation in the high-tech industry is influenced by learning ability,the number of adopting users and ***,a“critical scale”of learning ability exists to promote the formation of leading technology:a large number of adopting users can promote the dominant technology’s formation by influencing the adaptive response of technology standards to the socio-technical landscape and the choice of technology standards by the socio-technical *** is a minimum threshold and a maximum threshold for the role of adaptability in the dominant technology’s formation.(iv)The socio-technical landscape can promote the leading technology’s shaping in the high-tech industry,and different elements have different *** study promotes research on the formation mechanism of dominant technology in the high-tech industry,presents new perspectives and methods for researchers,and provides essential enlightenment for managers to formulate technology strategies.

关键词： complex adaptive system theory agent-based modeling and simulation dominant technology socio-technical landscape adaptation-choice