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Pigeon Robot for Navigation Guided by Remote Control:System Construction and Functional Verification

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Journal of Bionic Engineering 2021年第1期18卷 184-196页

作者： Zhengyue Zhou denghui liu Hong Sun Wenbo Xu Xinmao Tian Xiaoyuan Li Han Cheng Zhenlong Wang School of Life Sciences Zhengzhou UniversityZhengzhou 450001China School of Electrical Engineering Zhengzhou UniversityZhengzhou 450001China School of Physical Education(Main Campus) Zhengzhou UniversityZhengzhou 450001China

Animal robots have outstanding advantages over traditional robots in their own energy supplies,orientation,and natural concealment,delivering significant value in the theories and applications of neural science,national security,and other ***,many animal robots have been fabricated,but researches about the applications of avian robots are still *** this study,we constructed a Pigeon Robot System(PRS),optimized the electric stimulation parameters,assessed the electric stimulus of navigation,and evaluated the navigation efficiency in the *** pulse constant current pattern was adapted,and the optimal stimulus parameters of 4 nuclei tested were of amplitude 0.3 mA,5 pulse trains,frequency 25 Hz,5 pulses,and a 25%duty *** ratio of left and right steering behavior response to electric stimulus dorsointermedius ventralis anterior nuclei was 67%and 83%,respectively(mean value 75%).Electrical stimulation efficiency was 0.34-0.68 and path efficiency was 0.72-0.85 among pigeon robot individuals in the open *** electrical stimulation efficiency nor path efficiency differed significantly(P>0.05),suggesting that the navigational PRS performance was not biased in either *** can achieve continuous navigation along simple pathways and provide the necessary application infrastructure and technical reference for the development of animal robot navigation technology.

关键词： pigeon robot bionic robot system construction navigation functional verification

Different coding characteristics between flight and freezing in dorsal periaqueductal gray of mice during exposure to innate threats

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Animal Models and Experimental Medicine 2022年第6期5卷 491-501页

作者： denghui liu Shouhao Li Liqing Ren Xinyu liu Xiaoyuan Li Zhenlong Wang School of Electrical and Information Engineering Zhengzhou UniversityZhengzhouChina School of Intelligent Manufacturing Huanghuai UniversityZhumadianChina School of Life Sciences Zhengzhou UniversityZhengzhouChina

Background:Flight and freezing are two vital defensive behaviors that mice display to avoid natural *** they are exposed to innate threats,visual cues are processed and transmitted by the visual system into the emotional nuclei and finally transmitted to the periaqueductal gray(PAG)to induce defensive ***,how the dorsal PAG(dPAG)encodes the two defensive behaviors is ***:Multi-array electrodes were implanted in the dPAG nuclei of C57BL/6 *** kinds of visual stimuli(looming and sweeping)were used to induce defensive behaviors in *** signals under different defense behaviors were recorded,and the encoding characteristics of the two behaviors were extracted and analyzed from spike firing and frequency ***,synchronization of neural activity during the defense process was ***:The neural activity between flight and freezing behaviors showed different firing patterns,and the differences in the inter-spike interval distribution were mainly reflected in the 2–10 ms *** frequency band activities under both defensive behaviors were concentrated in the theta band;the active frequency of flight was~8to 10 Hz,whereas that of freezing behavior was~6 to 8 *** network connection density under both defense behaviors was significantly higher than the period before and after defensive behavior occurred,indicating that there was a high synchronization of neural activity during the defense ***:The dPAG nuclei of mice have different coding features between flight and freezing behaviors;during strong looming stimulation,fast neuro-i nstinctive decision making is required while encountering weak sweeping stimulation,and computable planning late behavior is predicted in the early *** frequency band activities under both defensive behaviors were concentrated in the theta *** was a high synchronization of neural activity during the defense process,which may be a key factor trigg

关键词： C57BL/6 mice dorsal periaqueductal gray flight and freezing innate threats neural coding

Suppressing the Undesirable Energy Loss in Solution-Processed Hyperfluorescent OLEDs Employing BODIPY-Based Hybridized Local and Charge-Transfer Emitter

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Energy & Environmental Materials 2024年第2期7卷 372-380页

作者： Xuewei Nie Zafar Mahmood denghui liu Mengke Li Dehua Hu Wencheng Chen Longjiang Xing Shijian Su Yanping Huo Shaomin Ji School of Chemical Engineering and Light Industry Guangdong University of TechnologyGuangzhou 510006China State Key Laboratory of Luminescent Materials and Devices and Institute of Polymer Optoelectronic Materials and Devices South China University of TechnologyGuangzhou 510640China

Hyperfluorescent organic light-emitting diodes(HF-OLEDs)approach has made it possible to achieve excellent device performance and color purity with low roll-off using noble-metal-free pure organic *** significant progress,the performance of HF-OLEDs is still unsatisfactory due to the existence of a competitive dexter energy transfer(DET)*** this contribution,two boron dipyrromethene(BODIPY)-based donor-acceptor emitters(BDP-C-Cz and BDP-N-Cz)with hybridized local and charge transfer characteristics(HLCT)are introduced in the HF-OLED to suppress the exciton loss by dexter mechanism,and a breakthrough performance with low-efficiency roll-off(0.3%)even at high brightness(1000 cd m^(-2))is *** is demonstrated that the energy loss via the DET channel can be suppressed in HF-OLEDs utilizing the HLCT emitter,as the excitons from the dark triplet state of such emitters are funneled to its emissive singlet state following the hot-exciton *** developed HF-OLED device has realized a good maximum external quantum efficiency(EQE)of 19.25%at brightness of 1000 cd m^(-2)and maximum luminance over 60000 cd m^(-2),with an emission peak at 602 nm and Commission International de L'Eclairage(CIE)coordinates(0.57,0.41),which is among the best-achieved results in solution-processed *** work presents a viable methodology to suppress energy loss and achieve high performance in the HF-OLEDs.

关键词： BODIPY hyperfluorescence organic light-emitting diodes solution-process

Characterization of functional transposable element enhancers in acute myeloid leukemia

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Science China(Life Sciences) 2020年第5期63卷 675-687页

作者： Yingying Zeng Yaqiang Cao Rivka Sukenik Halevy Picard Nguyen denghui liu Xiaoli Zhang Nadav Ahituv Jing-Dong JHan CAS Key Laboratory of Computational Biology CAS-MPG Partner Institute for Computational BiologyShanghai Institute of Nutrition and HealthChinese Academy of Sciences Center for Excellence in Molecular Cell ScienceCollaborative Innovation Center for Genetics and Developmental BiologyShanghai Institutes for Biological SciencesChinese Academy of SciencesShanghai 200031China Department of Bioengineering and Therapeutic Sciences University of California San FranciscoSan Francisco 94158USA Institute for Human Genetics University of California San FranciscoSan Francisco 94143USA Sackler School of Medicine Tel-Aviv UniversityTel Aviv 6997801Israel Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative BiologyPeking UniversityBeijing 100871China

Transposable elements(TEs)have been shown to have important gene regulatory functions and their alteration could lead to disease *** myeloid leukemia(AML)develops as a consequence of a series of genetic changes in hematopoietic precursor cells,including mutations in epigenetic ***,we set out to study the gene regulatory role of TEs in *** first explored the epigenetic landscape of TEs in AML patients using ATAC-seq *** show that a large number of TEs in general,and more specifically mammalian-wide interspersed repeats(MIRs),are more enriched in AML cells than in normal blood *** obtained a similar finding when analyzing histone modification data in AML *** Ontology enrichment analysis showed that genes near MIRs in open chromatin regions are involved in *** functionally validate their regulatory role,we selected 19 MIR regions in AML cells,and tested them for enhancer activity in an AML cell line(Kasumi-1)and a chronic myeloid leukemia(CML)cell line(K562);the results revealed several MIRs to be functional *** together,our results suggest that TEs are potentially involved in myeloid leukemogenesis and highlight these sequences as potential candidates harboring AML-associated variation.

关键词： transposable element enhancer promoter MIR acute myeloid leukemia

校本课程设计方案质量研究——基于全国2200份校本课程设计方案的实证分析

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教育发展研究 2016年第10期36卷 78-84页

作者：刘登珲华东师范大学课程与教学研究所博士研究生上海200062

深化课程改革背景下有必要探明我国校本课程设计方案质量建设状况,进而为新时期校本课程持续发展廓清迷思、指明方向。在构建校本课程设计方案评估工具基础上对来自全国的2200份校本课程设计方案质量进行分析。研究发现:校本课程设计方... 详细信息

深化课程改革背景下有必要探明我国校本课程设计方案质量建设状况,进而为新时期校本课程持续发展廓清迷思、指明方向。在构建校本课程设计方案评估工具基础上对来自全国的2200份校本课程设计方案质量进行分析。研究发现:校本课程设计方案整体质量堪忧,距离专业化水平有较大差距;"技术性"是校本课程设计方案最薄弱的环节;校本课程设计质量在学段、课程类型、地区上存在差异;合作开发、健全的校本支持系统对校本课程设计方案质量有促进作用。未来校本课程开发应从数量普及、结构均衡向质量提升转移;深化校本课程开发公平建设,弥合区域、学段差异;健全校本课程开发支持系统,为教师参与校本课程开发创设良好环境。

关键词：校本课程设计方案质量实证研究

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詹姆斯·比恩课程统整思想研究

全球教育展望 2017年第4期46卷 30-39页

作者：刘登珲华东师范大学课程与教学研究所

詹姆斯·比恩(James ***)关于课程统整的思想是其民主信念的"隐微"表达。他用现代民主理念改造"课程统整",把研究视线从"如何统整"转移到"为何统整""谁来统整""统整什么"上来,开辟了一条通往民主的课程之路。朴素的民主观制约了比恩的... 详细信息

詹姆斯·比恩(James ***)关于课程统整的思想是其民主信念的"隐微"表达。他用现代民主理念改造"课程统整",把研究视线从"如何统整"转移到"为何统整""谁来统整""统整什么"上来,开辟了一条通往民主的课程之路。朴素的民主观制约了比恩的课程想象,一些未竟的问题,如民主理念的教育适切性、课程统整主题窄化、课程统整设计中的组织形式等仍有待完善。系统分析比恩的课程统整思想,对超越工具取向的课程统整模式、开创具有本土特色的课程统整模式具有借鉴价值。

关键词：民主课程统整詹姆斯·比恩

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我国校外教育功能定位流变及其现代转向

湖南师范大学教育科学学报 2016年第5期15卷 114-119页

作者：刘登珲华东师范大学课程与教学研究所上海200062

功能定位是我国校外教育从外延发展走向内涵发展面临的首要问题。自新中国成立以来我国校外教育经历了萌芽期、初创期、破坏与恢复期、发展期、转型期五个阶段,不同阶段其功能定位受历史逻辑的驱策而嬗变发展。校外教育功能定位由"延伸"... 详细信息

功能定位是我国校外教育从外延发展走向内涵发展面临的首要问题。自新中国成立以来我国校外教育经历了萌芽期、初创期、破坏与恢复期、发展期、转型期五个阶段,不同阶段其功能定位受历史逻辑的驱策而嬗变发展。校外教育功能定位由"延伸"、"补充"、"并举"到"协同"转向具有内在必然性。立足自身,强化校外教育服务的专业化建设;破除壁垒,构建一体化的政策执行、监督机制;区域疏导,搭建校内外联动的组织平台是校外教育融身大教育体系,与学校教育"一体两翼"推进素质教育发展继而实现校外教育功能定位"协同"转向的基本路径。

关键词：校外教育功能定位历史考察

转型的阵痛:新时期我国校外教育课程建设问题透视——对华东地区十二所校外教育机构的访谈分析

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全球教育展望 2016年第1期45卷 73-83页

作者：刘登珲华东师范大学课程与教学研究所

新世纪以来,我国校外教育呈现由场馆建设(硬件)到内涵发展(软件)转变的态势,校外教育科学化、规范化建设及其如何与学校教育"一体两翼"、协同推动素质教育发展,成为当前校外教育理论、实践工作者的重要使命。内涵发展意味着深掘、内挖... 详细信息

新世纪以来,我国校外教育呈现由场馆建设(硬件)到内涵发展(软件)转变的态势,校外教育科学化、规范化建设及其如何与学校教育"一体两翼"、协同推动素质教育发展,成为当前校外教育理论、实践工作者的重要使命。内涵发展意味着深掘、内挖校外教育场所的育人潜力,从"蹦蹦跳跳"经验化、随意性的活动范畴向科学、高效且与学校课程有机沟通、衔接的规范化的课程体系迈进。本文通过对华东地区十二所不同类别的公益性校外教育机构负责人、教务管理人员及一线教师的访谈分析,揭示了当前我国校外教育课程建设领域亟待解决的问题,并提出通过机构层面的课程建设低重心、针对性、自下而上的解决课程问题进而恢复校外教育机构的课程"造血"功能的重要性。

关键词：校外教育课程问题

竞斗与融合:当代美国课程统整范式演进的内在逻辑

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外国教育研究 2022年第6期49卷 3-19页

作者：刘登珲江南大学教育学院江苏无锡214122

在课程社会史的关照下,有必要从“共时”与“历时”、“静态”与“动态”、“实然”与“或然”多个角度刻画当代美国课程统整范式的存在方式和运行特质,澄清主导课程统整范式背后的行为主体与社会结构,以及二者的互动关系。为取得学校... 详细信息

在课程社会史的关照下,有必要从“共时”与“历时”、“静态”与“动态”、“实然”与“或然”多个角度刻画当代美国课程统整范式的存在方式和运行特质,澄清主导课程统整范式背后的行为主体与社会结构,以及二者的互动关系。为取得学校的“课程领导权”,代表美国垄断资本的“行动派”与代表中产阶层和底层大众利益的“学院派”,在“课程统整”的“竞斗场”上彼此竞斗又相互融合,形成“三足鼎立”的格局。“行动者”借助“课程统整”的概念工具再生了各自团体的利益诉求,精英的自我复制、中产的自我实现、底层的自我超越诉求赋予了课程统整范式多重内涵并为课程统整范式演化注入了动力。从“还原论”走向“超越还原论”、从“知识优化”走向“整全发展”、从“客体优位”走向“实践优位”、从“技术控制”走向“实践生成”是主导美国课程统整范式演进的学脉线索,也是美国课程统整的“未来画像”。

关键词：美国课程统整范式课程领导权