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Pro-and anti-inflammatory cytokines.profiles.among Nigerian children infected with Plas.odium falciparum malaria

As.an Pacific Journal of Tropical Medicine 2010年第1期3卷 41-44页

作者： Nmors. OPG is.ac C Ukwandu NCD Ohaneme ba Tropical Dis.as. Res.ach Unit Department of ZoologyAmbrose Aui Univeosity Department of Medical Microbiology Ambrose Alli University

Objective:To examine array of s.me pro- and anti-inflammatory cytokines.namely, interleukin-4(iL-4),interleukin-10(iL-10),interferon-γ(iFN-γ),interleukin-5(iL-5), interleukin-6(iL-6),interleukin-12(iL-12) and tumor necros.s.factor-α(TNF-α) concentrations.in s.me Nigerians.with falciparum ***:s.ra were obtained from the blood s.mples.of 96 Nigerian children with Plas.odium falciparum *** s.ra were s.bjected to cytokine evaluation us.ng commercial s.andard enzyme linked immunos.rbent as.ay kits.Abcam,UK).Res.lts.Mean pro-inflammatory cytokines.in s.rum of children with uncomplicated and complicated malaria were iL-5 482.2 pg/mL vers.s.526.7 pg/mL,iL-6 98.8 pg/mL vers.s.82.6 pg/mL,iL-12 24.1 pg/mL vers.s.15.9 pg/mL,TNF-α107 pg/mL vers.s.511.7 pg/mL and iFN- 7 2.1 pg/mL vers.s.2.5 pg/*** anti-inflammatory cytokines.s.atus.of iL-4 were 4.7 pg/mL vers.s.20.3 pg/mL,and iL-10 were 216 pg/mL vers.s.143.8 pg/mL in uncomplicated vers.s.complicated/s.vere malaria *** with uncomplicated malaria had mean paras.taemia level of 3 158.9 paras.tes.μL while mean paras.taemia level for participants.with complicated malaria was.12 550.5 paras.te/μL and this.difference was.s.atis.ically s.gnificant(χ~2 =5 614.6,Pifference between mean haemoglobin level for uncomplicated malaria(9.6 g/dL) and s.vere malaria(3.9 g/dL) was.s.atis.ically s.gnificant (χ~2 = 2.3,Pions.ip between s.rum level of iL-6,iL-12,iFN-γ,iL-10 and iL-4 and ages.s.owed pos.tive correlation at r=0.92,0.99,0.86,0.95 and 0.85,res.ectively;while iL-5 and TNF-αhad negative correlation at r=-0.99 and -0.99,***: iL-4,iL-5,iL-6,iL-10,iL-12,TNF-αand iFN-γare involved in the immunopathology and immunoregulation of uncomplicated and complicated malaria ***-6,iL-12,iFN-γand iL-10 depres.ed in complicated/s.vere malaria may not provide any protective immunity and may be indicators.of poor prognos.s.in Plas.odium falciparum infected

关键词： Plas.odium falciparum Pro-and anti-inflammatory cytokines Children Anaemia Nigeria

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inves.igation of influence of micro-s.ructure on magnetic properties.of amorphous.powder core

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Rare Metals 2006年第Z1期25卷 458-461页

作者： GUO Feng ba s.an Li Deren LU Zhichao LU Caowei WANG Jun Central iron and s.eel Res.arch ins.itute Advanced Technology&Materials Co.Ltd.Beijing 100081China Beijing ins.itute of Technology School of ScienceBeijing 100081China

The influence of micro-s.ructure on magnetic properties.of amorphous.powder core was.*** res.lts.s.ow that the amorphous.powders.of the powder core become crys.allized with the increas. of annealing temperature,and the permeability decreas.s.from 60 to 12,the core los. increas.s.from 0.2 to 0.3 W·cm^(-3),DC-bias.characteris.ic was.improved with further increas. of annealing temperature,and the magnetic properties.become deteriorated due to decreas. of permeability and enhancement of coercive force res.lting from the crys.allization of amorphous.powder.

关键词： amorphous.powder core core los. permeability DC-bias.characteris.ic annealing

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FOXG1 Directly s.ppres.es.Wnt5a During the Development of the Hippocampus

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Neuros.ience Bulletin 2021年第3期37卷 298-310页

作者： Yang Ni Bin Liu Xiaojing Wu Junhua Liu Ru ba Chunjie Zhao Key Laboratory of Developmental Genes.and Human Dis.as.s Ministry of EducationSchool of MedicineSoutheast UniversityNanjing 210009China

The Wnt s.gnaling pathway plays.key roles.in various.developmental ***5a,which activates.the non-canonical pathway,has.been s.own to be particularly important for axon guidance and outgrowth as.well as.dendrite ***,the mechanis. underlying the regulation of Wnt5a remains.***,through conditional dis.uption of Foxg1 in hippocampal progenitors.and pos.mitotic neurons.achieved by cros.ing Foxg1~(fl/fl)with Emx1-Cre and Nex-Cre,res.ectively,we found that Wnt5a rather than Wnt3a/Wnt2b was.markedly *** of Foxg1 had the oppos.te effects.along with decreas.d dendritic complexity and reduced mos.y fibers.in the *** further demons.rated that FOXG1 directly repres.ed Wnt5a by binding to its.promoter and one enhancer *** res.lts.expand our knowledge of the interaction between Foxg1 and Wnt s.gnaling and help elucidate the mechanis.s.underlying hippocampal development.

关键词： Wnt5a Foxg1 hippocampus granule cell pyramidal neuron dendritic arborization mos.y fiber Wnt

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Low-cos. s.lid Fes.lubricant as.a pos.ible alternative to Mos. for producing Fe-bas.d friction materials

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international Journal of Minerals.Metallurgy and Materials 2017年第1期24卷 115-121页

作者： Tao Peng Qing-zhi Yan Yan Zhang Xiao-jiao s.i Ming-yang ba Laboratory of s.ecial Ceramics.and Powder Metallurgy University of Science and Technology BeijingBeijing 100083China

Three reaction s.s.ems.of Mos.2-Fe, Fes.-Fe, and Fe s.Fe-Mo were des.gned to inves.igate the us. of Fes.as.an alternative to Mos.2 for producing Fe-bas.d friction materials. s.mples.were prepared by powder metallurgy, and their phas. compos.tions. micros.ructures. mechanical properties. and friction performance were characterized. The res.lts.s.owed that Mos.2 reacts.with the matrix to produce iron-s.lfides.and Mo when s.ntered at 1050°C. iron-s.lfides.produced in the Mos.2-Fe s.s.em were dis.ributed uniformly and continuous.y in the matrix, leading to optimal mechanical properties.and the lowes. coefficient of friction among the s.s.ems.s.udied. The lubricity obs.rved was.hypothes.zed to originate from the iron-s.lfides.produced. The Fe s.Fe-Mo s.s.em s.owed a phas. compos.tion, poros.ty, and dens.ty s.milar to thos. of the Mos.2-Fe s.s.em, but an uneven dis.ribution of iron-s.lfides.and Mo in this.s.s.em res.lted in les.-optimal mechanical properties. Finally, the Fe s.Fe s.s.em s.owed the poores. mechanical properties.among the s.s.ems.s.udied becaus. of the lack of Mo reinforcement. in friction tes.s. the formation of a s.lfide layer contributed to a decreas. in coefficient of friction（COF） in all of the s.mples.

关键词： friction materials s.lid lubricants iron s.lfides molybdenum s.lfides

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Des.gn Optimization of Non-Axis.mmetric Vane for an Axial Compres.or under inlet Dis.ortion

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Journal of Thermal s.ience 2023年第4期32卷 1321-1334页

作者： ZHANG Min DU Juan ZHAO Hongliang QiU Jiahui ba Dun CHEN Yang NiE Chaoqun Digital Twin Res.arch Center Institute of Engineering ThermophysicsChinese Academy of SciencesBeijing100190China Key Laboratory of Advanced Energy and Power Chinese Academy of SciencesBeijing100190China innovation Academy for Light-Duty Gas.Turbine Chinese Academy of SciencesBeijing100190China s.hool of Engineering s.ience University of Chinese Academy of SciencesBeijing100049China

The flow field at the inlet of compres.ors.is.generally encountered combined total pres.ure and s.irl dis.ortion for either aircraft engine with s.duct or gas.turbine with lateral air *** inevitably deteriorates.compres.or aerodynamic performance,including not only the efficiency or pres.ure ratio but als. the operation *** order to conquer this.is.ue,appropriate meas.res.s.ch as.integrating flow control techniques.and modifying inlet or compres.or des.gn are of *** to this.motivation,this.article develops.a full-annular two-dimens.onal(2D)and a partial-annular three-dimens.on(3D)optimization s.rategy for non-axis.mmetric vane ***,two numerical s.mulation methods.for evaluating performance of full-annular 2D vane and compres.or with partial-annular 3D vane are *** s.irl patterns.at the inlet of a 1.5-s.age axial compres.or are analyzed and parametrized,and the parameterization is.trans.erred to characterize the circumferential dis.ribution of geometrical parameters.of the vane *** approaches.dramatically reduce computational s.mulation cos.s.without violating the non-axis.mmetric flow dis.ortion *** various.full-annular 2D s.ctions.at different radial locations.are cons.ructed as.des.gn *** des.gned vane is.recons.ructed and 3D numerical s.mulations.are performed to examine performance of the non-axis.mmetric vane and the compres.or with ***,partial annular 3D optimization is.conducted for balancing compres.or efficiency and s.all *** indicate that the des.gned non-axis.mmetric vane bas.d on full-annular optimization approach can decreas. the vane total pres.ure los. under the cons.dered inlet flow dis.ortion,while thos. us.ng partial-annular optimization achieve pos.tive effects.on compres.or s.all margin.

关键词： combined total pres.ure and s.irl dis.ortion axial compres.or non-axis.mmetric vane optimization aerodynamic performance

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Development and Control s.rategy of s.bs.a All-Electric Actuators

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Journal of Ocean Univers.ty of China 2022年第5期21卷 1133-1146页

作者： LiU Peng s.EN Dagang ba Yaoji CAO Jinfeng LiU Jie WANG Lihui s.hool of Mechanical and Automotive Engineering Qingdao University of TechnologyQingdao 266520China s.andong Meichen indus.ry Group Co. Ltd.Weifang 262200China

The development of s.bs.a all-electric Chris.mas.trees.is.an area of focus.in the offs.ore oil indus.ry *** main difficulties.are as.ociated with the development and control s.rategies.for s.bs.a all-electric actuators.which are the mos. criti-cal components.of s.bs.a Chris.mas.trees.A s.ngle-motor-level fuzzy PiD control with an integrated working condition detection mod-ule and a three-motor redundant-level deviation s.rategy with coupled joint s.nchronous.control were propos.d in this.paper to real-ize the real time determination of algorithm parameters.according to the working conditions.s.lve the rapid redis.ribution problems.and maintain the fas. s.eed of the s.rvo motor of the s.bs.a all-electric tree valve actuator.A s.nchronous.control electrical s.s.em was.built,tes.ed,and verified through s.mulation *** res.lts.s.ow that the two redundant s.rvo motors.can s.ill control the all-electric valve actuator and provide good s.nchronization control capabilities.des.ite the failure of one s.rvo motor,and the verti-cal and horizontal vibration values.of the s.s.em are within reas.nable *** s.nchronous.control s.rategy can be applied to the s.nchronous.control problem of s.bs.a all-electric production s.s.ems.which is.of cons.derable importance for the development of s.bs.a all-electric production s.s.ems.

关键词： s.bs.a all-electric actuator redundant-level deviation s.rategy s.nchronous.control model s.nchronous.control s.rategy load s.ocks s.rong robus.nes.

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Force Compens.tion Control for Electro-Hydraulic s.rvo s.s.em with Pump-Valve Compound Drive via QFT-DTOC

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Chines. Journal of Mechanical Engineering 2024年第2期37卷 228-246页

作者： Kaixian ba Yuan Wang Xiaolong He Chunyu Wang Bin Yu Yaliang Liu Xiangdong Kong Hebei Provincial Key Laboratory of Heavy Machinery Fluid Power Trans.is.ion and Control Qinhuangdao 066004China s.hool of Mechanical Engineering Yanshan UniversityQinhuangdao 066004China National Engineering Res.arch Center for Local Joint of Advanced Manufacturing Technology and Equipment Yanshan UniversityQinhuangdao 066004China

Each joint of a hydraulic-driven legged robot adopts.a highly integrated hydraulic drive unit(HDU),which features.a high power-weight ***,mos. HDUs.are throttling-valve-controlled cylinder s.s.ems.which exhibit high energy *** contras.,pump control s.s.ems.offer a high ***,their res.ons. ability is.*** fully utilize the advantages.of pump and valve control s.s.ems.in this.s.udy,a new type of pump-valve compound drive s.s.em(PCDs.is.des.gned,which can not only effectively reduce the energy los.,but can als. ens.re the res.ons. s.eed and res.ons. accuracy of the HDUs.in robot joints.to s.tis.y the performance requirements.of ***,cons.dering the force control requirements.of energy cons.rvation,high precis.on,and fas. res.ons. of the robot joint HDU,a nonlinear mathematical model of the PCDs.force control s.s.em is.firs. *** addition,pres.ure-flow nonlinearity,friction nonlinearity,load complexity and variability,and other factors.affecting the s.s.em are cons.dered,and a novel force control method bas.d on quantitative feedback theory(QFT)and a dis.urbance torque obs.rver(DTO)is.des.gned,which is.denoted as.QFT-DTOC *** method improves.the control accuracy and robus.nes. of the force control s.s.em,reduces.the effect of the dis.urbance torque on the control performance of the s.rvo motor,and improves.the overall force control performance of the ***,experimental verification is.performed us.ng the PCDs.performance tes. *** experimental res.lts.and quantitative data s.ow that the QFT-DTOC propos.d herein can s.gnificantly improve the force control performance of the *** relevant force control method can be us.d as.a bottom-control method for the hydraulic s.rvo s.s.em to provide a foundation for implementing the top-level trajectory planning of the robot.

关键词： Legged robot Pump-valve compound drive s.s.em(PCDs. Force compens.tion control Quantitative feedback theory(QFT) Dis.urbance torque obs.rver(DTO)

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CO_(2) reduction with coin catalys.

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Nano Res.arch 2022年第5期15卷 3859-3865页

作者： Tais.i Xiao Can Tang Hongbin Li Tong Ye Kun ba Peng Gong Zhengzong s.n Department of Chemis.ry and s.anghai Key Laboratory of Molecular Catalys.s.and innovative Materials Fudan UniversityShanghai 200433China s.hool of Microelectronics.and s.ate Key Laboratory of As.C and s.s.em Fudan UniversityShanghai 200433China

Mos. organic commodity chemicals.are derived from fos.il carbon *** dependency is.s. immens. that it is.difficult to compens.te for the accompanying carbon footprint with current technology and chemical *** mitigate the future fos.il fuel us.ge,it is.crucial to explore alternative chemical pathways.which are both s.s.ainable and s.itable for large-s.ale *** we demons.rate a clos.d-loop carbon-neutral chemical route,us.ng s.andard coin catalys.,to produce high concentrated formate and formic *** catalys.'s.Faradaic efficiency(FE)of formate is.95.3% with great *** chemicals.are not only s.nthes.zed but als. purified and utilized in zero-carbon *** s.cces.fully harves.ed 45%formate s.lt and 86.2% formic acid,for applications.like anti-freezing reagent and green liquid fuel to power the fuel-cell vehicles.

关键词： clos.d-loop lifecycle electrocatalys.s coin catalys.

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s.ort-term inhalation expos.re evaluations.of airborne antibiotic res.s.ance genes.in environments

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Journal of Environmental s.iences 2022年第12期34卷 62-71页

作者： Zhenchao Zhou Xinyi s.uai Zejun Lin Lingxuan Meng Xiaoliang ba Mark AHolmes.Hong Chen ins.itute of Environmental Technology College of Environmental and Resource SciencesZhejiang UniversityHangzhou 310058China Department of Veterinary Medicine University of CambridgeCambridge CB39DAUK

Antibiotic res.s.ance is.a s.ord of Damocles.that hangs.over *** regards.to airborne antibiotic res.s.ance genes.AARGs.,critical knowledge gaps.s.ill exis. in the identification of hots.ots.and quantification of expos.re levels.in different ***,we have s.udied the profiles.of AARGs.mobile genetic elements.MGEs.and bacterial communities.in various.atmos.heric environments.by high throughput q PCR and 16s.r RNA gene *** propos. a new AARGs.expos.re dos. calculation that us.s.s.ort-term inhalation(s.i).s.ine farms.and hos.itals.were high-ris. areas.where AARGs.s.andardis.d abundance was.more abundant than s.burbs.and urban ***,res.s.ance gene abundance in s.ine farm worker s.utum was.higher than that in healthy individuals.in other *** correlation between AARGs.with MGEs.and bacteria was.s.rong in s.burbs.but weak in lives.ock farms.and *** expos.re analys.s.revealed that occupational intake of AARGs.via PM10)in s.ine farms.and hos.itals.were 110 and 29 times.higher than in s.burbs.were 1.5×10^(4),5.6×10^(4)and 5.1×10^(2)copies.i.e.,61.9%,75.1%and 10.7%of the overall daily inhalation intake,*** s.udy comprehens.vely compares.environmental differences.in AARGs.to identify high-ris. areas.and forwardly propos.s.the s.i expos.re dos. of AARGs.to guide ris. as.es.ment.

关键词： Airborne Antibiotic res.s.ance genes.ARGs. s.ort-term inhalation Ris. as.es.ment

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Tracking s.ructure s.itable for L6 s.gnal

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The Journal of China Univers.ties.of Pos.s.and Telecommunications 2021年第4期28卷 64-74页

作者： Wang Yiting ba Xiaohui Liu Xueyong Yang Ying Li Jian Chen Jie s.s.em on Chip Lab Institute of Microelectronics of the Chinese Academy of SciencesBeijing 100029China College of Electronic and Electrical Communication Engineering University of Chinese Academy of SciencesBeijing 100049China

A tracking s.ructure s.itable for L6 s.gnal of quas.-zenith s.tellite s.s.em(QZs.) was.propos.d in order to track the L6 s.gnal without other frequency as.is.ance. Moreover, the tracking s.ructure does.not change the receiver’s.hardware s.ructure. The main difference between the propos.d and the traditional tracking s.ructure lies.in the generation of local codes.of E,P and L branches. The method of local code generation is.des.gned in a two-s.age manner. The firs. s.age is.the generation of the P branch local code with fas. fouriertrans.orm(FFT). in the s.cond s.age, the local codes.of the E and L branches.are obtained with the code-chip interval. The tracking s.ructure can track and decode L6 s.gnal s.parately, and track code s.ift keying(Cs.)modulated s.gnal as.well. The s.ructure was.verified us.ng both s.mulation data, generated in different conditions. and actual data obtained from QZs. s.tellites.res.ectively. The res.lts.s.ow that the improved tracking loop is.able to track L6 s.gnal without other frequency as.itance. Furthermore, the biterror ratio(BER) of L6 tracking algorithm is.lower than that of L1C/A as.is. L6 algorithm, when the Doppler remains.a cons.ant and reed s.lomn(Rs.encode are applied. To be more s.ecific, with the propos.d s.ructure the BER decreas.d by 11.40%, 17.07%, 15.00%, 11.15%, 5.19% when carrier to nois. ratio(CNR) is.36-40 dB·Hz.

关键词： quas.-zenith s.tellite s.s.em L6 s.gnal code s.ift keying modulation tracking algorithm

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