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Particuology 2016年第4期14卷 141-142页

作者： david y.h. pui Junji Cao University of Minnesota MN 55455 USA Institute of Earth Environment Chinese Academy of Sciences Xi'an China

The First UMN-CAS Bilateral Seminar was successfully.h.ld in Xi＇an, China, May 27-28,2014. A summary of the 1 st Bilateral Seminar was published in Particuology 16 （2014）, 227-229. The Second UMN-CAS Bilateral Semi... 详细信息

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PM_(2.5) in China:Measurements,sources,visibility and health effects,and mitigation

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Particuology 2014年第2期12卷 1-26页

作者： david y.h.pui Sheng-Chieh Chen Zhili Zuo Department of Mechanical Engineering College of Science and EngineeringUniversity of Minnesota

Concern over the health effects of fine particles in the ambient environment led the U.S. Environmental Protection Agency to develop the first standard for PM2.5 （particulate matter less than 2.5 μm） in 1997. The Particle Technology Laboratory at the University of Minnesota has helped to establish the PM2.5 standard by developing many instruments and samplers to perform atmospheric measurements. In this paper, we review various aspects of PM2.5, including its measurement, source apportionment, visibility and health effects, and mitigation. We focus on PM2.s studies in China and where appropriate, compare them with those obtained in the U.S. Based on accurate PM2.5 sampling, chemical analysis, and source apportionment models, the major PM2.5 sources in China have been identified to be coal combustion, motor vehicle emissions, and industrial sources. Atmospheric visibility.h.s been found to correlate well with PM2.s concentration. Sulfate, ammonium, and nitrate carried by PM2.s, commonly found in coal burning and vehicle emissions, are the dominant contributors to regional haze in China. Short-term exposure to PM2.s is strongly associated with the increased risk of morbidity and mortality from cardiovascular and respiratory diseases in China. The strategy for PMzs mitigation must be based on reducing the pollutants from the two primary sources of coal-fired power plants and vehicle emissions. Although conventional Particulate Emission Control Devices （PECD） such as electrostatic precipitators in Chinese coal-fired power plants are generally effective for large particles, most of them may not have high collection efficiency of PM2.5. Baghouse filtration is gradually incorporated into the PECD to increase the PM2.5 collection efficiency. By adopting stringent vehicle emissions standard such as Euro 5 and 6, the emissions from vehicles can be gradually reduced over the years. An integrative approach, from collaboration among academia, government, and industries, can effe

关键词： PM2.5 in ChinaAtmospheric particle size distributionPM2.5 samplingChemical composition of PM2.sSource apportionment modelsPM2.5 health impactPM2.s mitigationCoal-fired power plantParticle emission control devices (PECD)Baghouse filtrationIntegrative approach

Great wall of solar panels to mitigate yellow dust storm

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Particuology 2014年第2期12卷 146-149页

作者： david y.h.pui Junji Cao Zhisheng An Jing Wang University of Minnesota Department of Mechanical EngineeringMinneapolisMN 55455USA Institute of Earth Environment Chinese Academy of Sciences ETh Zurich Institute of Environmental Engineering8093 ZurichSwitzerland EMPA Analytical Chemistry8600 Dubendorf Switzerland

Mitigation of the large scale yellow dust storm is a serious problem facing China. We propose the approach of building windbreak walls equipped with solar panels in the proximity of dust origins. The solar panels generate electricity in the sunny days; the walls break the wind and remove airborne dusts based on the impactor principle during wind storms. Preliminary calculation indicates the walls may be able to remove the major fraction of the airborne dusts and the generated electricity could be significant. More detailed studies are needed to prove the feasibility of the approach.

关键词： Solar panels Dust storm Mitigation Windbreak Sustainable development

Integrative filtration research and sustainable nanotechnology

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Particuology 2013年第1期11卷 5-13页

作者： Jing Wang Drew Thompson david y.h.pui Institute of Environmental Engineering ETH Zurich 8093Switzerland Analytical Chemistry Empa8600 DubendorfSwitzerland Particle Technology Laboratory University of Minnesota55455USA

With the wide applications of nanomaterials in an array of industries, more concerns are being raised about the occupational health and safety of nanoparticles in the workplace, and implications ofnanotech- nology on the environment and living systems. Studies on environmental, health and safety （EhS） issues of nanomaterials play a significant role in public acceptance, and eventual sustainability, of nanotechnol- ogy. We present research results on three aspects of the EhS studies： characterization and measurement of nanoparticles, nanoparticle emission and exposure at workplaces, and control and abatement of nanoparticle release using filtration technology. Measurement of nanoparticle agglomerates using a newly developed instrument, the Universal Nanoparticle Analyzer, is discussed. Nanoparticle emission and exposure measurement results for carbon nanotubes in the manufacture of nanocomposites and for silicon nanoparticles in their production at a pilot scale facility are presented. Filtration of nanoparticles and nanoparticle agglomerates are also studied.

关键词： Agglomerate Sustainability Exposure Filtration Nano-EhS Nanoparticle

Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina hromada Patrick heimel Markus Kerbl LászlóGál Sylvia Nürnberger Barbara Schaedl James Ferguson Nicole Swiadek Xavier Monforte Johannes C.heinzel Antal Nógrádi Andreas h.Teuschl-Woller david hercher Department Life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria Ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tNGCs). however, the use of tNGCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNGC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tNGCs and compared the various features of these improved silk^(+) tNGCs with the tubes without holes(silk^(–) tNGCs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tNGCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly.h.gher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNGCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tNGCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNGCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

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基于载锰沸石分子筛的臭氧催化分解特性

工程科学学报 2025年第1期47卷 170-178页

作者：陈浩玥郭卓男刘应书杨雄裴有康李子宜北京科技大学能源与环境工程学院北京100083 香港中文大学(深圳)理工学院深圳518172 明尼苏达大学机械工程系明尼阿波利斯55455

臭氧作为重点防控的室内气态污染物广泛存在于人类生产、生活中,亟待开发高效的臭氧分解转化器从源头进行净化,催化剂是其核心关键.本文基于金属离子改性沸石分子筛进行臭氧催化性能研究,基于不同沸石拓扑结构、阳离子种类、改性手段及... 详细信息

臭氧作为重点防控的室内气态污染物广泛存在于人类生产、生活中,亟待开发高效的臭氧分解转化器从源头进行净化,催化剂是其核心关键.本文基于金属离子改性沸石分子筛进行臭氧催化性能研究,基于不同沸石拓扑结构、阳离子种类、改性手段及干燥方法,优选得到了采用等体积浸渍法和微波干燥法组合制备的载锰USy沸石Mn-USy-DT/WB,相较商用臭氧分解催化剂具有可逆再生的优势.通过系列表征,提出了可能的长效稳定催化臭氧的机制:单位时间内臭氧分子在沸石上的吸附与催化分解的相互协调,决定了沸石对臭氧的稳态催化分解,呈现宏观所得的脱除效率随时间变化曲线.通过XPS表征分析优选沸石升温可逆再生的潜在原因,再生后Mn-USy-DT/WB的平均化合态(Average oxidation state,AOS)由2.95降至2.81,经过加热处理后部分吸附在活性位点的中间氧物种脱附,氧空位释放,因此催化活性恢复.将优选沸石涂敷制得整体式蜂窝沸石催化剂,在实际应用条件(170℃、50000 h-1空速)下可维持99%臭氧分解效率1000 h以上.本工作为长效低阻臭氧分解催化剂的开发提供了新思路.

关键词：臭氧催化剂沸石分子筛整体式蜂窝催化剂再生

1st UMN-CAS Bilateral Seminar on PM_(2.5) science,health effects and control technology Xi'an,China,May 27-28,2014

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Particuology 2014年第5期12卷 227-229页

作者： Cao, Junji pui, david y. h. Kuehn, Thomas T. Tie, Xuexi Ramachandran, G. Zhu, Tong Wang, Jing Tao, Wenquan Chinese Acad Sci Inst Earth Environm Xian Peoples R China Univ Minnesota Minneapolis MN 55455 USA Peking Univ Beijing 100871 Peoples R China ETh CH-8093 Zurich Switzerland Empa CH-8600 Dubendorf Switzerland Xi An Jiao Tong Univ Xian 710049 Peoples R China

The First UMN-CAS Bilateral Seminar was successfully con- cluded with all the goals met. The meeting in Xi＇an was informative, stimulating and enjoyable, thanks to the local host, Prof. Junji Cao, and his capable staff. The Bilateral Seminar was organized by Prof. david y.h. pui of the University of Minnesota and Prof. Junji Cao of the Institute of Earth Environment, Chinese Academy of Sci- ences. It was attended by approximately 100 delegates from the University of Minnesota （UMN）, the Center for Filtration Research （CFR）, the Chinese Academy of Sciences （CAS） and other famous Chinese universities. We are grateful for the opening remarks given by UMN President Eric hai Li on behalf of President Kaler and CAS Vice President Jing- Chunli Bai.

关键词： PM UMN-CAS Bilateral Seminar on PM science,health effects and control technology Xi’an,China,May 27-28,2014 CAS

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Particuology 2014年第2期12卷 150-150页

作者： david y.h.pui Junji Cao Zhisheng An Jing Wang

We are grateful for the experts＇ comments on our manuscript. We fully understand the experts＇ concerns on the feasibility of the proposed idea of building windbreak walls equipped with solar panels to mitigate the yellow dust storm. As stated in the manuscript, we have not considered many important factors, such as the limits posed by solar panels, operability of solar panels under harsh conditions, the local weather and geomorphological conditions, electricity storage and transportation, financial aspects, etc. however, the manuscript is intended to present a Big Idea to stimulate more interesting ideas to solve Big Problems.

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TIMP-1 Production in human Retinal Pigment Epithelial Cells after Laser Exposure

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Eye Science 2005年第1期21卷 31-37页

作者： Alvin K.h.Kwok Timothy y.y.Lai hin-Fai yam Chi-pui Pang Department of Ophthalmology & Visual Sciences Department of Ophthalmology & Visual SciencesDepartment of Ophthalmology & Visual SciencesDepartment of Ophthalmology & Visual Sciences The Chinese University of Hong KongHong Kong SAR Department of OphthalmologyHong Kong Sanatorium and HospitalHong Kong SARThe Chinese University of Hong KongHong Kong SARThe Chinese University of Hong KongHong Kong SARThe Chinese University of Hong KongHong Kong SAR

Purpose: To investigate changes in the production of tissue inhibitor of metalloproteinase type 1 (TIMP-1) by.h.man retinal pigment epithelial (RPE) cells following argon laser ***: human cultured ARPE19 cells were exposed to argon green laser at four different energy levels ranging from 60mW to 360mW. After laser exposure, the culture media were sampled at 0, 24, 72 and 144 hours for TIMP-1 concentration produced by the RPE cells. The levels of TIMP-1 in the cells treated with different laser energy levels were compared with a control group not exposed to laser *** for proliferating cell nuclear antigen (PCNA) was performed to detect any adverse effects on the RPE cells caused by laser ***: Immediately after laser exposure, the concentration of TIMP- 1 was not detectable. At 24 hours after laser exposure, the concentration of TIMP-1 increased significantly in RPE cells treated with 120mW and 240mW at 24 hours (P=0.006 and P=0.001respectively) compared with control cells. At 72 hours after treatment, RPE cells treated at 120mW, 240mW and 360mW demonstrated significantly increase in TIMP-1production compared with control (P=0.003, P ＜ 0.001 and P ＜ 0.001, respectively).No significant reduction in cell viability was observed following laser application as detected by PCNA ***: Our results demonstrated that early TIMP-1 production by RPE cells in cell cultures was enhanced following laser exposure.

关键词： TIMP-1 视网膜上皮细胞激光损伤免疫细胞学视色素

history of helicobacter pylori,duodenal ulcer,gastric ulcer and gastric cancer

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World Journal of Gastroenterology 2014年第18期20卷 5191-5204页

作者： david y Graham Michael E DeBakey VA Medical Center Baylor College of MedicineHoustonTX 77030United States

helicobacter pylori (h. pylori) infection underlies gastric ulcer disease, gastric cancer and duodenal ulcer disease. The disease expression reflects the pattern and extent of gastritis/gastric atrophy (i.e., duodenal ulcer with non-atrophic and gastric ulcer and gastric cancer with atrophic gastritis). Gastric and duodenal ulcers and gastric cancer have been known for thousands of years. Ulcers are generally non-fatal and until the 20th century were difficult to diagnose. however, the presence and pattern of gastritis in past civilizations can be deduced based on the diseases present. It has been suggested that gastric ulcer and duodenal ulcer both arose or became more frequent in Europe in the 19th century. here, we show that gastric cancer and gastric ulcer were present throughout the 17th to 19th centuries consistent with atrophic gastritis being the predominant pattern, as it proved to be when it could be examined directly in the late 19th century. The environment before the 20th century favored acquisition of h. pylori infection and atrophic gastritis (e.g., poor sanitation and standards of living, seasonal diets poor in fresh fruits and vegetables, especially in winter, vitamin deficiencies, and frequent febrile infections in childhood). The latter part of the 19th century saw improvements in standards of living, sanitation, and diets with a corresponding decrease in rate of development of atrophic gastritis allowing duodenal ulcers to become more prominent. In the early 20th century physician’s believed they could diagnose ulcers clinically and that the diagnosis required hospitalization for “surgical disease” or for “Sippy” diets. We show that while h. pylori remained common and virulent in Europe and the United States, environmental changes resulted in changes of the pattern of gastritis producing a change in the manifestations of

关键词： helicobacter pylori Duodenal ulcer Gastric ulcer Gastric cancer Medical history Ulcer surgery Epidemiology Gastritis Atrophic gastritis Antiquity