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Energy Material Advances 2021年第1期2021卷 376-383页

作者： Wei Tang Jie Jian Gen Chen Wenjuan Bian Jiuling Yu Haiyan Wang Meng Zhou dong ding Hongmei Luo Department of Chemical and Materials Engineering New Mexico State UniversityLas CrucesNM 88003USA School of Materials Engineering Purdue UniversityWest LafayetteIN 47907USA Energy&Environment Science and Technology Idaho National LaboratoryIdaho FallsID 83415USA

Amorphous molybdenum disulfide(MoS_(2))is a promising electrochemical catalyst for hydrogen evolution reaction(HER)due to more active sites exposed on the surface compared to its crystalline *** this study,a novel fast three-minute one-pot method is proposed to prepare the single-wall carbon nanotube-(SWCNT-)supported amorphous MoS_(2) via a microwave heating *** to traditional hydro-or solvent thermal methods to prepare MoS_(2) which usually consume more than 10 hours,it is more promising for fast *** overpotential at 10 mA/cm2 of amorphous MoS_(2)@SWCNT is 178 mV,which is 99mV and 22mV lower than crystalline MoS_(2)@SWCNT and pure amorphous MoS_(2),*** running 1000 cycles of polarization,~2%increase in overpotential is observed,indicating its good *** enhanced performance results from the beneficial combination of the SWCNT substrate and the amorphous *** introduction of SWCNT increases catalyst conductivity and prevents MoS_(2) *** amorphous microstructures of MoS_(2) prepared by a microwave heating method lead to more Mo edges or active sites exposed.

关键词： stability. amorphous crystalline

Preliminary study on phonetic characteristics of patients with pulmonary nodules

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Journal of Integrative Medicine 2020年第6期18卷 499-504页

作者： Xue-yang Song Si-jing Wang Zhao-xia Xu Yi-ming Hao Lu Feng Xiao-dong ding Hui Gao Yi-qin Wang College of Basic Medicine Shanghai University of Traditional Chinese Medicine.Shanghai 201203China

Objective: Pulmonary nodules(PNs) are one of the imaging manifestations of early lung cancer screening,which should receive more attention. Traditional Chinese medicine believes that voice changes occur in patients with pulmonary diseases. The purpose of this study is to explore the differences in phonetic characteristics between patients with PNs and able-bodied ***: This study explores the phonetic characteristics of patients with PNs in order to provide a simpler and cheaper method for PN screening. It is a case-control study to explore the differences in phonetic characteristics between individuals with and without PNs. This study performed non-parametric statistics on acoustic parameters of vocalizations, collected from January 2017 to March 2018 in Shanghai,China, from these two groups;it explores the differences in third and fourth acoustic parameters between patients with PNs and a normal control group. At the same time, computed tomography(CT) scans,course of disease, combined disease and other risk factors of the patients were collected in the form of questionnaire. According to the grouping of risk factors, the phonetic characteristics of the patients with PNs were ***: This study was comprised of 200 patients with PNs, as confirmed by CT, and 86 healthy people that served as a control group. Among patients with PNs, 43% had ground glass opacity, 32% had nodules with a diameter ≥ 8 mm, 19% had a history of smoking and 31% had hyperlipidemia. Compared with the normal group, there were statistically significant differences in pitch, intensity and shimmer in patients with PNs. Among patients with PNs, patients with diameters ≥ 8 mm had a significantly higher third formant. There was a significant difference in intensity, fourth formant and harmonics-to-noise ratio(HNR)between smoking and non-smoking patients. Compared with non-hyperlipidemia patients, the pitch, jitter and shimmer of patients with PNs and hyperlipidemia were higher a

关键词： Pulmonary nodules Risk factors Phonetic characteristics Traditional Chinese medicin

Evolution of Palaeoenvironment of the South Yellow Sea Since the Last Deglaciation

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Journal of Ocean University of China 2020年第4期19卷 827-836页

作者： WANG Haoyin LI Guangxue ZHANG Yang LIU Yong LIU dongsheng ding dong XU Jishang MA Yanyan QIAO Lulu WANG Liyan LI Qian Key Laboratory of Submarine Sciences&Prospecting Techniques Ministry of EducationOcean University of ChinaQingdao 266100China College of Marine Geosciences Ocean University of ChinaQingdao 266100China

The sediments in core YS01 recovered from the South Yellow Sea mud deposit zone contain abundant benthic foraminifera,particularly shallow continental shelf species,but rare of planktonic *** benthic foraminifera are dominated by stenohaline cold shallow-water species and euryhaline brackish-water *** this paper,the palaeoenvironmental changes were discussed based on the grain-size compositions and benthic foraminiferal *** different benthic foraminiferal assemblages were discriminated by species analysis from the foraminiferal *** to AMS14C dating data in core YS01,we identified four main stages of marine environmental changes since the last deglaciation:a near-shore depositional stage(13.1–9.5 kyr B.P.),a transitional stage from near-shore deposition to shallow-sea deposition(9.5–5.6 kyr B.P.),a high sea level stage with shallow-sea deposition(5.6–2.9 kyr B.P.),and a stable shallow-sea depositional stage(2.9 kyr *** the present).

关键词： benthic foraminifera last deglaciation South Yellow Sea palaeoenvironmental change

Experimental animal models of pulmonary hypertension:Development and challenges

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Animal Models and Experimental Medicine 2022年第3期5卷 207-216页

作者： Xiao-Han Wu Jie-Ling Ma dong ding Yue-Jiao Ma Yun-Peng Wei Zhi-Cheng Jing Department of Cardiology State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Medical Science Research Center State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Pulmonary hypertension(PH) is clinically divided into 5 major types, characterized by elevation in pulmonary arterial pressure(PAP) and pulmonary vascular resistance(PVR), finally leading to right heart failure and death. The pathogenesis of this arteriopathy remains unclear, leaving it impossible to target pulmonary vascular remodeling and reverse the deterioration of right ventricular(RV) function. Different animal models have been designed to reflect the complex mechanistic origins and pathology of PH, roughly divided into 4 categories according to the modeling methods: noninvasive models in vivo, invasive models in vivo, gene editing models, and multi-means joint modeling. Though each model shares some molecular and pathological changes with different classes of human PH, in most cases the molecular etiology of human PH is poorly known. The appropriate use of classic and novel PH animal models is essential for the hunt of molecular targets to reverse severe phenotypes.

关键词： animal models BMPR2 chronic hypoxia monocrotaline pulmonary hypertension Sugen 5416

Research on Application of RFID Technology in the Agricultural Product Quality and Safety Traceability System

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International Journal of Technology Management 2015年第2期 108-110页

作者： Qijin dong & Fei ding Business Management Department Qingdao Vocational and Technical College of Hotel Management Qingdao Shandong266100China

Through the study of individual identification technology, the paper put forward the identification scheme for two-dimensional code ear tag ＋ RFID electronic tag, namely using Ministry of agriculture regulations two-dimensional code ear tag to identify individual animal in the breeding stage, and record the basic information and breeding, using the RFID electronic identification tag to record slaughter quarantine information; phase, and finally the ear tag code, RFID electronic tag and product number should be encode relatively to generate tracing code in the final agricultural products, realize the smooth flow of the information flow from the breeding stage to the final product. For fruits and vegetables, agricultural products are adopted the common identification for orchard （greenhouse） numbers units.

关键词： Traceability system RFID 2-D code Agricultural products

利用普通光学显微镜实现对微小物体三维体表参数的测量

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光学技术 2010年第3期36卷 328-332页

作者：陈丽雷亮马北河 ding dong 广东工业大学物理与光电工程学院广州510006 威廉港应用科技大学光学实验室德国威廉港26388

基于有较大的焦深的普通光学显微镜及3D成像软件,利用自制的可绕固定轴的升降平台及光纤辐照形态,根据视差原理构建了一个测量小型样品的三维表面参数的测试系统。以外形较复杂的医用牙科钻头为样品,研究了显微镜的放大倍数、用于构建... 详细信息

基于有较大的焦深的普通光学显微镜及3D成像软件,利用自制的可绕固定轴的升降平台及光纤辐照形态,根据视差原理构建了一个测量小型样品的三维表面参数的测试系统。以外形较复杂的医用牙科钻头为样品,研究了显微镜的放大倍数、用于构建三维图像的两幅相似图像的夹角与样品表面参数测量值之间的关系。通过与样品的标称值对比,实验中所用的毫米量级的样品,在合适的物镜组放大倍数及合适的夹角下,相对误差在5%范围内,表明所建立的测量系统可用于尺寸较小的样品表面参数的测量。

关键词：光学测量显微镜焦深表面参数 3D软件夹角

Sedimentary Characteristics of the Second Marine Layer During the Late Marine Isotope Stage 3 in Southern Yellow Sea and Their Response to the East Asian Monsoon

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Journal of Ocean University of China 2018年第5期17卷 1103-1113页

作者： ZHANG Yang LI Guangxue GUO Hongzhou LIU Yong WANG Haoyin XU Jishang ding dong QIAO Lulu MA Yanyan WANG Liyan LI Qian College of Marine Geosciences Ocean University of China Key Laboratory of Submarine Geoscience and Prospecting Techniques Ministry of Education Development Research Center China Geological Survey

We use the particle size of sediments in core YS01A to study the sedimentary environment of the mud deposit in the central South Yellow Sea of China during late Marine Isotope Stages 3 （MIS3; 40.5 kyr-31.3 kyr）. In addition, the East Asian Monsoon and its relationship with the North Atlantic Ocean climate change are discussed based on the sensitive grain-size calculation and the spectrum analysis. The results show that during late MIS3, the muddy area in the central South Yellow Sea experienced the evolution of coastal facies, shallow marine facies, coastal facies, and continental facies, with weak hydrodynamic conditions. Compared with other climate indicators, we found that there were many century to millennium-scale climate signals documented in the muddy area sediments in the central South Yellow Sea. According to our particle size results, three strong winter monsoon events occurred at 37.6kyr, 35.6kyr and 32.2kyr. The East Asian Winter Monsoon records in core YS01A are consistent with the Greenland ice core and the Hulu cave stalagmite 8180. The millennial and centennial scale cycles, which are 55 yr, 72 yr, 115 yr, 262 yr respectively, correspond to solar activity cycles, while the 1049 yr and 2941 yr cycles correspond to the Dansgaard-Oeschger cycles. These cycles indicate that the paleoclimate evolution of the area was controlled by the solar activities, with the high-latitude driving thermohaline circulation as the main energy conveyor belt, followed by the sea-air-land amplification of the winter monsoon variation in the central Yellow Sea in the late MIS3.

关键词： sedimentary environment central South Yellow Sea East Asian Monsoon sensitive grade calculation thermohaline circulation

An Effective On-line Surface Particles Inspection Instrument for Large Aperture Optical Element

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International Journal of Automation and computing 2017年第4期14卷 420-431页

作者： Wen-dong ding Zheng-Tao Zhang Da-Peng Zhang De Xu Hai-Bing Lv Xin-Xiang Miao Guo-Rui Zhou Hao Liu Research Center of Precision Sensing and Control Institute of Automation Chinese Academy of Sciences School of Computer and Control Engineering University of Chinese Academy of Sciences Laser Fusion Research Center China Academy of Engineering Physics

Surface particles growing in large aperture optical element （LAOE） have significant impact on LAOE＇s stable operation. It is a challenge for the online system to inspect the particles with long working distance, enough precision and high efficiency because of the system constraints. In this paper, an effective and portable inspection instrument is designed based on dark-field imaging principle. A Nikon lens and an industrial high definition （HD） camera are selected to construct the vision system to inspect particles of microns size spreading over hundreds of millimeters. Using two motors and other mechanical structure, the system can realize auto-focus and image rectification functions. The line light sources are installed on both sides of the LAOE in a sealed box while the vision system is portable and working outside the box. An adaptive binarization method is proposed to process the captured dark-field image. The distribution of particles on the LAOE＇s surface is investigated. Because of the high resolution of the captured image, the SSE2 instructions optimization method is used to reduce the time cost of the algorithm. Experiments show that the instrument can inspect LAOE effectively and accurately.

关键词： Dark-field imaging image rectification adaptive binarization particle inspection large aperture optical elements(LAOE).

Accelerated Cutaneous Wound Healing Using an Injectable Teicoplanin-loaded PLGA-PEG-PLGA Thermogel Dressing

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Chinese Journal of Polymer Science 2019年第6期37卷 548-559页

作者： Wei-Ke Xu Jing-Yu Tang Zhang Yuan Cai-Yun Cai Xiao-Bin Chen Shu-Quan Cui Peng Liu Lin Yu Kai-Yong Cai Jian-dong ding State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular Science Fudan University Key Laboratory of Biorheological Science and Technology Ministry of Education College of Bioengineering Chongqing University

Bacterial infection is a very troublesome issue in wound treatment, which stimulates exudate formation and severely delays the healing process. Herein, a thermogelling dressing system composed of two triblock copolymers of poly(D,L-lactic acid-co-glycolic acid)-b-poly(ethylene glycol)-b-poly(D,L-lactic acid-co-glycolic acid)(PLGA-PEG-PLGA) with different block lengths was developed to deliver teicoplanin(TPN), a glycopeptide antibiotic, for cutaneous wound repair. The TPN-loaded thermogel was a free-flowing sol at room temperature and formed a semi-solid gel at physiological temperature. In vitro studies demonstrated that the TPN-loaded thermogel system exhibited desired tissue adhesiveness and realized the sustained release of TPN in a fast-followed-slow manner for over three weeks. Furthermore, a full-thickness excision wound model in Sprague-Dawley(SD) rats was constructed to assess the efficacy of TPNloaded thermogel formulation. Gross and histopathologic observations implied that treatment with the thermogel formulation reduced inflammation response, promoted disposition of collagen, enhanced angiogenesis, and accelerated wound closure and maturity of SD *** combination of the bioactivity of TPN and the acidic nature of the thermogel matrix was responsible for such an enhanced wound healing process. Consequently, the TPN-loaded PLGA-PEG-PLGA thermogel is a good candidate of wound dressing for full-thickness excision wound healing.

关键词： Wound dressing PLGA-PEG-PLGA thermogel Anti-infection Teicoplanin Sustained release

The role of primary cilia in mechanical transmission of osteocyte based on a 3D finite element model

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Medicine in Novel Technology and Devices 2024年第1期21卷 31-38页

作者： Zhuang Han dong ding Yu-bo Fan Xin-tong Wu Xiao Yang Lian-wen Sun Key Laboratory of Biomechanics and Mechanobiology(Beihang University)Ministry of Education Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijing100083China Department of Cardiology State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

The primary cilium,as a mechanical receptor of osteocytes,participates in the regulation of osteocyte ***,how the length of osteocyte primary cilia changes with fluid shear stress(FSS)are unclear,and how the mechanical transmission within osteocytes altered by primary cilia is not well understood ***,the ciliary length changes of osteocyte under 15dyn/cm2 of FSS were experimentally detected,and then 3D finite element models of osteocyte primary cilia containing the basal body and axoneme were *** results showed that(1)The ciliary length of the CON group,FSS 1h,and FSS 6h were 3.71±1.34μm,3.79±1.04μm,and 1.24±0.73μm respectively,indicating the different durations of FSS might lead to the adaptive changes of cilium *** calculations showed(2)when the ciliary length became shorter with the ciliary angle stayed the same,the deformation and stress of the cell membrane and membrane skeleton was ***,the deformation and stress of the cilia membrane,basal body,the rotation angles of basal body were decreased,and those of cytoplasm,cytoskeleton,actin cortex and nucleus were also decreased;(3)With the decrease of the ciliary angle,the deformation and stress of the cilia membrane,basal body,as well as the rotation angles of basal body were *** of the cytoplasm,cytoskeleton,actin cortex,and nucleus were also increased except the cell membrane and membrane *** calculation results suggested the length and angle of the primary cilia,the deformation and stress of intracellular structures in osteocyte were altered with ciliary basal body,indicated the connection between the basal body and cytoskeleton may be a key factor that affected the mechanical transport in osteocytes across the cell *** finally promoted the adaptive change of ciliary length under FSS.

关键词： Primary cilia Osteocyte model Finite element analysis Mechanotransduction