检索结果-南通市图书馆

Comparative analysis of DNA-SIP and magnetic-nanoparticle mediated isolation (MMI) on unraveling dimethoate degraders

在线全文

学校读者我要写书评

暂无评论

Frontiers of Environmental science & Engineering 2024年第1期18卷 59-69页

作者： Luning Lian Yi Xing dayi Zhang Longfei Jiang Mengke Song Bo Jiang School of Energy and Environmental Engineering University of Science&Technology BeijingBeijing 100083China beijing Key Laboratory of Resource-oriented Treatment of Industrial Pollutants University of Science&Technology BeijingBeijing 100083China National Environmental and Energy science and technology International Cooperation Base University of Science&Technology BeijingBeijing 100083China College of New Energy and Environment Jilin UniversityChangchun 130021China Guangzhou Institute of Geochemistry Chinese Academy of SciencesGuangzhou 510640China College of Natural Resources and Environment South China Agricultural UniversityGuangzhou 510642China National Engineering Laboratory for Site Remediation Technologies Beijing 100015China

Microorganisms are crucial in the bioremediation of organophosphorus pesticides. However, most functional microorganisms (> 99%) are yet to be cultivated. This study applied two cultivation-independent approaches, DNA-SIP and magnetic-nanoparticle mediated isolation (MMI), to identify the functional microorganisms in degrading dimethoate in agricultural soils. MMI identified five dimethoate degraders: Pseudomonas, Bacillus, Ramlibacter, Arthrobacter, and Rhodococcus, whereas DNA-SIP identified three dimethoate degraders: Ramlibacter, Arthrobacter, and Rhodococcus. Also, MMI showed higher resolution than DNA-SIP in identifying functional microorganisms. Two organic phosphohydrolase (OPH) genes: ophC2 and ophB, were involved in dimethoate metabolism, as revealed by DNA-SIP and MMI. The degradation products of dimethoate include omethoate, O,O,S-trimethyl thiophosphorothioate, N-methyl-2-sulfanylacetamide, O,O-diethyl S-hydrogen phosphorodithioate, O,O,O-trimethyl thiophosphate, O,O,S-trimethyl thiophosphorodithioate, and O,O,O-trimethyl phosphoric. This study emphasizes the feasibility of using SIP and MMI to explore the functional dimethoate degraders, expanding our knowledge of microbial resources with cultivation-independent approaches.

关键词： Stable isotope probing(SIP) Magnetic-nanoparticle mediated isolation(MMI) Dimethoate Biodegradation Cultivation-independent approach

Fluid Inclusions and Daughter Minerals of Taibai Gold Deposit, ShaanXi Province, china

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of university of science and technology beijing 2001年第1期8卷 6-9页

作者： YulingXie, Jiuhua Xu, dayi qian, Jianping Li Resources Engeneering School, university of science and technology beijing, beijing 100083. china Resources Engeneering School Univ. of Science/Technology Beijing Beijing 100083 China

A discovery of daughter minerals in fluid inclusions of Taibai gold deposit, Shaanxi province has been focused on, which is a unique breccia-cemented gold-bearing system. The breccia zone strikes NWW-SEE, occurring in Devonian strata of Southern Qinling Mountains. The cement is mainly composed of ankerite, pyrite, calcite and quartz, which may be divided into four main tectonic-mineralizing stages. Gold mainly occurs in pyrite and ankerite of stage II and IV. It is found that three types of fluid inclusions can be distinguished: (1) aqueous inclusions (type B); (2) CO2-rich inclusions (type C); (3) daughter minerals-containing inclusions (type A). LRM. (Laser Raman Micro-probe) analyses shows that the content of CO2 occupies 54.4%-70.7% (mole fraction, so as the follows) in vapor phases of different type fluid inclusions. CH4 (5.2%-7.3%) and H2S (6.0%-12.7%) exist in both vapor and liquid phases. Many daughter minerals in fluid inclusions of ankerite and quartz have been found. Several kinds of daughter minerals, including ankerite, pyrite, arsenopyrite and halite, were determined by using SEM (scanning electron microscope)/EDS (energy dispersive spectrometer) technique. EPMA (electron probe micro-analysis) technique was also applied to study the daughter minerals exposed to the surface of polished thin sections.

关键词： daughter minerals fluid inclusions gold deposit breccia

Characteristics of Ore-Forming Fluids of Gold Deposits in Daqingshan District,Inner Mongolia,china

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 1999年第2期13卷 77-82页

作者： Jiuhua Xu YulingXie dayi qian Rufu Dine Jianping Li (Resource Engineering School, university of science and technology Beijha beijing 100083. china) (china university of Geosciences, beijing 100083. china) Resource Engineering School University of Science and Technology Beijing Beijing 100083 China china university of Geosciences Beijing 100083 China

***-weststrikingductileshearzonewithinagreelt,***:(1)pyrite-quartz,(2)quartz-Pyrite,(3)polymetallicsulfidesand(4)***-bearingveinsarenativegold,electrum,pyrite,chalcopyriteandgalena,buttheganguemineralsaremainlyquartz,secondarilysericite,***,silicification,***-formingfluidswerelowinsalinitieandhighinCO2content,MeasuredδDoffluidinclusionsinquartzfromtheoreveinsrangesfrom-65‰to-104‰,butδ18Oquartzfrom10.0‰to12.8‰.Thesedatashowthatthewaterinhydrothermalfluidprecipitatingtheorebodiescouldhavebeenmainlymagmaticwaterandmetamorphicwaterbutlocalmeteoricwatermighttakepartinthelatemineralization.δ13Cfromfl

关键词： fluid inclusions isotope composition gold deposit Daqingshan area

Study on Sulfide-melt Inclusions in Mantle Xenoliths of Xinchang, Zhejiang

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2000年第1期14卷 5-9页

作者： Jiuhua Xu Xuelei Chu YulingXie Fenglei Bie dayi qian university of science and technology beijing, beijing 100083. china china university of Geosciences, beijing 100083. china The Research Center of Mineral Resources Exploration, Chinese Academy university of science and technology beijing Beijing 100083 China Research Center of Mineral Resources Exploration Chinese Academy of Sciences Beijing 100101 China Institute of Geology Chinese Academy of Sciences Beijing 100029 China china university of Geosciences Beijing 100083 China

In minerals of mantle xenoliths captured within Tertiary alkali-basalt from Xinchang, Zhejiang province, china, many sulfidemelt inclusions were found by the observation of polished thin section. Electron microprobe analysis has been applied to detect the components of sulfide-melt inclusions. The result shows that the sulfide phases of inclusions are mainly pentlandite, and secondarily pyrrho- tite, The molar ratio of Ni to Fe, r_Ni,/r_Fe, of mineral phases in sulfide inclusions is related to olivine contents in host mantle xenoliths. The r_Ni/r_Ni, of sulfides from Xinchang samples has a possitive correlation to r_(Fe+Ni),/r_S. The r_(Fe+Ni),/r_S, becomes higher with the increasing of r_Ni/r_Fe In single sulfide-melt inclusions, r_Ni,/r_Fe, r_(Fe+Ni),/r, and Ni contents increase from the center to edge, reflecting a result of different cooling speed in an inclusion. A comparison between the data from Hannuoba, West Eifel of Germany and Nograd-Gomor of east Europe suggests that the composition of the inclusions is different for each area, which indicated that a regional differentiation of sulfide in mantle fluids.

关键词： mantle xenolith sulfide-melt inclusion electron microprobe analysis, Xinchang

Branched glycopolymer prodrug-derived nanoassembly combined with a STING agonist activates an immuno-supportive status to boost anti-PD-L1 antibody therapy

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第5期14卷 2194-2209页

作者： Zhilin Li qianfeng Zhang Zhiqian Li Long Ren dayi Pan Qiyong Gong Zhongwei Gu Hao Cai Kui Luo Department of Radiology Huaxi MR Research Center(HMRRC)Clinical Research Center for BreastDepartment of Breast SurgeryDepartment of Thoracic Surgery and Institute of Thoracic OncologyFrontiers Science Center for Disease-Related Molecular NetworkState Key Laboratory of BiotherapyWest China Hospital Sichuan UniversityChengdu 610041China Functional and Molecular Imaging Key Laboratory of Sichuan Province and Research Unit of PsychoradiologyChinese Academy of Medical SciencesChengdu 610041China Department of Radiology West China Xiamen Hospital of Sichuan UniversityXiamen 361021China Key Laboratory of Medicinal Chemistry for Natural Resource Ministry of EducationYunnan Key Laboratory of Research and Development for Natural ProductsSchool of PharmacyYunnan UniversityKunming 650500China

Despite the great potential of anti-PD-L1 antibodies for immunotherapy,their low response rate due to an immunosuppressive tumor microenvironment has hampered their *** address this issue,we constructed a cell membrane-coated nanosystem(mB4S)to reverse an immunosuppressive microenvironment to an immuno-supportive one for strengthening the anti-tumor *** this system,Epirubicin(EPI)as an immunogenic cell death(ICD)inducer was coupled to a branched glycopolymer via hydrazone bonds and diABZI as a stimulator of interferon genes(STING)agonist was encapsulated into *** internalization of mB4S,EPI was acidic-responsively released to induce ICD,which was characterized by an increased level of calreticulin(CRT)exposure and enhanced ATP ***,diABZI effectively activated the STING *** with mB4S in combination with an anti-PD-L1 antibody elicited potent immune responses by increasing the ratio of matured dendritic cells(DCs)and CD8+T cells,promoting cytokines secretion,up-regulating M1-like tumor-associated macrophages(TAMs)and down-regulating immunosuppressive myeloid-derived suppressor cells(MDSCs).Therefore,this nanosystem for co-delivery of an ICD inducer and a STING agonist achieved promotion of DCs maturation and CD8+T cells infiltration,creating an immuno-supportive microenvironment,thus potentiating the therapy effect of the anti-PD-L1 antibody in both 4T1 breast and CT26 colon tumor mice.

关键词： Glycopolymer Polymer prodrug Immunogenic cell death Nanoassembly Epirubicin STING pathway Immuno-supportive microenvironment Immunotherapy

Molecular Mechanism of Rice Necrotic Lesion for Optimized Yield and Disease Resistance

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rice science 2024年第3期31卷 285-299页

作者： HOU Xinyue WANG Yuping qian qian REN Deyong State Key Laboratory of Rice Biology and Breeding China National Rice Research InstituteHangzhou 310006China State Key Laboratory of Crop Gene Exploration and Utilization in Southwest china Rice Research InstituteSichuan Agricultural UniversityChengdu 611130China

How to balance rice resistance and yield is an important issue in rice *** with mutated necrotic lesion genes often have persistent broad-spectrum resistance,but this broad-spectrum resistance usually comes at the expense of ***,many necrotic lesion mutants in rice have been identified,and these genes are involved in disease resistance *** review provides a detailed introduction to the characteristics,classification,and molecular mechanisms of necrotic lesion ***,we review the molecular regulatory pathways of genes involved in rice disease ***,we summarize the relationship between resistance and yield in rice using newly developed gene editing *** discuss a rational and precise breeding strategy to better utilize molecular design technology for breeding disease-resistant and high-yield rice varieties.

关键词： rice necrotic lesion regulation mechanism high yield high resistance

The tangential k-Cauchy-Fueter type operator and Penrose type integral formula on the generalized complex Heisenberg group

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 181-190页

作者： REN Guang-zhen SHI Yun KANG qian-qian Department of Mathematics Zhejiang International Studies UniversityHangzhou 310023China Department of Mathematics Zhejiang University of Science and TechnologyHangzhou 310023China

The tangential k-Cauchy-Fueter operator and k-CF functions are counterparts of the tangential Cauchy–Riemann operator and CR functions on the Heisenberg group in the theory of several complex variables,*** this paper,we introduce a Lie group that the Heisenberg group can be imbedded into and call it generalized complex *** investigate quaternionic analysis on the generalized complex *** also give the Penrose integral formula for k-CF functions and construct the tangential k-Cauchy-Fueter complex.

关键词： the generalized complex Heisenberg group the tangential k-Cauchy-Fueter type operator Penrose-type integral formula

Effects of Na/K ratio on the phase structure and electrical properties of Na_xK_(1-x)NbO_3 lead-free piezoelectric ceramics

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2010年第2期29卷 220-225页

作者： ZHANG qian, ZHANG Boping, Li Haitao, and SHANG Pengpeng School of Materials science and Engineering, university of science and technology beijing, beijing 100083. china School of Materials science and Engineering University of Science and Technology Beijing Beijing China

Lead-free piezoelectric NaxK1-xNbO3（x = 0.3-0.8）（NKN） ceramics were fabricated by normal sintering at 1060°C for 2 *** and electrical properties of the ceramics were investigated with a special emphasis on the influence of Na *** grain size of the produced dense ceramic was decreased by increasing Na content.A discontinuous change in the space distance was found at the composition close to Na0.7K0.3NbO3 ceramic, which indicates the presence of a transitional composition between two different orthorhombic phases, which is similar to the behavior of morphotropic phase boundary（MPB） in NaxK1-xNbO3 *** MPB-like behavior contributes to the enhanced piezoelectric coefficient d33 of 122 pC/N, planar-mode electromechanical coupling coefficient kP of 28.6%, and dielectric constant εr of 703, respectively for the Na0.7K0.3NbO3 *** temperature TC and the transitional temperature TO-T from orthorhombic to tetragonal phase are observed at around 420°C and 200°C, respectively.

关键词： lead-free piezoelectric ceramics NKN sintering morphotropic phase boundary(MPB)

Prognostic value of calcium and phosphorus status in elderly heart disease patients with tricuspid regurgitation

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2024年第5期137卷 613-615页

作者： Qingrong Liu Kai Cao Ziang Li Yunqing Ye qian Zhang Hongliang Zhang Haiyan Xu Zhe Li Yongjian Wu china-DVD Collaborators Department of Cardiology Beijing Aerospace General HospitalBeijing 100076China Department of Cardiology Fuwai HospitalNational Center for Cardiovascular DiseaseChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100037China Department of beijing Institute of Ophthalmology Beijing Tongren HospitalCapital Medical UniversityBeijing 100000China 不详

To the Editor:Tricuspid regurgitation(TR)associated with valve disease is a general medical issue with growing prevalence and socioeconomic ***,especially moderate or severe TR,has been reported to be associated with an increased risk of heart failure and mortality.^([1])Studies have shown that blood calcium levels and blood phosphorus levels have a great influence on the human body,especially on the cardiovascular *** serum calcium levels were reported to be a risk factor for cardiovascular disease.^([2])A meta-analysis reported that moderate dietary calcium intake protects against cardiovascular and all-cause mortality and that calcium supplementation reduces mortality in women.^([3])

关键词： mortality regurgitation cardiovascular