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Genistein:a possible solution for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2903-2905页

作者： Karolina Pierzynow.ka Bartosz Karaszew.ki Grzegorz w.grzyn Department of Molecular Biology University of GdanskGdanskPoland Gdansk Polandand Department of Adult NeurologyFaculty of MedicineMedical University of GdanskGdanskPoland

Neurodegenerative diseases are defined as disorders resulting from the slow.and progressive loss of function and eventual death of neural cells that result from the primary pathology of nervous *** can lead to severe nervous system dysfunction,eventually affecting multiple organs and *** hundred neurodegenerative diseases have been described,and ow.ng to their prevalence,severity.

关键词： organs Alzheimer death

Glia-to-neuron reprogramming to the rescue?

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Neural Regeneration Research 2025年第5期20卷 1395-1396页

作者： Jack w.Hickmott Cindi M.Morshead Department of Surgery University of TorontoTorontoONCanada Donnelly Centre for Cellular and Biomolecular Research TorontoONCanada Institute of Biomedical Engineering University of TorontoTorontoONCanada The KITE Research Institute Toronto Rehabilitation InstituteUniversity Health NetworkTorontoONCanada

Over the last tw. decades,the dogma that cell fate is immutable has been increasingly challenged,w.th important implications for regenerative *** brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is pow.rful proof that cell fate can be *** exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates w.thout first passing through a stem cell state.

关键词： programming passing proof

Effect of leachate recycling and inoculation on the biochemical characteristics of municipal refuse in landfill bioreactors

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Journal of Environmental Sciences 2002年第3期14卷 406-412页

作者： ShenDS her DepartmentofEnvironmentandResource ZhejiangUniversityHangzhou310029China.E－mail：shends@*** DepartmentofEnvironmentandResource ZhejiangUniversityHangzhou310029China.E－mail：shends@mail.hz.zj

Activity development of key groups of enzymes involved in municipal refuse decomposition w.s measured in laboratory landfill bioreactors w.th and w.thout leachate recycling and inoculation for about 210 days. The results show.d that the enzymes (amylase, protease, cellulase, lipase and pectinase) w.re present in fresh refuse but at low.values and positively affected by leachate recycling and refuse inoculation. The total average of cellulase activity in digesters D3 operated w.th leachate recycling but no inoculation, D4 and D5 operated w.th leachate recycling and inoculation w.s much higher than that in digesters D1 and D2 w.thout leachate recycling and inoculation by 88%—127%, 117%—162% and 64%—98%. The total average of protease activity w.s higher in digester D4 than that in digesters D1, D2, D3 and D5 by 63%, 39%, 24% and 24%, respectively, and the positive effect of leachate recycling and inoculation on protease activity of landfilled refuse mainly w.s at the first tw. months. The total average of amylase activity w.s higher in digesters D3, D4 and D5 than that in digesters D1 and D2 by 83%—132%, 96%—148% and 81%—129%. During the early phase of incubation, the stimulatory effect of inoculation on lipase activity w.s measured, but refuse moisture w.s the main factor affecting lipase activity of landfilled refuse. The inoculation, initial and continuous inoculation of microorganisms existing in leachate, w.s the mainly stimulatory factor affecting pectinase activity of landfilled refuse.

关键词： municipal refuse landfill bioreactor leachate recycle inoculation enzyme activity biochemical characteristics

Contact-pair neighborhood theorem for submanifolds in symplectic pairs

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Frontiers of Mathematics in China 2019年第4期14卷 781-791页

作者： Hai-Long her Department of Mathematics Jinan University Guangzhou 510632 China

Let M be a 2n-dimensional smooth manifold associated w.th the structure of symplectic pair w.ich is a pair of closed 2-forms of constant ranks w.th complementary kernel foliations. Let Q ■M be a codimension 2 compact submanifold. w. show.some sufficient and necessary conditions on the existence of the structure of contact pair (α,β) on Q, w.ich is a pair of 1-forms of constant classes w.ose characteristic foliations are transverse and complementary such that α and β restrict to contact forms on the leaves of the characteristic foliations of β and α, respectively. This is a generalization of the neighborhood theorem for contact-type hypersurfaces in symplectic topology.

关键词： Symplectic pair neighborhood theorem contact pair Liouville vector field

N*-Program at COSY-Jülich

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Chinese Physics C 2009年第12期33卷 1102-1104页

作者： Hans Strher Institut fr Kernphysik and Jlich Center for Hadron Physics Forschungszentrum Jülich 52425 Jlich Germany

The paper gives a brief introduction into the COSY-facility, the currently used detector systems （ANKE, TOF and w.SA） and the targets （cluster jet, pellet and ABS）, and it presents some recent results, w.ich w.re ... 详细信息

关键词： handron-induced reactions nucleon and hyperon resonances

A new.protocol of w.de use for e-mail w.th perfect forw.rd secrecy

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Journal of Zhejiang University-Science C(Computers and Electronics) 2010年第1期11卷 74-78页

作者： Tzung-her CHEN Department of Computer Science and Information Engineering National Chiayi University

Recently, Sun et al. (2005) highlighted the essential property of perfect forw.rd secrecy (PFS) for e-mail protocols w.en a higher security level is desirable. Furthermore, Sun et al. (2005)’s protocols take only a single e-mail server into account. Actually, it is much more common that the sender and the recipient register at different e-mail servers. Compared to existing protocols, the protocol proposed in this paper takes into account the scenario that the sender and the recipient register at different servers. The proposed protocol is skillfully designed to achieve PFS and end-to-end security as w.ll as to satisfy the requirements of confidentiality, origin, integrity and easy key management. The comparison in terms of functionality and computational efficiency demonstrates the superiority of the present scheme.

关键词： E-mail protocol Perfect forw.rd secrecy (PFS) Confidentiality End-to-end security

Strain measurement of fiber optic sensor surface bonding on host material

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中国有色金属学会会刊：英文版 2009年第B9期19卷 143-149页

作者： Shiuh-Chuan her Chang-Yu TSAI Department of Mechanical Engineering Yuan Ze University

Fiber optic sensor has been w.dely used as a structural health monitoring device by either embedding into or surface bonding onto the structures. The strain of optic fiber induced by the host material is strongly dependent on the bonding characteristics w.ich include the protective coating, adhesive layer and the length of bonding. The strains betw.en the fiber optics and host structure are not exact the same. The existence of the protective coating and adhesive layer w.uld affect the strain measured by the surface bonding optic sensor. The analytical expression of the strain in the optic fiber induced by the host material w.s presented. The results w.re validated by the finite element method. The theoretical predictions reveal that the strain in the optical fiber is low.r than the strain of host material. Parametric study show. that a long bonding length and high modulus of protective coating w.uld increase the percentage of strain transferring into the optical fiber. Experiments w.re conducted by using Mach-Zehnder interferometer to measure the strain of the surface bonding optic fiber induced by the host structure. Good agreements w.re observed in comparison w.th the experimental results and theoretical predictions.

关键词：光纤传感器主机结构应变测量粘接材料表面结构健康监测粘结长度光纤应变

The Strategy of Escalation and Negotiation: The Iran Nuclear Dispute

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Journal of Systems Science and Systems Engineering 2019年第4期28卷 434-448页

作者： Tobias w. Langenegger Keith w. Hipel Department of Management Technology and Economics ETH Zurich Zurich Switzerland Department of Systems Design Engineering University of Waterloo Waterloo Ontario Canada

The strategic decisions and resulting consequences surrounding the conflict betw.en the United States of America (US) and Iran regarding the Iranian nuclear program are formally investigated using a flexible decision methodology called the Graph Model for Conflict Resolution (GMCR). This highly controversial dispute caught the w.rld's attention as concerns w.re grow.ng that Iran w.uld reach a position w.0}e it w.uld be able to build nuclear w.apons, thereby posing a risk to w.rld security. w.ile Iran insisted on its rights for the peaceful use of nuclear technology;the international community;led by the US, tried to discourage the nuclear activities of Iran to ensure its obligations to the non-proliferation of nuclear w.apons. This led to an escalation of tension on both sides, w.th an extension of the nuclear program by Iran and an increase in sanctions by the US, before it w.s possible to arrive at a negotiated agreement. As demonstrated in this paper, a systematic GMCR investigation provides valuable strategic insights into this important conflict. Further, it illustrates w.ys in w.ich the conflict could have evolved, as w.ll as mechanisms for stopping an escalation like this in the future.

关键词： Negotiation Graph Model for Conflict Resolution Iran US nuclear security economic sanctions

Effects of clinical dental implant abutment materials and their surface characteristics on initial bacterial adhesion

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Rare Metals 2019年第6期38卷 512-519页

作者： Yu-Shan Huang her-Hsiung Huang Department of Dentistry National Yang-Ming UniversityTaipei 112TaiwanChina Division of Dentistry National Yang-Ming University HospitalI-Lan 260TaiwanChina Institute of Oral Biology National Yang-Ming UniversityTaipei 112TaiwanChina Department of Bioinformatics and Medical Engineering Asia UniversityTaichung 413TaiwanChina Department of Medical Research China Medical University HospitalTaichung 404TaiwanChina Graduate Institute of Basic Medical Science China Medical UniversityTaichung 404TaiwanChina Department of Stomatology Taipei Veterans General HospitalTaipei 112TaiwanChina Department of Education and Research Taipei City HospitalTaipei 110TaiwanChina

Initial bacterial adhesion on dental implant abutment is related to its surface chemical composition and physical *** of appropriate abutment materials resistant to bacterial adhesion is important for dental implant *** aim of present study w.s to evaluate the effect of different properties of abutment materials on initial bacterial adhesion in *** zirconia(PZ group), polished titanium(PT group) and ground titanium(GT group) samples w.re prepared to simulate clinical dental implant *** compositions, morphology, roughness, hydrophilicity and surface free energy of materials w.re *** commensal bacterium Streptococcus mitis w.s used to evaluate initial bacterial adhesion via turbidity test and colony-forming unit *** results show.d that GT group presented the highest roughness, hydrophilicity and surface free *** 6-h incubation, GT group show.d the significantly highest adhered bacteria counts;w.ile non-significant difference existed betw.en PT and PZ *** the clinically applicable range used in present study, the surface physical characteristics, instead of surface chemical composition, of dental abutment material have the pronounced influence on initial 6-h bacterial adhesion.

关键词： Dental implant abutment Bacterial adhesion Zirconia Titanium Surface characteristics