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美国西语裔/拉丁美洲裔职业风险暴露与心血管病的关系

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中华高血压杂志 2019年第3期27卷 241-241页

作者：刘莉(译) 叶鹏(摘、审校) Bulka CM daviglus ml Persky VW Durazo-Arvizu RA Lash JP Elfassy T Lee DJ Ramos AR Tarraf W Argos M 不详

心血管病是美国死亡率和发病率的主要原因。尽管许多化学药品具有心脏毒性,但很少报道研究职业暴露于化学品对心血管病发展的影响。因此,该研究评估了西语裔/拉丁美洲裔工人自我报告的有机溶剂、金属和农药暴露与各种心血管病患病率之... 详细信息

心血管病是美国死亡率和发病率的主要原因。尽管许多化学药品具有心脏毒性,但很少报道研究职业暴露于化学品对心血管病发展的影响。因此,该研究评估了西语裔/拉丁美洲裔工人自我报告的有机溶剂、金属和农药暴露与各种心血管病患病率之间的关系。研究纳入参加拉丁美洲裔和西语裔社区健康研究的7404名年龄在18~74岁的个体的横断面数据,来自美国4个城市的参与者提供了问卷数据并接受临床检查,包括心电图。

关键词：心血管病心房颤动心力衰竭拉丁美洲

膳食中钠(盐)与血压的关系及其他膳食因素可能的调节作用

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中华高血压杂志 2018年第4期26卷 316-316页

作者：刘莉叶鹏 Stamler J Chan Q daviglus ml Dyer AR Van Horn L Garside DB Miura K Wu Y Ueshima H Zhao L Elliott P INTERMAP Research Group

现有资料表明,膳食钠（盐）与血压直接相关。以往大多数研究结果来自缺乏膳食数据的研究;因此,这种钠-血压关系是否受其他膳食因素调节尚不清楚。国际宏量/微量营养素和血压研究（international study on macro/micronutrients and bloo... 详细信息

现有资料表明,膳食钠（盐）与血压直接相关。以往大多数研究结果来自缺乏膳食数据的研究;因此,这种钠-血压关系是否受其他膳食因素调节尚不清楚。国际宏量/微量营养素和血压研究（international study on macro/micronutrients and blood pressure,INTERMAP）结果显示,在控制多种非膳食因素情况下,年龄40～59岁的男性和女性4680人（中国、日本、英国和美国的17个人口样本）的血压与24h尿钠排泄和尿钠／钾直接相关。

关键词：膳食因素膳食钠血压调节盐尿钠排泄微量营养素

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生与煮熟蔬菜摄入对血压的影响

中华高血压杂志 2014年第8期22卷 717-717页

作者：刘莉叶鹏 Chan Q Stamler J Brown IJ daviglus ml Van Horn L Dyer AR Oude Griep LM Miura K Ueshima H Zhao L Nicholson JK Holmes E Elliott P

已知蔬菜摄入与血压呈负相关,而这种关系是否以蔬菜煮熟为前提尚未可知。方法：纳入国际宏观与微观营养素和血压关系研究（international study of macro/micronutrients and blood pressure,INTERMAP）中40-59岁的美国人2195名,进行横... 详细信息

已知蔬菜摄入与血压呈负相关,而这种关系是否以蔬菜煮熟为前提尚未可知。方法：纳入国际宏观与微观营养素和血压关系研究（international study of macro/micronutrients and blood pressure,INTERMAP）中40-59岁的美国人2195名,进行横断面研究,探索蔬菜摄入与血压的关系。该研究采用标准化多途径24h膳食回忆方法和血压测量,应用多因素回归分析血压与生的或煮熟的蔬菜摄入、其主要成分之间的关系。结果：在多因素调整模型中,所有种类的蔬菜,不论生熟,皆与血压呈负相关。生蔬菜摄入（68g/1000kcal）与煮熟蔬菜摄入（92g/1000kcal）量每增加2个标准差,收缩压分别变化-1.

关键词：蔬菜摄入血压测量多因素回归分析营养素美国人横断面标准化标准差

Halitosis:the multidisciplinary approach

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International Journal of Oral Science 2012年第2期4卷 55-63页

作者： Curd ml Bollen Thomas Beikler Poliklinik für Zahnerhaltung Parodontologie und EndodontologieWestdeutsche KieferklinikUniversittsklinikumDüsseldorf Germany

Halitosis, bad breath or oral malodour are all synonyms for the same pathology. Halitosis has a large social and economic impact. For the majority of patients suffering from bad breath, it causes embarrassment and affects their social communication and life. Moreover, halitosis can be indicative of underlying diseases. Only a limited number of scientific publications were presented in this field until 1995. Ever since, a large amount of research is published, often with lack of evidence. In general, intraoral conditions, like insufficient dental hygiene, periodontitis or tongue coating are considered to be the most important cause （85%） for halitosis. Therefore, dentists and periodontologists are the first-line professionals to be confronted with this problem. They should be well aware of the origin, the detection and especially of the treatment of this pathology. In addition, ear-nose-throat-associated （10%） or gastrointestinal/ endocrinological （5%） disorders may contribute to the problem. In the case of halitophobia, psychiatrical or psychological problems may be present. Bad breath needs a multidisciplinary team approach： dentists, periodontologists, specialists in family medicine, ear- nose-throat surgeons, internal medicine and psychiatry need to be updated in this field, which still is surrounded by a large taboo. Multidisciplinary bad breath clinics offer the best environment to examine and treat this pathology that affects around 25% of the whole population. This article describes the origin, detection and treatment of halitosis, regarded from the different etiological origins.

关键词： halitosis microbiology periodontology

Ice Induced Low Temperature Fatigue Crack Propagation in Offshore Structural Steel A131

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China Ocean Engineering 1998年第3期13卷 275-284页

作者： Duan, ml Gao, ZJ Liu, CT China Classificat Soc Beijing 100006 Peoples R China Chinese Acad Sci Inst Mech Beijing 100080 Peoples R China

To investigate the low temperature fatigue crack propagation behavior of offshore structural steel A131 under random ice loading, three ice failure modes that are commonly present in the Bohai Gulf are simulated according to the vibration stress responses induced by real ice loading. The test data are processed by a universal software FCPUSL developed on the basis of the theory of fatigue crack propagation and statistics. The fundamental parameter controlling the fatigue crack propagation induced by random ice loading is determined to be the amplitude root mean square stress intensity factor K-arm. The test results are presented on the crack propagation diagram where the crack growth rate da/dN is described as the function of K-arm. It is evident that the ice failure modes have great influence on the fatigue crack propagation behavior of the steel in ice-induced vibration. However, some of the experimental phenomena and test results are hard to be physically explained at present. The work in this paper is an initial attempt to investigate the cause of collapse of offshore structures due to ice loading.

关键词： low temperature fatigue crack propagation offshore structure steel A131 ice load random vibration

Molecular Weight Characterization of Partially Hydrolyzed Polyacrylamide in the Complex Salts Solution

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Chinese Chemical Letters 1997年第1期8卷 73-74页

作者： Ye, ml Han, D Shi, LH ACAD SINICA INST CHEMPOLYMER PHYS LABBEIJING 100080PEOPLES R CHINA

The effects of the nature of salts, salt concentration, pH value, degree of hydrolysis as well as surfactant on molecular size of HPAM were studied. It is found that [eta] of HPAM changes with all the above variables, and the molecular weight of HPAM can be obtained through [eta] measurement at a specific salts environment in which the [eta] is independent of above factors.

关键词： Molecular Weight Characterization of Partially Hydrolyzed Polyacrylamide in the Complex Salts Solution

A New Triterpenoid Saponin from Aralia subcapitata

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Chinese Chemical Letters 2000年第10期11卷 913-914页

作者： Zou, ml Sang, SM Xia, ZH Lao, AN Chinese Acad Sci Shanghai Inst Mat Med Shanghai 200031 Peoples R China

A new oleanane-type saponin, named subcapitatoside A, has been isolated from the roots of Aralia subcapitata. On the basis of chemical and spectral evidence: the structure of subcapitatoside A has been established as:... 详细信息

关键词： Aralia subcapitat oleanane-type saponin subcapitatoside A

Impact of asialoglycoprotein receptor deficiency on the development of liver injury

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World Journal of Gastroenterology 2009年第10期15卷 1194-1200页

作者： Serene ml Lee Carol A Casey Benita L McVicker Departments of Internal Medicine and Biochemistry & Molecular Biology University of Nebraska Medical Center Omaha NE 68105 United States Liver Study Unit Department of Veterans Affairs Medical Center and Departments of Internal Medicine and Biochemistry & Molecular Biology University of Nebraska Medical Center Omaha NE 68105 United States

The asialoglycoprotein （ASGP） receptor is a wellcharacterized hepatic receptor that is recycled via the common cellular process of receptor-mediated endocytosis （RME）. The RME process plays an integral part in the proper trafficking and routing of receptors and ligands in the healthy cell. Thus, the missorting or altered transport of proteins during RME is thought to play a role in several diseases associated with hepatocyte and liver dysfunction. Previously, we examined in detail alterations that occur in hepatocellular RME and associated receptor functions as a result of one particular liver injury, alcoholic liver disease （ALD）. The studies revealed profound ethanol- mediated impairments to the ASGP receptor and the RME process, indicating the importance of this receptor and the maintenance of proper endocytic events in normal tissue. To further clarify these observations, studies were performed utilizing knockout mice （lacking a functional ASGP receptor） to which were administered several liver toxicants. In addition to alcohol, we examined the effects following administration of anti- Fas （CD95） antibody, carbon tetrachloride （CCh） and lipopolysaccharide （LPS）/galactosamine. The results of these studies demonstrated that the knockout mice sustained enhanced liver injury in response to all of the treatments, as shown by increased indices of liver damage, such as enhancement of serum enzyme levels, histopathological scores, as well as hepatocellular death. Overall, the work completed to date suggests a possible link between hepatic receptors and liver injury. In particular, adequate function and content of the ASGP receptor may provide protection against various toxinmediated liver diseases.

关键词： Asialoglycoprotein receptor Asialoglycoproteinreceptor deficient mice Receptor-mediatedendocytosis Alcohol Carbon tetrachloride Anti-Fas Lipopolysaccharide/galactosamine Toxicant-induced liverinjury

Isolation of osRACD gene encoding a small GTP-binding protein from rice

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Chinese Science Bulletin 2002年第20期47卷 1673-1679页

作者： ml Zhiyong WANG Shusheng WU Naihu Institute of Developmental Biology Chinese Academy of SciencesBeijing 100080China Academy of Life Sciences Peking UniversityBeijing 100871China

Using an improved version of mRNA differential display technology, we have obtained a differentially displayed fragment RDP-8. Homologous comparison indicated that the fragment RDP-8 has high homology with the gene encoding maize small GTP-binding protein. By screening cDNA library of the rice Nongken 58N panicle using the newly obtained fragment RDP-8 as probe, we further found the full-length cDNA of osRACD gene that encodes a rice small GTP-binding protein. As compared with maize RACD gene, the osRACD of rice shows remarkable homology in both nucleotide sequence and amino acid sequence, 88% and 97% respectively. Evidence from RT-PCR study indicates that osRACD gene is related to photoperiod fertility conversion of photoperiod sensitive genie male sterility (PSGMS) rice.

关键词： rice osRACD mRNA differential display light signal transduction.