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Pt and Te codoped ultrathin MoS_(2) nanosheets for enhanced hydrogen evolution reaction with wide pH range

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Rare Metals 2022年第2期41卷 378-384页

作者： Cui-Hua An Wei Kang Qi-bo deng Ning Hu National Engineering Research Center for Technological Innovation Method and Tool School of Mechanical EngineeringHebei University of TechnologyTianjin 300401China Key Laboratory of Advanced Energy Materials Chemistry(MOE) College of ChemistryNankai UniversityTianjin 300071China Institute for New Energy Materials&Low-Carbon Technologies School of Materials Science and EngineeringTianjin University of TechnologyTianjin 300384China State Key Laboratory of Reliability and Intelligence Electrical Equipment Hebei University of TechnologyTianjin 300130China

Transition metal dichalcogenides,especially MoS_(2),have been examined as promising catalysts for hydrogen evolution reaction(HER).Meanwhile,MoS_(2)with various nanostructures and exposed more active sites has been broadly explored for boosting the HER performances at wide pH ***,a synergistic Pt and Te codoping strategy has been used to enhance the catalytic performance(including reducing the overpotential and promoting the HER reaction kinetics)of ultrathin MoS_(2)nanosheets in alkaline and acid electrolytes,which has delivered better than single Pt doping or single Te doping.

关键词： doping kinetics synergistic

基于自动化提取HCV RNA荧光定量检测系统的性能验证

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广东医科大学学报 2024年第1期42卷 73-77页

作者：邓波何彪廖亚龙黄革高州市人民医院检验科广东高州525200 南方医科大学附属广东省人民医院(广东省医学科学院)检验科广东广州510000

目的基于Stream SP96全自动核酸提取仪、ABI7500实时荧光定量PCR仪对丙型肝炎病毒(HCV)RNA定量检测系统的性能指标进行验证。方法依据《临床实验室对商品定量试剂盒分析性能的验证》WS/T 420-2013性能验证方案,采用Stream SP96全自动... 详细信息

目的基于Stream SP96全自动核酸提取仪、ABI7500实时荧光定量PCR仪对丙型肝炎病毒(HCV)RNA定量检测系统的性能指标进行验证。方法依据《临床实验室对商品定量试剂盒分析性能的验证》WS/T 420-2013性能验证方案,采用Stream SP96全自动核酸提取平台及ABI7500荧光定量PCR仪检测HCV RNA,对其准确度、精密度、线性区间、检测限、定量限和抗干扰能力等进行方法学性能验证。结果低、高浓度标准物质的均值与靶值的误差分别为0.20和0.25,均小于靶值对数值±0.4 log;低浓度样本的批内、批间不精密度变异系数值分别为0.79%、1.01%,高浓度样本的批内、批间不精密度变异系数值分别为0.52%、1.22%,均0.980,线性区间可达20~1.0×10^(8),呈良好线性(R^(2)=0.997 3);检出限为20 IU/mL,最低定量限为50 IU/mL;含胆红素(300 mg/L)、血红蛋白(300 g/L)、甘油三酯(3 000 mg/L)的干扰物质对样本检测结果无影响。结论 HCV RNA实时荧光PCR定量法检测系统准确度、精密度、线性范围、检出限、定量限、抗干扰能力均符合厂家声明,能够满足临床对HCV RNA定量检测的需求。

关键词： HCV RNA 荧光法性能验证

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深圳朗峻广场项目复杂高层结构设计

建筑结构 2024年第11期54卷 46-52页

作者：林超伟王兴法周云吴震高义奇邓波柏涛国际工程设计顾问(深圳)有限公司深圳518031 广州大学土木工程学院广州510006 深圳市清华苑建筑与规划设计研究有限公司深圳518054

朗峻广场项目是多个整体建筑体块错落叠合而成的复杂建筑,其造型独特,具有45m跨度刚性连接连体、斜撑转换、竖向构件收进和大悬挑等特征,结构采用框架-多筒体剪力墙体系。阐述了刚性连体构成、转换结构的设计选型与思路,重点介绍了筒体... 详细信息

朗峻广场项目是多个整体建筑体块错落叠合而成的复杂建筑,其造型独特,具有45m跨度刚性连接连体、斜撑转换、竖向构件收进和大悬挑等特征,结构采用框架-多筒体剪力墙体系。阐述了刚性连体构成、转换结构的设计选型与思路,重点介绍了筒体剪力墙墙肢的关键设计要点。此外,根据项目特点确定结构的性能目标,提出了小震设计参数结果的合理提取方法和中震的设计原则,复核结构在大震下的抗震性能并根据结果采取适宜的抗震措施。结果表明本工程结构具有较好的抗震性能,采用的设计方法可行。

关键词：复杂高层结构框架-多筒体剪力墙体系筒体收进复杂连接转换结构抗震性能

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Efficacy of Wen-Luo-Tong on Peripheral Neuropathy Induced by Chemotherapy or Target Therapy: A Randomized, Double-Blinded, Placebo-Controlled Trial

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Chinese Journal of Integrative Medicine 2022年第7期28卷 579-585页

作者： deng bo JIA Li-qun WAN Dong-gui WANG Bao-yi CHENG Zhi-qiang deng Chao Center of Science and Technology China-Japan Friendship HospitalBeijing 100029China Integrative Oncology Department of Chinese Medicine and Western Medicine China-Japan Friendship HospitalBeijing 100029China

Objective: To evaluate the efficacy of Wen-Luo-Tong Granules(WLT) local administration in the treatment of patients with peripheral neuropathy(PN) induced by chemotherapy or target therapy. Methods: This study is a randomized, double-blinded, and placebo-controlled trial. Seventy-eight patients with PN induced by chemotherapy or target therapy were enrolled from China-Japan Friendship Hospital between July 2019 and January 2020. They were randomly assigned to WLT(39 cases) and control groups(39 cases) using a block randomization method. The WLT group received WLT(hand and foot bath) plus oral Mecobalamin for 1 week, while the control group received placebo plus oral Mecobalamin. The primary endpoint was PN grade evaluated by the National Cancer Institute-Common Toxicity Criteria for Adverse Events(NCI-CTCAE). The secondary endpoints included quantitative touch-detection threshold, neuropathy symptoms, Quality of Life QuestionnaireChemotherapy Induced Peripheral Neuropathy(QLQ-CIPN20), and Quality of Life Questionnaire-Core30(QLQ-C30). Results: After treatment, the PN grade in the WLT group was significantly lower than that in the control group(1.00±0.29 vs. 1.75±0.68, P<0.01). The total effective rate in the WLT group was significantly higher than that in the control group(82.05% vs. 51.28%, P<0.01). Compared with the control group, the touchdetection thresholds at fingertips, neuropathy symptom score, QLQ-CIPN 20(sensory scale, motor scale, autonomic scale, and sum score), and QLQ-C30(physical functioning, role functioning, emotional functioning, and global health) in the WLT group significantly improved after treatment(P<0.01 or P<0.05). Conclusion: WLT local administration was significantly effective in the treatment of patients with PN induced by chemotherapy or target therapy.(Trial registration No. ChiCTR1900023862)

关键词： peripheral neuropathy chemotherapy target therapy Chinese medicine Wen-Luo-Tong randomized controlled trial

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磁性液体性能及运行工况对密封耐压值的影响

润滑与密封 2024年第5期49卷 129-135页

作者：陈芳张杰李正贵李望旭邓波闫盛楠颜招强西华大学能源与动力工程学院四川成都610039 西华大学流体及动力机械教育部重点实验室四川成都610039 自贡兆强密封制品实业有限公司四川自贡643020

为研究不同种类磁性液体及密封工况对密封效果的影响,以Fe_(3)O_(4)为磁性颗粒,以链状氟醚油为基液,制备一系列不同颗粒含量、基液分子量的磁性液体,对磁性颗粒及磁性液体的结构、性能进行表征,在搭建的密封试验台上测试磁性液体种类及... 详细信息

为研究不同种类磁性液体及密封工况对密封效果的影响,以Fe_(3)O_(4)为磁性颗粒,以链状氟醚油为基液,制备一系列不同颗粒含量、基液分子量的磁性液体,对磁性颗粒及磁性液体的结构、性能进行表征,在搭建的密封试验台上测试磁性液体种类及运行工况对密封耐压效果的影响。结果表明:制备的磁性颗粒粒径为纳米级,呈近球形形貌,具有较高的饱和磁化强度,磁性液体具有较好的分散稳定性;随颗粒含量增加、基液分子量增大,密封耐压值先增大后减小;在颗粒质量分数为30%、基液分子量为4600 g/mol时,密封耐压值最高;随主轴转速增大,密封耐压值逐渐减小;随密封时间延长,密封耐压值先减小后趋于稳定。

关键词：磁性液体密封耐压值饱和磁化强度密封寿命分散稳定性

New insights into immune cell diversity in acute kidney injury

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Cellular & Molecular Immunology 2023年第6期20卷 680-682页

作者： bo deng Sutian Wang Peihui Zhou Feng Ding Division of Nephrology Shanghai Ninth People's HospitalShanghai Jiao Tong University School of MedicineShanghaiChina State Key Laboratory of Livestock and Poultry Breeding Guangdong Key Laboratory of Animal Breeding and NutritionInstitute of Animal ScienceGuangdong Academy of Agricultural SciencesGuangzhouChina

Acute kidney injury(AKI)is a frequent complication affecting hospitalized patients in medical wards and usually arises from ischemia‒reperfusion injury(IRI),sepsis,and nephrotoxic *** infiltration and activation of immune cells in the kidney induce a continuous inflammatory response,which is characterized by substantial cytotoxicity that ultimately exacerbates kidney damage[1].The role of individual immune cell types in AKI has been mostly investigated in previous ***,despite the successful results in experimental studies,treatments targeting a broad immune response have yielded minor improvements in patient outcomes,in part due to the imprecise understanding of immune cell ***,the focus of AKI research has shifted toward gaining insight into the heterogeneity and dynamic changes in immune cells with novel experimental approaches such as single-cell analysis,thereby redefining AKI pathophysiology.

关键词： kidney drugs Acute

高锁螺母用7075T73铝合金韧性断裂准则研究

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轻合金加工技术 2024年第1期52卷 45-52,63页

作者：傅垒牛关梅邓博娄燕山刘成中铝材料应用研究院有限公司北京昌平102209 中国航空工业标准件制造有限责任公司贵州贵阳550014 西安交通大学机械工程学院陕西西安710049

通过单向拉伸试验,获取高锁螺母用7075T73铝合金的力学性能和应力应变曲线,拟合求解其Swift/Hockett-Sherby硬化模型参数。设计了2种缺口拉伸试样、3种缺口压缩试样,并结合相应的有限元模型分析,获取不同应力状态下材料的断裂应变、平... 详细信息

通过单向拉伸试验,获取高锁螺母用7075T73铝合金的力学性能和应力应变曲线,拟合求解其Swift/Hockett-Sherby硬化模型参数。设计了2种缺口拉伸试样、3种缺口压缩试样,并结合相应的有限元模型分析,获取不同应力状态下材料的断裂应变、平均应力三轴度和平均罗德参数。以预测值和试验值的误差最小为目标,求解得到7075T73铝合金的Cockroft&Latham、Brozzo、Rice&Tracy三种韧性断裂准则参数,为7075T73铝合金高锁螺母收口成形工艺有限元仿真分析以及收口成形工艺优化提供理论支持。

关键词： 7075T73铝合金韧性断裂准则断裂应变材料参数

Mechanical behavior of underground pipe gallery structure considering ground fissure

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Journal of Mountain Science 2022年第2期19卷 547-562页

作者： deng bo-tuan LI Pan LI Xin TIAN Jiang-tao ZHI Bin School of Architecture and Civil Engineering Xi'an University of Science and TechnologyXi'an 710054China

The mechanical behavior of underground pipe gallery is a key research issue due to the static/dynamic states which exist in a ground fissure *** study took an underground pipe gallery project in Xi’an,China as the research *** analyzed the stress/strain characteristics of the pipe gallery structure and surrounding soil under static/dynamic conditions by the numerical simulation methods in *** on the results,we proposed a theoretical calculation model for the pipe gallery structure considering the influence of the ground fissure,and combined with engineering examples for calculation and *** results showed that:(1)the effective activity range of ground fissure on the deformation of the pipe gallery structure was mainly from 0.0 m(horizontal direction of ground fissure)to 32.0 *** activity range,the pipe gallery structure is prone to failure,owing to the large soil deformation in the vertical direction;(2)with the increase of ground fissure settlement,a stress reduction area near the ground fissure appeared at the bottom of the hanging wall of the pipe gallery structure,and a local void phenomenon was *** length of the local void is 6.0 m to 8.0 m under the maximum settlement(0.8 m)of the ground fissure;(3)Compared with the static conditions,the vertical and horizontal displacements of the pipe gallery structure and surrounding soil under the seismic action were little,and there were tensioncompression and torsion-shear effects in corner of the square pipe gallery structure(with a stress concentration phenomenon).The deformation law of pipe gallery structure and surrounding soil considering ground fissure and the theoretical model of pipe gallery structure established in this paper can provide reference for practical engineering.

关键词： Ground fissure Underground pipe gallery Finite element simulation Dynamic response Mechanical model

气顶边水油藏油气协同开发下流体界面运移特征

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科学技术与工程 2024年第17期24卷 7107-7113页

作者：邓博熊宇豪刘威谷建伟辛传奇吕柄辰中国石油大学(华东)石油工程学院青岛266580 天时集团能源有限公司盘锦124013 中国石油大学(北京)石油工程学院北京102249

气顶边水油藏的开发,存在明显的油气水互侵现象,导致产量快速递减,开发难度增大。为了防止生产井过早停产,需明确流体界面运移特征,制定油气协同开发生产制度。通过油藏数值模拟方法,建立了月东油田气顶边水油藏实际模型与机理模型,根... 详细信息

气顶边水油藏的开发,存在明显的油气水互侵现象,导致产量快速递减,开发难度增大。为了防止生产井过早停产,需明确流体界面运移特征,制定油气协同开发生产制度。通过油藏数值模拟方法,建立了月东油田气顶边水油藏实际模型与机理模型,根据气顶与边水作用能量强弱,将油气协同开发区域划分为边水控制区、气顶控制区和气顶边水联合控制区三类进行研究,综合评估气窜、水淹、油侵风险,明确油气、油水界面运移特征并形成运移速度图版。结果表明:随着开发的进行,气顶膨胀导致油气界面从油藏顶部向油井方向运移,边水侵入导致油水界面从油藏底部向油井与气井方向运移,油井存在气窜与水淹的风险,气井存在水淹与油侵的风险,剩余油主要分布在气顶下部和井间高部位,确定月东油田气顶边水油藏合理采气速度为6%~8%。基于实际与理论研究形成的成果认识为气顶边水油藏油气协同高效开发提供理论指导。

关键词：气顶边水油藏油气协同开发界面运移特征合理采气速度油藏数值模拟