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Antioxidant and antimicrobial activities of selected medicinal plants from Algeria

Journal of Coastal Life Medicine 2014年第6期 478-483页

作者： Krimat Soumia dob tahar Lamari Lynda Boumeridja Saida Chelghoum Chabane Metidji Hafidha Laboratoire de Molécules Bio-Actives et Valorisation de la Biomasse ENS koubaAlgeria Laboratoire de Biologie des Systèmes Microbiens ENSKoubaAlgeria Departement of Natural sciences ENSKoubaAlgeria Laboratoire de chromatographie facultéde chimieUSTHBAlgiersAlgeria

Objective:To evaluate the antioxidant and antimicrobial activity of methanolic extract extracts of selected Algerian medicinal ***:Antioxidant activity of extracts was evaluated in terms of radical scavenging potential(2,2-diphenyl-1-picrylhydrazyl)and β-carotene bleaching *** phenolic contents and flavonoid contents were also *** activity of these plants was examined against Bacillus subtilis,Staphylococcus aureus,Escherichia coli,Pseudomonas aeruginosa and Candida ***:The values of IC_(50) ranged from 4.30μg/mL to 486.6μg/mL for the DPPH method,while total antioxidant activity using β-carotene/linoleic acid bleaching assay ranged from 17.03%to 86.13%.It was found that Pistacia lentiscus showed the highest antioxidant capacities using DPPH assay(IC_(50)=4.30μg/mL),while Populus trimula,Origanum glandulosum,Centaurea calcitrapa,Sysimbrium officinalis and Rhamnus alaternus showed the highest percent of total antioxidant activity in β-carotene/linoleic acid bleaching *** phenolic and flavonoid contents ranged from 3.96 to 259.65 mg GAE/g extract and from 1.13 to 26.84 mg QE/g extract,*** most interesting antimicrobial activity was obtained from Sysimbrium officinalis,Rhamnus alaternus,Origanum glandulosum,Cupressus sempervirens,Pinus halipensis and Centaurea ***:The results indicated that the plants tested may be potential sources for isolation of natural antioxidant and antimicrobial compounds.

关键词： Antioxidant activity DPPH Antimicrobial activity Disc diffusion method Total phenolic content Total flavonoid content

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Chemical composition,antioxidant and antimicrobial activities of the essential oil of Santolina chamaecyparissus *** Algeria

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Journal of Coastal Life Medicine 2015年第3期 220-227页

作者： Nouasri Ahmed dob tahar Krimats Soumia Dahmane Dahmane Toumi Mohamed Lynda Lamari Chelgoume Chabane Racheme Farida Bioactive Molecules Laboratory and Valorisation of Biomass Ecole Normale SupérieureB.P.9216500 KoubaAlgersAlgeria Microbiology Laboratory Ecole Normale SupérieureB.P.9216500 KoubaAlgersAlgeria Chromatography Laboratory USTHBAlgersAlgeria Microbiology Laboratory CRD Saidal El MohamdiaAlgesAlgeria

Objective:To investigate the chemical composition,antioxidant and antimicrobial activities of essential oil of Santolina chamaecyparissus *** in ***:The chemical composition of hydrodistilled essential oil from flowering aerial parts has been analyzed by gas chromatograph and gas chromatograph-mass spectrometer *** antioxidant activities conducted by 2,2-diphenyl-1-picrylhydrazyl scavenging test andβ-carotene bleaching *** antimicrobial activity was realised by agar disc diffusion method and cornell medical index was determined by agar dilution method in solid ***:About 36 components accounting more than 82%of the total oil were *** monoterpenes was the main fraction(54.66%)and was represented by artemisia ketone(40.33%)as major component of this *** other major constituents were(Z)-thujone(9.82%),(2Z,6E)-farnesol(7.30%)and limonene(6.87%)and concerning antiradical scavenging test(2,2-diphenyl-1-picrylhydrazyl)had demonstrated a weak activity obtained with an EC_(50) of(43.01±8.04)and moderate activity for β-carotene bleaching test(47.00±3.13)at 120 *** the other hand,this oil was found effective against all tested strains except Pseudomonas aeruginosa and Aspergillus *** activity was ranging from 10 mm to 24 mm with the lowest minimum inhibitory concentration value between under 0.070μg/mL to upper 9μg/***:The results provided evidence that the studied plant might indeed be potential sources of natural antioxidant and antimicrobial agents.

关键词： Chemical composition Antioxidant and antimicrobial activities Artemisia ketone Essential oil Santolina chamaecyparissus L

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