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国内观鸟旅游研究综述

河北旅游职业学院学报 2019年第1期24卷 33-38页

作者：肖乾丽杨建美 deepa Basnet 岳茂伟西南林业大学地理学院昆明650224 ICIMOD 西南林业大学生态旅游学院昆明650224 不详

观鸟旅游作为生态旅游的一种重要表现形式,对经济、社会、环境保护等具有重要意义。随着观鸟旅游的发展,国内观鸟旅游的研究逐渐增多。文章整理了国内观鸟旅游研究文献,经过筛选确定了97篇文章作为研究对象,采用定量与定性研究结合的方... 详细信息

观鸟旅游作为生态旅游的一种重要表现形式,对经济、社会、环境保护等具有重要意义。随着观鸟旅游的发展,国内观鸟旅游的研究逐渐增多。文章整理了国内观鸟旅游研究文献,经过筛选确定了97篇文章作为研究对象,采用定量与定性研究结合的方式,总结了国内观鸟旅游的研究内容和方向。资源分析与旅游开发是国内观鸟旅游研究的重要内容,观鸟者行为研究、观鸟教育、观鸟旅游发展对策分析在观鸟旅游研究中也涉及较多,观鸟旅游的研究在不同方面存在较大差异性,以及地域空白性。加强观鸟旅游的研究,弥补地域空白性对观鸟旅游的发展有重要意义,文章在综述分析的基础上,预测了观鸟旅游的发展方向和研究趋势。

关键词：观鸟旅游国内研究综述研究趋势

Isolation and Characterization of Contaminating Bacteria from Garcinia cambogia Extract: Methods to Reduce Microbial Load and Its Anti-Obesity Effect in Wistar Rats

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Natural Resources 2022年第7期13卷 147-170页

作者： Raj Kumar Bhosale Sasidharan Sakkan Srinivasa Murthy Venkatramanappa Shivaswamy Mathada Rudraiah Kumaraswamy Rampur Arulmozhi Sathiyanarayanan deepa Mandlik Sanman Kolhe Sadanand Yewale Sriram Padmanabhan Herbal Division Sava Healthcare Limited Research Center MIDC Chinchwad India QC Division Sava Healthcare Limited KIADB Malur India Production Team Sava Healthcare Limited KIADB Malur India Department of Pharmacology Poona College of Pharmacy Bharati Vidyapeeth (Deemed to Be University) Pune India SAVA Healthcare Limited Research Center Pune India

Objectives: This study aimed to identify the contaminating bacteria in the extract of Garcinia cambogia, which is regularly used as a dietary supplement for addressing obesity in humans. Methods: The Garcinia cambogia extract was used and experiments were conducted to isolate the contaminating bacteria and antibiotic susceptibility was tested. The organism was identified using BIOLOG system. Such an extract was used in a placebo-controlled animal study when 6 eight adult male rats weighing between 200 and 220 g were randomly distributed into three groups (n = 3) and in test group 1, a single dose of 100 mg/kg bw of Garcinia cambogia extract was given while in the test group 2, 100 mg Garcinia cambogia extract + 116 mg Picrorhiza kurroa extract were administered through oral gavage. The normal control rats were given distilled water, and the treatment lasted for 30 days. Blood plasma and liver tissues were prepared for biochemical analysis and histology studies. Results: Nearly ~103 cfu/g of Bacillus atrophaeus was present in the Garcinia cambogia extract and we demonstrate >99% reduction in the microbial load with tetracycline. Such an extract at a dose of 100 mg/kg, showed weight loss in Wistar rats when administered orally for 1 month with no significant changes in liver histopathology. Picrorhiza kurroa, also known for its hepatoprotective properties, has been administered at a dose of 116 mg/kg along with Garcinia extract at 100 mg/kg orally and found to improve levels of hepatic enzymes as similar to control animals, although not statistically significant. Conclusions: The study revealed that Garcinia cambogia could prevent weight gain in Wistar rats when given orally and the weight gain in Garcinia-treated animals was almost 4 times less (7.31%), as against weight gain of 25.36% seen in vehicle control animals. The antibiotic susceptibility data indicated that the isolated bacterium is resistant to many antibiotics with a strong susceptibility to te

关键词： Garcinia cambogia Hydroxy Citric Acid Picrorhiza kurroa Liver Health ATP Citrate Lyase

Association between acute peripancreatic fluid collections and early readmission in acute pancreatitis:A propensity-matched analysis

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World Journal of Experimental Medicine 2024年第2期14卷 75-88页

作者： Hassam Ali Faisal Inayat Waqas Rasheed Arslan Afzal Ahtshamullah Chaudhry Pratik Patel Attiq Ur Rehman Muhammad Sajeel Anwar Gul Nawaz Muhammad Sohaib Afzal Amir H Sohail Subanandhini Subramanium Dushyant Singh Dahiya deepa Budh Babu P Mohan Douglas G Adler Department of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Internal Medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Department of Internal Medicine Texas Tech University Health Sciences CenterLubbockTX 79430United States Department of Internal Medicine St.Dominic’s HospitalJacksonMS 39216United States Department of Gastroenterology Mather Hospital and Hofstra University Zucker School of MedicinePort JeffersonNY 11777United States Department of Hepatology Geisinger Wyoming Valley Medical CenterWilkes-BarrePA 18711United States Department of Internal Medicine UHS Wilson Medical CenterJohnson CityNY 13790United States Department of Internal Medicine Louisiana State University HealthShreveportLA 71103United States Department of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States Division of Gastroenterology Hepatologyand MotilityThe University of Kansas School of MedicineKansas CityKS 64108United States Department of Internal Medicine St.Barnabas Hospital and Albert Einstein College of MedicineBronxNY 10457United States Department of Gastroenterology and Hepatology University of Utah School of MedicineSalt Lake CityUT 84132United States Center for Advanced Therapeutic Endoscopy Porter Adventist HospitalCentura HealthDenverCO 80210United States

BACKGROUND Patients with acute pancreatitis(AP)frequently experience hospital readmissions,posing a significant burden to healthcare *** peripancreatic fluid collection(APFC)may negatively impact the clinical course of *** could worsen symptoms and potentially lead to additional ***,clinical evidence regarding the specific association between APFC and early readmission in AP remains *** the link between APFC and readmission may help improve clinical care for AP patients and reduce healthcare *** To evaluate the association between APFC and 30-day readmission in patients with *** This retrospective cohort study is based on the Nationwide Readmission Database for *** with a primary diagnosis of AP were *** were categorized into those with and without APFC.A 1:1 propensity score matching for age,gender,and Elixhauser comorbidities was *** primary outcome was early readmission *** outcomes included the incidence of inpatient complications and healthcare *** analyses used Mann-Whitney U andχ2 tests,while Cox regression models assessed 30-day readmission risks and reported them as adjusted hazard ratios(aHR).Kaplan-Meier curves and log-rank tests verified readmission *** A total of 673059 patients with the principal diagnosis of AP were *** these,5.1%had APFC on initial *** propensity score matching,each cohort consisted of 33914 *** with APFC showed a higher incidence of inpatient complications,including septic shock(3.1%vs 1.3%,P<0.001),portal venous thrombosis(4.4%vs 0.8%,P<0.001),and mechanical ventilation(1.8%vs 0.9%,P<0.001).The length of stay(LOS)was longer for APFC patients[4(3-7)vs 3(2-5)days,P<0.001],as were hospital charges($29451 vs$24418,P<0.001).For 30-day readmissions,APFC patients had a higher rate(15.7%vs 6.5%,P<0.001)and a longer median readmission LOS(4 vs 3 days,P<0.001).The APF

关键词： Acute pancreatitis Acute peripancreatic fluid collections Readmission predictors Inpatient complications Healthcare utilization and costs

Fasting C-Peptide Response, and Its Clinical Impact in Type I Diabetics to a Novel Metaphysical Energy Healing Therapy—Preliminary Experience and Observations

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Journal of Diabetes Mellitus 2016年第1期6卷 90-99页

作者： C. V. Krishnaswami Ramesh Chandrasekaran deepa Krishnaswami A. Ganesan B. Sampoornam Saroja Srinivasan A. Srivasta Shobana Anojan V. Rajan Iyer TAG-VHS Diabetes Research Centre (A Unit of Voluntary Health Services Diabetes Department) Chennai India

Type 1 diabetes is classically the true form of insulinopaenic diabetes usually occurring in young children below the age of 15 years and occasionally up to 20 years and characterised by very low/ negligible fasting C-peptide in their blood due to extensive irreversible Beta cell damage. T1DM probably accounts for 5% to 10% of all diagnosed diabetes. The worldwide prevalence of T1DM is 0.1% to 0.3%, with 78,000 new cases every year, especially among young individuals (15. Type I diabetes is very much lower (20 times) in countries like Japan and India, than the western countries. The European Nicotinamide Diabetes Intervention Trial (ENDIT) is focused on the use of nicotinamide in the prevention of diabetes. In high doses (nicotinamide), it may cause a degree of sedation, a feeling of depression, and in very large dosages, liver toxicity. Because the vitamin cannot be marketed as a drug, the study is not getting a great deal of support from pharmaceutical companies. GAD antibodies (GADA) are a major diagnostic marker for Type 1 diabetes. Phase II clinical trials of a vaccine containing alum and recombinant GAD65, an auto antigen involved in type 1 diabetes, were promising, as of 2014 Phase III trial had failed. In our quest for improving the clinical condition & quality of life of type I DM & also to reduce the economic burden on them, we have embarked on a novel metaphysical energy therapy which we have been trying for the past 3 years at our research Centre. We have so far treated some 15 cases with this DAMM therapy. Among the 15 cases, 6 cases have shown significant improvement in fasting C-peptide levels. With the advent of this new modality of treatment (DAMM Therapy) the cost of treatment will be greatly reduced. This DAMM Therapy apparently has no side effects. This mode of treatment will open a new light in the world of Type I diabetes.

关键词： J.I.I.D.M. T1DM IDDM ENDIT GAD65 GADA DAMM Therapy

支点弯曲位X线片对运用椎弓根螺钉固定治疗脊柱侧凸中的可预测性

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中华骨科杂志 2010年第6期30卷 I0037-I0042页

作者： Kenneth M.C. Cheung deepa Natarajan Dino Samartzis Yat-Wa Wong Wai-Yuen Cheung Keith D.K. Luk 宋跃明(译) Investigation performed at the Department of Orthopaedics arid Traumatology Duchess of Kent Children's Hospital Hong Kong China 四川大学华西医院骨科 610041

背景：支点弯曲位X线片在运用钩棒系统治疗青少年特发性脊柱侧凸时能准确预测术后弯曲矫正情况。本研究拟探讨支点弯曲位x线片在运用交替椎弓根螺钉固定治疗脊柱侧凸中的预测性价值。方法：我们对在同一机构内运用交替椎弓根螺钉固定方... 详细信息

背景：支点弯曲位X线片在运用钩棒系统治疗青少年特发性脊柱侧凸时能准确预测术后弯曲矫正情况。本研究拟探讨支点弯曲位x线片在运用交替椎弓根螺钉固定治疗脊柱侧凸中的预测性价值。方法：我们对在同一机构内运用交替椎弓根螺钉固定方法进行手术治疗的胸椎特发性脊柱侧凸患者进行前瞻性放射学分析。测量术前和术后1周时站立后前位脊柱x线片上侧凸的Cobb角。计算支点柔韧百分比和支点弯曲矫正指数百分比。结果：42例患者纳入本研究。实施手术时患者的平均年龄是14．6岁，平均融合节段数为9．4个。术前站立位X线片Cobb角、支点弯曲位Cobb角、支点柔韧度分别为57．9°．21．8°和62．7％。术后1周X线片，平均Cobb角为15．4°，弯曲的平均矫正度为73.4％，支点弯曲的平均矫正指数为122．1％。支点弯曲位x线片的角度与支点弯曲矫正指数呈显著正相关，表明支点弯曲化X线片能预测支点弯曲的术后矫正情况。然而，对于僵硬型的脊柱侧凸，椎弓根螺钉固定能为患者带来比支点弯曲位X线片所预测的更理想的矫正效果。结论：据我们所知，本研究是证实支点弯曲位X线片在运用交替椎弓根螺钉固定治疗脊柱侧凸中的预测性价值的首次研究。弯曲的柔韧性能反映支点弯曲矫正指数的程度，即柔韧性差的侧凸畸形能获得一个更大的矫正指数。支点弯曲位x线片具有潜在的预测价值。此外．与钩棒及其他系统相比，椎弓根螺钉固定表现出更好的矫正能力。

关键词：青少年特发性脊柱侧凸椎弓根螺钉固定支点弯曲位可预测性固定治疗 X线片 Cobb角预测价值

Predictive modelling for COVID-19 outbreak control:lessons from the navy cluster in Sri Lanka

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Military Medical Research 2022年第1期9卷 138-140页

作者： N.W.A.N.Y.Wijesekara Nayomi Herath K.A.L.C.Kodituwakku H.D.B.Herath Samitha Ginige Thilanga Ruwanpathirana Manjula Kariyawasam Sudath Samaraweera Anuruddha Herath Senarupa Jayawardena deepa Gamge Disaster Preparedness and Response Division Ministry of Health385Rev.Baddegama Wimalawansa Thero MawathaColombo 01000Sri Lanka Epidemiology Unit of the Ministry of Health Colombo 01000Sri Lanka Sri Lanka Navy Colombo 01100Sri Lanka

In response to an outbreak of coronavirus disease 2019(COVID-19)within a cluster of Navy personnel in Sri Lanka commencing from 22nd April 2020,an aggressive outbreak management program was launched by the Epidemiology Unit of the Ministry of *** predict the possible number of cases within the susceptible population under four social distancing scenarios,the COVID-19 Hospital Impact Model for Epidemics(CHIME)was *** increasing social distancing,the epidemiological curve flattened,and its peak shifted to the *** observed or actually reported number of cases was above the projected number of cases at the onset;however,subsequently,it fell below all predicted *** modelling is a useful tool for the control of outbreaks such as COVID-19 in a closed community.

关键词： COVID-19 Predictive modelling SIR model Navy cluster Outbreak management

中国实生和无性系苹果砧木及其杂交后代矮化基因型分子鉴定

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果树学报 2020年第12期37卷 1779-1786页

作者：张恒涛 BUS Vincent G.M. 张亚茹王欢王美丽 BOWATTE deepa GARDINER Susan E. CHAGNE David KIRK Chris KUMAR Satish 王大江张瑞萍周喆 YAO Jia-Long 阎振立中国农业科学院郑州果树研究所郑州450009 新西兰皇家植物与食品研究院 Havelock North 4157新西兰新西兰皇家植物与食品研究院 Palmerston North 4442新西兰中国农业科学院果树研究所辽宁兴城125100 新西兰皇家植物与食品研究院 Auckland 1142新西兰

【目的】利用已开发的矮化性状分子标记(Dw1/Dw2)筛选中国实生和自育无性系苹果砧木,探明各个砧木品种的矮化基因型,为苹果砧木育种工作中亲本选择及矮化分子辅助育种提供帮助。【方法】以不同地区采集的24份中国实生和自育的无性系苹... 详细信息

【目的】利用已开发的矮化性状分子标记(Dw1/Dw2)筛选中国实生和自育无性系苹果砧木,探明各个砧木品种的矮化基因型,为苹果砧木育种工作中亲本选择及矮化分子辅助育种提供帮助。【方法】以不同地区采集的24份中国实生和自育的无性系苹果砧木、147份新疆野苹果(李2-3)×‘M9’和345份山荆子(野1-2)×‘M9’杂交后代单株的叶片DNA为模板,以矮化砧木‘M9’‘M116’和‘MM106’为对照,利用已经开发的Dw1和Dw2矮化标记的SSR引物进行PCR扩增,然后用毛细管电泳检测PCR产物,分析确定各个样品的矮化基因型。【结果】在24份中国苹果砧木中鉴定出8份携带Dw1矮化基因,5份携带Dw2矮化基因,3个自育杂交品种同时携带Dw1和Dw2矮化基因;新疆野苹果(李2-3)×‘M9’组合的147个杂种实生苗中有48株携带Dw1矮化基因,14株同时携带Dw1和Dw2基因,山荆子(野1-2)×‘M9’的345个杂交后代中仅有11个单株携带Dw1基因型,其余单株均不携带任一矮化基因。【结论】试验中检测的八棱海棠(房2-3)、山荆子(野1-2)和平邑甜茶(野2-22)等中国常用实生砧木均不携带Dw1或Dw2基因,仅新疆野苹果(李2-3)中含有Dw2矮化基因;中国自育的杂交砧木品种中,以‘M9’等矮化品种为亲本的后代大多携带Dw1或Dw2;双亲都含有矮化基因的杂交组合后代能获得更多的携带矮化基因的单株。

关键词：苹果砧木矮化性状基因型分子标记育种

Mre11-Rad50-Nbs复合物在果蝇胚胎发育早期参与端粒的保护

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Mre11-Rad50-Nbs复合物在果蝇胚胎发育早期参与端粒的保护

Mre11-Rad50-Nbs复合物在果蝇胚胎发育早期参与端粒的保护

第十一次中国生物物理学术大会暨第九届全国会员代表大会

作者： Xiaolin Bi Guanjun Gao Jie Chen deepa Srikanta Yikang Rong Key Laboratory for Biological Effects of Nanomaterials and Nanosafety Lab of Molecular Cell Biology

＜正＞应用果蝇模式生物系统,我们发现在胚胎发育早期,端粒的保护依赖于Mre11-Rad50-Nbs（MRN）复合物。发生mre11或nbs减效基因突变的纯合动物能够正

关键词： mre11-rad50-nbs1 端粒胚胎发育母系致死

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生物物理学报 2009年第S1期25卷 93-93页

作者： Xiaolin Bi Guanjun Gao Jie Chen deepa Srikanta Yikang Rong Key Laboratory for Biological Effects of Nanomaterials and Nanosafety IHEPCAS Lab of Molecular Cell Biology NCINIHBethesdaMDUSA

应用果蝇模式生物系统,我们发现在胚胎发育早期,端粒的保护依赖于Mre11-Rad50-Nbs(MRN)复合物。

关键词： mre11-rad50-nbs1 端粒胚胎发育母系致死