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Relationship between ABO blood groups and carcinoma of esophagus and cardia in Chaoshan inhabitants of China

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World Journal of Gastroenterology 2001年第5期7卷 657-661页

作者： Min Su~1 Shan-Ming Lu~1 dong-ping tian~1 Hu Zhao~1 Xiao-Yun Li~2 De-Rui Li~3 Zhi-Chao Zheng~4 1 Department of Pathology,2 Tumor Hospital,3,4 Second Teaching Hospital,Shantou University Medical College,Shantou 515031,China Department of Pathology Shantou University Medical College Shantou 515031China. minsu@***

AIM:To study the relationship between ABO blood groups and carcinoma of esophagus and cardia in Chaoshan inhabitants of China, which is a unique Littoral high-risk area of esophageal carcinoma in China. The poor communication and transportation in the past has made Chaoshan a relatively closed area and kept its culture and custure of old China thousand years ago. METHODS: Data on age, sex, ABO blood type and X-ray or pathological diagnose of the patients with carcinoma of esophagus or cardia were collected from the Tumor Hospital. First Affiliated Hospital, Second Affiliated Hospital of Shantou University Medical College; and the Central Hospital of Shantou and the Central Hospital of Jieyang. A total of 6685 patients with esophageal carcinoma (EC) and 2955 patients with cardiac cancer (CC) in Chaoshan district were retrospectively assessed for their association with ABO blood groups. RESULTS: The distribution of ABO blood groups in patients with EC or CC was similar to the normal local population in Chaoshan. However, blood group B in male patients with CC and in the patients with carcinoma in the upper third esophagus was 2.3% and 4.7% higher than the corresponding controls. The relative risk B O was 1.1415 (P<0.05) and 1.2696 (P<0.05), respectively. No relationship was found between ABO blood groups and tumor differentiation. CONCLUSION: ABO blood group B is associated with the incidence of CC in male individuals and carcinoma in the upper third esophagus. The distribution of ABO blood groups varies in the different geographical and ethnic groups. As a result, proper controls are very important for such studies.

关键词： ABO Blood-Group System Cardia China Esophageal Neoplasms Female Gene Frequency Genetic Predisposition to Disease Humans Male Research Support, Non-U.S. Gov't Retrospective Studies Risk Factors Sex Distribution Stomach Neoplasms

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基于OpenGL的工业化机器人仿真研究

重庆师范大学学报（自然科学版） 2013年第2期30卷 60-64页

作者：董天平马燕刘伦鹏重庆师范大学计算机与信息科学学院重庆401331 重庆通信学院基础实验中心重庆400035 重庆师范大学物理与电子工程学院重庆401331

以工业机器人仿真系统为背景,介绍了机器人的发展历程,重点描述了工业化机器人仿真开发的方法。该方法掌握较为容易,开发成本低,具有良好的可扩展性。在此基础上,文章设计并实现了基于OpenGL的工业机器人仿真系统,包括虚拟仿真环境的搭... 详细信息

以工业机器人仿真系统为背景,介绍了机器人的发展历程,重点描述了工业化机器人仿真开发的方法。该方法掌握较为容易,开发成本低,具有良好的可扩展性。在此基础上,文章设计并实现了基于OpenGL的工业机器人仿真系统,包括虚拟仿真环境的搭建、运动学分析和三维模型的绘制。最后,研究了OpenGL在机器人图形仿真系统中的具体应用通适代码封装使得工业机器人图形建模变得简易可行,并分析了工业机器人系统结构。探讨了该系统的运动学和逆运动学实现方法,取得了良好的效果。该仿真系统的研究方法也能够为其他场合的应用提供一定的参考价值。

关键词：工业机器人图形仿真 OpenGL

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QoS组播路由的模糊遗传算法

计算机科学 2004年第4期31卷 50-54页

作者：陈萍董天临华中科技大学电子与信息系武汉430074

已有的QoS组播路由算法都假设已知网络全局的精确状态,而且QoS约束都以确定性界限来表达。然而在实际的网络环境中,网络节点根本无法获得网络全局的精确状态,而且QoS约束完全用确定性界限来表达也存在一定的局限性。本文将模糊集合论的... 详细信息

已有的QoS组播路由算法都假设已知网络全局的精确状态,而且QoS约束都以确定性界限来表达。然而在实际的网络环境中,网络节点根本无法获得网络全局的精确状态,而且QoS约束完全用确定性界限来表达也存在一定的局限性。本文将模糊集合论的基本原理应用于QoS组播路由问题,充分考虑网络节点所获信息的模糊性和随机性,以及QoS约束条件的模糊界限这一客观存在的性质,提出一种新的QoS组播路由的模糊遗传算法FG。仿真实验表明.该算法是可靠且有效的。

关键词： QoS 服务质量组播路由算法模糊遗传算法模糊数学网络管理计算机网络

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军队院校《C语言程序设计》教学策略研究

计算机工程与科学 2016年第A1期38卷 38-42页

作者：周俊董天平李卫东罗琳赵瑞华重庆通信学院基础实验中心重庆400035 重庆通信学院军事信息网络工程教研室重庆400035

《C语言程序设计》是军队院校学员学习计算机编程的基础课程。如何优化《C语言程序设计》课程的教学策略,一直是广大计算机从教工作者关心的焦点问题。基于该课程的教学准备和教学实施过程,首先梳理并提出了在《C语言程序设计》教学中... 详细信息

《C语言程序设计》是军队院校学员学习计算机编程的基础课程。如何优化《C语言程序设计》课程的教学策略,一直是广大计算机从教工作者关心的焦点问题。基于该课程的教学准备和教学实施过程,首先梳理并提出了在《C语言程序设计》教学中存在的问题;接着,针对这些问题给出了相应的解决策略,通过多种教学手段相互结合,充分增强学员的学习积极性,提高课程的教学效率;最后,指出了所提出的教学策略在提高《C语言程序设计》课程质量中的积极作用。

关键词： C语言教学策略课程质量

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士官“计算机基础”课程教学策略研究

计算机工程与科学 2014年第A2期36卷 92-96页

作者：周俊肖春霞董天平李卫东游苑重庆通信学院基础部重庆400035

如何有效提高士官教学授课质量已经成为广大教员普遍关注的问题。针对士官学习的特点和计算机基础课程教学现状,应用任务驱动教学方法,突出网络教学软件在提高士官计算机课程教学质量中的优势及价值,通过调查分析,最终验证了新型的教学... 详细信息

如何有效提高士官教学授课质量已经成为广大教员普遍关注的问题。针对士官学习的特点和计算机基础课程教学现状,应用任务驱动教学方法,突出网络教学软件在提高士官计算机课程教学质量中的优势及价值,通过调查分析,最终验证了新型的教学策略能够较好地提升士官计算机基础课程的教学效率。

关键词：教学策略士官教学计算机应用

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聚合物胶束口服吸收机制的研究进展

沈阳药科大学学报 2010年第8期27卷 669-674页

作者：陈东丁平田邓意辉沈阳药科大学药学院辽宁沈阳100016

目的对聚合物胶束作为口服给药载体的研究方法和吸收机制进行综述。方法参考近年来国内外文献共19篇,总结有关聚合物胶束作为口服给药载体的研究,对其中涉及到的口服吸收机制做以分类和总结。结果目前在聚合物的口服吸收常用的研究方法... 详细信息

目的对聚合物胶束作为口服给药载体的研究方法和吸收机制进行综述。方法参考近年来国内外文献共19篇,总结有关聚合物胶束作为口服给药载体的研究,对其中涉及到的口服吸收机制做以分类和总结。结果目前在聚合物的口服吸收常用的研究方法有Caco-2细胞模型、小肠翻转模型和动物模型,共同作为研究聚合物口服吸收机制的手段。聚合物胶束作为药物载体口服的吸收机制分为:a.通过抑制P-糖蛋白增加吸收;b.以胞饮形式吸收;c.经被动扩散;d.与胆汗相关的吸收。结论对聚合物胶束作为口服给药载体的研究方法和吸收机制进行了报道,为聚合物口服研究提供了参考。

关键词：聚合物胶束口服生物利用度吸收机制

Research status and prospects of the fractal analysis of metal material surfaces and interfaces

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 20-38页

作者： Qinjin Dai Xuefeng Liu Xin Ma Shaojie tian Qinghe Cui Beijing Advanced Innovation Center for Materials Genome Engineering University of Science and Technology BeijingBeijing 100083China Beijing Laboratory of Metallic Materials and Processing for Modern Transportation University of Science and Technology BeijingBeijing 100083China Laboratory for Advanced Materials Processing of Ministry of Education University of Science and Technology BeijingBeijing 100083China School of Mechanical and Electrical Engineering Xinjiang Institute of EngineeringUrumqi 830023China

As a mathematical analysis method,fractal analysis can be used to quantitatively describe irregular shapes with self-similar or self-affine *** analysis has been used to characterize the shapes of metal materials at various scales and *** methods make it difficult to quantitatively describe the relationship between the regular characteristics and properties of metal material surfaces and ***,fractal analysis can be used to quantitatively describe the shape characteristics of metal materials and to establish the quantitative relationships between the shape characteristics and various properties of metal *** the perspective of two-dimensional planes and three-dimensional curved surfaces,this paper reviews the current research status of the fractal analysis of metal precipitate interfaces,metal grain boundary interfaces,metal-deposited film surfaces,metal fracture surfaces,metal machined surfaces,and metal wear *** relationship between the fractal dimensions and properties of metal material surfaces and interfaces is *** from three perspectives of fractal analysis,namely,research scope,image acquisition methods,and calculation methods,this paper identifies the direction of research on fractal analysis of metal material surfaces and interfaces that need to be *** is believed that revealing the deep influence mechanism between the fractal dimensions and properties of metal material surfaces and interfaces will be the key research direction of the fractal analysis of metal materials in the future.

关键词： metal material surfaces and interfaces fractal analysis fractal dimension homogeneity

Construction and Cleavage Characterization of Single Targeted Multi-ribozyme Expression Systems in vitro

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Chemical Research in Chinese Universities 2009年第4期25卷 506-512页

作者： tian Sheng-Li XU dong-ping OHNUMA Takao Shenzhen Key Laboratory of Microbiology and Gene Engineering College of Life Sciences Shenzhen University Shenzhen 518060 P. R. China The 302 Hospital of Beijing Beijing 100039 P R. China Mount Sinai School of Medicine New York 10029 USA

In order to clarify cleavage efficiency of a multi-ribozyme expression system on their substrates,plasmids containing 20 cis-acting hammerhead ribozymes for self-cleavage and 10 trans-acting hammerhead ribozymes targeted on MDR1 and MRP1 substrates,the target plasmids pGEM-MDR1 and pGEM-MRP1 were constructed by employing PCR and DNA *** endonuclease＇s digestion and DNA sequencing confirmed exactness of the multi-ribozyme expression systems and the target *** repeated self-cleavage tests revealed that the cisacting hammerhead ribozymes in the multi-ribozyme expression system were able to cleave themselves and trans-acting hammerhead ribozymes 196 Rz and 210 Rz were *** cleavage efficiencies of liberated ribozymes on their targets were evaluated in vitro and the results indicate that 196 Rz and 210 Rz were able to cleave the MDR1 and MRP1 RNA *** profile of cleavage reaction shows that the cleavage efficiencies were correlated with the numbers of transacting hammerhead ribozymes contained in the multi-ribozyme expression systems,as well as the multi-ribozyme system is much better than the single *** of various concentrations of Mg^2＋ reveals that ribozyme cleavage reactions were dependent on Mg^2＋ *** plot of lg（kobs） ***[Mg^2＋] displays a linear relationship in the concentration range observed（2.5―20 mmol/L）.

关键词： Multi-ribozyme expression systems Hammerhead ribozyme RNA substrate

黄芩苷与苦参碱分子间相互作用的量子化学计算与验证

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原子与分子物理学报 2025年第4期42卷 8-14页

作者：董志舒启江田爽王皎侯安国王文苹云南中医药大学中药学院云南省南药可持续利用重点实验室昆明650500

为探究苦参碱能极大增强黄芩苷在水中的溶解度的原因,采用量子计算对二者反应过程及共存状态进行分析,并使用单晶衍射和红外图谱验证计算结果.本研究表明,黄芩苷和苦参碱并非简单的以非共价作用相结合,二者存在质子转移现象,反应生成黄... 详细信息

为探究苦参碱能极大增强黄芩苷在水中的溶解度的原因,采用量子计算对二者反应过程及共存状态进行分析,并使用单晶衍射和红外图谱验证计算结果.本研究表明,黄芩苷和苦参碱并非简单的以非共价作用相结合,二者存在质子转移现象,反应生成黄芩苷阴离子和苦参碱阳离子,以静电作用为主导形成共无定型物,导致水溶性极大增加.

关键词：苦参碱黄芩苷质子转移离子共无定型物