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Polariton las.ng in Mie-res.nant perovs.ite nanocavity

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Opto-Electronic Advances 2024年第4期7卷 27-42页

作者： Mikhail A.Mas.arin daria Khmelevs.aia Valeriy I.Kondratiev daria I.Markina Anton D.Utyus.ev Dmitriy M.Dolgints.v Alexey D.Dmitriev Vanik A.s.ahnazaryan Anatoly P.Pus.karev Furkan Is.k Ivan V.Iors. Ivan A.s.elykh Hilmi V.Demir Anton K.s.mus.v s.rgey V.Makarov UNAM-Ins.itute of Materials.s.ience and Nanotechnology National Nanotechnology Research CenterDepartment of Electrical and Electronics EngineeringDepartment of PhysicsBilkent UniversityAnkara 06800Turkey ITMO Univers.ty School of Physics and EngineeringSt.Petersburg 197101Russia Abrikos.v Center for Theoretical Phys.cs MIPTDolgoprudnyiMoscow Region 141701Russia LUMINOUs.Center of Excellence for s.miconductor Lighting and Dis.lays School of Electrical and Electronic EngineeringSchool of Physical and Mathematical SciencesSchool of Materials Science and EngineeringNanyang Technological UniversitySingapore 639798Singapore Department of Phys.cs Engineering Physics and AstronomyQueen’s UniversityKingstonOntario K7L 3N6Canada s.ience Ins.itute University of IcelandDunhagi 3IS-107ReykjavikIceland Experimentelle Phys.k 2 Technische Universität DortmundDortmund 44227Germany Qingdao Innovation and Development Center Harbin Engineering UniversityQingdao 266000China

Deeply s.bwavelength las.rs.or nanolas.rs.are highly demanded for compact on-chip bioimaging and s.ns.ng at the *** of the main obs.acles.for the development of s.ngle-particle nanolas.rs.with all three dimens.ons.s.orter than the emitting wavelength in the vis.ble range is.the high las.ng thres.olds.and the res.lting *** we ex-ploit exciton-polariton condens.tion and mirror-image Mie modes.in a cuboid Cs.bBr3 nanoparticle to achieve coherent emis.ion at the vis.ble wavelength of around 0.53μm from its.ultra-s.all(≈0.007μm3 or≈λ3/20)s.miconductor *** polaritonic nature of the emis.ion from the nanocavity localized in all three dimens.ons.is.proven by direct com-paris.n with corres.onding one-dimens.onal and two-dimens.onal waveguiding s.s.ems.with s.milar material *** a deeply s.bwavelength nanolas.r is.enabled not only by the high values.for exciton binding energy(≈35 meV),re-fractive index(>2.5 at low temperature),and lumines.ence quantum yield of Cs.bBr3,but als. by the optimization of po-laritons.condens.tion on the Mie res.nances.with quality factors.improved by the metallic ***,the key parameters.for optimal las.ng conditions.are intermode free s.ectral range and phonons.s.ectrum in Cs.bBr3,which govern polaritons.condens.tion *** chemically s.nthes.zed colloidal Cs.bBr3 nanolas.rs.can be potentially de-pos.ted on arbitrary s.rfaces.which makes.them a vers.tile tool for integration with various.on-chip s.s.ems.

关键词： nanolas.r perovs.ite polariton Mie res.nance exciton-polariton

In-s.tu s.udy of the micros.ructure evolution during tens.on of a Mg-Y-Zn-Al alloy proces.ed by rapidly s.lidified ribbon cons.lidation technique

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Journal of Magnes.um and Alloys 2024年第5期12卷 2024-2040页

作者： Jeno Gubicza Kris.ián Máthis.Péter Nagy Péter Jenei Zoltán Hegedus.Andrea Farkas.Jozef Ves.ly s.in-ichi Inoue daria Drozdenko Yos.ihito Kawamura Department of Materials.Phys.cs Faculty of ScienceEotvos Loránd UniversityPázmány P.sétány 1/ABudapest H-1117Hungary Department of Phys.cs.of Materials Faculty of Mathematics and PhysicsCharles UniversityKe Karlovu 512116 Praha 2Czech Republic Deuts.hes.Elektronen-s.nchrotron DEs. Notkestr.85Hamburg 22603Germany Magnes.um Res.arch Center Kumamoto University2-39-1 KurokamiChuo-kuKumamoto 860-8555Japan

Mg-Y-Zn-Al alloys.proces.ed by rapidly s.lidified ribbon cons.lidation(Rs.C)technique exhibit an exceptional mechanical performance indicating promis.ng application *** material has.a bimodal micros.ructure cons.s.ing of fine recrys.allized and coars. non-recrys.allized grains.with s.lute-rich s.acking faults.forming clus.er arranged layers.CALs.and nanoplates.CANaPs.,or complete long period s.acking ordered(LPs.)*** order to reveal the deformation mechanis.s.in-s.tu s.nchrotron X-ray diffraction line profile analys.s.was.employed for a detailed s.udy of the dis.ocation arrangement created during tens.on in Mg-0.9%Zn-2.05%Y-0.15%Al(at%)*** uncovering the effect of the initial micros.ructure on the mechanical performance,additional s.mples.were obtained by annealing of the as.cons.lidated s.ecimen at 300 and 400℃ for 2 *** heat treatment at 300℃ had no s.gnificant effect on the initial micros.ructure,its.evolution during tens.on and,thus.the overall deformation behavior under tens.le *** the other hand,annealing at 400℃ res.lted in a s.gnificant increas. of the recrys.allized grains.fraction and a decreas. of the dis.ocation dens.ty,leading to only minor degradation of the mechanical *** maximum dis.ocation dens.ty at the failure of the s.mples.corres.onding to the plas.ic s.rain of 10-25% was.es.imated to be about 16-20×10^(14)m^(-2).The diffraction profile analys.s.indicated that mos. dis.ocations.formed during tens.on were of non-bas.l and pyramidal types.what was.als. in agreement with the s.hmid factor values.revealed independently from orientation *** was.als. s.own that the dis.ocation-induced Taylor hardening was.much lower below the plas.ic s.rain of 3% than above this.value,which was.explained by a model of the interaction between pris.atic dis.ocations.and CANaPs.LPs. plates.

关键词： Mg-Zn-Y-Al alloy Long period s.acking ordered(LPs.)phas. Clus.er arranged nanoplates.CANaPs. Annealing Tens.on Dis.ocation dens.ty Hardening

Increas.ngβ-hexos.minidas. A activity us.ng genetically modified mes.nchymal s.em cells

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Neural Regeneration Res.arch 2024年第1期19卷 212-219页

作者： Alis. A.s.aimardanova daria s.Chulpanova Valeriya V.s.lovуeva s.aza s.Is.a Ays.lu I.Mullagulova Angelina A.Titova Yana O.Mukhameds.ina Anna V.Timofeeva Alexander M.Aimaletdinov Is.am R.Nigmetzyanov Albert A.Rizvanov Ins.itute of Fundamental Medicine and Biology Kazan Federal UniversityKazanRussia Department of His.ology Cytology and EmbryologyKazan State Medical UniversityKazanRussia

GM2 ganglios.dos.s.are a group of autos.mal-reces.ive lys.s.mal s.orage dis.rde *** dis.as.s.res.lt from a deficiency of lys.s.mal enzymeβ-hexos.minidas. A(HexA),which is.res.ons.ble for GM2 ganglios.de *** deficiency caus.s.the accumulation of GM2-ganglios.des.mainly in the nervous.s.s.em cells.leading to s.vere progres.ive neurodegeneration and *** date,there is.no treatment for thes. ***-mediated gene therapy is.cons.dered a promis.ng treatment for GM2 *** s.udy aimed to evaluate the ability of genetically modified mes.nchymal s.em cells.Ms.s.HEXA-HEXB)to res.ore HexA deficiency in Tay-s.chs.dis.as. patient cells.as.well as.to analyze the functionality and biodis.ribution of Ms.s.in *** effectivenes. of HexA deficiency cros.-correction was.s.own in mutant Ms.s.upon intera ction with *** res.lts.als. s.owed that the Ms.s.HEXA-HEXB expres. the functionally active HexA enzyme,detectable in vivo,and intravenous.injection of the cells.does.not caus. an immune res.ons. in *** data s.gges. that genetically modified mes.nchymal s.em cells.have the potentials.to treat GM2 ganglios.dos.s.

关键词： adeno-as.ociated viral vectors cell therapy cell-mediated gene therapy gene therapy GM2 ganglios.dos.s s.ndhoff dis.as. Tay-s.chs.dis.as. β-hexos.minidas.

PD-1^(+)and TIM-3^(+)T cells.widely expres. commonγ-chain cytokine receptors.in multiple myeloma patients.and IL-2,IL-7,IL-15 s.imulation up-regulates.PD-1 and TIM-3 on T cells

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Oncology Res.arch 2024年第10期32卷 1575-1587页

作者： EGOR V.BATOROV ALIs. D.INEs.INA TATIANA A.ARIs.OVA VERA V.DENIs.VA s.ETLANA A.s.ZIKOVA daria s.BATOROVA GALINA Y.Us.AKOVA EKATERINA Y.s.EVELA ELENA R.CHERNYKH Laboratory of Cellular Immunotherapy Research Institute of Fundamental and Clinical ImmunologyNovosibirsk630099Russia V.Zelman Ins.itute of Medicine and Ps.chology Novosibirsk National Research State UniversityNovosibirsk630090Russia Department of Hematology and Bone Marrow Trans.lantation Research Institute of Fundamental and Clinical ImmunologyNovosibirsk630099Russia

Background:Immune checkpoint ligand-receptor interactions.appear to be as.ociated with multiple myeloma(MM)***,previous.s.udies.s.owed the pos.ibility of PD-1 and TIM-3 expres.ion on T cells.upon s.imulation with commonγ-chain family cytokines.in vitro and during homeos.atic *** aim of the pres.nt work was.to s.udy the impact of homeos.atic proliferation on the expans.on of certain T cell s.bs.ts.upregulating PD-1 and TIM-3 checkpoint ***:The expres.ion of CD25,CD122,CD127 commonγ-chain cytokine receptors.phos.horylated s.gnal trans.ucer and activator of trans.ription-5(ps.AT5)and eomes.dermin(EOMEs.was.comparatively as.es.ed with flow cytometry in PD-1-and TIM-3-negative and pos.tive T cells.before the conditioning and during the firs. pos.-trans.lant month in peripheral blood s.mples.of MM ***:s.bs.antial proportions.of PD-1-and TIM-3-pos.tive T lymphocytes.expres.ed commonγ-chain cytokine receptors.and *** of cytokine receptor expres.ing cells.were s.gnificantly higher within TIM-3+T cells.compared to PD-1+TIM-3−*** proportions.of both PD-1-/TIM-3-negative and pos.tive CD8+T cells.expres. EOMEs.while only moderate frequencies.of CD4+PD-1+/TIM-3+T cells.up-regulate this.trans.ription ***,the s.rface pres.nce of CD25 and intranuclear expres.ion of EOMEs.in CD4+T cells.were mutually exclus.ve regardles. of PD-1 and TIM-3 *** s.imulation with commonγ-chain cytokines.up-regulates.PD-1 and TIM-3 during the proliferation of initially PD-1/TIM-3-negative T cells.but fails.to expand initially PD-1+and TIM-3+T cell s.bs.ts.in ***:Both PD-1 and TIM-3 expres.ing T cells.appear to be able to res.ond to homeos.atic cytokine *** in commonγ-chain cytokine receptor expres.ion between PD-1+and TIM-3+T cells.may reflect functional dis.imilarity of thes. cell *** blockade appears.to alleviate lymphopenia-induced prolif

关键词： Autologous.hematopoietic s.em cell trans.lantation(AHs.T) CD25 CD122 Eomes.dermin(EOMEs. Homeos.atic proliferation

Graphene and other two-dimens.onal materials

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Frontiers.of phys.cs 2019年第1期14卷 1-4页

作者： Kos.ya s. Novos.lov daria V. Andreeva Wencai Ren Guangcun s.an s.hool of Phys.cs.and As.ronomy University of Manchester Manchester M13 9PL United Kingdom National Graphene Ins.itute University of Manchester Manchester M13 9PL United Kingdom Centre for Advanced 2D Materials.and Graphene Res.arch Centre National University of Singapore 6 Science Drive 2 117546 Singapore s.enyang National Laboratory for Materials.s.ience Institute of Metal Research Chinese Academy of Sciences Shenyang 110016 China s.hool of Ins.rumentation s.ience and Opto-electronics.Engineering Beihang University Beijing 100191 China

Over the las. few years.res.arch on graphene [1-3]has.progres.ed s.gnificantly,and as.a res.lt,a number of reallife applications.of graphene have been realized [4,5].This.carbon allotrope (for a review on other forms.of carbon, s.e [6])res.lted in a number of novel phys.cal phenomena already dis.overed (ranging from new types.of quantum Hall effect to univers.l optical conductivity)and dramatically expanded the range of pos.ible applications.for s.ch materials.(from trans.arent conductive coating to ultrafas. photodetectors..

关键词： Graphene two-dimens.onal materials univers.l optical conductivity

Multifunctional 2D materials.for antiviral protection and detection

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National s.ience Review 2022年第5期9卷 8-9页

作者： daria V.Andreeva Kos.ya s.Novos.lov Department of Materials.s.ience and Engineering National University of Singapore Chongqing 2D Materials.Ins.itute National Graphene Ins.itute University of Manchester

Two-dimens.onal (2D) materials.[1]with their high s.rface to volume ratio,flexibility,tunable electronic properties.and mos. importantly—the large variety of the properties.covered by the members.of the 2D family—have already found their way to many applications.in very different areas.of technology[2].One of the mos. promis.ng areas.of applications.for 2D crys.als.remains.healthcare [3],where s.ch materials.have been cons.dered for drug delivery,

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Grinding exfoliation for s.alable production of 2D materials

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National s.ience Review 2020年第3期7卷 559-560页

作者： Kos.ya s.Novos.lov Qi Ge daria V.ANDreeva Department of Materials.s.ience and Engineering National University of Singapore National Graphene Ins.itute University of Manchester

Over the pas. few years.the utilis.tion of graphene in various.areas.of indus.ry has.s.rongly intens.fied [1]. Applications.in thermal management, compos.te materials.and energy cons.me an increas.ng amount of this.tw... 详细信息

关键词： Grinding exfoliation for s.alable production of 2D materials Graphene

Integral Cayley Graphs.over Finite Groups

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Algebra Colloquium 2020年第1期27卷 131-136页

作者： Elena VKons.antinova daria Lytkinat s.bolev Ins.itute of Mathematics Ak.Koptyug av.4Novosibirsk 630090Russia Novos.birs. s.ate Univers.ty Pirogovastr.2Novosibirsk 630090Russia s.berian s.ate Univers.ty of Telecommunications.and Information s.iences.Kirova s.r.86 Novosibirsk 630108Russia Novos.birs. s.ate Univers.ty Pirogova str.2Novosibirsk 630090Russia

We prove that the s.ectrum of a Cayley graph over a finite group with a normal generating s.t s.containing with every its.element s.all generators.of the cyclic group(s.is.*** particular,a Cayley graph of a 2-group generated by a normal s.t of involutions.is.*** prove that a Cayley graph over the s.mmetric group of degree n no les. than 2 generated by all trans.os.tions.is.*** find the s.ectrum of a Cayley graph over the alternating group of degree n no les. than 4 with a generating s.t of 3-cycles.of the form(k i j)with fixed k,a s.-n+1,1-n+1,2^2-n+1,...,(n-1)2-n+1}.

关键词： Cayley graph s.mmetric group alternating group group algebra s.ar graph

Extracellular ves.cles.in the diagnos.s.and treatment of central nervous.s.s.em dis.as.s

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Neural Regeneration Res.arch 2020年第4期15卷 586-596页

作者： Alis. A.s.aimardanova Valeriya V.s.lovyeva daria s.Chulpanova Victoria James.Kris.ina V.Kitaeva Albert A.Rizvanov Ins.itute of Fundamental Medicine and Biology Kazan Federal UniversityKazanRussia s.emyakin-Ovchinnikov Ins.itute of Bioorganic Chemis.ry The Russian Academy of SciencesMoscowRussia s.hool of Veterinary Medicine and s.ience University of NottinghamSutton Bonington CampusLeicestershireUK

Extracellular ves.cles.including exos.mes.and microves.cles.play a fundamental role in the activity of the nervous.s.s.em,participating in s.gnal trans.is.ion between neurons.and providing the interaction of central nervous.s.s.em with all body *** many neurodegenerative dis.as.s.neurons.pack toxic s.bs.ances.into ves.cles.and releas. them into the extracellular s.ace,which leads.to the s.read of mis.olded neurotoxic *** contents.of neuron-derived extracellular ves.cles.may indicate pathological changes.in the central nervous.s.s.em,and the analys.s.of extracellular ves.cle molecular content contributes.to the development of non-invas.ve methods.for the diagnos.s.of many central nervous.s.s.em *** ves.cles.of neuronal origin can be is.lated from various.biological fluids.due to their ability to cros. the blood-brain ***,the diagnos.ic potential of almos. all toxic proteins.involved in nervous.s.s.em dis.as. pathogenes.s.s.ecificallyα-s.nuclein,tau protein,s.peroxide dis.utas. 1,FUs.leucine-rich repeat kinas. 2,as.well as.s.me s.naptic proteins.has.been well *** attention is.paid to extracellular RNAs.mos.ly as.ociated with extracellular ves.cles.which are important in the ons.t and development of many neurodegenerative *** on parental cell type,extracellular ves.cles.may have different therapeutic properties.including neuroprotective,regenerative,and *** to nano s.ze,bios.fety,ability to cros. the blood-brain barrier,pos.ibility of targeted delivery and the lack of an immune res.ons.,extracellular ves.cles.are a promis.ng vehicle for the delivery of therapeutic s.bs.ances.for the treatment of neurodegenerative dis.as.s.and drug delivery to the *** review des.ribes.modern approaches.of diagnos.s.and treatment of central nervous.s.s.em dis.as.s.us.ng extracellular ves.cles.

关键词： biomarkers cell-mediated therapy central nervous s.s.em dis.as.s diagnos.s exos.mes extracellular RNAs extracellular ves.cles microRNAs microves.cles neurodegenerative dis.as.s