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Assessing and reducing risks from historical gold mine tailings in Nova Scotia, Canada

Chinese j.urnal Of Geochemistry 2006年第B8期25卷 32-33页

作者： Michael B. parsons paul K. Smith Terry A. Goodwin Gwendy E.M. Hall j.anne B. percival Rita Mroz Kenneth G, Doe Kok-leng Tay Vince-p. palace Geological Survey of Canada （Atlantic） P.O. Box 1006 Dartmouth NS Canada B2Y4A2 Nova Scotia Department of Natural Resources 1701 Hollis St. Halifax NS Canada B3J 2T9 Geological Survey of Canada 601 Booth St. Ottawa ON Canada K1A 0E8 Environment Canada 45 Alderney Dr. Dartmouth NS Canada B2Y 2N6 Environment Canada P.O. Box 23005 Moncton NB Canada E1A 6S8 Fisheries and Oceans Canada 501 University Cr Winnipeg MB Canada R3T 2N6

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呕吐导致整个虹膜自无缝线的白内障切口脱出

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世界核心医学期刊文摘（眼科学分册） 2005年第8期1卷 17-18页

作者： Slettedal j.K. Bragad'ottir R. 司冰心 Department of Ophthalmology Ullevaal University Hospital Kirkeveien 166 N-0407 Oslo Norway

purpose: To present a case of isolated total iris expulsion through a self-se aling cataract incision 2 weeks postoperatively due to vomiting. Methods: Ophtha lmological examination included visual acuity assessment, tonometry, slit-lamp examination, fundus ophthalmoscopy and ultrasound examination. Results: A 65-ye ar-old woman experienced sudden visual loss during an episode of vigorous vomit ing 2 weeks after uncomplicated phacoemulsification cataract surgery with a sutu reless corneal incision. Clinical examination showed a dense anterior chamber ha emor rhage. When the blood had cleared, isolated total aniridia was seen. Conclusio ns: This is the first reported case of aniridia after cataract surgery due to vo miting.

关键词：白内障超声乳化白内障手术眼内压眼科检查前房出血首例报道发作过程眼底镜剧烈呕吐周前

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受控导线断线时输电铁塔的实测动态特性

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电力建设 2007年第5期28卷 93-96页

作者： M CLARK D j.RICHARDS D CLUTTERBUCK 何鹏(翻译) 马明(编校) 英国国家电网股份有限公司英国南安普敦大学土木与环境工程学院不详

英国在1条退役的输电铁塔上进行了断线事件的现场模拟测试,研究了传递到输电铁塔塔腿的负载分布、负载传递速率。在土工离心机中进行了相似的物理模型研究,给出了负载传递速率和承载系数(ns)的关系。

关键词：架空线路铁塔浅塔腿上拔阻力物理模型荷载率的影响

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内瑟顿综合征:报道2例患有葡萄球菌烫伤样皮肤综合征的台湾双胞胎及其SpINK5位点的点突变

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世界核心医学期刊文摘（皮肤病学分册） 2005年第6期1卷 51-52页

作者： Richard G. Lee j.Y.-Y. 潘敏 Department of Dermatology School of Medicine National Cheng Kung University 138 Sheng-Li Road TainanChina Taiwan

Netherton syndrome (ns) is a severe autosomal recessive ichthyosis. It is characterized by congenital ichthyosiform erythroderma, trichorrhexis invaginata, ichthyosis linearis circumflexa, atopic diathesis and frequent bacterial infections. pathogenic mutations in SpINKS have recently been identified in ns. SpINKS encodes lymphoepithelial Kazal-type-related inhibitor (LEKTI), a new type of serine protease inhibitor involved in the regulation of skin barrier formation and immunity. We report two Taiwan Residents brothers with ns. The patients had typical manifestations of ns with an atopic diathesis and recurrent staphylococcal infections, including staphylococcal scalded skin syndrome (SSSS) since birth. Horny layers were obtained by skin surface biopsy for electron microscopy from lesional skin of both patients and from normal controls. All 33 exons and flanking intron boundaries of SpINKS were amplified for direct sequencing. The ultrastructure of the stratum corneum (SC) was characterized by premature degradation of corneo desmosomes (CDs) with separation of corneocytes. A homozygous 2260A→ T (K754X) mutation of SpINK5 was found in both patients. Staphylococcal exfoliative toxin A (ETA) is a serine protease capable of cleaving desmoglein 1, an important adhesive molecule of CDs, and can cause separation of the SC, resulting in SSSS. The premature degradation of CDs found in our patients may be attributable to insufficient LEKTI, and possibly also to colonization/infection of ETA-producing Stophylococcus aureus. Mechanisms involved in the pathogenesis of the skin barrier defect in ns are proposed. Further study is needed to prove this hypothesis.

关键词： SpINK5 鱼鳞病样红皮病迂回线状鱼鳞病点突变过敏性体质角质层分离葡萄球菌感染常染色体隐性直接测序套叠

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ST段抬高型心肌梗死患者行直接经皮冠状动脉介入术前依替巴肽的急诊早期使用:TITAN(急性心肌梗死患者中至应用依替巴肽治疗时间)-TIMI34试验的结果

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世界核心医学期刊文摘（心脏病学分册） 2007年第2期3卷 29-30页

作者： GibsonC.M. Kirtane A.j. Murphy S.A. 苏畅 TIMI Study Group Cardiovascular Division Brigham and Women's Hospital Boston MA United States.Dr.

背景:ST段抬高型心肌梗死(STEMI)患者行直接经皮冠状动脉介入(pCI)术前心外膜血流的早期恢复常伴有较好的临床预后。方法:设想,与在心脏导管室(CCL)行诊断性血管造影后使用血小板糖蛋白IIb/IIIa受体拮抗剂依替巴肽相比较,行pCI术前在急... 详细信息

背景:ST段抬高型心肌梗死(STEMI)患者行直接经皮冠状动脉介入(pCI)术前心外膜血流的早期恢复常伴有较好的临床预后。方法:设想,与在心脏导管室(CCL)行诊断性血管造影后使用血小板糖蛋白IIb/IIIa受体拮抗剂依替巴肽相比较,行pCI术前在急诊科(ED)早期使用依替巴肽可获得更好的心外膜血流和心肌灌注。343例STEMI患者被随机分为两组,分别于ED早期(n=180)或CCL(n=163)应用依替巴肽。

关键词：依替巴肽 ST段抬高 TIMI34 TITAN 血小板糖蛋白心肌灌注急诊科受体拮抗剂血管造影

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偶发轻度认知功能障碍预后与病例定义的关系

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世界核心医学期刊文摘（神经病学分册） 2005年第11期1卷 44-45页

作者： Fisk j.D. Rockwood K. 王孝文 Capital District Health Authority 1421-5955 Veterans’Memorial Lane Halifax NS B3H 2E1 Canada

Definitions of mild cognitive impairment (MCI) vary, yielding conflicting results. For example, case definitions affect prevalence but not outcomes in prevalent cases. Our obj.ctive was to determine whether variation in case definitions affects outcomes in incident cases of MCI. The 5 year risks of death, institutionalisation, and dementia were evaluated in clinically examined incident MCI cases in the Canadian Study of Health and Aging. The definition of MCI was varied so as to include or relax combinations of diagnostic features from consensus criteria. Relative risks (RR) of each adverse outcome were highest in MCI case definitions that required subj.ctive memory complaints (for example, RR of dementia=26.4-38.7). Although each MCI definition conferred an increased risk of dementia, for each case definition 20-30%of survivors had no cognitive impairment at follow up. In this population based study, MCI represented a transitional state, but was heterogeneous, with substantial proportions recovering, regardless of how MCI was defined. Factors associated with recovery and non-progression in MCI require elucidation.

关键词：病例定义记忆障碍相对风险诊断标准诊断特征常因本项过渡状态

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肥厚型心肌病患者心电图形态与表型表现及临床预后的关系

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世界核心医学期刊文摘（心脏病学分册） 2006年第1期2卷 34-34页

作者： Montgomery j. V. Harris K. M. Casey S. A. B.j. Maron 王亭忠 Dr. Hypertrophic Cardiomyopathy Center Minneapolis Heart Institute Foundation Minneapolis MN United States

Twelve-lead electrocardiography, a traditional component in evaluations of patients with hypertrophic cardiomyopathy (HC), is often regarded as a marker for the magnitude of left ventricular(LV) hypertrophy, which in turn has been linked to sudden death risk. To determine whether electrocardiographic(ECG) patterns have clinical utility by accurately reflecting phenotypic expression or predicting clinical outcome, voltages and patterns were compared with LV wall thicknesses assessed by echocardiography and with clinical outcomes in 448 consecutive patients with HC. Significant but relatively weak correlations were evident between maximum LV wall thickness and ECG voltage: r=0.295(ppppatients with extreme LV hypertrophy(LV wall thickness ≥30 mm), only 24(44%) showed greatly increased ECG voltage≥30 mm in any lead. Of 102 patients with outflow gradients≥30 mm Hg at rest, only 43(42%) had ECG voltage ≥30 mm in any lead. Normal ECG results were uncommonly associated with HC-related death(1 of 40 patients, 2.5%) but had similar prevalence in surviving patients(17 of 376 patients, 4.5%; p.ns). In conclusion, in HC, 12-lead ECG voltages are not a reliable clinical marker for the magnitude of LV hypertrophy or outflow obstruction. Diverse ECG patterns, consistent with heterogenous expression of this disease, did not predict HC-related death. Scalar electrocardiography has selective but limited power in routine clinical assessments of patients with HC.

关键词：肥厚型心肌病临床预后心电图形态患者表型超声心动图检测室壁厚度导联心电肥厚程度

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Directional coherent light via intensity-induced sideband emission

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Light(Science & Applications) 2016年第1期5卷 33-38页

作者： Andrew j.Traverso Chris O’Brien Brett H Hokr j.nathan V Thompson Luqi Yuan Charles W Ballmann Anatoly A Svidzinsky Georgi I petrov Marlan O Scully Vladislav V Yakovlev Texas A&M University College StationTX 77843USA princeton University PrincetonNJ 08544USA Baylor University WacoTX 76798USA

We introduce a unique technique for generating directional coherent emissions that could be utilized to create coherent sources in a wide range of frequencies from the extreme ultraviolet(XUV)to the deep *** is accomplished without population inversion by pumping a two-level system with a far-detuned strong optical field that induces the splitting of the two-level system.A nonlinear process of four-wave mixing then occurs across the split system,driving coherent emission at sidebands both redand blue-detuned from the pump frequency,and propagates both forward and backward along the pump beam *** observed this phenomenon in dense rubidium vapor along both the D_(1) and D_(2) *** sideband emission exhibits a short pulse duration(o1 ns)with threshold-like behavior dependent on both the pump intensity and Rb vapor *** technique offers a new capability for manipulating the emission frequency simply through intensity-induced atomic modulation that can be scaled to most frequency regimes using various atomic/molecular ensembles and pump energies.

关键词： coherent emission collective coherence four-wave mixing

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98Sr两准粒子带研究

98Sr两准粒子带研究

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第十次全国核结构研讨会暨第六次全国核结构专题讨论会

作者：李明亮朱胜江 j.H.Hamilton A.V.Ramayya j.K.Hwang 车兴来禹英男 I.Y.Lee j.O.Rasmussen 清华大学物理系 Department of physics Vanderbilt UniversityNashvilleTennessee 37235USA Lawrence Berkeley National Laboratory BerkeleyCalifornia 94720USA

通过对252Cf的自发裂变产生的瞬发γ谱的分析,对丰中子核98Sr的集体转动带进行了研究.扩展了建立在1838keV能级上的K=3的转动带.新发现了一个建立在2535keV能级上的K=6的转动带.通过分析,这两个带的带头组态都是v9/2[404]⊕v3/2[411],... 详细信息

通过对252Cf的自发裂变产生的瞬发γ谱的分析,对丰中子核98Sr的集体转动带进行了研究.扩展了建立在1838keV能级上的K=3的转动带.新发现了一个建立在2535keV能级上的K=6的转动带.通过分析,这两个带的带头组态都是v9/2[404]⊕v3/2[411],分别满足关系Ω=|Ω1-Ω2|和Ω=|Ω1+Ω2|.用延迟符合方法测量,我们得到K=3和K=6的两个带的半衰期分别是13±3ns和4.5±1.0ns.

关键词：自发裂变准粒子带半衰期延迟符合

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A pan-serotype dengue virus inhibitor targeting the ns3-ns4B interaction

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四川生理科学杂志 2021年第8期43卷 1459-1459页

作者： Suzanne j.F Kaptein 不详

Dengue virus causes approximately 96 million symptomatic infections annually,manifesting as dengue fever or occasionally as severe dengue1,*** are no antiviral agents available to prevent or treat ***,we describe a highly potent dengue virus inhibitor(j.j.A07)that exerts nanomolar to picomolar activity against a panel of 21 clinical isolates that represent the natural genetic diversity of known genotypes and *** molecule has a high barrier to resistance and prevents the formation of the viral replication complex by blocking the interaction between two viral proteins(ns3 and ns4B),thus revealing a previously undescribed mechanism of antiviral action.

关键词： ns4B interaction annually

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