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Mutations and intron polymorphisms in voltage-gated sodium channel genes of different geographic populations of Culex pipiens pallens/ Culex pipiens quinquefasciatus in China

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贫困所致传染病(英文) 2024年第2期13卷 1-11页

作者： Li Wenyu ma delong Mu Qunzheng Zhou Xinxin Hua Dongdong Zhao Chunchun Liu Qiyong Wang Jun Meng Fengxia State Key Laboratory of Infectious Disease Prevention and Control Department of Vector Biology and Control National Institute for Communicable Disease Control and Prevention Chinese Center for Disease Control and Prevention WHO Collaborating Centre for Vector Surveillance and Management Beijing People’s Republic of China Ningxia Center for Disease Prevention and Control YinChuan NingXia People’s Republic of China Jinan Shizhong Center for Disease Control and Prevention Jinan Shandong China Vanke School of Public Health Tsinghua University Beijing People’s Republic of China Weifang No. People’s Hospital Weifang Shandong People’s Republic of China Beijing Daxing Center for Disease Control and Prevention Beijing People’s Republic of China Jinan Second maternal and Child Health Hospital Jinan Shandong China

Background Culex pipiens pallens andCulex pipiens quinquefasciatus are the dominant species ofCulex mosquitoes in China and important disease vectors. Long-term use of insecticides can cause mutations in the voltage-gated sodium channel (vgsc) gene of mosquitoes, but little is known about the current status and evolutionary origins ofvgsc gene in different geographic populations. Therefore, this study aimed to determine the current status ofvgsc genes inCx. p. pallens andCx. p. quinquefasciatus in China and to investigate the evolutionary inheritance of neighboring downstream introns of thevgsc gene to determine the impact of insecticides on long-term evolution.Methods Sampling was conducted from July to September 2021 in representative habitats of 22 provincial-level administrative divisions in China. Genomic DNA was extracted from 1308 mosquitoes, the IIS6 fragment of thevgsc gene on the nerve cell membrane was amplified using polymerase chain reaction, and the sequence was used to evaluate allele frequency and knockdown resistance (kdr) frequency. MEGA 11 was used to construct neighborjoining (NJ) tree. PopART was used to build a TCS network.Results There were 6 alleles and 6 genotypes at the L1014 locus, which included the wild-type alleles TTA/L and CTA/L and the mutant alleles TTT/F, TTC/F, TCT/S and TCA/S. The geographic populations with akdr frequency less than 20.00% were mainly concentrated in the regions north of 38° N, and the geographic populations with akdr frequency greater than 80.00% were concentrated in the regions south of 30° N.kdr frequency increased with decreasing latitude. And within the same latitude, the frequency ofkdr in large cities is relatively high. Mutations were correlated with the number of introns. The mutant allele TCA/S has only one intron, the mutant allele TTT/F has three introns, and the wild-type allele TTA/L has 17 introns.Conclusions Cx. p. pallens andCx. p. quinquefasciatus have developed resistance to insecticides in most regions of China. The neighboring downstream i

关键词： Culex pipiens pallens Culex pipiens quinquefasciatus vgsc gene Mutation Frequency Intron Haplotype China

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促进基础设施投资引入民间资本

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宏观经济管理 2024年第2期 13-19页

作者：马德隆中央党校(国家行政学院)研究生院、中国宏观经济研究院综合运输研究所

民间资本参与基础设施建设投资可分为直接投资和间接投资。目前,我国民间资本直接投资参与建设项目仍显乏力,间接投资规模较小且多为“名股实债”。其原因是以隐性门槛为主的市场壁垒阻碍了民间资本进入,根源在于投融资模式的路径依赖... 详细信息

民间资本参与基础设施建设投资可分为直接投资和间接投资。目前,我国民间资本直接投资参与建设项目仍显乏力,间接投资规模较小且多为“名股实债”。其原因是以隐性门槛为主的市场壁垒阻碍了民间资本进入,根源在于投融资模式的路径依赖和建设运营自然垄断的泛化。对此,应瞄准资本、先易后难、市场为主、契合特性,以企项两端和金融创新推动民间资本间接投资,以先建机制和示范推广推动民间资本直接投资。

关键词：基础设施投资民间资本投融资改革

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Si-Based Anode materials for Li-Ion Batteries:A Mini Review

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Nano-Micro Letters 2014年第4期6卷 347-358页

作者： delong ma Zhanyi Cao Anming Hu Institute of Laser Engineering Beijing University of Technology 100 Pingle Yuan Key Laboratory of Automobile materials Ministry of Education and School of Materials Science and Engineering Jilin University Department of Mechanical Aerospace and Biomedical Engineering University of Tennessee

Si has been considered as one of the most attractive anode materials for Li-ion batteries(LIBs) because of its high gravimetric and volumetric capacity. Importantly, it is also abundant, cheap, and environmentally benign. In this review, we summarized the recent progress in developments of Si anode materials. First, the electrochemical reaction and failure are outlined, and then, we summarized various methods for improving the battery performance, including those of nanostructuring, alloying, forming hierarchic structures, and using suitable binders. We hope that this review can be of benefit to more intensive investigation of Si-based anode materials.

关键词： Li-ion batteries Anode Si High capacity Nanomaterials

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Self-standing rationally functionalized graphene as high-performance electrode materials for supercapacitors

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Journal of Energy Chemistry 2014年第3期23卷 346-353页

作者： delong ma Zhong Wu Zhanyi Cao Key Laboratory of Automobile materials Ministry of Educationand Department of Materials Science and EngineeringJilin University State Key Laboratory of Rare Earth Resource Utilization

Supercapacitors（SCs） have attracted much attention as one of the alternative energy devices due to their high power performance,long cycle life,and low maintenance cost.Graphene is considered as an innovative and promising material due to its large theoretical specific surface area,high electrical conductivity,good mechanical properties and chemical stability.Herein,we report an effective strategy for elaborately constructing rationally functionalized self-standing graphene（SG） obtained from giant graphene oxide（GGO） paper followed by an ultrarapid thermal-processing.This treatment results in both the exfoliation of graphene sheets and the reduction of GGO by elimination of oxygencontaining groups.The as-prepared SG electrode materials without additive and conducting agent provide an excellent combination of the electrical double layer capacitor（EDLC） and pseudocapacitor（PC） functions and exhibit superior electrochemical performance,including high specific capacitance,good rate capability and excellent cycling stability when investigated in three-electrode electrochemical cells.

关键词： functionalized graphene supercapacitors self-standing

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Laser-Assisted Reduction of Highly Conductive Circuits Based on Copper Nitrate for Flexible Printed Sensors

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Nano-Micro Letters 2017年第4期9卷 49-61页

作者： Shi Bai Shigang Zhang Weiping Zhou delong ma Ying ma Pooran Joshi Anming Hu Institute of Laser Engineering Beijing University of Technology School of Civil and Transportation Engineering Beijing University of Civil Engineering and Architecture Oak Ridge National Laboratory Department of Mechanical Aerospace and Biomedical Engineering University of Tennessee Knoxville

Stretchable electronic sensing devices are defining the path toward wearable electronics. High-performance flexible strain sensors attached on clothing or human skin are required for potential applications in the entertainment,health monitoring, and medical care sectors. In this work,conducting copper electrodes were fabricated onpolydimethylsiloxane as sensitive stretchable microsensors by integrating laser direct writing and transfer printing approaches. The copper electrode was reduced from copper salt using laser writing rather than the general approach of printing with pre-synthesized copper or copper oxide nanoparticles. An electrical resistivity of 96 l X cm was achieved on 40-lm-thick Cu electrodes on flexible substrates. The motion sensing functionality successfully demonstrated a high sensitivity and mechanical robustness.This in situ fabrication method leads to a path toward electronic devices on flexible substrates.

关键词： Laser direct writing Copper circuit Stretchable sensor Laser reduction

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Three-dimensionally macroporous graphene-supported Fe_3O_4 composite as anode material for Li-ion batteries with long cycling life and ultrahigh rate capability

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Chinese Science Bulletin 2014年第17期59卷 2017-2023页

作者： delong ma Shuang Yuan Zhanyi Cao Key Laboratory of Automobile materials of Ministry of Education School of Materials Science and EngineeringJilin University State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of Sciences

Fe3O4 is an attractive conversion reactionbased anode material with high theoretical capacity(928 ma h g-1).However,the poor cycling and rate performance hinder its applications in Li-ion batteries.In this work,we report an effective strategy to synthesize threedimensionally macroporous graphene-supported Fe3O4hybrid composite.Benefiting from advantage of the special structure,the hybrid composite exhibits excellent Li+ storage performance,delivering a high reversible capacity of980 ma h g-1at the current density of 4 A g-1even after470 cycles and ultrahigh rate capability(293 ma h g-1even at current density of 20 A g-1).

关键词：混杂复合材料锂离子电池四氧化三铁高速率循环寿命正极材料能力石墨

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Large-scale thrusting at the northern Junggar Basin since Cretaceous and its implications for the rejuvenation of the Central Asian Orogenic Belt

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Geoscience Frontiers 2015年第2期6卷 227-246页

作者： Jieyun Tang Dengfa He Di Li delong ma The Key Laboratory of marine Reservoir Evolution and Hydrocarbon Accumulation Mechanism The Ministry of EducationChina University of Geosciences (Beijing) Liaohe Oilfield Company China National Petroleum Corporation

The Wulungu Depression is the northernmost first-order tectonic unit in the Junggar Basin. It can be divided into three sub-units： the Hongyan step-fault zone, the Suosuoquan sag and the Wulungu south slope. The Cenozoic strata in the basin are intact and Mesozoic-Cenozoic deformation can be observed in the Wulungu step-fault zone, so this is an ideal place to study the Mesozoic-Cenozoic deformation. By integration of fault-related folding theories, regional geology and drilling data, the strata of the Cretaceous-Paleogene systems are divided into small layers which are selected as the subjects of this research. The combination of the developing unconformity with existing growth strata makes it conceivable that faults on the step-fault zone have experienced different degrees of reactivation of movement since the Cretaceous. Evolutionary analyses of the small layers using 2D-Move software showed certain differences in the reactivation of different segments of the Wulungu Depression such as the timing of reactivation of thrusting, for which the reactivity time of the eastern segment was late compared with those of the western and middle segments. In addition the resurrection strength was similarly slightly different, with the shortening rate being higher in the western segment than in the other segments. Moreover, the thrust fault mechanism is basement-involved combined with triangle shear fold, for which a forward evolution model was proposed.

关键词： Mesozoic-Cenozoic Thrust reactivity Wulungu depression Central Asian Orogenic Belt （CAOB）

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Kinematics of syn-tectonic unconformities and implications for the tectonic evolution of the Hala'alat Mountains at the northwestern margin of the Junggar Basin,Central Asian Orogenic Belt

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Geoscience Frontiers 2015年第2期6卷 247-264页

作者： delong ma Dengfa He Di Li Jieyun Tang Zheng Liu The Key Laboratory of marine Reservoir Evolution and Hydrocarbon Accumulation Mechanism The Ministry of Education China University of Geosciences Research Institute of Petroleum Exploration and Development-Northwest Petro China

The Hala＇alat Mountains are located at the transition between the West Junggar and the Junggar Basin. In this area, rocks are Carboniferous, with younger strata above them that have been identified through well data and high-resolution 3D seismic profiles. Among these strata, seven unconformities are observed and distributed at the bases of： the Permian Jiamuhe Formation, the Permian Fengcheng Formation, the Triassic Baikouquan Formation, the Jurassic Badaowan Formation, the Jurassic Xishanyao Formation, the Cretaceous Tugulu Group and the Paleogene. On the basis of balanced sections, these unconformities are determined to have been formed by erosion of uplifts or rotated fault blocks primarily during the Mesozoic and Cenozoic. In conjunction with the currently understood tectonic background of the sur- rounding areas, the following conclusions are proposed： the unconformities at the bases of the Permian Jiamuhe and Fengcheng formations are most likely related to the subduction and closure of the Junggar Ocean during the late Carboniferous-early Permian; the unconformities at the bases of the Triassic Baikoucluan and Jurassic Badaowan formations are closely related to the late Permian Triassic Durbut sinistral slip fault; the unconformities at the bases of the middle Jurassic Xisbanyao Formation and Cretaceous Tugulu Group may be related to reactivation of the Durbut dextral slip fault in the late Jurassic -early Cretaceous, and the unconformity that gives rise to the widely observed absence of the upper Cretaceous in the northern Junggar Basin may be closely related to large scale uplift. All of these geological phenomena indicate that the West Junggar was not calm in the Mesozoic and Cenozoic and that it experienced at least four periods of tectonic movement.

关键词： West Junggar The northwestern margin of the Junggar BasinSyn-tectonic unconformity Reconstruction of the CAOB

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Fe3O4-nanoparticle-decorated TiO2 nanofiber hierarchical heterostructures with improved lithium-ion battery performance over wide temperature range

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Nano Research 2015年第5期8卷 1659-1668页

作者： Hengguo Wang Guangsheng Wang Shuang Yuan delong ma Yang Li Yu Zhang Key Laboratory of Bio.lnspired Smart Interracial Science and Technology of Ministry of Education School of Chemistry and Enwronment Beihang University Beijing 100191 China School of materials Science and Engineering Changchun University of Science and Technology Changchun 130022 China State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China

灵巧的策略为 Fe 的制造被设计 3 O 4 -nanoparticle-decorated TiO 2 nanofiber 由联合 electrospinning 技术的通用性的层次 heterostructures ( FTH )并且热水的生长方法。Fe 的层次建筑学 3 O 在 TiO 上装饰的 4 nanopart... 详细信息

灵巧的策略为 Fe 的制造被设计 3 O 4 -nanoparticle-decorated TiO 2 nanofiber 由联合 electrospinning 技术的通用性的层次 heterostructures ( FTH )并且热水的生长方法。Fe 的层次建筑学 3 O 在 TiO 上装饰的 4 nanoparticles 2 nanofibers 启用进电池合成的二进制代码的成功的集成到地址结构的稳定性和低能力。在结果 FTH 的唯一的建筑学， 1D heterostructures 减轻 Fe 的严重的卷变化引起的紧张 3 O 4 在众多的费用分泌物周期期间，并且这样压制电极材料的降级。作为结果， FTH 包括更高可逆的能力显示出优秀性能，优秀周期生活，并且在由于 TiO 的二进制作文的 synergistic 效果的一个宽温度范围上的好率性能 2 和 Fe 3 O 4 和唯一的特征层次 nanofibers 。

关键词：锂离子电池异质结构纳米纤维温度范围氧化钛铁纳米粒子性能装饰

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Epidemiological characteristics and temporal-spatial analysis of overseas imported dengue fever cases in outbreak provinces of China, 2005–2019

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Infectious Diseases of Poverty 2022年第1期11卷 91-91页

作者： Xinchang Lun Yiguan Wang Chunchun Zhao Haixia Wu Caiying Zhu delong ma Mingfang Xu Jun Wang Qiyong Liu Lei Xu Fengxia Meng State Key Laboratory of Infectious Diseases Prevention and Control National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing102206People’s Republic of China 不详

Background Overseas imported dengue fever is an important factor in local outbreaks of this disease in the mainland of China.To better prevent and control such local outbreaks,the epidemiological characteristics and temporal-spatial distribution of overseas imported dengue fever cases in provincial-level administrative divisions(PLADs)where dengue fever is outbreak in the mainland of China were explored.Methods Using the Chinese National Notifiable Infectious Disease Reporting Information System(CNNDS),we identified overseas imported dengue fever cases in dengue fever outbreak areas in the mainland of China from 2005 to 2019 to draw the epidemic curve and population characteristic distribution of overseas imported cases in each PLAD.Based on spatial autocorrelation analysis of ArcGIS 10.5 and temporal-spatial scanning analysis of SaTScan 9.5,we analyzed the temporal-spatial distribution of overseas imported dengue fever in dengue fever outbreak areas in the mainland of China.Results A total of 11,407 imported cases,mainly from Southeast Asia,were recorded from 2005 to 2019 in these 13 PLADs.Of which 62.1%were imported into Yunnan and Guangdong Provinces.Among the imported cases,there were more males than females,mainly from the 21–50 age group.The hot spots were concentrated in parts of Yunnan,Guangdong and Fujian Provinces.We found the cluster of infected areas were expanding northward.Conclusions Based on the analysis of overseas imported dengue cases in 13 PLADs of the mainland of China from 2005 to 2019,we obtained the epidemiological characteristics and spatial distribution of imported dengue cases.Border controls need to pay attention to key population sectors,such as 21–50 years old men and education of key populations on dengue prevention.There is a need to improve the awareness of the prevention and control of imported cases in border areas.At the same time,northern regions cannot relax their vigilance.

关键词： Imported case Dengue fever China Epidemiology Temporal-spatial distribution

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