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散货海港泊位分配及装卸设备调度协同优化研究

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散货海港泊位分配及装卸设备调度协同优化研究

作者： dolores g. perez Orozco 上海交通大学

学位级别：硕士

大宗货物需求的日益增长趋势促使包括散货海港在内的港口提高效率。2015年7月新加坡港的石油吞吐量创了新高并导致了港区的拥堵,中国和澳大利亚的港口由于煤炭进出口需求的增大面临着同样的问题。因此,有必要通过开发数学优化模型以提... 详细信息

大宗货物需求的日益增长趋势促使包括散货海港在内的港口提高效率。2015年7月新加坡港的石油吞吐量创了新高并导致了港区的拥堵,中国和澳大利亚的港口由于煤炭进出口需求的增大面临着同样的问题。因此,有必要通过开发数学优化模型以提高港口作业的效率。本论文研究目的是通过开发泊位分配及装卸设备调度协同优化模型以提高散货海港的作业效率。针对离散泊位布局,本文既考虑船舶在码头的停靠位置(泊位分配),又根据货物的类型做出装卸设备调度的决策,以最小化船舶在港靠泊时间。所构建的数学优化模型考虑了不同装卸设备(如输送带、管道、抓斗起重机和水泥设施)的具体作业效率。基于实际港口的案例研究表明,该模型合理分配了专用泊位、专用装卸设备,显著减少了在港靠泊时间和拥堵。本文同时针对港口可持续性和韧性的概念开展了系统性的文献综述,为港口建设具备可持续性的系统总结了经验和建议。

关键词：散货海港可持续性泊位分配航运物流

Radiation protection for the interventional cardiologist:Practical approach and innovations

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World Journal of Cardiology 2022年第1期14卷 1-12页

作者： Alejandro gutierrez-Barrios dolores Cañadas-Pruaño Inmaculada Noval-Morillas Livia gheorghe Ricardo Zayas-Rueda german Calle-perez Department of Cardiology Hospital Puerta del MarCadiz 11009Spain

Use of ionizing radiation during cardiac catheterization interventions adversely impacts both the patients and medical *** recent years,radiation dose in cardiac catheterization interventions has become a topic of increasing interest in interventional cardiology and there is a strong interest in reducing radiation exposure during the *** review presents the current status of radiation protection in the cardiac catheterization laboratory and summarizes a practical approach for radiation dose management for minimizing radiation *** review also presents recent innovations that have clinical potential for reducing radiation during cardiac interventions.

关键词： Radiation Cardiac catheterization Quality improvement Cathlab Ionizing radiation

Heritage risk index:A multi-criteria decision-making tool to prioritize municipal historic preservation projects

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Frontiers of Architectural Research 2020年第2期9卷 403-418页

作者： Jonathan Ruiz-Jaramillo Carmen Munoz-gonzalez Maria dolores Joyanes-Diaz Eduardo Jimenez-Morales Jose Manuel Lopez-Osorio Roberto Barrios-perez Carlos Rosa-Jimenez Department of Art and Architecture School of ArchitectureUniversidad de MalagaMalaga 29071Spain

The current pressure on the built historical heritage requires a global evaluation to develop strategies for its preservation.A combined vision of the state of conservation of architectural heritage is essential to highlight the vulnerabilities of the structure from which harmonized measures can be proposed for its *** study proposes a multi-criteria analysis methodology that considers a qualitative and quantitative approach to organize the global conservation state of heritage buildings hierarchically.A global index can be determined on the basis of the generation of an interoperable data matrix by defining a set of indicators to assess different components of a *** index describes the risk with respect to the stability,safety,and habitability of the *** methodology aims to achieve the state of the building in an integral way by obtaining a simple and objective index that enables efficient comparison among different *** application of this methodology to a historic area allows creating a hierarchical map of risk to stablish priorities for intervention and enable a sustainable and critical management and planning over the actions of maintenance,conservation,and *** this way,a holistic vision of the complex reality of built heritage and the urban landscape is obtained to identify critical areas of priority intervention.

关键词： Historic city State of conservation Risk index Intervention priority Architectural heritage

Recurrent anal fistulae:Limited surgery supported by stem cells

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World Journal of gastroenterology 2015年第11期21卷 3330-3336页

作者： Damian garcia-Olmo Hector guadalajara Ines Rubio-perez Maria dolores Herreros Paloma de-la-Quintana Mariano garcia-Arranz Hospital Fundación Jimenez Díaz Colorectal Surgery Unit University Hospital Fundación Jiménez Díaz Colorectal Surgery Unit La Paz University Hospital Cell Therapy Laboratory University Hospital Fundación Jiménez Díaz

AIM:To study the results of stem-cell therapy under a Compassionate-use Program for patients with recurrent anal ***:Under controlled circumstances,and approved by European and Spanish laws,a Compassionate-use Program allows the use of stem-cell therapy for patients with very complex anal *** had previously undergone multiple surgical interventions that had failed to resolve the fistulae,and presented symptomatic *** intervention consisted of limited surgery(with closure of the internal opening),followed by local implant of stem cells in the fistula-tract *** expanded adipose-derived stem cells were the main cell type selected for *** first evaluation was performed on the 8th postoperative week;outcome was classified as response or partial *** one year after the intervention confirmed if complete healing of the fistula was ***:Ten patients(8 male)with highly recurrent and complex fistulae were treated(mean age:49years,range:28-76 years).Seven cases were nonCrohn’s fistulae,and three were Crohn’s-associated *** surgical attempts ranged from 3to *** patients presented with preoperative incontinence(Wexner scores of 12 and 13 points).After the intervention,six patients showed clinical response on the 8th postoperative week,with a complete cessation of suppuration from the *** patients presented a partial response,with an evident decrease in suppuration.A year later,six patients(60%)remained healed,with complete reepithelization of the external *** Wexner Scores were 0 in six *** two patients with previous incontinence improved their scores from12 to 8 points and from 13 to 5 *** adverse reactions or complications related to stem-cell therapy were reported during the study ***:Stem cells are safe and useful for treating anal *** can be achieved in severe cases,sparing fecal incontinence risk,and impr

关键词： Adipose-derived stem cells Cell therapy Compassion

Effectiveness and safety of first-generation protease inhibitors in clinical practice:Hepatitis C virus patients with advanced fibrosis

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World Journal of gastroenterology 2015年第30期21卷 9163-9174页

作者： Javier Salmeron Carmen Vinaixa Ruben Berenguer Juan Manuel Pascasio Juan Jose Sanchez Ruano Miguel angel Serra Ana gila Moises Diago Manuel Romero-gomez Jose Maria Navarro Milagros Testillano Conrado Fernandez dolores Espinosa Isabel Carmona Jose Antonio Pons Francisco Jorquera Francisco Javier Rodriguez Ramon perez Jose Luis Montero Rafael granados Miguel Fernandez Ana Belen Martin Paloma Munoz de Rueda Rosa Quiles CIBERehd Instituto de Salud Carlos Ⅲ28029 MadridSpain Unit for Clinical Management of Digestive Diseases Complejo Hospitalario Universitario de Granada Instituto de Investigacion Biosanitaria de granada University Hospital Politecnico La Fe Unit for Clinical Management of Digestive Diseases University Hospital Virgen Del Rocio Hospital Toledo University Clinic Hospital of Valencia University general Hospital of Valencia Unit for Clinical Management of Digestive Diseases University Hospital Nuestra Senora de Valme Department of gastroenterology and Hepatology Agencia Sanitaria Costa del Sol University Hospital Cruces gastroenterology Unit University Hospital Fundacion Alcorcon University Hospital Virgen Macarena University Hospital Virgen de la Arrixaca Hospital of Leon University general Hospital Reina Sofia Department gastroenterology and Hepatology University Hospital Central de Asturias University Hospital Reina Sofia University Hospital De gran Canaria Dr. Negrin Hospital San Pedro de Alcantara

AIM:To evaluates the effectiveness and safety of the first generation,NS3/4A protease inhibitors(PIs) in clinical practice against chronic C virus,especially in patients with advanced fibrosis. METHODS:Prospective study and non-experimental analysis of a multicentre cohort of 38 Spanish hospitals that includes patients with chronic hepatitis C genotype 1,treatment-na?ve(TN) or treatment-experienced(TE),who underwent triple therapy with the first generation NS3/4A protease inhibitors,boceprevir(BOC) and telaprevir(TVR),in combination with pegylated interferon and ribavirin. The patients were treatment in routine practice settings. Data on the study population and on adverse clinical and virologic effects were compiled during the treatment period and during follow ***:One thousand and fifty seven patients were included,405(38%) were treated with BOC and 652(62%) with TVR. Of this total,30%(n = 319) were TN and the remaining were TE:28%(n = 298) relapsers,12%(n = 123) partial responders(PR),25%(n = 260) null-responders(NR) and for 5%(n = 57) with prior response unknown. The rate of sustained virologic response(SVR) by intention-to-treatment(ITT) was greater in those treated with TVR(65%) than in those treated with BOC(52%)(P gnificant differences. By degree of fibrosis,56% of patients were F4 and the highest SVR rates were recorded in the non-F4 patients,both TN and TE. In the analysis by groups,the TN patients treated with TVR by ITT showed a higher SVR(P = 0.005). However,by m ITT there were no significant differences between BOC and TVR. In the multivariate analysis by m ITT,the significant SVR factors were relapsers,IL28 B CC and non-F4; the type of treatment(BOC or TVR) was not significant. The lowest SVR values were presented by the F4-NR patients,treated with BOC(46%) or with TVR(45%). 28% of the patients interrupted the treatment,mainly by non-viral response(51%):this outcome was

关键词： Hepatitis C Boceprevir Telaprevir First-generation protease inhibitors Advanced fibrosis