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Evaluation of Ocimum basilicum *** Different Concentrations of K^(+)as an Inhibitor of Pathogenic Bacterial Strains

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Phyton-International Journal of Experimental Botany 2021年第2期90卷 533-541页

作者： Mercedes Georgina Ramírez-Aragón Victoria Jared Borroel-garcía Ramón Valenzuela-Soto Ricardo david Valdez-Cepeda Francisco Javier Wong-Corral Joséluis garcía-Hernández Universidad Politécnica de Gómez Palacio Gómez Palacio35120México Universidad Autónoma Chapingo Centro Regional Universitario Centro-NorteZacatecasZac.Universidad Autónoma de ZacatecasFacultad de MatemáticasZacatecas98053México Departamento de Investigación y Posgrado en Alimentos Universidad de SonoraHermosillo83000México Facultad de Agricultura y Zootecnia Universidad Juárez del Estado de DurangoGómez Palacio34000México

The extraction of bioactive compounds has become one of the most interesting areas of modern *** therapeutic reasons,it´s important to obtain antimicrobial agents from natural *** objective of the present study was to determine the inhibitory effect of ethanolic extract of basil(Ocimum basilicum *** Rubin)subjected to different concentrations of potassium(K^(+))on the activity of three bacterial strains that are pathogens in *** was evaluated by inhibition surface and these results were compared to two antibiotics:Gentamicin(GE)and Ciprofloxacin(CPF)for their efficacy against each bacterial *** variables presented significant difference(p≤0.05).According to the results,basil extract evaluated showed positive antibacterial activity against the three strains of Pseudomonas aeruginosa,listeria monocytogenes and Staphylococcus aureus on Mueller Hinton *** was observed highest inhibition areas of different diameters(15.3 mm,21.3 mm and 21.6 mm respectively)when the extract used was obtained from the plants with the highest concentration of potassium(13 mmol l-1).These values were even superior to the highest values showed on the treatments with the antibiotic gentamicin.

关键词： Basil inhibition potassium secondary metabolites antibiotics

Discharge-Stage Relationship on Urban Streams Evaluated at USGS Gauging Stations,***,Missouri

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Journal of Earth Science 2020年第6期31卷 1133-1141页

作者： Robert E.Criss david l.Nelson Department of Earth and Planetary Sciences Washington UniversitySt.Louis MO 63130USA Columbia Cir Pasadena CA 91105USA

Extensive USGS data tables and detailed,1 m2 li DAR surveys are used to determine the optimal power n that relates discharge(Q)to stage(h*)above channel bottom(ho)at 39 gauging stations on small streams in the ***,Missouri area,all of which have catchments of 0.6 to 220 *** different methodologies are employed to determine both n and ho:(1)optimizing linearity in a plot of Q1/n *** stage(hl)using USGS field measurements at each site;(2)optimizing linearity in a plot of Q1/n *** using USGS rating tables at each site;(3)a mathematical inverse method applied to the same USGS rating tables;(4)use of li DAR data on channel geometry to determine the power dependences of channel area A and hydraulic radius H on h*,combined with the Manning and rational equations to predict *** these methods,only methods 2 and 3 compare favorably,and these values compare poorly with Method 1 based on field data,and with method 4 based on theoretical and empirical *** Method 4 is predictive,it provides a useful alternative to methods 1–3 that are based on USGS field measurements,which are heavily weighted toward low *** conclude that the apparent values of n in the USGS rating tables are systematically too low for small streams.

关键词： stream gauging li DAR topography urban flooding discharge hydrology

Host-parasite interactions in perpetual darkness:Macroparasite diversity in the cavefish Astyanax mexicanus

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Zoological Research 2023年第4期44卷 782-792页

作者： Ana Santacruz david Hernández-Mena Ramses Miranda-Gamboa Gerardo Pérez-Ponce De león Claudia Patricia Ornelas-garcía Departamento de Zoología Instituto de BiologíaUniversidad Nacional Autónoma de MéxicoMéxico City CP 04510México Departamento de Sistemas y Procesos Naturales Escuela Nacional de Estudios Superiores Unidad MéridaUcúYucatán CP 97357México Instituto de Energías Renovables Universidad Nacional Autónoma de MéxicoTemixcoMorelos CP 62580México Colección Nacional de Peces Departamento de ZoologíaInstituto de BiologíaUniversidad Nacional Autónoma de MéxicoMéxico City CP 04510México Stowers Institute for Medical Research Kansas CityMO 64110USA

Astyanax mexicanus has repeatedly colonized cave environments,displaying evolutionary parallelisms in many troglobitic *** being a model system for the study of adaptation to life in perpetual darkness,the parasites that infect cavefish are practically *** this study,we investigated the macroparasite communities in 18 cavefish populations from independent lineages and compared them with the parasite diversity found in their sister surface fish populations,with the aim of better understanding the role that parasites play in the colonization of new *** the cavefish populations,we identified 13 parasite taxa,including a subset of 10 of the 27 parasite taxa known for the surface *** infecting the cavefish belong to five taxonomic groups,including trematodes,monogeneans,nematodes,copepods,and *** are the most dominant group,found in 14 *** macroparasites include species with direct life cycles and trophic transmission,including invasive ***,paired comparisons indicate higher parasite richness in the cavefish than in the surface *** variation in parasite composition across the caves suggests historical and geographical contingencies in the host-parasite colonization process and potential evolution of local *** base-line data on parasite diversity in cavefish populations of *** provides a foundation to explore the role of divergent parasite infections under contrasting ecological pressures(cave *** environments)in the evolution of cave adaptive traits.

关键词： Adaptation Metazoan parasites Niche change Parasite assemblage Prevalence

AndroidCare: A Simple and low Cost Assisted living Solution

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Journal of Biomedical Science and Engineering 2016年第10期9卷 20-28页

作者： Abraham Otero alejandro Escario david G. Márquez Gabriel Caffarena Rodrigo garcía-Carmona Ana Iriarte Rafael Raya Department of Information Systems Engineering University San Pablo CEU Madrid Spain

Population aging places a growing stress on society’s resources. There is a need for Assisted living (Al) technologies that allow the elderly to live independently as long as possible. The AndroidCare open source project aims to explore what functionality can be provided in a low cost Al solution where no professional health organization is involved in the deployment or maintenance of the solution, nor in supervising the pa-tient;all these tasks are carried out by a relative of the elder. Therefore, in the system’s design simplicity of use has prevailed over having a lot of features. It is based on stan-dard off-the-shell commodity hardware (a smartphone) and it provides 1) assistance to the elder in complying with the treatment of chronic diseases;2) monitors and alerts of the occurrence of risk situations such as falls;and 3) simplifies the supervision of the elder’s therapy and behavior by the caregiver.

关键词： Assisted living Aging Chronic Diseases Behavior Monitoring

First record of Mayamontana coccolobae(Stephanosporaceae:Agaricales)from Mexico

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Studies in Fungi 2018年第1期3卷 34-38页

作者： de la Fuente JI Guevara-Guerrero G lópez CY garcía-Jiménez J Instituto Tecnológico de Ciudad Victoria.Blv.Emilio Portes Gil#1301Pte.CP87010 Cd VictoriaTamaulipasMéxico Instituto Tecnológico de Chetumal.Av.Insurgentes#330 Col.David G.GutiérrezC P 77013ChetumalQ.RooMéxico

Mayamontana coccolobae Castellano,Trappe and lodge is described for the first time from Mexico and the second time *** is characterized by the orange,subhypogeous basidiomata and the wrinkled subglobose spores with conspicuous hilar *** is not a very common species in the region and is recorded from disturbed lowland forest and urban *** coccolobae was only known from the type locality but now extends its geographical distribution to southeast Mexico.

关键词： Macrofungi Truffles Truffle-like Fungi Yucatán Peninsula

The intracellular signalosome of PD-l1 in cancer cells

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Signal Transduction and Targeted Therapy 2018年第1期3卷 72-80页

作者： david Escors Maria Gato-Canas Miren Zuazo Hugo Arasanz María Jesus garcía-Granda Ruth Vera Grazyna Kochan Navarrabiomed Complejo Hospitalario de NavarraIdISNAIrunlarrea 331008 PamplonaNavarraSpain Rayne Institute Division of Infection and ImmunityUniversity College London5 University StreetWC1E 6JF LondonUK Oncology Department Complejo Hospitalario de NavarraIdISNAIrunlarrea 331008 PamplonaNavarraSpain

Programmed cell death-1 ligand-1(PD-l1)overexpression in cancer cells accelerates tumor ***-l1 possesses two main pro-oncogenic ***,PD-l1 is a strong immunosuppressive molecule that inactivates tumor-specific T cells by binding to the inhibitory receptor ***,PD-l1 function relies on the delivery of intrinsic intracellular signals that enhance cancer cell survival,regulate stress responses and confer resistance toward pro-apoptotic stimuli,such as ***,we review the current knowledge on intracellular signal transduction pathways regulated by PD-l1,describe its associated signalosome and discuss potential combinations of targeted therapies against the signalosome with PD-l1/PD-1 blockade therapies.

关键词： cancer targeted signal

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中国户籍登记系统漏登合成估计方法研究

系统科学与数学 2024年

作者：黄艳华 lópez-carr david 胡桂华重庆工商大学成渝地区双城经济圈建设研究院 University of California Santa Barbara Department of Geography 重庆工商大学数学与统计学院统计智能计算与监测重庆市重点实验室

中国户籍登记系统存在漏登人口问题,但政府部门尚未开展户籍漏登估计工作.联合国统计司建议各国采用的单重漏登估计量未覆盖全部漏登人口,低估漏登率.本文提出用合成漏登估计量替代单重漏登估计量,并通过案例研究,比较了合成漏登估计量... 详细信息

中国户籍登记系统存在漏登人口问题,但政府部门尚未开展户籍漏登估计工作.联合国统计司建议各国采用的单重漏登估计量未覆盖全部漏登人口,低估漏登率.本文提出用合成漏登估计量替代单重漏登估计量,并通过案例研究,比较了合成漏登估计量与单重漏登估计量.实证研究结果表明:四种合成漏登估计量估计的漏登率均高于单重漏登估计量;除其中一种合成漏登估计量估计的漏登率的抽样标准差略高于单重漏登估计量外,其他三种合成漏登估计量估计结果的抽样标准差均小于单重漏登估计量.研究结果为统计局和公安部未来制定户籍登记系统漏登估计方案提供重要参考,提高方案的科学性和可操作性.

关键词：抽样调查事后分层三系统估计量刀切法

Artificial intelligence for early detection of pancreatic adenocarcinoma: The future is promising

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World Journal of Gastroenterology 2021年第13期27卷 1283-1295页

作者： Antonio Mendoza ladd david l Diehl Department of Internal Medicine Division of GastroenterologyTexas Tech University Health Sciences Center El PasoEl PasoTX 79905United States Department of Gastroenterology and Nutrition Geisinger Medical CenterDanvillePA 17822United States

Pancreatic ductal adenocarcinoma(PDAC) is a worldwide public health concern. Despite extensive research efforts toward improving diagnosis and treatment, the 5-year survival rate at best is approximately 15%. This dismal figure can be attributed to a variety of factors including lack of adequate screening methods, late symptom onset, and treatment resistance. Pancreatic ductal adenocarcinoma remains a grim diagnosis with a high mortality rate and a significant psychological burden for patients and their families. In recent years artificial intelligence(AI) has permeated the medical field at an accelerated pace, bringing potential new tools that carry the promise of improving diagnosis and treatment of a variety of diseases. In this review we will summarize the landscape of AI in diagnosis and treatment of PDAC.

关键词： Pancreatic adenocarcinoma Artificial intelligence Neural network Future perspectives Early diagnosis Improved performance

Objective assessment of the effect of pupil size upon the power distribution of multifocal contact lenses

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International Journal of Ophthalmology(English edition) 2017年第1期10卷 103-108页

作者： Eleni Papadatou Antonio J.Del Aguila-Carrasco Jose J.Esteve-Taboada david Madrid-Costa alejandro Cervino-Exposito Optometry Research Group University of ValenciaValencia 46100Spain Optics Ⅱ Department Optics and Optometry FacultyComplutense University of MadridMadrid 28037Spain

AIM： To analytically assess the effect of pupil size upon the refractive power distributions of different designs of multifocal contact ***： Two multifocal contact lenses of center-near design and one multifocal contact lens of center-distance design were used in this study. Their power profiles were measured using the NIMO TR1504 device （lAMBDA-X, Belgium）. Based on their power profiles, the power distribution was assessed as a function of pupil size. For the high addition lenses, the resulting refractive power as a function of viewing distance （far, intermediate, and near） and pupil size was also ***： The power distribution of the lenses was affected by pupil size differently. One of the lenses showed a significant spread in refractive power distribution, from about ？3 D to 0 D. Generally, the power distribution of the lenses expanded as the pupil diameter became greater. The surface of the lens dedicated for each distance varied substantially with the design of the ***： In an experimental basis, our results show how the lenses power distribution is affected by the pupil size and underlined the necessity of careful evaluation of the patient’s visual needs and the optical properties of a multifocal contact lens for achieving the optimal visual outcome.

关键词： multifocal contact lenses pupil size power profiles refractive power distribution