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Comparative mammalian cell cytotoxicity of wastewater with elevated bromide and iodide after chlorination,chloramination, or ozonation

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Journal of Environmental Sciences 2017年第8期29卷 296-301页

作者： Shengkun dong Thanh H.nguyen Michael J.Plewa Department of Civil and Environmental Enoineering University of Illinois at Urbana-Champaign Urbana IL 61801 USA Department of Crop Sciences University of Illinois at Urbana-Champaign Urbana IL 61801 USA Safe Global Water Institute Uniuersity of Illinois at Urbana-Champaign Urbana IL 61801 USA

Recycling wastewater is becoming more common as communities around the world try to better control their water resources against an increased frequency of either prolonged droughts or intense flooding. For communities in coastal areas, wastewaters may contain elevated levels of bromide（Br^-） and iodide（I^-） from seawater intrusion or high mineral content of source waters. Disinfection of such wastewater is mandatory to prevent the spread of pathogens, however little is known about the toxicity of wastewater after disinfection in the presence of Br^-and I^-. In this study we compared the induction of chronic cytotoxicity in mammalian cells in samples of municipal secondary wastewater effluent amended with elevated levels of Br^-/I^-after disinfection by chlorine, chloramines or ozone to identify which disinfection process generated wastewater with the lowest level of adverse biological response. Chlorination increased mammalian cell cytotoxicity by 5times as compared to non-disinfected controls. Chloramination produced disinfected wastewater that expressed 6.3 times more cytotoxicity than the non-disinfected controls and was 1.3 times more cytotoxic than the chlorinated samples. Ozonation produced wastewater with cytotoxicity comparable to the non-disinfected controls and was at least 4times less cytotoxic than the chlorine disinfected wastewaters. These results indicate that compared to chlorination and chloramination, ozonation of wastewater with high Br^-/Ilevels yielded the lowest mammalian cell cytotoxicity, suggesting its potential as a more favorable method to disinfect wastewater with minimizing the biological toxicity in mind.

关键词： Cytotoxicity Ozonation Chlorination Chloramination Wastewater Bromide Iodide Disinfection

Tuberculosis Diagnosis and Visualization with a Large Vietnamese X-Ray Image Dataset

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Intelligent Automation & Soft Computing 2024年第2期39卷 281-299页

作者： nguyen Trong Vinh Lam Thanh Hien Ha Manh Toan Ngo Duc Vinh Do Nang Toan Faculty of Information Technology Lac Hong UniversityBien HoaDong Nai76120Vietnam Institute of Information Technology Vietnam Academy of Science and TechnologyHanoi10072Vietnam Faculty of Information Technology Hanoi University of IndustryHanoi11915Vietnam

Tuberculosis is a dangerous disease to human life,and we need a lot of attempts to stop and reverse ***,in theCOVID-19 pandemic,access to medical services for tuberculosis has become very *** late detection of tuberculosis could lead to danger to patient health,even *** one of the countries heavily affected by the COVID-19 pandemic,andmany residential areas as well as hospitals have to be isolated for a long *** demands a fast and effective tuberculosis diagnosis solution to deal with the difficulty of accessingmedical services,such as an automatic tuberculosis diagnosis *** our study,aiming to build that system,we were interested in the tuberculosis diagnosis problem from the chest X-ray images of Vietnamese *** chest X-ray image is an important data type to diagnose tuberculosis,and it has also received a lot of attention from deep learning *** paper proposed a novel method for tuberculosis diagnosis and visualization using the deeplearning approach with a large Vietnamese X-ray image *** detail,we designed our custom convolutional neural network for the X-ray image classification task and then analyzed the predicted result to provide visualization as a *** prove the performance of our network model,we conducted several experiments to compare it to another study and also to evaluate it with the dataset of this *** support the implementation,we built a specific annotation system for tuberculosis under the requirements of radiologists in the Vietnam National Lung Hospital.A large experiment dataset was also from this hospital,and most of this data was for training the convolutional neural network *** experiment results were evaluated regarding sensitivity,specificity,and *** achieved high scores with a training accuracy score of 0.99,and the testing specificity and sensitivity scores were over *** on the X-ray image classification result,we visualize pr

关键词： Tuberculosis classification Vietnamese chest X-ray deep learning

Ardisia gigantifolia ethanolic extract inhibits cell proliferation and targets cancer stem cells in gastric cancer

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Asian Pacific Journal of Tropical Biomedicine 2023年第6期13卷 258-267页

作者： Thi Thanh Huong Le Phu Hung nguyen van Phuong nguyen Thy Ngoc nguyen Faculty of Biotechnology TNU-University of SciencesThai NguyenVietnam Department of Life Science University of Science and Technology of HanoiVietnam Academy of Science and TechnologyHanoiVietnam

Objective:To evaluate the effects of ethanol extract from Ardisia gigantifolia leaves on cell proliferation and cancer stem cell(CSC)number in gastric ***:The inhibitory effect of Ardisia gigantifolia extract on the proliferation of MKN45 and MKN74 gastric cancer cells was assessed using 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide ***-adherent culture(3D)model was used to evaluate the effect of the extract on tumorsphere size and ***,the expression of CD44,ALDH,and p21 was determined by immunofluorescence *** cytometric analysis was performed to evaluate cell cycle arrest and the expression of gastric CSC markers CD44 and ***-time PCR analysis was also carried out to assess the effect of the extract on the expression of cell cycle-regulated ***:Ardisia gigantifolia extract effectively inhibited cell proliferation with an IC_(50)of 55.7μg/m L in MKN45 cells and 123.6μg/m L in MKN74 *** extract also arrested cell cycle in the G_(0)/G_(1)phase as well as significantly reduced the size and number of *** markedly increased expression of p21 was observed at both m RNA and protein levels in the extract-treated adherent cells and *** addition,Ardisia gigantifolia extract significantly reduced the number of CD44-and/or ALDH-expressing gastric ***:The development of gastric CSC can be inhibited by the ethanol extract of Ardisia gigantifolia.

关键词： Ardisia gigantifolia Gastric cancer Cancer stem cell markers CD44 ALDH

Discrete-time sliding mode control with power rate exponential reaching law of a pneumatic artificial muscle system

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Control Theory and Technology 2022年第4期20卷 514-524页

作者： Quy-Thinh Dao Trung-Kien Le Tri van-Anh nguyen Manh-Linh nguyen School of Electrical and Electronic Engineering Hanoi University of Science and TechnologyDai Co VietHanoi 11615Vietnam

This paper develops a discrete-time sliding mode controller with a power rate exponential reaching law approach to enhance the performance of a pneumatic artificial muscle system in both reaching time and chattering *** proposed method dynamically adapts to the variation of the switching function,which is based on an exponential term and a power rate term of the sliding ***,the controlled system can achieve high tracking performance while still obtain chattering-free ***,the effectiveness of the proposed method is validated through multiple experimental tests,focused on a dual pneumatic artificial muscle ***,experimental results show the effectiveness of the proposed approach in this paper.

关键词： Pneumatic artificial muscle Discrete-time sliding mode control Exponential reaching law Chattering

Antidiabetic and antioxidant activities of red seaweed Laurencia dendroidea

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Asian Pacific Journal of Tropical Biomedicine 2019年第12期9卷 501-509页

作者： The Han nguyen Thi Huyen nguyen van Minh nguyen Thi Lan Phuong nguyen Thi van Anh Tran Anh Duy Do Sang Moo Kim Faculty of Food Technology Nha Trang University02 Nguyen Dinh Chieu StreetNha Trang CityKhanh HoaVietnam Quality Control Department Institute of Vaccines and Medical BiologicalsNha Trang CityKhanh HoaVietnam Faculty of Pharmacy University of Medicine and Pharmacy of Ho Chi Minh City41 Dinh Tien Hoang StreetHo Chi Minh CityVietnam Research Department of Marine Conservation Research Institute for Marine Fisheries224 Le Lai StreetHai Phong CityVietnam Department of Marine Food Science and Technology Gangneung-Wonju National University7 Jukheon-gilGangneung 25457Republic of Korea

Objective:To investigate antidiabetic and antioxidant activities of the extract and fractions from Vietnamese red seaweed Laurencia ***:The seaweed Laurencia dendroidea was extracted by using microwave-assisted extraction method in 80%*** seaweed extract was then fractionated using different solvents(n-hexane,chloroform,ethyl acetate,butanol and water).These obtained fractions were evaluated forα-glucosidase inhibitory and antioxidant *** activities were tested using DPPH,nitric oxide radical scavenging and metal chelating *** enzyme inhibition mode was determined using Lineweaver-Burk *** acidic and thermal stabilities,the ethyl acetate fraction was treated at pH 2.0 and 100℃,*** residual inhibitory activity of the fraction was calculated based on the initial inhibitory *** in vivo antidiabetic activity,mice were divided into four groups,including normal control,diabetic control,diabetic mice treated with ethyl acetate fraction and diabetic mice treated with *** glucose level of treated mice during acute and prolonged treatments was *** evaluate the toxicity of the ethyl acetate fraction,the body weight changes and activities of liver function enzymes(aspartate transaminase,alanine transaminase and gammaglutamyl transferase)were carried ***:The extract of Laurencia dendroidea showed strongα-glucosidase inhibitory and DPPH radical scavenging *** concentrations affected bothα-glucosidase inhibitory and antioxidant activities.A 80%aqueous methanol was the suitable solvent for extraction of enzyme inhibitors and *** solvent fractions,ethyl acetate fraction had the highest inhibitory activities againstα-glucosidase with a mixed type of inhibition and the strongest antioxidant activities,and was stable under acidic and thermal *** ethyl acetate fraction treated diabetic mice significantly reduced blood glucose level compare

关键词： α-Glucosidase inhibitor Antidiabetic Antioxidant Red seaweeds Vietnam

SIMULATION MODEL OF TECHNOLOGICAL MINERAL DRESSING PROCESSES

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International Journal of Modeling, Simulation, and Scientific Computing 2012年第3期3卷 36-42页

作者： nguyen van CHI A.V.PETROV Department of Automated Systems Irkutsk State Technical University Lermontova 83 Irkutsk664074Russian Federation

The authors worked out a simulation model of technological mineral dressing processes,in which two simulations of technological mineral dressing processes methods are used:transformed structural graph method and method of separation *** first method makes it possible to simulate technological mineral dressing processes at the design stage in conditions of feedstock,equipment and control information *** second method is an effective instrument for operating plant simulation at the reengineering *** and economic efficiency evaluations of the mineral dressing plant are appended to the model.

关键词： Simulation mineral dressing structural graph separation characteristics reengineering efficiency

An Analytical Approach for Nonlinear Buckling Analysis of Torsionally Loaded Sandwich Carbon Nanotube Reinforced Cylindrical Shells with Auxetic Core

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Advances in Applied Mathematics and Mechanics 2023年第2期15卷 468-484页

作者： Dang Thuy dong nguyen Thi Phuong Vu Hoai Nam Le Ngoc Ly nguyen van Tien Vu Minh Duc Tran Quang Minh Vu Tho Hung nguyen Thi Huong Giang Faculty of Civil Engineering University of Transport TechnologyHanoi 100000Vietnam Graduate School of Advanced Science and Engineering Hiroshima University1-4-1 KagamiyamaHigashi-HiroshimaHiroshima 739-8527Japan Faculty of Fundamental Science for Engineering University of Transport TechnologyHanoi 100000Vietnam

The main aim of this paper is to present an analytical approach on the postbuckling for torsionally loaded sandwich carbon nanotube(CNT)reinforced cylindrical shells with the auxetic *** considered shells consist of three layers,external and internal CNT reinforced layers,and the auxetic lattice core made by isotropic *** homogenization model for honeycomb auxetic lattice core is utilized,and the equilibrium equations are formulated based on the nonlinear Donnell’s thin shell theory with von Karman geometrical *** three terms of deflection are considered,the Airy’s stress function and Galerkin’s method are utilized,the explicit expression of critical buckling of torsionally loaded shells and load-deflection expression of postbuckling states are *** effects of two carbon nanotube reinforced layers,the auxetic core layer,the volume fraction of carbon nanotube on the torsional buckling behavior are examined and remarked.

关键词： Nonlinear postbuckling carbon nanotube reinforced composite cylindrical shell torsion auxetic core

Sulphur vacancy defects engineered metal sulfides for amended photo(electro)catalytic water splitting: A review

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Journal of Materials Science & Technology 2023年第21期152卷 50-64页

作者： Kusum Sharma Abhinandan Kumar Tansir Ahamad Quyet van Le Pankaj Raizada Archana Singh Lan Huong nguyen Sourbh Thakur van-Huy nguyen Pardeep Singh School of Advanced Chemical Sciences Shoolini UniversitySolanHimachal Pradesh 173212India Department of Chemistry College of ScienceKing Saud UniversitySaudi Arabia Department of Materials Science and Engineering Korea University145AnamroSeongbuk-guSeoul 02841Republic of Korea Advanced Materials and Processes Research Institute Hoshangabad RoadBhopalMP 462026India Faculty of Biology and Environment Ho Chi Minh City University of Food Industry(HUFI)140 Le Trong Tan StreetTay Thanh WardTan Phu DistrictHo Chi Minh CityVietnam Department of Organic Chemistry Bioorganic Chemistry and BiotechnologySilesian University of TechnologyB.Krzywoustego 444-100 GliwicePoland Faculty of Allied Health Sciences Chettinad Hospital and Research InstituteChettinad Academy of Research and EducationKelambakkam-603103Tamil NaduIndia

Vacancy engineering in metal sulfides has garnered enormous attention from researchers because of their outstanding ability to modulate the optical and physiochemical properties of ***,in the case of sulfides,the catalytic activity is drastically hindered by the quick reassembly of excitons and the photocorrosion *** designing and generating S-vacancies in metal sulfides has emerged as a potential strategy for attaining adequate water splitting to generate H_(2) and O_(2) because of the simulta-neous improvement in the optoelectronic ***,developing efficient catalysts that manifest optimal photo(electro)catalytic performance for large-scale applicability remains ***,it is of utmost interest to explore the insightful features of creating S-vacancy and study their impact on catalytic *** review article aims to comprehensively highlight the roles of S-vacancy in sulfides for amended overall water-splitting *** photocatalytic features of S-vacancies modulated metal sulfides are deliberated,followed by various advanced synthetic and characterization techniques for effectual generation and identification of vacancy *** specific aspects of S-vacancies in refin-ing the optical absorption range charge carrier dynamics,and photoinduced surface chemical reactions are critically examined for overall water splitting ***,the vouchsafing outlooks and op-portunities confronting the defect-engineered(S-vacancy)metal sulfides-based photocatalysts have been summarized.

关键词： S-vacancy Photo(electro)catalysis Metal sulfides Water splitting Engineering Identification of S-vacancies

On the Laws of Large Numbers for Double Arrays of Independent Random Elements in Banach Spaces

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Acta Mathematica Sinica,English Series 2014年第8期30卷 1353-1364页

作者： Andrew ROSALSKY Le van THANH nguyen Thi THUY Department of Statistics University of FloridaGainesville Department of Mathematics Vinh University

For a double array of independent random elements {Vmn,m ≥ 1,n ≥ 1} in a real separable Banach space,conditions are provided under which the weak and strong laws of large numbers for the double sums mi=1 nj=1Vij,m ≥ 1,n ≥ 1 are *** the identically distributed and the nonidentically distributed cases are *** the main theorems,no assumptions are made concerning the geometry of the underlying Banach *** theorems are applied to obtain Kolmogorov,Brunk–Chung,and Marcinkiewicz–Zygmund type strong laws of large numbers for double sums in Rademacher type p（1 ≤ p ≤ 2） Banach spaces.

关键词： Real separable Banach space double array of independent random elements strong and weak laws of large numbers almost sure convergence convergence in probability Rademacher type p Banach space