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Context-dependent regulation of pectoralis myostatin and lipid transporters by temperature and photoperiod in dark-eyed juncos

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Current Zoology 2018年第1期64卷 23-31页

作者： Yufeng ZHANG Kathleen EYSTER david l. SWANSON Department of Biology University of South Dakota 414 East Clark Street Vermillion SD 57069 USA Basic Biomedical Sciences Sanford School of Medicine University of South Dakota Vermillion SD 57105 USA

A prominent example of seasonal phenotypic flexibility is the winter increase in thermogenic capacity (=summit metabolism, [Formula: see text]) in small birds, which is often accompanied by increases in pectoralis muscle mass and lipid catabolic capacity. Temperature or photoperiod may be drivers of the winter phenotype, but their relative impacts on muscle remodeling or lipid transport pathways are little known. We examined photoperiod and temperature effects on pectoralis muscle expression of myostatin, a muscle growth inhibitor, and its tolloid-like protein activators (Tll-1 and Tll-2), and sarcolemmal and intracellular lipid transporters in dark-eyed juncos . We acclimated winter juncos to four temperature (3 °C or 24 °C) and photoperiod [short-day (SD) = 8l:16D; long-day (lD) = 16l:8D] treatments. We found that , , , and lipid transporter mRNA expression and myostatin protein expression did not differ among treatments, but treatments interacted to influence lipid transporter protein expression. Fatty acid translocase (FAT/CD36) levels were higher for cold SD than for other treatments. Membrane-bound fatty acid binding protein (FABPpm) levels, however, were higher for the cold lD treatment than for cold SD and warm lD treatments. Cytosolic fatty acid binding protein (FABP) levels were higher on lD than on SD at 3 °C, but higher on SD than on lD at 24 °C. Cold temperature groups showed upregulation of these lipid transporters, which could contribute to elevated M compared to warm groups on the same photoperiod. However, interactions of temperature or photoperiod effects on muscle remodeling and lipid transport pathways suggest that these effects are context-dependent.

关键词：类脂化合物光周期上下文温度肌肉生长蛋白质新陈代谢分解代谢

Drag on Hydroid-Fouled Nets – An Experimental Approach

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China Ocean Engineering 2015年第3期29卷 369-389页

作者： Pl lADER david W. FREDRIKSSON Jana GUENTHER Zsolt VOlENT Nina BlOCHER david KRISTIANSEN lars GANSEl Jud DECEW SINTEF Fisheries and Aquaculture United States Naval Academy University of New Hampshire

The present study investigated the drag increase on aquaculture nets due to biofouling of the colonial hydroid Ectopleura larynx. It had two main parts： firstly the growth characteristics of E. larynx were investigated by use of field tests at a Norwegian aquaculture site; secondly the hydrodynamic drag on the fouled twines was studied in a towing tank by using fabricated models of net twines with artificial hydroid fouling. In the field tests, the growth of the hydroids was first measured after three weeks of immersion and then again after six weeks. During this interval, the density of hydroids and the thickness of the hydroid stem were almost constant（1.4 hydroids/mm and 0.29 mm, respectively）, while the average length of the hydroids increased from 6.4 to 11.2 mm. The hydroid length followed a Rayleigh distribution, while the thickness was normal（Gaussian） distributed. Replicas of twines with three different levels of hydroid growth were made（1.5 hydroids/mm twine, hydroid length 9 mm, 16 mm and 20 mm）, and the drag on these twines was measured at different towing velocities（0.1 to 1.4 m/s） and with different twine configurations. For the twine with the shortest hydroids（9 mm）, the drag was from 1.5 times（Re=4000） to 2.2 times（Re=1000） the drag on a clean twine. For the longest hydroids（21 mm）, the drag was 2 times and 3.8 times, respectively.

关键词： hydroid biofouling aquaculture net hydrodynamic drag

Prevalence and Sensitization and Intestinal Parasitic Infestation of Vernal Keratoconjunctivitis in School Children of Kinshasa

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Open Journal of Pediatrics 2023年第4期13卷 568-580页

作者： léon Muamba Nkashama david Kayembe lubeji Mireille Solange Nganga Nkanga Ophthalmology Department University Hospital of Kinshasa Kinshasa Democratic Republic of Congo Clinical Biology Department University Hospital of Kinshasa Kinshasa Democratic Republic of Congo

Background: There is no study that estimates the prevalence of vernal keratoconjunctivitis and the association between vernal keratoconjunctivitis and intestinal parasitic infestation in our setting. Purpose: This study aimed to estimate the vernal keratoconjunctivitis prevalence, describe the profile of sensitization and determine the association between vernal keratoconjunctivitis disease and intestinal parasitic infestation in school children of Kinshasa during the scholar year from 2022 to 2023. Methods: An observational, cross-sectional study was performed from September 2022 to June 2023. The children with vernal keratoconjunctivitis were recruited by using the four-stage probability sampling technique. Children attending in the school children of Kinshasa with vernal keratoconjunctivitis were enrolled in the classroom and underwent a clinical examination and skin prick test for 11 allergens and stool examination direct with microscope in the laboratory. Data were entered in Microsoft Sheets using SPSS version 20.0. The Chi-square test was used to compare the sex, age groups, home environment (grow trees and/or flowers around the yard), dampness in the house, keeping pets (cat and/or dog), number of people per household, number of people sharing a bedroom and intestinal parasitic infestation. The significant level was set to a value of p Results: A total of 28,800 students from four-stage probabilist sampling technique in school of Kinshasa were included, and 2100 students had symptoms according to the vernal keratoconjunctivitis-related symptom questionnaire. Children with vernal keratoconjunctivitis were enrolled and the mean age ± standard was 7.2 ± 3.7 years, with a prevalence of 7.2% and gender was three boys for one girl. All vernal keratoconjunctivitis children recruited in urban and rural part had 33.1% positive skin prick test (SPT) and 67.9% showed polysensitization. Children an urban part was more sensitized than rural respectively with Dermatophago

关键词： Prevalence Sensitization Intestinal Parasitic Infestation School Children Kinshasa

寒武纪早期节肢动物西德尼虫(Sidneyia)争议百年的头部结构得到澄清

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中国科学：地球科学 2023年第3期53卷 497-504页

作者：杜坤省 david l.BRUTON 杨杰张喜光玉溪师范学院古生物研究中心玉溪653100 云南大学古生物研究院昆明650500 Natural History Museum(Geology) University of OsloOslo NO-0318Norway

文章报道了产自云南寒武系第三阶小石坝生物群的小西德尼虫新种(Sidneyia minor ***.),为西德尼虫属(Sidneyia)目前所发现的最古老物种.该新种具有其他已知小西德尼虫的一些典型特征,如新月形的头甲两侧后部具眼窝(notches),柄眼从眼窝... 详细信息

文章报道了产自云南寒武系第三阶小石坝生物群的小西德尼虫新种(Sidneyia minor ***.),为西德尼虫属(Sidneyia)目前所发现的最古老物种.该新种具有其他已知小西德尼虫的一些典型特征,如新月形的头甲两侧后部具眼窝(notches),柄眼从眼窝处伸出,此外,最重要而且从未知晓的是显微-CT检测显示的头甲下3对触角后头部附肢.文章基于小西德尼虫新种和模式种的特征以及谱系分析结果,确认西德尼虫类与其他的异尾虫类(vicissicaudatans)构成姊妹群,归属物种显著分异的类肢动物(Artiopoda).

关键词：西德尼虫头部结构真节肢动物系统分类寒武系第三阶

Online traffic-aware linked VM placement in cloud data centers

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Science China(Information Sciences) 2020年第7期63卷 182-204页

作者： liwei lIN david S.l.WEI Ruhui MA Jian lI Haibing GUAN Shanghai Key laboratory of Scalable Computing and Systems Shanghai Jiao Tong University Department of Computer & Information Sciences Fordham University

In cloud computing, virtual machine(VM) placement plays a crucial role in data center(DC)management, as different ways of VM placement may require different system resources. As Cisco research reveals that virtualization of DC increases traffic within the DC and causes network bandwidth to become scarce resource, recent researches have been focusing on traffic-aware VM placement. However, previous traffic-aware VM placement schemes treat the VM placement as a static process in that they do not take into account the impact of the current placement decision on the subsequent placement. In this paper,we thus propose a novel online traffic-aware VM placement scheme. Our scheme views VM placement as a context-sensitive dynamic process in that the decision of every step of the placement is made aiming at helping the subsequent steps of placement to reduce the required network bandwidth in the long run. In our scheme, we consider not only inter-VM traffic but also the bandwidth constraint of a physical machine(PM) when making a VM placement decision. To realize our objective, we put those VMs with close end time in the same or close proximity PMs so that when the VMs are terminated, one can make enough room for the future arrivals so as to not only minimize the number of active PMs but also reduce networking costs. We conduct extensive simulations to verify the superiority of our scheme in terms of networking costs and energy consumption. Simulation results show that our scheme outperforms improved-best-fit-decreasing(IBFD) scheme, a revised best-fit version that takes inter-VM traffic into account, by 30%–40% on network cost under various scenarios. Our scheme also promises 10%–25% power savings compared with IBFD.

关键词： linked VMs traffic-aware online VM placement cloud data center energy efficient

Association between axial length and toric intraocular lens rotation according to an online toric back-calculator

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International Journal of Ophthalmology(English edition) 2022年第3期15卷 420-425页

作者： Jennifer l.Patnaik Malik Y.Kahook John P.Berdahl david R.Hardten Brandie D.Wagner leonard K.Seibold Brent A.Kramer Department of Ophthalmology University of Colorado School of MedicineAuroraColorado 80045USA Vance Thompson Vision Sioux FallsSouth Dakota 57108USA Minnesota Eye Consultants MinneapolisMinnesota 55404USA Department of Biostatistics Colorado School of Public HealthAuroraColorado 80045USA Department of Ophthalmology University of North CarolinaChapel HillNorth Carolina 27517USA

AIM: To assess the relationship between axial length(Al) and intraocular lens(IOl) rotation among eyes receiving a toric IOl and subsequently entered into an online toric back-calculator ***: Retrospective analysis of data collected online via ***, a freely available online toric back-calculator where surgeons enter pre-and postoperative information to help manage residual postoperative *** records were deemed valid with entry of Al and IOl orientation between January 2017 and March *** was determined by a difference of ≥5° between pre-operative intended IOl orientation and actual post-operative IOl *** and magnitude of rotation are presented with means and associated standard deviation(SD).linear regression models of this association are ***: Records of 6752 eyes were included in the analysis, of which 74.8% were determined to have a rotated *** magnitude of rotation increased with each millimeter(mm) increase in Al with a mean rotation of 13.3°(SD: 12.8°) for eyes with Al 20-20.9 mm and a maximum mean rotation of 30.6°(SD: 30.3°) among eyes with Al 29-29.9 *** linear modeling demonstrated a significant association(Plysis from an online database indicates that toric IOls inserted into eyes with longer Al are more likely to rotate and to rotate more degrees from the target *** findings from this study are clinically relevant for surgeons implanting toric IOls.

关键词： cataract surgery toric lens axial length rotation

Helicobacter pylori arginase mutant colonizes arginase Ⅱ knockout mice

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世界胃肠病学杂志：英文版 2011年第28期17卷 3300-3309页

作者： Songhee H Kim Melanie l langford Jean-luc Boucher Traci l Testerman david J McGee Department of Microbiology and Immunology Louisiana State University Health Sciences Center-Shreveport University of Nebraska-lincoln School of Biological SciencesLincoln laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques Université Paris Descartes

AIM: To investigate the role of host and bacterial arginases in the colonization of mice by Helicobacter pylori (***).METHODS: *** produces a very powerful urease that hydrolyzes urea to carbon dioxide and ammonium,which neutralizes *** is absolutely essential to *** pathogenesis;therefore,the urea substrate must be in ample supply for urease to work *** urea substrate is most likely provided by arginase activity,which hydrolyzes l-arginine to l-ornithine and *** work has demonstrated that *** arginase is surprisingly not required for colonization of wild-type ***,another in vivo source of the critical urea substrate must *** hypothesized that the urea source was provided by host arginase Ⅱ,since this enzyme is expressed in the stomach,and *** has previously been shown to induce the expression of murine gastric arginase Ⅱ.To test this hypothesis,wild-type and arginase (rocF) mutant *** strain SS1 were inoculated into arginase Ⅱ knockout ***: Surprisingly,both the wild-type and rocF mutant bacteria still colonized arginase Ⅱ knockout ***,feeding arginase Ⅱ knockout mice the host arginase inhibitor S-(2-boronoethyl)l-cysteine (BEC),while inhibiting > 50% of the host arginase Ⅰ?activity in several tissues,did not block the ability of the rocF mutant *** to *** contrast,BEC poorly inhibited *** arginase ***: The in vivo source for the essential urea utilized by *** urease is neither bacterial arginase nor host arginase Ⅱ;instead,either residual host arginase Ⅰ?or agmatinase is probably responsible.

关键词：幽门螺杆菌精氨酸酶基因敲除小鼠突变寄生尿素酶野生型

High–Speed electron beam curing of thick electrode for high energy density li-ion batteries

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Green Energy & Environment 2019年第4期4卷 375-381页

作者： Zhijia Du Christopher J.Janke Jianlin li david l.Wood III Energy and Transportation Science Division Oak Ridge National LaboratoryOak RidgeTN 37831USA Chemical Sciences Division Oak Ridge National LaboratoryOak RidgeTN 37831USA

Electron beam curing is demonstrated as a promising method for high speed,low cost and environmentally friendly battery electrode *** work reports transfer of this process to pilot scale equipment and evaluation of electrochemical performance in prototype 1.5 Ah pouch *** liNi0.5Mn0.3Co0.2O2(NMC532)composite electrodes with an areal loading of 25 mg cm^-2(~4 mAh cm^-2)are successfully cured at a line speed of 500 feet per minute at 275 *** to the NMC532 cathode processed via a conventional coating method,the electron beam cured electrodes show higher capacity fade in the first 100 cycles,but similar fade rate *** improvement strategies are proposed and *** work demonstrates that electron beam curing is a promising method for manufacturing thick battery electrodes at high speeds and low capital/operation cost.

关键词： Electron beam curing li-ion batteries Thick electrode

The demands of the extra-time period of soccer:A systematic review

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Journal of Sport and Health Science 2022年第3期11卷 403-414页

作者： Adam Field Robert Joseph Naughton Matthew Haines Steve lui liam david Corr Mark Russell Richard Michael Page liam david Harper School of Human and Health Sciences University of HuddersfieldHuddersfieldHD13DHUK School of Social and Health Sciences Leeds Trinity UniversityBrownberrie LaneHorsforthLeedsLS185HDUK Department of Sport&Physical Activity Edge Hill UniversitySt.Helens RoadOrmskirkLancashireL394QPUK

Background:Soccer match-play is typically contested over 90 min;however,in some cup and tournament scenarios,when matches are tied,they proceed to an additional 30 min,which is termed "extra-time^(ET).This systematic review sought to appraise the literature available on 120-min of soccer-specific exercise,with a view to identifying practical recommendations and future research ***:The review was conducted according to the PRISMA *** researchers performed a systematic search of PubMed,CINAHl,and PsycINFO in May 2019,with the following keywords entered in various combinations:"soccer","football","extra-time","extra time","extratime","120 minutes","120 min","additional 30 minutes",and "additional 30 min".Results:The search yielded an initial 73 *** the screening process,11 articles were accepted for *** were subsequently organized into the following 5 categories:movement demands of ET,performance responses to ET,physiological and neuromuscular response during ET,nutritional interventions,and recovery and *** results highlighted that during competitive match-play,players cover5%-12% less distance relative to match duration(i.e.,meters per minute) during ET compared to the preceding 90 *** in technical performance(i.e.,shot speed,number of passes and dribbles) were also observed during ***,carbohydrate provision may attenuate and improve dribbling performance during ***,objective and subjective measures of recovery may be further compromised following ET when compared to 90 ***:Additional investigations are warranted to further substantiate these findings and identify interventions to improve performance during ET.

关键词： Movement demands Neuromuscular fatigue Nutritional intervention Performance Physiology