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Diagnostic significance of complete blood cell count and hemogramderived markers for neonatal sepsis at Southwest Public Hospitals,Ethiopia

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World Journal of Clinical Pediatrics 2024年第2期13卷 114-126页

作者： dereje abebe regassa Rahel Shumi Nagaash Bisirat Fikadu Habtu Woyesa Beyene Haile Department of Medical Laboratory Sciences Wolkite UniversityWolkite 11330Ethiopia Department of Medical Laboratory Sciences Dire Dawa UniversityDire Dawa 3000Ethiopia

BACKGROUND Neonatal sepsis is defined as an infection-related condition characterized by signs and symptoms of bacteremia within the first month of *** is the leading cause of mortality and morbidity among *** several studies have been conducted in other parts of world to assess the usefulness of complete blood count parameters and hemogram-derived markers as early screening tools for neonatal sepsis,the associations between sepsis and its complications with these blood parameters are still being investigated in our setting and are not yet part of routine *** To evaluate the diagnostic significance of complete blood cell count hemogramderived novel markers for neonatal sepsis among neonates attending public hospitals in the southwest region of Oromia,Ethiopia,through a case control *** A case control study was conducted from October 2021 to October 2023 Sociodemographic,clinical history,and laboratory test results data were collected using structured *** collected data were entered into Epi-data 3.1 version and exported to SPSS-25 for ***-square,independent sample ttest,and receiver operator characteristics curve of curve were used for analysis.A P-value of less than 0.05 was considered statistically *** In this study,significant increases were observed in the following values in the case group compared to the control group:In white blood cell(WBC)count,neutrophils,monocyte,mean platelet volume(MPV),neutrophils to lymphocyte ratio,monocyte to lymphocyte ratio(MLR),red blood cell width to platelet count ratio(RPR),red blood width coefficient variation,MPV to RPR,and platelet to lymphocyte *** MLR,a cut-off value of≥0.26 was found,with a sensitivity of 68%,a specificity of 95%,a positive predictive value(PPV)of 93.2%,and a negative predictive value(NPV)of 74.8%.The area under the curve(AUC)was 0.828(P<0.001).For WBC,a cutoff value of≥11.42 was identified,with a sensitivity of 55%,a s

关键词： Complete blood count Hemogram-derived marker Neonate Sepsis Ethiopia

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Platelet indices as predictors of poor glucoregulation in type 2 diabetes mellitus adults at Bishoftu General Hospital,Ethiopia

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World Journal of Diabetes 2024年第9期15卷 1889-1902页

作者： dereje abebe regassa Gebeyaw Arega Berihun Bisrat Fikadu Habtu Woyesa Beyene Haile Rahel Shumi Nagaash Girum Tesfaye Kiya Department of Medical Laboratory Sciences Wolkite UniversityWolkite 11330Ethiopia School of Medical Laboratory Sciences Jimma UniversityJimma 47Ethiopia Department of Medical Laboratory Sciences Dire Dawa UniversityDire Dawa 3000Ethiopia

BACKGROUND Diabetes is a chronic metabolic syndrome that has become a global public health problem with significant morbidity and *** is a pro-inflammatory and pro-thrombotic condition characterized by increased platelet activation and alterations in platelet ***,the use of platelet indices as predictors of poor glucoregulation has not been fully evaluated in this context,and evidence for their role as predictors of poor glycemic status in diabetic patients is *** To evaluate platelet indices and determine their prognostic significance in relation to inadequate glucoregulation among individuals diagnosed with type 2 diabetes at Bishoftu General Hospital in Ethiopia,from June 15 to August 12,*** A comparative cross-sectional study was conducted in 261 participants including 174 individuals with type 2 diabetes mellitus(T2DM)and 87 non-diabetic *** systematic random sampling technique was used to select *** were collected using structured questionnaires,physical measurements,checklists,and laboratory *** parameters and fasting blood glucose levels were determined from blood samples using Sysmex-XN550 and CobasC311 analyzers,*** hematology analyzer output was checked and participants were also screened for malaria parasites using a prepared blood *** data were entered into Epi-data version 3.1 and exported to SPSS version 25 for ***χ2 test,Mann-Whitney U test,Kruskal-Wallis test,post hoc test,Spearman correlation,and receiver operating characteristic curve were used for analysis.A P value<0.05 was considered statistically *** The results of our study indicate that diabetic patients have significantly higher levels of platelet distribution width(PDW),mean platelet volume(MPV),platelet large cell ratio(PLCR),and plateletcrit(PCT)compared to healthy individuals(P<0.001).Furthermore,these indices were found to be significantly elevated in individuals wi

关键词： Platelet indices Type 2 diabetes mellitus Controls Adult Ethiopia

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Effect of Intercropping of Legumes and Rates of Nitrogen Fertilizer on Yield and Yield Components of Maize (<i>Zea mays</i>L.) at Arba Minch

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American Journal of Plant Sciences 2017年第9期8卷 2159-2179页

作者： Ewnetie Takele Zenebe Mekonnen dereje Tsegaye Arega abebe Department of Plant Science Arba Minch University Arba Minch Ethiopia Arba Minch Agricultural Research Center Arba Minch Ethiopia

Intercropping of legumes and cereals, an old practice since ancient civilization, plays pivotal role to increase land use efficiency, improve income and food production per unit area and minimize the risks of crop failure for small scale farmers. Thus, field experiment was conducted to determine the effect of intercropping of legumes and rates of nitrogen fertilizer on yield and yield components of maize (Zea mays L.). The experiment consisted of 0, 23, 46, 69 and 92 kg·N·ha-1 and sole maize, maize + commom bean, maize + common bean - mung bean cropping systems with Random Complete Block Design factorial experiment in three replications using maize variety, “BH-140”, common bean variety (Hawassadume) and mung bean variety. Maximum plant heights, dry matter and grain yield, were observed from sole cropped maize and maize + common bean, when applying 92 kg·N·ha-1. Significantly higher total Land Equivalent Ratio of 2.2, Gross Monetary Value of 87,191 birr ha-1, Monetary Advantage of 47,068.2 Birr ha-1, total productivity (80,568.49 birr) and net return (55,214.0 birr) were recorded from maize + common bean - mung bean. The, maximum marginal rate of return was obtained from maize + common bean - mung bean and applying 69 kg·N·ha-1 (1080%). Thus, farmers should be advised to practice cropping of maize + common bean - mung with 69 kg·N·ha-1 to get economical maize production.

关键词： Phenology Cropping System Gross Monetary Value Land Equivalent Ratio

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