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Inhaled nitric oxide and treatment of hypoxic respiratory failure

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Acta Pharmacologica Sinica 1997年第6期18卷 66-67页

作者： Richard A EHRENKRANZ (department of Pediatrics, Yale university school of Medicine, new Haven CT, usa) departmentofPediatrics YaleUniversitySchoolofMedicineNewHavenCTUSA.

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ＩｎｈａｌｅｄｎｉｔｒｉｃｏｘｉｄｅａｎｄｔｒｅａｔｍｅｎｔｏｆｈｙｐｏｘｉｃｒｅｓｐｉｒａｔｏｒｙｆａｉｌｕｒｅＲｉｃｈａｒｄＡＥＨＲＥＮＫＲＡＮＺ（ＤｅｐａｒｔｍｅｎｔｏｆＰｅｄｉａｔｒｉｃｓ，ＹａｌｅＵｎｉｖｅｒｓｉｔｙＳｃｈｏｏｌｏｆＭｅｄｉ...

关键词： nitric oxide respiratory therapy neonatology clinical trials

INTERIOR ERROR ESTIMATES FOR NONCONFORMINGFINITE ELEMENT METHODS OF THE STOKES EQUATIONS

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Journal of Computational mathematics 1999年第5期17卷 475-494页

作者： Xiao-bo Liu(department of mathematics and Computer Science Clarkson university Box 5815, Potsdam,ny 13699-5815, usa) Clarkson Univ Dept Math & Comp Sci Potsdam NY 13699 USA

Interior error estimates are derived for nonconforming stable mixed finite element discretizations of the stationary Stokes equations. As an application, interiorconvergences of difference quotients of the finite element solution are obtained forthe derivatives of the exact solution when the mesh satisfies some translation invariant condition. For the linear element, it is proved that the average of thegradients of the finite element solution at the midpoint of two interior adjacenttriangles approximates the gradient of the exact solution quadratically.

关键词： Interior error estimates Nonconforming element Stokes equations.

Tannin inhibits HIV-1 entry by targeting gp41

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Acta Pharmacologica Sinica 2004年第2期 87-92页

作者： Lin Lü2, Shu-wen LIU2,3, Shi-bo JIANG3, Shu-guang WU2,4 2Institute of Pharmaceutical Sciences of the First Medical university of PLA, Key Lab of GD for Screening of new Drug, Guangzhou, Guangdong 510515, China Lindsley F Kimball Research Institute, new york Blood Center, new york, ny 10021, usa

AIM: To investigate the mechanism by which tannin inhibits HIV-1 entry into target cells. METHODS: The inhibitory activity of tannin on HIV-1 replication and entry was detected by p24 production and HIV-1-mediated cell fusion, respectively. The inhibitory activity on the gp41 six-helix bundle formation was determined by an improved sandwich ELISA. RESULTS: Tannins from different sources showed potent inhibitory activity on HIV-1 replication, HIV-1-mediated cell fusion, and the gp41 six-helix bundle formation. CONCLUSION: Tannin inhibits HIV-1 entry into target cells by interfering with the gp41 six-helix bundle formation, thus blocking HIV-1 fusion with the target cell.

关键词： tannin drug dose-response relationship enzyme-linked immunosorbent assay HIV envelope pro- tein gp41 phenols plant extracts medical plants

Quantum dynamics study for reaction of H_2 + OD→H + HOD

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Chinese Science Bulletin 1997年第2期42卷 116-120页

作者： ZHANG Yici, ZHANG Yanbing, ZHANG DeshengZHANG Qinggang, Dong H. Zhang and John Z. H. Zhang1. department of Physics, Shandong Teachers university, Jinan 250014, China 2. department of Chemistry, new york Uni versity, new york 10003, usa department of Physics Shandong Teachers University Jinan 250014 China

TIME-dependent （TD） quantum wave packet theory, with a relatively small amount of computational effort, has been widely used in quantum dynamics calculation of atom and molecule reaction scattering. Many computational scaling advantages of the TD method can be found apparently in polyatomic system. In this note, by using the TD quantum wave packet method with the potential-averaged 5D model （PA5D）, we give the calculated results of reaction probabilities, cross sections and rate constants for the H2 + OD reaction. The energyprojection method is used to transform the TD wave function into the TI (energy-indepen-

关键词： propagation probability cross section rate constant.

Quasisymmetric property for conjugacies between Anosov diffeomorphisms of the two-torus

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Science China mathematics 2010年第3期53卷 663-670页

作者： HU HuYi 1 & JIANG YunPing 2, 1 department of mathematics, Michigan State university, East Lansing, MI 48824, usa 2 department of mathematics, the graduate Center and Queens College of CUny, Flushing, ny 11367, usa 1. department of mathematics Michigan State University East Lansing MI 48824 USA2. Department of Mathematics the Graduate Center and Queens College of CUNY Flushing NY 11367 USA

We prove that the restrictions of the conjugacy between two Anosov diffeomorphisms of the twotorus to the stable and unstable manifolds are quasisymmetric homeomorphisms.

关键词： quasisymmetry Anosov diffeomorphisms conjugacy Hlder condition Markov partition

Static Theory for Planar Ferromagnets and Antiferromagnets

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Acta Mathematica Sinica,English Series 2001年第4期17卷 541-580页

作者： Feng Bo HANG Fang Hua LIN Courant Institute, 251 Mercer Street. new york. ny 10012, usa Dept. of Math, Princeton university, Fine Hall. Washington Road, Princeton, NJ 08544 usa. Courant Institute New York USA

Here we generalize the "BBH"-asymptotic analysis to a simplified mathematical model for tho planar ferromaguets and antiferromagnets. To develop such a static theory is a necessary step for a rigorous mathematical jus... 详细信息

关键词： Ginzburg-Landau-type equations Vortices Minimizing harmonic maps Gradient cstimate Radial solutions Stability Quantization

Cardiac sympathetic nerve terminal function in congestive heart failure

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Acta Pharmacologica Sinica 2007年第7期28卷 921-927页

作者： Chang-seng LIANG school of Medicine and Dentistry,university of Rochester,Rochester,new york 14642,usa school of Medicine and Dentistry University of Rochester Rochester NewYork 14642 USA. chang-seng_liang@urmc.rochester.edu.

Increased cardiac release of norepinephrine (NE) and depleted cardiac stores ofNE are two salient features of the human failing *** from my labo-ratory have shown that these changes are accompanied by a functional defect ofNE uptake in the cardiac sympathetic nerve *** studies have shownthat the decrease of NE uptake is caused by reduction of NE transporter density inthe sympathetic nerve endings,and this change is responsible,at least in part,forthe increased myocardial interstitial NE,decreased myocardial adrenoceptordensity,and increased myocyte apoptosis in experimental *** also provided evidence in both intact animals and cultured PC12 cells thatthe decrease of NE transporter is induced by the actions of oxidative metabolitesof exogenous NE,involving endoplasmic reticulum stress and impairedN-glycosylation of the NE *** change in the cardiac sympathetic NEuptake function,as demonstrated by [123I] metaiodobenzylguanidine in humanstudies,may not only serve as an important prognostic variable in patients withcongestive heart failure,but also be used as a surrogate for the efficacies ofvarious therapeutic interventions for heart ***,increasing evidencesuggests and further studies are needed to show that the cardiac sympatheticnerve terminal function may be a direct target for pharmacologic treatment ofcongestive heart failure.

关键词： neurotransmitter transporter norepinephrine congestive heart failure nerve growth factors antioxidants

Boundary Layer Theory and the Zero-Viscosity Limit of the Navier-Stokes Equation

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Acta Mathematica Sinica,English Series 2000年第2期16卷 207-218页

作者： Weinan E department of mathematics and Program in Applied and Computational mathematics,Princeton university,usa department of mathematics and Program in Applied and Computational mathematics Princeton University Princeton USA

A central problem in the mathematical analysis of fluid dynamics is the asymptotic limit of the fluid flow as viscosity goes to *** is particularly important when boundaries are present since vorticitv is typically generated at the boundary as a result of boundary layer *** boundary laver theory,developed by Prandtl about a hundred years ago,has become a standard tool in addressing these *** at the mathematical level,there is still a lack of fundamental understanding of these questions and the validity of the boundary layer *** this article,we review recent progresses on the analysis of Prandtl’s equation and the related issue of the zero-viscosity limit for the solutions of the Navier-Stokes *** also discuss some directions where progress is expected in the near future.

关键词： Boundary layer Blow-up Zero-viscosity limit Prandtl’s equation