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Comparative Study between Endometrial Resection and Electrocoagulation in Patients with Abnormal Uterine Bleeding

Open Journal of Obstetrics and Gynecology 2017年第3期7卷 312-325页

作者： Leonardo Vieira Elias daniel Spadoto-Dias Nilton José Leite Flávia Neves Bueloni-Dias Gustavo Filipov Peres Carlos Roberto Padovani Rogério Dias Department of Gynecology and Obstetrics Botucatu Medical School S&atilde o Paulo State University—UNESP S&atilde o Paulo Brazil Department of Biostatistics Botucatu Institute of Biosciences S S&atilde o Paulo State University—UNESP S&atilde o Paulo Brazil The Gynecological Endoscopy and Family Planning Sector Botucatu Medical School Hospital S&atilde o Paulo State University—UNESP and Principal Investigator S&atilde o Paulo Brazil

Objective: To compare clinical outcomes between two first-generation endometrial ablation techniques. Design: Prospective comparative coorte. Setting: Tertiary public hospital, university teaching center. Seventy-three patients with abnormal uterine bleeding unresponsive to clinical treatment submitted to endometrial ablation from October 2011 to September 2013. Methods and Main Outcome Measures: Patients were assigned to either monopolar U-shaped electrode resection with rollerball electrocoagulation (group A, n = 36) or rollerball electrocoagulation alone (group B, n = 37). Mean follow-up length was 359 (280 - 751) and 370 days (305 - 766) in groups A and B, respectively. Bleeding pattern, associated symptoms, failure/success rates were assessed 30, 90, 180 and 360 days post-procedure. Findings: Patient characteristics were similar in both groups (P ≥ 0.05). Surgery duration (mean of 48.5 [±12.0] vs. 31.9 [±5.6] min, P Conclusions: Endometrial ablation using rollerball electrocoagulation alone may be considered safer than resection with rollerball electrocoagulation, which requires shorter surgical time and less distention medium, and is associated with lower postoperative vaginal discharge incidence. Success rate did not statistically differ between groups, but study parameters in absolute values and percents were superior in group B.

关键词： Uterine Bleeding Hysteroscopy Surgical Procedures Endometrial Ablation Techniques Patient Satisfaction

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Kikuchi-Fujimoto Disease Associated to the Epstein-Barr Virus. A Type of Rare Necrotizing Lymphadenitis and Its Differential Diagnosis

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Open Journal of Pathology 2013年第4期3卷 186-192页

作者： Mónica Belinda Romero Guadarrama Oscar daniel Guzmán-Aguilar Adriana Carolina López-Ugalde José Samuel Almeida Navarro Humberto Cruz-Ortíz Unidad de Patología Hospital General de México “Dr. Eduardo Liceaga” México D.F. México

Introduction: Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a specific and self-limited disease;its etiology is unknown. Some causal microorganisms have been proposed. The objective of the present article is to emphasize the clinicopathological characteristics of this disease that has been associated to the Epstein-Barr virus and to compare the histological changes with other types of necrotizing lymphadenopathies. Material and Methods: We studied 32 patients of the Surgical Pathology Service with necrotizing lymphadenitis, diagnosed in the years from 2004 to 2012 to found more cases of this rare disease in our Institution. Patients were 18 women and 14 men with an average age of 37 years. Results: The lymph nodes were cervical and axillary ones, some were associated to autoimmune diseases and no cause was identified in others. One of the cases, was diagnosed as KFD, presented morphological changes characteristic of this disease, such as subcapsular lymphoid follicles, zones with cell debris, epithelioid macrophages, clear-cytoplasm histiocytes, and immunoblast-reactive lymphocytes. Immunohistochemical markers were determined, such as CD20, CD2, CD4, CD8, CD68, lysozyme, CD56, granzyme B and EBER, which demonstrated the presence of B, T lymphocytes, histiocytes and cells positive to EBER. Histological changes in KFD occurred in three stages: proliferative stage, necrotizing, and xanthomatous. It is important to identify the histological stages of the disease because a differential diagnosis must be performed in regard to lymphadenopathies with necrosis and diverse types of lymphomas. Conclusion: We present a case of necrotizing lymphadenitis (KFD) associated to the Epstein-Barr virus and in some cases it is not possible to render a specific diagnosis based on morphologic findings, alone, and a diagnosis of necrotizing lymphadenitis may be used.

关键词： Kikuchi-Fujimoto Disease Epstein Barr Virus

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Balanced propofol sedation administered by nonanesthesiologists:The first Italian experience

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World Journal of Gastroenterology 2011年第33期17卷 3818-3823页

作者： Alessandro Repici Nico Pagano Cesare Hassan Alessandra Carlino Giacomo Rando Giuseppe Strangio Fabio Romeo Angelo Zullo Elisa Ferrara Eva Vitetta daniel de Paula Pessoa Ferreira Silvio Danese Massimo Arosio Alberto Malesci Department of Gastroenterology IRCCS Istituto Clinico HumanitasVia Manzoni 5620089 RozzanoMilanItaly Department of Anaesthesiology IRCCS Istituto Clinico HumanitasVia Manzoni 5620089 RozzanoMilanItaly

AIM:To assess the efficacy and safety of a balanced approach using midazolam in combination with propofol,administered by nonanesthesiologists,in a large series of diagnostic ***:Consecutive patients undergoing diagnostic colonoscopy were sedated with a single dose of midazolam(0.05 mg/kg)and lowdose propofol(starter bolus of 0.5 mg/kg and repeated boluses of 10 to 20 mg).Induction time and deepest level of sedation,adverse and serious adverse events,as well as recovery times,were prospectively *** intubation and adenoma detection rates were also ***:Overall,1593 eligible patients were *** median dose of propofol administered was 70 mg(range:40120 mg),and the median dose of midazolam was 2.3 mg(range:24 mg).Median induction time of sedation was 3 min(range:14 min),and median recovery time was 23 min(range:1040 min).A moderate level of sedation was achieved in 1561(98%) patients,whilst a deep sedation occurred in 32(2%) *** oxygen desaturation requiring further oxygen supplementation occurred in 8(0.46%;95% CI:0.2%0.8%)*** serious adverse event was *** intubation and adenoma detection rates were 93.5%and 23.4%(27.8%for male and 18.5%for female,subjects),***:A balanced sedation protocol provided a minimalization of the dose of propofol needed to target a moderate sedation for colonoscopy,resulting in a high safety profile for nonanesthesiologist propofol sedation.

关键词： Colonoscopy Propofol Sedation

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Renal Anastomosing Hemangioma Simulating Angiosarcoma as a Second Primary in a Patient with Breast Cancer

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Open Journal of Urology 2021年第12期11卷 466-473页

作者： daniel Fernando Méndez López Jhonatan Gómez Domínguez Jorge Antonio Rojas González Marco Antonio Ortiz Jiménez Omar Santos Moreno Department of Radiology in the Governmental Hospital “Hospital de Especialidades 5 de Mayo” (ISSSTEP) Puebla Mexico

Anastomosing hemangioma is a type of tumor lesion of benign behavior scarcely documented, it has been observed in renal parenchyma, testicles, ovaries and adrenal glands, it is usually prone to perirenal and renal medullary adipose tissue. In this case report, we present an anastomosed hemangioma in the right kidney of a 33-year-old woman, with previous coexistence of breast cancer, in which an unusual behavior was detected, with characteristics of vascular lesion, in this case we report: The classic conditions, its heterogeneous nature and the vascular alterations that presents in different imaging modalities.

关键词： Anastomosing Hemangioma Kidney Tumor Lesion Breast Cancer

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Perigeniculate arachnoid cysts and CSF fistulae of the fallopian canal:Histopathologic correlates of a rare clinical entity

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2021年第2期7卷 71-81页

作者： Emerson E.Lee Nicholas S.Andresen Bryan McKenzie Jeffrey D.Sharon Howard W.Francis daniel Q.Sun Department of Otolaryngology-Head and Neck Surgery Johns Hopkins UniversityUSA Inova Fairfax Hospital USA Deportment of Otolaryngology-Head and Neck Surgery University of California Son FranciscoUSA Department of Head and Neck Surgery and Communication Sciences Duke UniversityUSA

Cerebrospinal fluid(CSF)fistulae originating from the fallopian canal of the facial nerve is hypothesized to arise due to atypical patterns of subarachnoid space extension into the geniculate ganglion or more distal regions along the intratemporal course of the facial nerve,but its pathogenesis remains poorly *** a rare etiology of CSF fistulae of the temporal bone,there are significant clinical ramifications due to the risk of recurrent meningitis,difficulty in identifying the anatomic location of the CSF leak,and technical challenges associated with surgical *** present three clinical cases of arachnoid cysts within the geniculate fossa with or without CSF fistulization and provide histopathologic correlates of this rare clinical phenomenon from a human temporal bone *** pediatric and adult patients presented suggest differential pathophysiologic mechanisms associated with CSF *** bone histology reveals atypical patterns of subarachnoid space extension in the fallopian canal that may underlie arachnoid cyst formation and overt CSF leak from the geniculate region.

关键词： Geniculate ganglion Arachnoid cyst Fallopian canal Facial nerve Cerebrospinal fluid otorrhea Cerebrospinal fluid leak Subarachnoid space

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垄断地位的维持:美国政府控微软案

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山东大学学报（哲学社会科学版） 2008年第3期 15-27页

作者：丹尼尔.L.鲁宾费尔德美国司法部

微软案的核心是美国政府声称微软采取了一系列反竞争行为,其目的是保持其在操作系统(OS)市场上的垄断。美国政府并没有质疑微软历史上成功的根源,但是声称,微软的行为使消费者受到了损害,部分原因是因为消费者需要为操作系统支付更高的... 详细信息

微软案的核心是美国政府声称微软采取了一系列反竞争行为,其目的是保持其在操作系统(OS)市场上的垄断。美国政府并没有质疑微软历史上成功的根源,但是声称,微软的行为使消费者受到了损害,部分原因是因为消费者需要为操作系统支付更高的价钱,部分原因是因为微软的行为减少了软件行业的创新。而作为回应,微软则辩解道,在一个高速发展的产业中,它面临的是十分严峻的竞争威胁,因此并不存在垄断。它进一步辩解道,微软的成功应被视为是促进竞争的,因为从它的高质量创新型软件分销中,消费者得到了利益。如果法院强行实施反托拉斯纠正,微软相信,竞争的激励将会减少,并会导致更少的而不是更多的创新。

关键词：反垄断美国司法部微软

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Induced Hall-Like Current by Acoustic Phonons in Semiconductor Fluorinated Carbon Nanotube

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World Journal of Condensed Matter Physics 2020年第2期10卷 71-87页

作者： daniel Sakyi-Arthur Samuel Y. Mensah Kofi W. Adu Kwadwo A. Dompreh Raymond Edziah Natalia G. Mensah Cynthia Jebuni-Adanu Department of Physics College of Agriculture and Natural Sciences U.C.C Ghana Department of Mathematics College of Agriculture and Natural Sciences U.C.C Ghana Department of Physics Pennsylvania State University-Altoona College Altoona Pennsylvania USA Material Research Institute Pennsylvania State University University Park Pennsylvania USA St. Francis College of Education Hohoe Volta Region Ghana

We show that Hall-like current can be induced by acoustic phonons in a nondegenerate, semiconductor fluorine-doped single-walled carbon nanotube (FSWCNT) using a tractable analytical approach in the hypersound regime ?(q is the modulus of the acoustic wavevector and is the electron mean free path). We observed a strong dependence of the Hall-like current on the magnetic field, H, the acoustic wave frequency, , the temperature, T, the overlapping integral, , and the acoustic wavenumber, q. Qualitatively, the Hall-like current exists even if the relaxation time does not depend on the carrier energy but has a strong spatial dispersion, and gives different results compared to that obtained in bulk semiconductors. For and , the Hall-like current is in the absence of an electric field and in the presence of an electric field at 300 K. Similarly, the surface electric field due to the Hall-like current is in the absence of an external electric field. In the presence of an external electric field, and for at 300 K. q and can be used to tune the Hall-like current and of the FSWCNT. This offers the potential for room temperature application as an acoustic switch or transistor, as well as a material for ultrasound current source density imaging (UCSDI) and AE hydrophone device in biomedical engineering.

关键词： Carbon Nanotube Fluorinated Hall-Like Current Cyclotron

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Are Tuberculosis Patients Managed According to the National Guidelines in Lagos State Nigeria?

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International Journal of Clinical Medicine 2016年第1期7卷 16-24页

作者： Olusola Adedeji Adejumo Olusoji James daniel Mustapha Gidado Andrew Folarin Otesanya Esther Ngozi Adejumo Ebunoluwa O. Jaiyesimi Oluwatoyin Esther Idowu Olumuyiwa O. Odusanya Department of Community Health and Primary Health Care Lagos State University Teaching Hospital Ikeja Lagos Nigeria Department of Community Medicine and Primary Care Olabisi Onabanjo University Teaching Hospital Sagamu Nigeria KNCV Tuberculosis Foundation/TB CARE I Project Abuja Nigeria Medical Services Department Central Bank of Nigeria Lagos Nigeria Department of Medical Laboratory Science Babcock University Ilisan-Remo Nigeria Department of Community Health and Primary Health Care College of Medicine Lagos Lagos State University Lagos Nigeria

Setting: Private and public tuberculosis (TB) treatment centers in Lagos State, Nigeria. Objective: To compare adherence of private and public providers of directly observed treatment short course (DOTS) in the Lagos State TB control program, Nigeria (LSTBLCP) with the national TB guidelines. Design: A retrospective review of treatment cards of TB patients managed within the first and second quarter of 2012 in 34 DOTS facilities {23 public, 7 private for profit (PFP), and 4 private not for profit (PNFP)} involved in the private public mix of the LSTBLCP. Results: Of the 1896 treatment cards reviewed, 1524 (80.4%), 132 (7.0%) and 240 (12.6%) were from public, PFP and PNFP DOTS facilities, respectively. About 19%, 25% and none of the patients managed at the public, PNFP, and PFP DOTS facilities were treated in full adherence with the national guidelines respectively. A significantly higher proportion of adults and sputum smear positive TB patients were treated in full adherence with the national guidelines (p < 0.05). Treatment success was associated with full adherence with the national guidelines. Conclusion: There is a need to reorient health care providers in public and private health facilities in Lagos State Nigeria to ensure full adherence with the national TB guidelines.

关键词： Adherence National Guidelines Health Workers DOTS Facilities

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低频反隐身技术的发展

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国际航空 2016年第12期 59-62页

作者： daniel Katz 李悦霖瞿薇薛槐敏

随着数字电子技术的发展，低频雷达开始成为反隐身飞机的利器，那么，现在的隐身技术是否已经过时？

关键词：反隐身技术低频雷达数字电子技术隐身飞机

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科研伦理委员会是否应该监管报告偏倚？

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英国医学杂志中文版 2018年第10期21卷 600-602页

作者： Simon E Kolstoe, daniel R Shanahan 孙齐蕊(译) senior lecturer and ethics adviserInstitute of Biomedical and Biomolecular Science University of Portsmouth Health Sciences BioMed CentralLondon 北京协和医学院中国医学科学院北京协和医院社会医学与公共卫生管理学

赞成基于长期保留数据证据的失真会给患者带来伤害如果科学研究结果不能适当交流，那么科学应用所带来的进步也无法实现。这在试验对象通常为人类志愿者的医学领域里尤为重要。没有研究者的反馈，费用高昂的新兴创新就无法产生，但是基... 详细信息

赞成基于长期保留数据证据的失真会给患者带来伤害如果科学研究结果不能适当交流，那么科学应用所带来的进步也无法实现。这在试验对象通常为人类志愿者的医学领域里尤为重要。没有研究者的反馈，费用高昂的新兴创新就无法产生，但是基于长期隐瞒数据的证据偏倚，不管是为了经济效益还是只是疏忽，都将对患者带来危害。

关键词：委员会警察道德偏爱

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