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基于Volterra模型的预测控制及应用

控制理论与应用 2015年第3期32卷 312-319页

作者：贺静赵众董叶伟北京化工大学信息科学与技术学院北京100029

由于工业实践的需要,非线性预测控制近年来受到广泛地关注.Volterra模型是一类特殊的非线性模型,非常适合描述工业过程中的无记忆非线性对象.传统的基于Volterra模型的控制器合成法及迭代计算预测控制器法计算量大,且不便于处理控制约束... 详细信息

由于工业实践的需要,非线性预测控制近年来受到广泛地关注.Volterra模型是一类特殊的非线性模型,非常适合描述工业过程中的无记忆非线性对象.传统的基于Volterra模型的控制器合成法及迭代计算预测控制器法计算量大,且不便于处理控制约束.非线性模型预测控制求解是典型的非线性规划问题,序列二次规划(sequential quadratic program,SQP)算法是求解非线性规划问题常用方法之一.针对Volterra非线性模型预测控制求解问题,本文将滤子法与一种信赖域SQP算法相结合,提出一种改进SQP算法用于基于非线性Volterra模型的带控制约束的多步预测控制求解,并分析了所提方法的收敛性.工业实例仿真结果证实了所提方法的可行性与有效性.

关键词： Volterra模型滤子法序列二次规划(SQP) 非线性模型预测控制

Traditional Chinese medicine as monotherapy or combined with oseltamivir in the treatment of H1N1 influenza:a systematic review and meta-analysis

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TMR Modern Herbal Medicine 2022年第3期5卷 1-12页

作者： Chun-Ping Gu dong-wei ye Xin Mao Shu-Wen Liu Clinical Pharmacy Center Nanfang HospitalSouthern Medical UniversityGuangzhou 510515China Guangdong Provincial Key Laboratory of New Drug Screening School of Pharmaceutical SciencesSouthern Medical UniversityGuangzhou 510515China

Objective This study aimed to assess the efficacy and safety of traditional Chinese medicine,alone or in combination with oseltamivir,in patients with H1N1 *** In the present study,we searched the Cochrane Central Register of Controlled Trials,PUBMED,EMBASE,Chinese Biomedical Literature Database,China Science and Technology Journal Database,China National Knowledge Infrastructure Database,and WanFang Data for studies published in or before February 8,*** were extracted and checked by two *** Manager 5.4 and STATA statistical software 16.0 were used for the data *** We identified 22 individual studies reporting data from 2292 individuals with H1N1 *** with oseltamivir,the fever clearance duration[MD=-3.99,95%CI(-6.89,-1.09)]and sore throat relief time[MD=-5.39,95%CI(-10.19,-0.59)]in the intervention group of traditional Chinese medicine monotherapy or combined with oseltamivir were *** was the primary component of *** subgroup analyses indicated that Maxingshigan shortened fever clearance time[MD=-3.23,95%CI(-5.60,-0.85)],and also had certain advantages in relieving sore throat[RR=-4.55,95%CI(-10.04,0.95)].However,as for the effective rate,fever duration,cough disappearance time,hospital length of stay,clinical symptoms time as well as viral shedding duration,there were no significant differences between the two ***,no serious adverse effects were reported in the included *** Although we couldn’t get a definitive conclusion due to the small sample sizes and high risk of bias in the included studies,most traditional Chinese medicine showed similar effects to oseltamivir in treating H1N1 *** were showed to have a statistically significant shorter time of fever clearance and sore throat remission when they were used alone or in combination with oseltamivir and were well-tolerated treatment,such as Maxingshigan.

关键词： traditional Chinese medicine maxingshigan oseltamivir H1N1 influenza meta-analysis

Three-dimensional fracture of UO2 ceramic pellets by phase field modeling

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 169-180页

作者： wei Xiong Xuan ye Hongzhang Cheng Xiaoming Liu Institute of Nuclear and New Energy Technology Collaborative Innovation Center of Advanced Nuclear Energy Technology Key Laboratory of Advanced Reactor Engineering and Safety of Ministry of Education Tsinghua University State Key Laboratory of Nonlinear Mechanics Institute of Mechanics Chinese Academy of Sciences School of Engineering Science University of Chinese Academy of Sciences

Fracture is the primary failure type for the UO2ceramic pellets,which are operated under irradiation and thermal processes,and physically confined by the *** this work,by combining closely coupled physical processes of heat conduction,heat transfer,and mechanical deformation with the cohesive phase field framework,we proposed a high-precision modeling of quasistatic cracking of three-dimensional （3D） UO2ceramic fuel pellets under high temperature and *** simulation results agree well with the experimental results,indicating that the proposed method has the potential to capture 3D crack modes in the interested time ***,we studied the relation of the 3D fracture patterns of fuel pellets with the peak power *** was found that the power level plays a critical role in determining the competition between radial and circumferential cracks,as well as transverse penetrating cracks.

关键词： phase field method nuclear fuel pellet coupled thermo-mechanical model thermal fracture

黑水虻幼虫粉替代不同比例鱼粉对加州鲈生长、机体健康和肌肉品质的影响

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水生生物学报 2024年第3期48卷 372-383页

作者：游翠红李鸿伟周萌林蠡董烨玮谭小红黄燕华仲恺农业工程学院健康养殖创新研究院&动物科技学院广州510225

配制4组等氮等脂(45%蛋白,15%脂肪)的配合饲料,对照组含有30%的鱼粉(FM30),其他3组分别用黑水虻(Hermitia illucens)幼虫粉替代16.67%(FM25)、33.33%(FM20)、50%(FM15)鱼粉,在室内循环水养殖系统中投喂加州鲈(Micropterus salmoides)幼鱼8周,探究用黑水虻幼虫粉替代不同比例鱼粉对加州鲈生长性能、机体健康和肌肉品质的影响。结果显示,各组加州鲈在终末体质量、增重率、特定生长率、成活率上无显著差异(P>0.05),FM20组鱼拥有较高的增重率和特定生长率,其饲料系数最低,显著低于FM15和FM25组(P<0.05)。用黑水虻幼虫粉部分替代鱼粉,降低了全鱼和肝脏的脂肪含量、血清甘油三酯含量、肝脏的C14﹕0、C16﹕0、C18﹕1n-9和C18﹕3n-3的含量和肌肉的DHA含量,但是,增加了肝脏C18﹕0、DHA、EPA和C22﹕5n-3的含量,对肌肉和肝脏的氨基酸组成影响较小。与对照组相比,FM20组鱼前肠和肝脏的丙二醛含量显著增加(P<0.05),前肠和血清的碱性磷酸酶活性显著降低(P<0.05),前肠上皮出现肠绒毛破损、肠皱褶粘连等结构受损情况,前肠脂肪酶活性、肌肉脂肪含量和全鱼粗蛋白含量、肝脏DHA含量最高。上述结果表明,加州鲈具有内源合成高度不饱和脂肪酸的能力;在加州鲈幼鱼的配合饲料中可以用黑水虻幼虫粉替代50%鱼粉(FM15),鱼粉的添加量最低可降到15%,不影响加州鲈的生长性能,但是,最适宜的黑水虻幼虫粉替代水平是替代33.33%鱼粉。研究成果为研制营养组成科学合理、成本低的加州鲈配合饲料提供资料。

关键词：鱼粉替代生长性能脂肪酸黑水虻幼虫加州鲈

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上海市心理卫生服务评价指标体系构建研究

中国卫生资源 2017年第5期20卷 426-431页

作者：吴成伟董旻晔李国红上海交通大学公共卫生学院上海200025 上海交通大学中国医院发展研究院卫生技术评估研究所上海200025

目的 :探索建立心理卫生服务体系评价指标体系。方法 :首先通过文献研究和焦点小组访谈构建心理卫生服务评价指标体系框架,然后采用德尔菲法经过两轮专家咨询对指标体系优化,并结合模糊综合评判法确定三级指标的权重。结果 :两轮咨询专... 详细信息

目的 :探索建立心理卫生服务体系评价指标体系。方法 :首先通过文献研究和焦点小组访谈构建心理卫生服务评价指标体系框架,然后采用德尔菲法经过两轮专家咨询对指标体系优化,并结合模糊综合评判法确定三级指标的权重。结果 :两轮咨询专家积极系数分别为83.3%和100.0%,专家对一级指标的权威程度均高于0.8。构建了由精神卫生政策和组织协调机制、心理卫生服务、资源配置、心理健康教育和健康促进、监测和研究5个一级指标、13个二级指标和52个三级指标组成的心理卫生服务评价指标体系。结论 :建立的心理卫生服务评价指标体系覆盖了心理卫生服务政策、服务内容和资源配置等关键评估要素,对促进心理卫生服务体系发展能发挥重要作用。

关键词：心理卫生服务体系焦点小组访谈德尔菲法评价指标体系

两种不同会阴保护技术在自然分娩中的效果比较

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护理实践与研究 2017年第1期14卷 75-76页

作者：韦东梅叶小丽韦秀妮广西贵港市妇幼保健院护理部贵港市537100

目的:探讨两种不同保护会阴技术在自然分娩中的效果。方法:将2014年8月~2015年11月我院收治的600例自然分娩的初产妇随机等分为观察组和对照组,观察组采用自由体位单手保护会阴技术,对照组采用传统保护会阴技术,观察两组产妇产程疼痛级... 详细信息

目的:探讨两种不同保护会阴技术在自然分娩中的效果。方法:将2014年8月~2015年11月我院收治的600例自然分娩的初产妇随机等分为观察组和对照组,观察组采用自由体位单手保护会阴技术,对照组采用传统保护会阴技术,观察两组产妇产程疼痛级别、第二产程时间、产后出血率、会阴裂伤发生率、会阴侧切率及新生儿窒息率等发生情况。结果:两组产妇的产程疼痛级别、产后出血率、会阴裂伤、会阴侧切率、新生儿窒息率比较均有统计学意义(P<0.05)。结论:自由体位单手保护会阴接生技术有效降低会阴侧切、减少会阴损伤,有效减轻产妇产程疼痛,缩短第二产程时间,减少产后出血及新生儿窒息的发生,提高产科质量,值得临床推广应用。

关键词：自由体位单手保护会阴接生技术初产妇自然分娩

The compound(E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one alleviates neuroinflammation and cognitive impairment in a mouse model of Alzheimer's disease

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Neural Regeneration Research 2025年第11期20卷 3330-3344页

作者： Xueyan Liu wei Wu Xuejuan Li Chengyan Wang Ke Chai Fanru Yuan Huijuan Zheng Yuxing Yao Chenlu Li Zu-Cheng ye Daijun Zha Department of Medicinal Chemistry School of PharmacyFujian Medical UniversityFuzhouFujian ProvinceChina Fujian Provincial Key Laboratory of Brain Aging and Neurodegenerative Diseases School of Basic Medical SciencesFujian Medical UniversityFuzhouFujian ProvinceChina Institute of Laboratory Animal Center Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Neurosurgery Neurosurgery Research InstituteThe First Affiliated HospitalFujian Medical UniversityFuzhouFujian ProvinceChina Department of Hyperbaric Oxygen National Regional Medical CenterBinhai Campus of the First Affiliated HospitalFujian Medical UniversityFuzhouFujian ProvinceChina

Previous studies have shown that the compound(E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one(D30),a pyromeconic acid derivative,possesses antioxidant and anti-inflammatory properties,inhibits amyloid-β aggregation,and alleviates scopolamine-induced cognitive impairment,similar to the phase Ⅲ clinical drug *** this study,we established a mouse model of Alzheimer's disease via intracerebroventricular injection of fibrillar amyloid-β to investigate the effect of D30 on fibrillar amyloid-β-induced *** results showed that D30 alleviated fibrillar amyloid-β-induced cognitive impairment,promoted fibrillar amyloid-β clearance from the hippocampus and cortex,suppressed oxidative stress,and inhibited activation of microglia and astrocytes.D30 also reversed the fibrillar amyloid-β-induced loss of dendritic spines and synaptic protein ***,we demonstrated that exogenous fibrillar amyloid-βintroduced by intracerebroventricular injection greatly increased galectin-3 expression levels in the brain,and this increase was blocked by *** the role of D30 in clearing amyloid-β,inhibiting neuroinflammation,protecting synapses,and improving cognition,this study highlights the potential of galectin-3 as a promising treatment target for patients with Alzheimer's disease.

关键词： Alzheimer's disease amyloid-β astrocyte cognitive impairment D30 dendritic spines galectin-3 microglia neuroinflammation neuron

An efficient method for collision-free and jerk-constrained trajectory generation with sparse desired way-points for a flying robot

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Science China(Technological Sciences) 2021年第8期64卷 1719-1731页

作者： CHEN YongXue dong wei DING ye State Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong UniversityShanghai200240China

In this paper,an efficient approach is developed to plan jerk-constrained smooth trajectories passing through desired way-points with allowable accuracy for an autonomous ***,based on the B-spline model,we introduce the sequential convex programming(SCP)into the flexible path planning method to satisfy the way-points *** approximating the quadrotor and obstacles as spheres and directed planes,the length-optimal and collision-free path planning problem is formulated as a nonconvex optimization problem and solved by *** initial C^(3) continuous path curve for optimization is constructed efficiently based on a proposed strategy of generating new way-points near the obstacles without the need to calculate the embedding distance between the curve and the *** this basis,the time-optimal speed planning problem is addressed in two *** the first step,the forward-backward approach is introduced to solve the problem under the chord error,velocity,and acceleration constraints by changing the variables and deforming the *** by relaxing the constraints appropriately,the problem under jerk constraints is formulated into a linear programming(LP)*** feasibility of the proposed approach is verified through simulations and an indoor navigation *** proposed approach can generate a C^(3) continuous collision-free trajectory that passes through the sparse desired way-points with allowable accuracy while guaranteeing the chord error,velocity,acceleration,and jerk *** the number of sample points is 3000,the proposed speed planning method reduces the calculation time by 40%compared to an existing method.

关键词： collision avoidance speed optimization motion planning sequential convex programming quadrotor

Prussian Blue Analogue‑Templated Nanocomposites for Alkali‑Ion Batteries:Progress and Perspective

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Nano-Micro Letters 2025年第1期17卷 216-261页

作者： Jian‑En Zhou Yilin Li Xiaoming Lin Jiaye ye Key Laboratory of Theoretical Chemistry of Environment Ministry of EducationSchool of ChemistrySouth China Normal UniversityGuangzhou 510006People’s Republic of China School of Chemistry and Physics Faculty of ScienceQueensland University of Technology2 George StreetBrisbaneQLD 4000Australia Centre for Materials Science Queensland University of Technology2 George StreetBrisbaneQLD 4000Australia

Lithium-ion batteries(LIBs)have dominated the portable electronic and electrochemical energy markets since their commercialisation,whose high cost and lithium scarcity have prompted the development of other alkali-ion batteries(AIBs)including sodium-ion batteries(SIBs)and potassium-ion batteries(PIBs).Owing to larger ion sizes of Na^(+)and K^(+)compared with Li^(+),nanocomposites with excellent crystallinity orientation and well-developed porosity show unprecedented potential for advanced lithium/sodium/potassium *** enticing open rigid framework structures,Prussian blue analogues(PBAs)remain promising self-sacrificial templates for the preparation of various nanocomposites,whose appeal originates from the well-retained porous structures and exceptional electrochemical activities after thermal *** review focuses on the recent progress of PBA-derived nanocomposites from their fabrication,lithium/sodium/potassium storage mechanism,and applications in AIBs(LIBs,SIBs,and PIBs).To distinguish various PBA derivatives,the working mechanism and applications of PBA-templated metal oxides,metal chalcogenides,metal phosphides,and other nanocomposites are systematically evaluated,facilitating the establishment of a structure–activity correlation for these *** on the fruitful achievements of PBA-derived nanocomposites,perspectives for their future development are envisioned,aiming to narrow down the gap between laboratory study and industrial reality.

关键词： Prussian blue analogues Self-sacrificial template Lithium-ion batteries Sodium-ion batteries Potassium-ion batteries