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Validity,reliability,and psychometric properties of a computerized,cognitive assessment test(Cognivue^®)Validity,reliability,and psychometric properties of a computerized,cognitive assessment test(Cognivue^®)

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World Journal of Psychiatry 2020年第1期10卷 1-11页

作者： diego cahn-hidalgo Paul W Estes Reina Benabou Internal Medicine of Brighton RochesterNY 14623United States Cognivue Inc. VictorNY 14564United States

BACKGROUND Cognitive issues such as Alzheimer’s disease and other dementias confer a substantial negative *** relating to sensitivity,subjectivity,and inherent bias can limit the usefulness of many traditional methods of assessing cognitive *** To determine cut-off scores for classification of cognitive impairment,and assess Cognivue®safety and efficacy in a large validation *** Adults(age 55-95 years)at risk for age-related cognitive decline or dementia were invited via posters and email to participate in two cohort studies conducted at various outpatient clinics and assisted-and independent-living *** the cut-off score determination study(n=92),optimization analyses by positive percent agreement(PPA)and negative percent agreement(NPA),and by accuracy and error bias were *** the clinical validation study(n=401),regression,rank linear regression,and factor analyses were *** in the clinical validation study also completed other neuropsychological *** For the cut-off score determination study,92 participants completed *** University Mental Status(SLUMS,reference standard)and Cognivue^®*** showed that SLUMS cut-off scores of26(no impairment)corresponded to Cognivue^®scores of 54.5(NPA=0.92;PPA=0.64)and 78.5(NPA=0.5;PPA=0.79),***,conservatively,Cognivue^®scores of 55-64 corresponded to impairment,and 74-79 to no *** the clinical validation study,401 participants completed≥1 testing session,and 358 completed 2 sessions 1-2 wk ***^®classification scores were validated,demonstrating good agreement with SLUMS scores(weightedκ0.57;95%CI:0.50-0.63).Reliability analyses showed similar scores across repeated testing for Cognivue^®(R2=0.81;r=0.90)and SLUMS(R2=0.67;r=0.82).Psychometric validity of Cognivue^®was demonstrated *** neuropsychological *** were most closely correlated with measures of verbal pro

关键词： Cognitive screening test Dementia Memory Motor control Perceptualprocessing Visual salience

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5DGWO-GAN:A Novel Five-Dimensional Gray Wolf Optimizer for Generative Adversarial Network-Enabled Intrusion Detection in IoT Systems

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Computers, Materials & Continua 2025年第1期82卷 881-911页

作者： Sarvenaz Sadat Khatami Mehrdad Shoeibi Anita Ershadi Oskouei diego Martín Maral Keramat Dashliboroun Department of Data Science Engineering University of HoustonHoustonTX 77204USA The WPI Business School Worcester Polytechnic InstituteWorcesterMA 01609USA School of Systems and Enterprises Stevens Institute of TechnologyHobokenNJ 07030USA Department of Computer Science Escuela de Ingeniería Informática de SegoviaUniversidad de ValladolidSegovia40005Spain Ernest G.Welch School of Art&Design Georgia State UniversityAtlantaGA 30303USA

The Internet of Things(IoT)is integral to modern infrastructure,enabling connectivity among a wide range of devices from home automation to industrial control *** the exponential increase in data generated by these interconnected devices,robust anomaly detection mechanisms are *** detection in this dynamic environment necessitates methods that can accurately distinguish between normal and anomalous behavior by learning intricate *** paper presents a novel approach utilizing generative adversarial networks(GANs)for anomaly detection in IoT ***,optimizing GANs involves tuning hyper-parameters such as learning rate,batch size,and optimization algorithms,which can be challenging due to the non-convex nature of GAN loss *** address this,we propose a five-dimensional Gray wolf optimizer(5DGWO)to optimize GAN *** 5DGWO introduces two new types of wolves:gamma(γ)for improved exploitation and convergence,and theta(θ)for enhanced exploration and escaping local *** proposed system framework comprises four key stages:1)preprocessing,2)generative model training,3)autoencoder(AE)training,and 4)predictive model *** generative models are utilized to assist the AE training,and the final predictive models(including convolutional neural network(CNN),deep belief network(DBN),recurrent neural network(RNN),random forest(RF),and extreme gradient boosting(XGBoost))are trained using the generated data and AE-encoded *** evaluated the system on three benchmark datasets:NSL-KDD,UNSW-NB15,and *** conducted on diverse IoT datasets show that our method outperforms existing anomaly detection strategies and significantly reduces false *** 5DGWO-GAN-CNNAE exhibits superior performance in various metrics,including accuracy,recall,precision,root mean square error(RMSE),and convergence *** proposed 5DGWO-GAN-CNNAE achieved the lowest RMSE values across the NSL-KDD,UNSW-NB15,and

关键词： Internet of things intrusion detection generative adversarial networks five-dimensional binary gray wolf optimizer deep learning

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Development of Aircraft Maintenance Glossaries in Higher Education:Exploring Methodological Paths to Corpus-Driven Analysis of Key Keywords

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中国科技术语 2025年第1期27卷 83-93页

作者： Malila PRADO Daniela TERENZI diego BRITO BNU-HKBU United International College Zhuhai 519087 Federal Institute of Education Science and Technology of São PauloSão Carlos 13.565-820

This paper presents a project aimed at developing a trilingual visual dictionary for aircraft maintenance professionals and *** project addresses the growing demand for accurate communication and technical terminology in the aviation industry,particularly in Brazil and *** study employs a corpus-driven approach,analyzing a large corpus of aircraft maintenance manuals to extract key technical terms and their *** specialized subcorpora and a comparative analysis,this paper demonstrates challenges and solutions into the identification of high-frequency keywords and explores their contextual use in aviation documentation,emphasizing the need for clear and accurate technical *** incorporating these findings into a trilingual visual dictionary,the project aims to enhance the understanding and usage of aviation terminology.

关键词： aircraft maintenance corpus keyword extraction

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Environmental analysis of innovative sustainable composites with potential use in aviation sector -A life cycle assessment review

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Science China(Technological Sciences) 2017年第9期60卷 1301-1317页

作者： BACHMANN Jens hidalgo Carme RICOUT Stephanie Deutsches Zentrum fiir Lufi- und Raumfahrt e. V. (German Aerospace Centre) Institute of Composite Structures and Adaptive Systems-Department of Multifunctional Materials Lilienthalplatz 7 38108 Braunsehweig Germany Leitat Technological Center C/Innovacio 2 08225 Terrassa Spain Airbus Group Innovations Fuels and Environment 12 rue Pasteur 92152 Suresnes France

The forecast of growing air transport in the upcoming decades faces the challenge of an increasing environmental *** industry is working on promising technologies to mitigate this environmental *** design is a strong lever to lower the fuel consumption and,consequently,with it the emissions of *** performance composites are a key technology to help achieve these aims thanks to their favourable combination of mechanical properties and low weight in primary ***,mainly synthetic materials such as petrol based carbon fibres and epoxy resins are used nowadays to produce composite in *** materials like bio-based fibres and resin systems offer potential environmental ***,they have not found their way into aviation,*** reasons are reduced mechanical properties and,especially for the use of natural fibres,their *** of these shortcomings are under *** the application of bio-based and recycled materials in certain areas of the aircraft could be possible in the *** examples for applications are furnishings and secondary *** motivation for this paper is to give an overview of potential environmental properties by using such eco-materials in *** cycle assessment(LCA) is a tool to calculate environmental impacts during all life stages of a *** main focus is laid on the bio-fibres flax and ramie,recycled carbon fibres and bio-based thermoset resin *** an overview of environmental aspects of existing composite materials used in aviation is ***,a lack of LCA results for the substitution of synthetic materials by bio-based/recycled composite materials in aviation applications has been ***,available information from other transport areas,such as automotive,has been *** detailed LCA data for eco-composite materials and technologies to improve their properties is import

关键词： aviation composite natural fibre recycled carbon fibre bio-resin cabin interior secondary structure,fife cycle assessment (LCA)

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Numerical Approach of a Coupled Pressure-Saturation Model Describing Oil-Water Flow in Porous Media

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Communications on Applied Mathematics and Computation 2023年第2期5卷 946-964页

作者： Paula Luna Arturo hidalgo ISIS Neutron and Muon Source Rutherford Appleton LaboratoryDidcot OX110QXUK Departamento de Ingeniería Geológica y Minera Escuela Técnica Superior de Ingenieros de Minas y EnergíaCenter for Computational SimulationUniversidad Politécnica de MadridRíos Rosas2128003 MadridSpain

Two-phase flow in porous media is a very active field of research,due to its important applications in groundwater pollution,CO_(2)sequestration,or oil and gas production from petroleum reservoirs,just to name a few of *** flow equations,which make use of Darcy's law,for describing the movement of two immiscible fluids in a porous medium,are among the most relevant mathematical models in reservoir *** work aims to solve a fractional flow model formed by an elliptic equation,representing the spatial distribution of the pressure,and a hyperbolic equation describing the space-time evolution of water *** numerical solution of the elliptic part is obtained using a finite-element(FE)scheme,while the hyperbolic equation is solved by means of two dif-ferent numerical approaches,both in the finite-volume(FV)*** is based on a monotonic upstream-centered scheme for conservation laws(MUSCL)-Hancock scheme,whereas the other makes use of a weighted essentially non-oscillatory(ENO)*** both cases,a first-order centered(FORCE)-αnumerical scheme is applied for inter-cell flux reconstruction,which constitutes a new contribution in the field of fractional flow models describing oil-water movement.A relevant feature of this work is the study of the effect of the parameterαon the numerical solution of the models *** also show that,in the FORCE-αmethod,when the parameterαincreases,the errors diminish and the order of accuracy is more properly attained,as verified using a manufactured solution technique.

关键词： Two-phase flow Reservoir simulation Porous media FORCE-α Finite volume

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Effect of Heat Loss on Laminar Flamelet Species Concentration

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Journal of Thermal Science 2016年第5期25卷 418-423页

作者： Marco Boccanera diego Lentini Dipartimento di Ingegneria Meccanica e Aerospaziale Sapienza Università di Roma

The effects of heat loss on the structure of laminar flamelets,which are the constitutive elements of turbulent flames under the most common operating conditions,are investigated for typical aeronautical gas-turbine operating conditions at *** magnitude of heat loss is quantified via the "enthalpy defect" measured with respect to an adiabatic flame.A procedure to generate laminar flamelets with an assigned enthalpy defect at the boundaries is devised and applied to nonpremixed propane/air flames,as propane reproduces the essential features of higher hydrocarbon *** is found,contrary to commonly held beliefs,that the enthalpy defect has a significant effect on the concentration not only of minor species,but also of main reaction *** effects are found in general to be more pronounced for fuel-rich *** impact is anticipated on the formation rate of nitric *** effects of scalar dissipation rate are also discussed.

关键词： Turbulent Combustion Heat Transfer Laminar Flamelets Hydrocarbon Combustion Aeroengines Gas Turbines

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Implicit large eddy simulation of unsteady cloud cavitation around a plane-convex hydrofoil

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Journal of Hydrodynamics 2015年第6期27卷 815-823页

作者： hidalgo Victor 罗先武 ESCALER Xavier 季斌 AGUINAGA Alvaro Beijing Key Laboratory of CO2 Utilization and Reduction Technology Tsinghua University CDIF Universitat Politècnica de Catalunya School of Power and Mechanical Engineering Wuhan University Mechanical Engineering Department Escuela Politecnica Nacional University

The present paper focuses on the erosive cavitation behavior around a plane convex hydrofoil. The Zwart-Gerber-Belamri cavitation model is implemented in a library form to be used with the OpenFOAM. The implicit large eddy simulation （ILES） is app- lied to analyze the three-dimensional unsteady cavitating flow around a plane convex hydrofoil. The numerical results in the cases under the hydrodynamic conditions, which were experimentally tested at the high speed cavitation tunnel of the l^cole Polytechnique F6d＆ale de Lausanne （EPFL）, clearly show the sheet cavitation development, the shedding and the collapse of vapor clouds. It is noted that the cavitation evolutions including the maximum vapor length, the detachment and the oscillation frequency, are captured fairly well. Furthermore, the pressure pulses due to the cavitation development as well as the complex vortex structures are reasona- bly well predicted. Consequently, it may be concluded that the present numerical method can be used to investigate the unsteady cavitation around hydrofoils with a satisfactory accuracy.

关键词： implicit large eddy simulation (ILES) unsteady partial cavitation Zwart-Gerber-Belamri cavitation model OpenFOAM,Q - criterion

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Nerve growth factor catches copper in neuronal inning

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Neural Regeneration Research 2020年第4期15卷 665-666页

作者： diego La Mendola Department of Pharmacy University of Pisa

The physiological effect of neurotrophic factors and their role in Alzheimer’s disease(AD):Neurotrophins(NTs)are a family of homologues proteins that play an essential role in neuronal cells growth,survival and *** proteins include the nerve growth factor(NGF),the brain derived neurotrophic factor(BDNF),NT-3 and NT-3,also known as NT-4/5.

关键词： Alzheimer copper differentiation.

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Two methodological approaches to assess the seismic vulnerability of masonry bridges

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Journal of Traffic and Transportation Engineering(English Edition) 2019年第1期6卷 49-64页

作者： diego Maria Barbieri Department of Civil and Environmental Engineering Norwegian University of Science and Technology Department of Civil Constructional and Environmental Engineering Sapienza University of Rome

This work describes the seismic vulnerability assessment of a railway masonry arch *** conservation state is initially investigated by means of a thorough field and laboratory test campaign, comprising destructive and non-destructive tests. Two different methods are used to evaluate the bridge seismic vulnerability. The first method adopts a deterministic approach and corresponds to a single non-linear static analysis, performed as described in the Eurocodes. The second method employs a probabilistic approach and considers the variability of the involved mechanical parameters(structure geometry and properties of the building materials) and seismic parameters(intensity of the action and site conditions). This method associates the probabilistic values of ground acceleration exceedance to the estimated seismic vulnerability. This is shown by means of fragility curves, which allow to take into consideration the uncertainty of the various components involved in the definition of the seismic vulnerability and display the seismic damage scenarios. Currently no code requires to perform this calculation procedure. In addition,this work compares the values of masonry mechanical properties specified in the Eurocodes with those obtained in an extensive investigation campaign involving more than one hundred masonry bridges. Compressive strength and longitudinal elasticity modulus are the relevant mechanical parameters investigated. The outcomes of this research can contribute to the development of a more efficient maintenance system of the masonry bridges belonging to the railway network. This has an important role when it comes to establishing the priority order of assets intervention.

关键词： Railway masonry arch bridge Bridge maintenance and conservation Masonry mechanical parameters Non-linear static analysis Seismic fragility Finite element analysis

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Alternatives to left lateral sector in paediatric liver transplantation-a systematic review on monosegmental and reduced grafts

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Hepatobiliary Surgery and Nutrition 2022年第4期11卷 567-576,I0005页

作者： Paschalis Gavriilidis Ernest hidalgo Department of Hepatopanceaticobiliary Surgery.Imperial College Healthcare NHS Trust Hammersmith HospitalLondonUK Department of Hepato-Pancreatic-Biliary Surgery and Liver Transplantation Hospital Universitari Vall d’HebronBarcelonaSpain

Background: Paediatric liver transplantation (pLT) is the treatment of choice for many liver conditions. However, it still poses relevant challenges, mainly related to the size of the recipients. Unlike in adults, excessive graft volume might represent an issue when the estimated graft-recipient-weight-ratio (GRWR) is significantly disproportionate. In this situation, the traditional left lateral sector (LLS) grafts are too big and other alternatives are required, such as monosegmental or reduced (including hyper-reduced) grafts (RLLS/HRLLS). Results with conventional LLS-pLT are excellent and replicating them with monosegmental or RLLS is challenging given (I) the technical complexity and (II) the need to overcome the large-for-size scenario. This article is to review the existing experience with monosegmental, RLLS/HRLLS grafts and appraise its results. Methods: Systematic search of the electronic databases, conducted from their inception until May 2020. Results: After scrutiny of the available literature, 16 studies were included reporting 330 patients transplanted with monosegmental and RLLS/HRLLS grafts. There were 10 re-grafts (6 of them <90 days);90% of grafts were LDLT. Overall, median recipient’s age and weight were 7 months (range, 5 days-22 months) and 5.8 kg (range, 2.6-8 kg) respectively. Median graft weight was 209 grams (range, 124-264 grams) and median GRWR was 3.5% (range, 2.7-5.6%). Hepatic artery and portal vein thrombosis overall incidence were 1.5% and 4.2%;120 out of the 330 pLT were monosegmental (37%) producing a smaller graft (median of 164 grams) and accordingly a lower GRWR (median 3.2%) compared to reduced LLS. With a median follow-up of 39 months (range, 6-87 months), the overall graft and patient survival were 84% (285/340) and 89% (295/330). Discussion: Monosegmental and RLLS/HRLLS grafts provide access to liver transplantation for very small recipients with excellent results comparable to the standard LLS.

关键词： Monosegmental monosegment(MSG) reduced hyper-reduced left lateral sector graft liver transplantation

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