检索结果-南通市图书馆

Anti-inflammatory effects of Solanum procumbens on a low dose complete Freund's adjuvant-induced arthritis rat model

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2023年第5期13卷 214-221页

作者： xuan-hai do Trong Nghia Nguyen thanh Chung Dang Thi thanh Mai Nguyen Trung Nhan Nguyen Van Nhat Truong do Huu tho Le xuan hai Nguyen Hoang Phu Dang Giang-Linh Nguyen Dinh-Khanh Hoang Van-Quan Le Van-Mao Can Department of Practical and Experimental Surgery Vietnam Military Medical UniversityHanoi 10000Vietnam Department of Reconstructive and Microsurgery Craniofacial and Reconstructive Surgery CentreMilitary Central Hospital 108Hanoi 10000Vietnam Department of Anatomic Pathology Military Hospital 103Vietnam Military Medical UniversityHanoi 10000Vietnam Faculty of Chemistry University of ScienceVietnam National University Ho Chi Minh CityHo Chi Minh City 70000Vietnam Faculty of Medicine University of Medicine and PharmacyVietnam National UniversityHanoi 10000Vietnam Department of Ultrasound Imaging Diagnostics CentreMilitary Hospital 103Vietnam Military Medical UniversityHanoi 10000Vietnam Department of Functional Diagnostics Military Hospital 103Vietnam Military Medical UniversityHanoi 10000Vietnam Department of Pathophysiology Vietnam Military Medical UniversityHanoi 10000Vietnam

Objective:To investigate the anti-inflammatory and analgesic effects of Solanum procumbens on complete Freund’s adjuvantinduced arthritis rat ***:We isolated and identified five compounds in the ethanolsoluble Solanum procumbens extract(SP)with anti-inflammatory effects,including ursolic acid,β-sitosterol,hexadecanoic acid,cisvaccenic acid,and vanillic ***,we investigated the anti-inflammatory effects of SP on rheumatoid arthritis symptoms,including paw volumes,local temperatures,withdrawal latency,and mechanical withdrawal threshold at the hind paw and white blood cell(WBC)number from complete Freund’s adjuvant-induced arthritis rat ***:We have successfully established a complete Freund’s adjuvant-induced arthritis rat model at a low dose(1 mg/mL).SP extract significantly reduced paw volumes(Pdose of 300 mg/kg significantly decreased WBC ***:SP extract could be a potential medication candidate with anti-inflammatory effects for arthritis,but it requires further investigation into the mechanism of the SP and its effectiveness on other models as well as clinical trials.

关键词： Solanum procumbens Arthritis Anti-inflammation Complete Freund's adjuvant Rats

Granulocyte colony-stimulating factor reduces biliary fibrosis and ductular reaction in a mouse model of chronic cholestasis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Liver Research 2023年第1期7卷 90-98页

作者： Trinh Van Le thanh Minh Dang Huy Quang do Ai-xuan Le Holterman Hong-Thuy Phan-Thi thong Tan tran Nhung hai Truong Laboratory of Stem Cell Research and Application University of Science-VNUHCMHo Chi Minh CityVietnam Vietnam National University Ho Chi Minh CityVietnam Department of Pediatrics and Surgery University of Illinois College of MedicineChicagoILUSA Faculty of Biology and Biotechnology University of Science-VNUHCMHo Chi Minh CityVietnam

Background:Biliary atresia is a rare congenital bile duct disease that is the leading cause of liver fibrosis in *** colony-stimulating factor(GCSF)is a potential therapy for hepatocellular diseases,but data on GCSF for cholestatic conditions remain *** and methods:The current study examines the role of GCSF in improving bile duct obstruction in *** doses were administered:10.0 mg/kg/day and 61.5 mg/kg/day,which is the animal equivalent dose of 5.0 mg/kg in *** days(D7)after bile duct ligation(BDL),Swiss mice were treated with phosphate buffered saline or GCSF for 5 *** intrahepatic adaptive response of BDL mice was evaluated on postsurgical days D12,D19,and ***:Treatment with 61.5 mg/kg of GCSF resulted in a significant increase in circulating leukocytes and neutrophils on *** of liver injury,as shown by reduced aspartate aminotransferase levels,increased albumin levels and survival rate,as well as reduced intrahepatic inflammation and hepatic myeloperoxidase expression,downregulated ductular proliferation,periportal fibroblast activation,and fibrosis,enhanced expressions of hepatocyte growth factor,peroxisome proliferator-activated receptoralpha,and ki67,and suppressed expression of cleaved caspase-3 protein,was noted after treatment with 61.5 mg/kg of ***,GCSF treatment was associated with an increased number of intrahepatic cd3-Sca1tc-Kitt bone marrow cells.

关键词： Bile duct ligation(BDL) Biliary fibrosis Ductular reaction Granulocyte colony-stimulating factor(GCSF) Hepatic stellate cell(HSC)

Investigation of Polymorphisms in Coding Region of OsHKT1in Relation to Salinity in Rice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rice science 2016年第6期23卷 334-338页

作者： pham quynh-hoa tran xuan-an nguyen thi-nha-trang tran thi-thuy-anh hoang hai-yen nguyen thi-hong-van tang thi-hanh do thi-phuc Faculty of Biology VNU University of ScienceHanoi334 Nguyen TraiThanh XuanHanoiVietnam Faculty of Agronomy Vietnam National University of AgricultureNgo Xuan Quang StreetTrau QuyGia LamHanoiVietnam

Rice （Oryza sativa） is sensitive to salinity, but the salt tolerance level differs among cultivars,which might result from natural variations in the genes that are responsible for salt tolerance. High-affinitypotassium transporter （HKTs） has been proven to be involved in salt tolerance in plants. Therefore, wescreened for natural nucleotide polymorphism in the coding sequence of OsHKT1, which encodes the HKTprotein in eight Vietnamese rice cultivars differing in salt tolerance level. In total, seven nucleotidesubstitutions in coding sequence of OsHKT1 were found, including two non-synonymous and five synonymoussubstitutions. Further analysis revealed that these two non-synonymous nucleotide substitutions （G50Tand T1209A） caused changes in amino acids （Gly17Val and Asp403Glu） at signal peptide and the loop ofthe sixth transmembrane domain, respectively. To assess the potential effect of these substitutions on theprotein function, the 3D structure of HKT protein variants was modelled by using PHYRE2 webserver. Theresults showed that no difference was observed when compared those predicted 3D structure of HKTprotein variants with each other. In addition, the codon bias of synonymous substitutions cannot clearlyshow correlation with salt tolerance level. It might be interesting to further investigate the functional roles ofdetected non-synonymous substitutions as it might correlate to salt tolerance in rice.

关键词： polymorphism salt stress OsHKT1 gene rice

Hybrid model to optimize object-based land cover classification by meta-heuristic algorithm:an example for supporting urban management in Ha Noi,Viet Nam

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

International Journal of Digital Earth 2019年第10期12卷 1118-1132页

作者： Quang-thanh Bui Manh Pham Van Nguyen Thi Thuy Hang Quoc-Huy Nguyen Nguyen xuan Linh Pham Minh hai tran Anh Tuan Pham Van Cu Center for Applied Research in Remote sensing and GIS(CARGIS) VNU University of ScienceHa NoiViet Nam VNU University of Science Ha NoiViet Nam Vietnam Institute of Geodesy and Cartography Ha NoiViet Nam Ministry of Education and Training Ha NoiViet Nam

This study proposed a novel object-based hybrid classification model named GMNN that combines Grasshopper Optimization Algorithm(GOA)and the multiple-class Neural network(MNN)for urban pattern detection in Hanoi,*** bands of SPOT 7 image and derivable NDVI,NDWI were used to generate image segments with associated attributes by PCI Geomatics *** segments were classified into four urban surface types(namely water,impervious surface,vegetation and bare soil)by the proposed ***,three training and validation datasets of different sizes were used to verify the robustness of this *** all tests,the overall accuracies of the classification were approximately 87%,and the Area under Receiver Operating Characteristic curves for each land cover type was ***,the performance of this model was examined by comparing several statistical indicators with common benchmark *** results showed that GMNN out-performed established methods in all comparable *** results suggested that our hybrid model was successfully deployed in the study area and could be used as an alternative classification method for urban land cover *** a broader sense,classification methods will be enriched with the active and fast-growing contribution of metaheuristic algorithms.

关键词： Urban remote sensing object-based classification neural network grasshopper optimization algorithm

Assessing and Forecasting Saline Intrusion in theVietnamese Mekong Delta Under the Impact of Upstreamflow and Sea Level Rise

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Science and Engineering(B) 2019年第5期8卷 174-185页

作者： tran xuan hai Vu Van Nghi Vu Hoang Hung do Ngoc Tuan Dang thanh Lam Can Thu Van Institute for Science and Technology Innovation Ho Chi Minh City 700000Vietnam University of Science Vietnam National UniversityHo Chi Minh City 700000Vietnam Thuyloi University Ha No 100000Vietnam Southern Institute for Water Resources Planning Ho Chi Minh City 700000Vietnam Ho Chi Minh City University of Natural Resources and Environment Ho Chi Minh City 700000Vietnam

Saline intrusion is a hot issue and has always been of concern in the VMD(Vietnamese Mekong Delta),especially in the context of many changes of impact factors such as upstream flows and SLR(Sea Levels Rise).Vulnerability to changes in the upstream flows and SLR ismust-have reasons for updated and interpreted *** information is used for exploiting of soil and water *** 11 model was successfully applied to assess the saline *** study provided the picture of the saline intrusion in the dry season from January to May in the VMD in the existing situation(2015 and 2016)and the future(2030 and 2050)under the impact of flow at Kratie in various frequencies of 18%,50%and 85%based on the time series of 2001-2016,and SLR according to RCP(Representative Concentration Pathway)4.5 scenario of MONRE(Ministry of Natural Resources and Environment)of Vietnam issued in *** results show that in the year 2015 the ASI(Saline Intrusion Area)in the VMD was relatively low due to moderate tidal level and high Kratie discharge(P=18%).The scenario like the situation in 2016 and in the future ASI increased significantly compared to the 2015 baseline scenario which shows that the VMD is very vulnerable to saline *** on multivariate regression analysis,the study also presented the formulas for the relationship between the ASI of 0.25 g/L,2.5 g/L and 4.0 g/L thresholds and the impact factors such as the average discharge at Kratie and the maximum daily tidal level in East Coast during the dry season from January to *** an adjusted R2 at 0.913-0.974,these formulas are believed to be reliable for predicting ASIs based on the Kratie flow and the East Coast tidal level.

关键词： Saline intrusion sea level rise upstream flow VMD

越南东北部Cat Ba岛泥盆系-石炭系过渡层的初探(英文)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

地球学报 2012年第S1期33卷 38-38页

作者： Toshifumi KOMATSU Reishi TAKASHIMA TA Hoa PHUONG tran Huyen DANG Duc Phong NGUYEN Huu Hung NGUYEN Satoru KATO Kento HIRATA Takumi MAEKAWA Graduate School of Science and Technology Kumamoto UniversityKumamoto 806-8555Japan The Center for Academic Resources and Archives Tohoku University Museum Tohoku UniversityAramaki Aza Aoba 6-3Aoba-kuSendai 980-8578Japan College of Sciences Vietnam National University334 Nguyen TraiThanh XuanHanoi Vietnam Vietnam Institute of Geosciences and Mineral Resources(VIGMR) HanoiVietnam Vietnam National Museum of Nature(VNMN) HanoiVietnam

The Pho Han Formation is exposed on southern Cat Ba Island,hai Phong Province in northeastern Vietnam,and intercalates the Devonian and Carboniferous(D-C) boundary(Ta and doan,2007;Komatsu et al.,2012).The D-C boundar... 详细信息

关键词： D-C boundary Conodont δ13C Cat Ba Island Vietnam