检索结果-南通市图书馆

Tau's function and dysfunction in the brain:when small changes have big consequences

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第1期19卷 152-153页

作者： Miguel Portillo debra Toiber Department of Life Sciences Ben-Gurion University of the NegevBeer ShevaIsraelThe Zlotowski Center for NeuroscienceBen-Gurion University of the NegevBeer ShevaIsrael

With the increase of life expectancy and population growth,neurodegenerative diseases have risen too and are projected to be a major health public concern by *** diseases are characterized by the progressive decline of cognitive function leading to the subsequent loss of *** the underlying causes of neurodegeneration are not well understood,aging is the main risk factor.

关键词： diseases consequences function

Microglial dysfunction and genetic risk for neurodegenerative disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第5期20卷 1401-1402页

作者： debra S.MacDonald Jay Penney Department of Biomedical Sciences AVCUniversity of Prince Edward IslandCharlottetownPECanada

Neurodegenerative disorders such as Alzheimer's and Parkinson's diseases a re increasing in prevalence as world populations *** tremendous progress has been made,our understanding of the mechanisms that underlie the development of these diseases remains far from com *** troubling,despite the growing emotional and financial toll being to ken by neurodegenerative disorders,existing treatment options are limited almost exclusively to those that help manage symptoms but that lack the ability to alter the progression of the disease(Liu et al.,2022).

关键词： degenerative diseases

在线全文

学校读者我要写书评

暂无评论

沟通不畅,害你损失

空中英语教室（高级版．彭蒙惠英语） 2024年第5期 10-11,39,40页

作者： debra Roberts 不详

沟通技巧如何影响你的盈亏?根据Grammarly公司2022年的商务沟通状态显示,商业领袖评估职场沟通不畅会造成平均每名员工每周浪费7.47小时。“团队里的全职知识工作者据估平均年薪为66976美元,每周浪费7.47小时相当于每年每名员工12506美... 详细信息

沟通技巧如何影响你的盈亏?根据Grammarly公司2022年的商务沟通状态显示,商业领袖评估职场沟通不畅会造成平均每名员工每周浪费7.47小时。“团队里的全职知识工作者据估平均年薪为66976美元,每周浪费7.47小时相当于每年每名员工12506美元的沉没成本。”组织内部沟通不畅是由许多因素造成的。财务损失的程度取决于这个问题的广度与深度、问题未得到解决的时长,以及该问题对别人造成何种影响。

关键词：商业领袖沉没成本财务损失商务沟通知识工作者状态显示沟通技巧组织内部沟通

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

为什么人们在洗澡时唱歌?

中学生英语 2024年第3期 29-31页

作者： debra Ronca 笃景行(译) 不详

浴室里的每个人都是摇滚明星。承认吧。你在生活中有过一两次在洗澡时抓住淋浴喷头突然唱出一两首曲子的情况。洗澡时唱歌有一种完全令人满意的感觉。

关键词：淋浴喷头唱歌浴室

Gene bank scheduling of seed regeneration: Interim report on a long term storage study

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2019年第7期18卷 1529-1540页

作者： Robert Redden debra Partington Australian Temperate Field Crops Collection Private Bag 260Agriculture Victoria

A major challenge for the management of gene banks is the maintenance of good seed health in the *** germplasm collections >10 000 accessions often have been acquired from different sources over a range of dates,may differ in germination at time of deposition in the gene bank,and may have genetic differences in seed *** major storage variables affecting seed longevity are temperature and seed moisture *** varieties of each pea(Pisum sativus L.),lentil(Lens culinaris Medikus ***),and chickpea(Cicer arietinum L.),were stored at three temperatures;40,20,and 2°C,each with three seed moisture levels of 10.9–13.8%(high),7.9–10.3%(medium),and 7–7.8%(low),in the Australian Temperate Field Crops Collection gene *** longevity at a given storage period was estimated by the corresponding germination percentage for each *** paper is an interim report on seed viability decline in the first seven years of this seed longevity study,in which viability decline towards zero was almost completed in the three seed moisture treatments at 40°C and the 20°C high seed moisture treatment,but had not declined in the other *** longevity positively responded to a reduction in temperature and then to a reduction in seed *** number of days in storage for seed germination decline to 85%(p85),and to 50%(p50) for mean seed viability,are reported by storage/varietal *** p85 and p50 showed significant inverse linear responses with seed moisture at 40°C for pea and lentil varieties,with intra-specific variation for *** long term trial aims to provide informed timing of seed regeneration for accessions in a gene bank.

关键词： gene bank storage moisture level temperature regeneration pea lentil chickpea

Control of hydrogen sulfide emissions using autotrophic denitrification landfill biocovers:engineering applications

在线全文

学校读者我要写书评

暂无评论

Frontiers of Environmental Science & Engineering 2011年第2期5卷 149-158页

作者： Daoroong SUNGTHONG debra R.REINHART Department of Environmental Science Faculty of ScienceSilpakorn UniversityNakhon Pathom73000Thailand Civil Environmental and Construction Engineering DepartmentUniversity of Central FloridaOrlandoFL 32826USA

Hydrogen sulfide(H_(2)S)emitted from construction and demolition waste landfills has received increasing *** its unpleasant odor,longterm exposure to a very low concentration of H_(2)S can cause a public health *** the case of construction and demolition(C&D)waste landfills,where gas collection systems are not normally required,the generated H_(2)S is typically not controlled and the number of treatment processes to control H_(2)S emissions in situ is *** attractive alternative may be to use chemically or biologically active landfill covers.A few studies using various types of cover materials to attenuate H_(2)S emissions demonstrated that H_(2)S emissions can be effectively *** this study,therefore,the costs and benefits of H_(2)S-control cover systems including compost,soil amended with lime,fine concrete,and autotrophic denitrification were *** on a case-study landfill area of 0.04 km^(2),the estimated H_(2)S emissions of 80900 kg over the 15-year period and costs of active cover system components(ammonium nitrate fertilizer for autotrophic denitrification cover,lime,fine concrete,and compost),ammonium nitrate fertilizer is the most cost effective,followed by hydrated lime,fine concrete,and yard waste *** concrete and yard waste compost covers are expensive measures to control H_(2)S emissions because of the large amount of materials needed to create a *** H_(2)S emissions using fine concrete and compost is less expensive at landfills that provide on-site concrete recovery and composting facilities;however,ammonium nitrate fertilizer or hydrated lime would still be more cost effective applications.

关键词： hydrogen sulfide emissions construction and demolition waste autotrophic denitrification landfill biocovers

DNA damage and neurodegeneration:the unusual suspect

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2017年第9期12卷 1441-1442页

作者： Daniel Stein debra Toiber Department of Life Sciences Ben-Gurion University of the Negev The Zlotowski Center for Neuroscience Ben-Gurion University of the Negev

Neurodegenerative diseases are caused by the loss of neuro- nal cells. As neurons deteriorate, a patient may experience relatively mild symptoms such as failing to name objects and people. However, with the progression of the disease, symp- toms worsen resulting in loss of independence and a sense of＂loss of oneself＂. Finally, the patient dies from a variety of complications.

关键词： DNA damage and neurodegeneration:the unusual suspect

在线全文

学校读者我要写书评

暂无评论

杀人鸟鹤鸵地球上最后的恐龙？

环球人文地理 2024年第9期 70-77页

作者：鲨鲨 ms＿pics＿and＿more luismicss SALTY RIVER karegg Arjan diegograndi wagner＿md Adam debra electra kay-smith Zorro Stock images

科学研究表明，这种能吞火炭，能杀人，得到过吉尼斯世界纪录认证的大鸟，也许是地球上最后的恐龙。6500万年前，恐龙的足迹终结在那场白垩纪-古近纪灭绝事件中，斗转星移，其中的一部分生物进化至今，演变成了近万种鸟类。鹤鸵就是其...

科学研究表明，这种能吞火炭，能杀人，得到过吉尼斯世界纪录认证的大鸟，也许是地球上最后的恐龙。6500万年前，恐龙的足迹终结在那场白垩纪-古近纪灭绝事件中，斗转星移，其中的一部分生物进化至今，演变成了近万种鸟类。鹤鸵就是其中一种。它们生活在巴布亚新几内亚森林深处，就像恐龙世界最后的碎片。

关键词：

Pathologic pancreatic endocrine cell hyperplasia

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2011年第2期17卷 137-143页

作者： debra Ouyang Deepti Dhall Run Yu Department of Medicine Cedars-Sinai Medi-cal Center Los Angeles CA 90048 United States Department of Pathology Cedars-Sinai MedicalCenter Los Angeles CA 90048 United States Division of Endocrinology and Carcinoid and Neu-roendocrine Tumor Center Cedars-Sinai Medical Center LosAngeles CA 90048 United States

Pathologic hyperplasia of various pancreatic endocrine cells is rare but has been long known.β cell hyperplasia contributes to persistent hyperinsulinemic hypoglycemia of infancy,which is commonly caused by mutations in the islet ATP-sensitive potassium channel,and to noninsulinoma pancreatogenous hypoglycemia in adults,which may or may not be associated with bariatric surgery.α cell hyperplasia may cause glucagonoma syndrome or induce pancreatic neuroendocrine *** inactivating mutation of the glucagon receptor causes α cell hyperplasia and asymptomatic *** polypeptide cell hyperplasia has been described without a clearly-characterized clinical syndrome and hyperplasia of other endocrine cells inside the pancreas has not been reported to our knowledge. Based on morphological evidence,the main pathogenetic mechanism for pancreatic endocrine cell hyperplasia is increased endocrine cell neogenesis from exocrine ductal *** endocrine cell hyperplasia should be considered in the diagnosis and management of hypoglycemia,elevated islet hormone levels,and pancreatic neuroendocrine *** studies of pathologic pancreatic endocrine cell hyperplasia will likely yield insights into the pathogenesis and treatment of diabetes and pancreatic neuroendocrine tumors.

关键词： Glucagon receptor Hyperplasia Nesidioblastosis Islet Pancreatic endocrine cell Neuroendocrine tumor