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Accidental Ingestion of Petroleum in Children at the University Hospital of Brazzaville

Open Journal of Pediatrics 2021年第1期11卷 1-8页

作者： Engoba Moyen daniel kazi menga Verlem Bomelefa-Bomel Armel Landry Batchi-Bouyou Georges Moyen University Marien Ngouabi Brazzaville Congo Department of Intensive Care Pediatrics University Hospital of Brazzaville Brazzaville Congo Central Military Hospital Brazzaville Congo

Introduction: Petroleum ingestion is a health problem in Africa and can be responsible for significant mortality. Objectives: Improving the management of accidental petroleum ingestion in children, describe the socio-demographic characteristics, clinical, therapeutic and evolutionary profile of children hospitalized for accidental ingestion of petroleum and identify the factors associated with the occurrence of petroleum pneumopathy. Patients and Methods: We conducted a cross-sectional analytical study with retrospective collection from January 2016 to December 2015, i.e. in 24 months in the Pediatric Intensive Care and Infant Pediatrics departments at the University Hospital of Brazzaville. We included children who accidentally ingested petroleum. The variables studied were epidemiological, clinical, therapeutic, radiological and evolutionary. The statistical tests used were Pearson’s Chi2 and Odds ratio. The materiality threshold was set at 5%. Results: Out of 8013 children hospitalized, 78 (1%) had accidentally ingested petroleum, including 49 (62.8%) boys and 29 (37.3%) girls with an average age of 20 months. They were between 13 and 30 months old n = 44 (56.4%). The mothers were between 25 and 35 years old n = 49 (62.8%), no profes

关键词： Accidental Ingestion Petroleum Pneumopathy Children University Hospital of Brazzaville

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Effect of Hydro-ethanolic (1:1) Extract of Stephania Hernandifolia and Achyranthes Aspera in Composite Manner on Testicular Activity in Male Albino Rat:A Dose Dependent Analysis

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Journal of Reproduction and Contraception 2012年第4期23卷 209-221页

作者： daniel Paul kazi Monjur Ali Debidas Ghosh Dilip K.Nandi Hanéne Chenni Mohamed M.Trabelsi Department of Bio-Medical Laboratory Science & Management (UGC Innovative Programme Funded Department under Xth-5 years plan) Vidyasagar University Department of Physiology Raja N.L. Khan Women's College Laboratory of Histology and Embryology Faculty of Medicine

Objective To investigate the effect of hydro-ethanolic extraet of Stephania hernandifolia leaves and Aehyranthes aspera roots in composite manner at the ratio of 1：3 on testicular activity in male rats. Methods Rats were divided into 4 groups with 8 animals in each group. The control （group A） received 0. 5 ml of olive oil/100 g body weight orally, other three groups were treated with said extract orally at a dose of 0.4 mg/g （group B） or 0.8 mg/g （group C） or 1.6 mg/g body weight （group D） respectively for 28 d. On 29th day of experiment, the animals were sacrificed. Sperm concentrations in cauda epididymis and biochemical markers like testicular cholesterol, androgenic key enzyme activity, plasma testosterone level seminal fructose level, glutamate oxaloacetate transaminase （GOT） and glutamate pyruvate transaminase （GPT） activities and serum triglyceride levels were measured following standard methods. ResuIts Extract treated animals in all doses resulted in a significant （P〈O. 05）decrease in sperm concentration, testicular androgenic key enzyme activity, plasma testosterone and seminal vesicle fructose levels along with an increase in testieular cholesterol level Animals treated at a dose of O. 8 mg/g body weight showed more promising result without causing any metabolic toxicity compared with other doses. Histological study also supported the biochemical results. The minimum but most effective dose i.e. 0.8 mg/g body weight had an inhibitory effect on implantation focused here by mating *** The composite efficacy as male contraceptive extract of S. hernandifolia and A. aspera has a potent that may provide clues to the pharmaceutical industries for male contraceptive development

关键词： Achyranthes aspera Stephania hernandifolia testosterone seminiferous tubule

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