检索结果-南通市图书馆

Adrenomedullin: an important participant in neurological diseases

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2020年第7期15卷 1199-1207页

作者： Feng-Jiao Li Si-Ru Zheng dong-mei wang College of Life Sciences Laboratory of Neuroendocrinology Provincial Key Laboratory of Developmental Biology and Neuroscience Fujian Normal University

Adrenomedullin,a peptide with multiple physiological functions in nervous system injury and disease,has aroused the interest of *** review summarizes the role of adrenomedullin in neuropathological disorders,including pathological pain,brain injury and nerve regeneration,and their *** a newly characterized pronociceptive mediator,adrenomedullin has been shown to act as an upstream factor in the transmission of noxious information for various types of pathological pain including acute and chronic inflammatory pain,cancer pain,neuropathic pain induced by spinal nerve injury and diabetic *** of glia-neuron signaling networks in the peripheral and central nervous system by adrenomedullin is involved in the formation and maintenance of morphine *** has been shown to exert a facilitated or neuroprotective effect against brain injury including hemorrhagic or ischemic stroke and traumatic brain ***,adrenomedullin can serve as a regulator to promote nerve regeneration in pathological ***,adrenomedullin is an important participant in nervous system diseases.

关键词： adrenomedullin brain injury glia mechanism morphine tolerance neural regeneration neuroprotective effect pathological pain regeneration sensitization target

Transepithelial photorefractive keratectomy mode using SCHWIND-ESIRIS excimer laser:initial clinical results

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2012年第3期5卷 334-337页

作者： dong-mei wang, Jian-Feng He Eye Laser Department Liuzhou Eye Hospital Liuzhou Red Cross Association Hospital Liuzhou 545001 Guangxi Zhuang Autonomous Region China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou 510060 Guangdong Province China Department of Ophthalmology the First Affiliated Hospital of Guangxi Medical University Nanning 530021 Guangxi Zhuang Autonomous Region China

AIM: To evaluate postoperative pain, uncorrected visual acuity (UCVA), and cornea haze value after transepithelial photorefractive keratectomy (T-PRK) performed with aspherical ablation profile using SCHWIND ESIRIS excimer laser. METHODS: Retrospective case series. Fifty-nine eyes (32 patients) with myopia associated with or without astigmatism underwent phototherapeutic keratectomy (PTK) followed by photorefractive keratectomy (PRK) which performed by Optimized Refractive Keratecomy (ORK)-CAM software based on aspherical ablation profile using SCHWIND ESIRIS excimer laser. Postoperative pain scale was measured on a questionnaire through five levels. Haze was graded by five grades, and UCVA, manifest refraction spherical equivalent (MRSE) were analyzed. RESULTS: Mean pain level was (1.37 +/- 0.613) (range: 1 to 3), the mean time picking out the soft contact lens was (6.22 +/- 1.73) days, at 3 months, UCVA was 1.0 for 40 eyes (67.8%), 0.5 for all eyes (100.0%). The UCVA was significantly less than the preoperative best spectacle corrected visual acuity (BSCVA) (t=-2.84, P=0.006), haze value was (0.27 +/- 0.25), no patients had a haze grade up to 2. Mean MRSE was (0.76 +/- 0.96) diopter(D) by 3 months. CONCLUSION: The outcomes from this study show that using the SCHWIND ESIRIS aspherical ablation profile for transepithelial PRK has a good visual result. The primary advantage is related to a spherical ablation profile, automatically considers the ablation volume of the stroma and the accurate and smooth removal of the epithelium with PTK. Additional studies are needed to determine long-term outcomes.

关键词： myopia surgery transepithelial photorefractive keratectomy phototherapeutic keratectomy

Syntheses and Crystal Structures of Calix[4]arene Dithiocarbazate Schiff Bases

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2010年第4期26卷 572-577页

作者： SUN Jing LIU dong-mei wang Jin-xiang YAN Chao-guo College of Chemistry and Chemical Engineering Yangzhou University Yangzhou 225002 P. R. China

The regioselective syntheses of novel p-tert-butylcalix[4]arenes with functional aldehyde and dithiocarbazate Schiff base groups were carried out. p-tert-Butylcalix[4]arene was alkylated with o-, p-（ω-chloroalkoxy）- benzaldehydes in the system of K2CO3/KI/CH3CN to give calixarene 1,3-dialdehydes. Then the condensation reactions of active calixarene aldehydes with S-methyl and S-benzyldithiocarbazate, calixarene sulfur-containing Schiff bases were efficiently obtained in satisfied yields. The single crystal analysis of the four representative products shows that calixarene aldehydes and Schiff bases exist in cone conformation and there are interesting intermolecular hydrogen-bands and π...π interaction in the crystals.

关键词： Calixarene Alkvlation S-Alkvldithiocarbazate Schiff base: Crystal structure

Analysis of Simple Sequence Repeats in Genomes of Rhizobia

在线全文

学校读者我要写书评

暂无评论

Agricultural Sciences in China 2008年第10期7卷 1189-1195页

作者： GAO Ya-mei HAN Yi-qiang TANG Hui SUN dong-mei wang Yan-jie wang Wei-dong College of Life Science and Technology Heilongjiang August First Land Reclamation University Daqing 163319 P.R.China

Simple sequence repeats （SSRs） or microsatellites, as genetic markers, are ubiquitous in genomes of various organisms. The analysis of SSR in rhizobia genome provides useful information for a variety of applications in population genetics of rhizobia. We analyzed the occurrences, relative abundance, and relative density of SSRs, the most common in Bradyrhizobium japonicum, Mesorhizobium loti, and Sinorhizobium meliloti genomes se- quenced in the microorganisms tandem repeats database, and SSRs in the three species genomes were compared with each other. The result showed that there were 1 410, 859, and 638 SSRs in B. japonicum, M. loti, and S. meliloti genomes, respectively. In the genomes of B. japonicum, M. loti, and S. meliloti, tetranucleotide, pentanucleotide, and hexanucleotide repeats were more abundant and indicated higher mutation rates in these species. The least abundance was mononucleotide repeat. The SSRs type and distribution were similar among these species.

关键词： rhizobium genome simple sequence repeat

Kinematics of hip,knee,ankle of the young and elderly Chinese people during kneeling activity

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第10期13卷 831-838页

作者： Hai ZHOU dong-mei wang Tao-ran LIU Xiang-sen ZENG Cheng-tao wang Institute of Biomedical Manufacturing and Life Quality Engineering School of Mechanical and Power Energy EngineeringShanghai Jiao Tong UniversityShanghai 200240China

Objective:The purpose of this study was to measure the kinematics of the lower limbs of Chinese people during normal kneeling activity,as such data could be valuable in designing joint prosthesis and arthroplasty that meet the needs of Chinese citizens' daily ***:Thirty young and twenty elderly Chinese participants with no personal history of joint diseases were recruited,and matched by age(average age:23.8 years for the young group,60.8 years for the elderly group).Each participant performed six trials during which three-dimensional(3D) kinematics data were collected and the means of the 3D angles of the ankle,knee,and hip joints of two groups were ***:There were no obvious differences between the two groups in the knee and ankle *** mean range of knee flexion was 139.6° for the young group and 140.9° for the elderly *** mean range of ankle flexion was 35.7° for the young group and 37.6° for the elderly *** maximal eccentric flexion at the hip joint was 67.5° for the young group compared to 100.5° for the elderly ***:The elderly uses more hip flexion angles than the young when assuming the kneeling *** ranges of motion obtained during kneeling activity are greater than the reported mean ranges of motion achieved following joint *** data could be valuable in establishing criteria for lower limb prosthetics and rehabilitation protocol for the Chinese population.

关键词： Joint angle Kneeling Kinematics Chinese people

Synthesis and cytotoxicity evaluation of a novel justicidin G analogue and its phosphate ester

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2014年第7期25卷 1044-1046页

作者： Sheng-Peng wang Yuan-Feng Tong dong-mei wang Nan wang Zheng Yan Ping Huang Song Wu State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaPeking Union Medical College and Chinese Academy of Medical Sciences Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation Institute of Materia MedicaPeking Union Medical College and Chinese Academy of Medical Sciences

The novel justicidin G analogue 13 and its phosphate ester 15 were synthesized as potential anticancer agents in several steps starting from commercially available methyl gallate and veratraldehyde. The cytotoxicity of the intermediates was tested against HCT-8, BEL-7402, KETR3, HELA, BGC-823, KB and MCF-7 cell lines by the MTT test, and compound 15 exhibited significant cytotoxicity in HELA and KB cell lines.

关键词： Justicidin G Analogue Phosphate ester Antitumor activity Synthesis

Free-Standing Membrane Liquid-State Platform for SERS-Based Determination of Norfloxacin in Environmental Samples

在线全文

学校读者我要写书评

暂无评论

Journal of Analysis and Testing 2021年第3期5卷 217-224页

作者： Jing Liu Wen Liu Sha-Na Zhou dong-mei wang Zheng-Jun Gong mei-Kun Fan Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengdu 610031China

Surface-enhanced Raman scattering(SERS)has been widely used in various fields due to high sensitivity,but it is hindered by its low ***,we explored a highly reproducible free-standing liquid-state platform(FSM)for monitoring norfloxacin(NOR)in the environmental *** optimizing the types of nanoparticles(NPs)and pH value in NOR solution,the relative standard deviation(RSD)of FSM SERS analysis can be stabilized below 10%(n≥8),and the R^(2)of the calibration curve in the range of 20μg/L-100μg/L was *** addition,the results showed that the limit of detection(LOD)(3σ/k)of NOR was 1.3μg/***,the NOR in the spiked samples was successfully quantified by FSM,and the recovery rate exceeded 95%.The proposed method has the potential for rapid analysis of drug residues in environmental samples.

关键词： SERS Norfloxacin Drug residues Environmental samples FSM

Quantum reflection of a Bose-Einstein condensate with a dark soliton from a step potential

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2021年第12期30卷 214-221页

作者： dong-mei wang Jian-Chong Xing Rong Du Bo Xiong Tao Yang Shaanxi Key Laboratory for Theoretical Physics Frontiers Institute of Modern PhysicsNorthwest UniversityXi’an 710127China School of Science Wuhan University of TechnologyWuhan 430070China School of Physics Northwest UniversityXi’an 710127China Peng Huanwu Center for Fundamental Theory Xi’an 710127China

We study dynamical behaviors of a Bose-Einstein condensate(BEC)containing a dark soliton reflected from potential wells and potential barriers,*** orientation angle of the dark soliton and the width of the potential change play key roles on the reflection probability *** of the reflection probability with respect to the orientation angleθof the dark soliton can be well described by a cosine function Rs~cos[λ(θ-π/2)],whereλis a parameter determined by the width of the potential *** are two characteristic lengths which determine the reflection *** dependence of the reflection probability on the width of the potential change shows distinct characters for potential wells and potential *** length of the dark soliton determines the sensitive width of potential wells,whereas for potential barriers,the decay length of the matter wave in the region of the barrier qualifies the sensitive width of the *** time evolution of the density profiles of the system during the reflection process is studied to disclose the different behaviors of matter waves in the region of the potential variation.

关键词： Bose-Einstein condensate dark soliton quantum reflection

Motion performance and impingement risk of total hip arthroplasty with a simulation module

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第9期14卷 849-854页

作者： Hai ZHOU Cheng-tao wang Wen-ting JI Xiang-sen ZENG Shu FANG dong-mei wang Institute of Biomedical Manufacturing and Life Quality Engineering School of Mechanical and Power Energy EngineeringShanghai Jiao Tong University Shanghai Fire Institute of Ministry of Public Security

The present study introduced a new motion analysis method for total hip arthroplasty (THA). A motion simulation module of THA was designed and developed, which can simulate the THA’s implantation condition and motion... 详细信息

关键词： THA Motion performance and impingement risk of total hip arthroplasty with a simulation module