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Bright spots for inland fish and fisheries to guide future hydropower development

Water Biology and Security 2022年第1期1卷 81-99页

作者： William M.Twardek Ian G.Cowx Nicolas W.R.Lapointe Craig Paukert T.Douglas Beard Elena M.Bennett david browne Andrew K.Carlson Keith D.Clarke Zeb Hogan Kai Lorenzen Abigail J.Lynch Peter B.McIntyre Paulo Pompeu Mark Rogers Alexis Sakas William W.Taylor Taylor D.Ward Zeenatul Basher Steven J.Cooke Fish Ecology and Conservation Physiology Laboratory Department of Biology and Institute for Environmental StudiesCarleton University1125 Colonel By DrOttawaON K1S 5B6Canada Fisheries Institute at the University of Hull Cottingham RdHullHU67RXUnited Kingdom Canadian Wildlife Federation 350 Michael Cowpland DrKanataONK2M 2W1Canada U.S.Geological Survey Missouri Cooperative Fish and Wildlife Research UnitUniversity of MissouriColumbiaMO65211United States U.S.Geological Survey National Climate Adaptation Science Center12201 Sunrise Valley DriveMS-516RestonVA20192United States McGill School of Environment McGill University845 Sherbrooke St WMontrealQuebec H3A 0G4Canada Princeton Environmental Institute and Department of Ecology and Evolutionary Biology Princeton UniversityM30 Guyot HallPrincetonNJ08544United States Ecological Sciences Section Science Branch Fisheries and Oceans CanadaCanadaPO Box/CP 5667St.John'sNewfoundland and LabradorA1C 5X1Canada University of Nevada Reno.4505 S Maryland PkwyLas VegasNV89154United States Fisheries and Aquatic Sciences School of Forest Resources and ConservationUniversity of Florida7922 NW 71st StreetGainesvilleFL32653United States Department of Natural Resources Cornell UniversityIthacaNY14853United States Departamento de Biologia Universidade Federal de LavrasAquenta SolLavrasState of Minas Gerais37200-900Brazil U.S.Geological Survey Tennessee Cooperative Fishery Research UnitTennessee tech UniversityCookevilleTN38505United States The Nature Conservancy 6375 Riverside DriveSuite 100DublinOH43017United States Michigan State University Department of Fisheries and WildlifeEast LansingMI48823United States

Hydropower production is one of the greatest threats to fluvial ecosystems and freshwater *** that we have entered the Anthropocene,there is an opportunity to reflect on what might constitute a‘sustainable’Anthropocene in the context of hydropower and riverine fish *** elements of existing practices that promote favorable social-ecological outcomes(i.e.,‘bright spots’)is timely given that there are plans to expand hydropower capacity in previously undammed rivers,intensify dam development in some of the world's largest river systems,and re-license existing *** approach this from a pragmatic perspective:for the foreseeable future,hydropower will likely remain an important source of renewable *** offer support for moving toward a more‘sustainable’Anthropocene,we provide syntheses of best practices during the siting,design,construction,operation,and compensation phases of hydropower development to minimize impacts on inland *** each phase,we offer positive examples(or what might be considered‘bright spots’)pertaining to some of the approaches described within our syntheses,acknowledging that these projects may not be viewed as without ecological and(or)societal detriment by all *** findings underscore the importance of protecting critical habitat and free-flowing river reaches through careful site selection and basinscale planning,infrastructure designs that minimize reservoir effects and facilitate safe passage of fish,construction of hydropower plants using best practices that minimize long-term damage,operating guidelines that mimic natural flow conditions,and compensation that is lasting,effective,inclusive,and locally *** from these‘bright spots’may require engagement of diverse stakeholders,professionals,and governments at scales that extend well beyond a given site,river,or even ***,environmental planning that integrates hydropower development into broader discussions

关键词： Migration Dams Salmon Hydroelectric Flow Socioecological Fish passage Barriers Ecosystems

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Making bridges between preclinical and clinical insights into age-related cognitive decline

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Neural Regeneration Research 2025年第8期20卷 2321-2322页

作者： david VC Brito Clévio Nóbrega Algarve Biomedical Center-Research Institute(ABC-RI) Campus GambelasFaroPortugal Algarve Biomedical Center-(ABC) Campus GambelasFaroPortugal Faculty of Medicine and Biomedical Sciences(FMCB) University of AlgarveGambelas CampusFaroPortugal

With people living longer,the societal impact of age-related cognitive decline is becoming more pronounced(Crimmins,2015).Thus,it is increasingly important to comprehend the cognitive shifts linked to aging-whether th... 详细信息

关键词： bridges becoming insight

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Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia S.Rex david J.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the Massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included PubMed,the National Science Foundation(NSF),the NEI,the Blue Ridge Institute for Medical Research and data from the major professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

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Pathophysiology of pulmonary complications of acute pancreatitis

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World Journal of Gastroenterology 2006年第44期12卷 7087-7096页

作者： George W browne CS Pitchumoni Saint Peter’s University Hospital Robert Wood Johnson Medical School New Brunswick NJ 08903 United States Robert Wood Johnson School of Medicine Saint Peter’s University Hospital New Brunswick NJ 08903 United States

Acute pancreatitis in its severe form is complicated by multiple organ system dysfunction, most importantly by pulmonary complications which include hypoxia, acute respiratory distress syndrome, atelectasis, and pleural effusion. The pathogenesis of some of the above complications is attributed to the production of noxious cytokines. Clinically significant is the early onset of pleural effusion, which heralds a poor outcome of acute pancreatitis. The role of circulating trypsin, phospholipase A2, platelet activating factor, release of free fatty acids, chemoattractants such as tumor necrsosis factor （TNF）- alpha, interleukin （IL）-1, IL-6, IL-8, fMet-leu-phe （a bacterial wall product）, nitric oxide, substance P, and macrophage inhlbitor factor is currently studied. The hope is that future management of acute pancreatitis with a better understanding of the pathogenesis of lung injury will be directed against the production of noxious cytokines.

关键词： Acute pancreatitis Cytokines Acute respiratory distress syndrome Complications of pancreatitis Pleural effusion Interleukins

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Region-specific microRNA signatures in the human epididymis

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Asian Journal of Andrology 2018年第6期20卷 539-544页

作者： James A browne Shih-Hsing Leir Scott E Eggener Ann Harris Department of Genetics and Genome Sciences Case Western Reserve UniversityClevelandOH 44106USA Human Molecular Genetics Program Lurie Children＇s Research CenterChicagoIL 60614USA Department of Pediatrics Northwestern University Feinberg School of MedicineChicagoIL 60611USA Section of Urology University of Chicago Medical CenterChicagoIL 60611USA.

The epithelium of the human epididymis maintains an appropriate luminal environment for sperm maturation that is essential for male fertility. Regional expression of small noncoding RNAs such as microRNAs contributes to segment-specific gene expression and differentiated functions. MicroRNA profiles were reported in human epididymal tissues but not specifically in the epithelial cells derived from those regions. Here, we reveal miRNA signatures of primary cultures of caput, corpus, and cauda epididymis epithelial cells and of the tissues from which they were derived. We identify 324 epithelial cell-derived microRNAs and 259 tissue-derived microRNAs in the epididymis, some of which displayed regionalized expression patterns in cells and/or tissues. Caput cell-enriched miRNAs included miR-573 and miR-155. Cauda cell-enriched miRNAs included miR-1204 and miR-770. Next, we determined the gene ontology pathways associated with in silico predicted target genes of the differentially expressed miRNAs. The effect of androgen receptor stimulation on miRNA expression was also investigated. These data show novel epithelial cell-derived miRNAs that may regulate the expression of important gene networks that are responsible for the regionalized gene expression and function of the epididymis.

关键词： caput cauda corpus human epididymis microRNA

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Journey Through the Groan Zone with Academics and Practitioners: Bridging Conflict and Difference to Strengthen Disaster Risk Reduction and Recovery Work

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International Journal of Disaster Risk Science 2018年第3期9卷 421-428页

作者： Katherine E.browne Caela O'Connell Laura Meitzner Yoder Department of Anthropology Colorado State University Department of Anthropology – Disasters Displacement and Human Rights Program University of Tennessee Program in Human Needs and Global Resources Wheaton College

Academic-practitioner divides in disaster management and research can be persistent and pernicious,bearing consequences for disaster survivors and future affected populations. The gap between disaster professionals and academic researchers is often treated as an unavoidable structural problem or a neutral accident of professional silos and circumstance. We suggest that these gaps are not neutral, and that they can and must be overcome. With hundreds of millions of people affected by disaster each year and recovery costs skyrocketing, there is urgency in connecting researcher and practitioner knowledges to avoid expensive mistakes and most importantly, to decrease human suffering. Yet the difficulties that US academic anthropologists and practitioners experienced in their efforts to collaborate became evident in a cross-sector National Science Foundation(NSF)-funded workshop on the relevance of culture in disaster work. We suggest and illustrate how more systematic cross-field communication can be operationalized through engaging in an ongoing and relational process of bridging. Such a process can offer long-term benefits to the people and institutions involved,dramatically enhance the science of disaster management,and help reduce the social and material costs of disaster impacts.

关键词： Academic and practitioner divide Applied research Cross-sector communication Culture and disaster Disaster anthropology Disaster management

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Transformation of leather waste into microwave-activated and N-doped carbon for Li-S batteries

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新型炭材料(中英文) 2025年

作者： Carolina Pano-Azucena Roberto Rosas-Rangel Miguel Olvera-Sosa david Salvador González-González Rene Rangel-Mendez Luis Felipe Chazaro-Ruiz Miguel Avalos-Borja Javier Antonio Arcibar-Orozco CIATEC.Center for Applied Innovation in Competitive Technologies Tecnologico de Monterrey School of Engineering and Sciences Instituto Potosino de Investigación Científica y Tecnológica Universidad Autónoma de Coahuila Facultad de SistemasCiudad Universitaria

The use of carbon from waste biomass has the potential to buffer the drawbacks of Li-S batteries and improve their overall performance. Chrome-Tanned-LeatherShavings(CTLS) are undesirable wastes, highly available for transformation into porous carbon. Microwave activation is an efficient state-of-the-art procedure to obtain unique porous structures and nitrogen incorporation can improve the performance of porous carbons. This study proposes the transformation of CTLS into a microwave activated porous carbon, and then was modified to introduce nitrogen. A microporous activated carbon with a specific surface area of 556 m2g-1 with honeycomb-like structure was obtained. Both urea thermal decomposition and ethanolamine impregnation improves the nitrogen and amine presence of surface groups. However,the results indicated that only urea treatment was effective in improving the initial capacity of the cell(1363 mAhg-1), which is probably linked with the sorption of long-chain polysulfides. This investigation confirms that it is possible to obtain carbon materials from CTLS, for use as sulfur-host cathodes in Li-S batteries, and improve their performance with urea thermal decomposition. Furthermore, a Radial basis function neural network was fitted to provide statistical support to the experimental results. The trained model corroborated the importance of nitrogen content of the carbons in the discharge capacity of the cells.

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Reconstruction options for acetabular revision

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World Journal of Orthopedics 2012年第7期3卷 95-100页

作者： Erica D Taylor James A browne Department of Orthopaedic Surgery University of VirginiaCharlottesvilleVA 22908United States

This article summarizes reconstruction options available for acetabular revision following total hip arthroplasty. A thoughtful methodology to the evaluation and treatment of patients with implant failure after joint replacement is essential to guarantee accurate diagnoses, appropriate triage to reconstruction options, and optimal clinical outcomes. In the majority of patients who undergo acetabular revision, factors such as bone loss and pelvic discontinuity provide a challenge in the selection and implementation of the proper reconstruction option. With advanced evaluation algorithms, imaging techniques, and implant designs, techniques have evolved to rebuild the compromised acetabulum at the time of revision surgery. However, clinical outcomes data for these techniques continue to lag behind the exponential increase in revision hip arthroplasty cases predicted to occur over the next several years. We encourage those involved in the treatment of patients undergoing hip replacement surgery to participate in well-designed clinical studies to enhance evidence-based knowledge regarding revision acetabular reconstruction options.

关键词： Hip Arthoplasty Revision Acetabulum Tantalum

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Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina Hromada Patrick Heimel Markus Kerbl LászlóGál Sylvia Nürnberger Barbara Schaedl James Ferguson Nicole Swiadek Xavier Monforte Johannes C.Heinzel Antal Nógrádi Andreas H.Teuschl-Woller david Hercher Department Life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria Ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of Hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tNGCs). However, the use of tNGCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNGC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tNGCs and compared the various features of these improved silk^(+) tNGCs with the tubes without holes(silk^(–) tNGCs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tNGCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNGCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tNGCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNGCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

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Complement-dependent neuroinflammation in spinal cord injury:from pathology to therapeutic implications

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Neural Regeneration Research 2025年第5期20卷 1324-1335页

作者： Hassan Saad Bachar El Baba Ali Tfaily Firas Kobeissy Juanmarco Gutierrez Gonzalez Daniel Refai Gerald R.Rodts Christian Mustroph david Gimbel Jonathan Grossberg Daniel L.Barrow Matthew F.Gary Ali M.Alawieh Department of Neurosurgery Emory University School of MedicineAtlantaGAUSA Department of Neurology Yale UniversityNew HavenCTUSA Center for Neurotrauma Multiomics&Biomarkers(CNMB)Morehouse School of MedicineAtlantaGAUSA

Spinal cord injury remains a major cause of disability in young adults,and beyond acute decompression and rehabilitation,there are no pharmacological treatments to limit the progression of injury and optimize recovery in this *** the thorough investigation of the complement system in triggering and propagating cerebral neuroinflammation,a similar role for complement in spinal neuroinflammation is a focus of ongoing *** this work,we survey the current literature investigating the role of complement in spinal cord injury including the sources of complement proteins,triggers of complement activation,and role of effector functions in the *** study relevant data demonstrating the different triggers of complement activation after spinal cord injury including direct binding to cellular debris,and or activation via antibody binding to damage-associated molecular *** effector functions of complement have been implicated in spinal cord injury,and we critically evaluate recent studies on the dual role of complement anaphylatoxins in spinal cord injury while emphasizing the lack of pathophysiological understanding of the role of opsonins in spinal cord *** this pathophysiological review,we systematically review the different translational approaches used in preclinical models of spinal cord injury and discuss the challenges for future translation into human *** review emphasizes the need for future studies to dissect the roles of different complement pathways in the pathology of spinal cord injury,to evaluate the phases of involvement of opsonins and anaphylatoxins,and to study the role of complement in white matter degeneration and regeneration using translational strategies to supplement genetic models.

关键词： complement neuroinflammation neuroplasticity regeneration spinal cord injury targeted therapy

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