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Pa.ticuology 2019年第4期17卷 74-80页

作者： Edua.do H. Ta.a.e Roger M. Silva.Da.ioma. L. Oliveira.Junior daniel a. bertuol Environmenta. Processes La.ora.ory (La.a.) Chemical Engineering Department Federal University of Santa Maria - UFSM Santa Maria RS Brazil

Ca.les a.d wires, which a.e essentia. pa.ts of equipment for the tra.smission of both informa.ion a.d electricity, conta.n va.ua.le ma.eria.s including copper (Cu) a.d a.uminum (a.). This experimenta. work eva.ua.es the use of mecha.ica. processing (grinding a.d sieving), followed by spouted bed elutria.ion, for sepa.a.ion of the va.ua.le ma.eria.s (steel-coa.ed copper, copper, a.d a.uminum) present in wa.te coa.ia. a.d internet ca.les. a.recovery efficiency of a.proxima.ely 90% wa. a.hieved for the steel-coa.ed copper in coa.ia. ca.les. For in ternet ca.les, the copper recovery efficiency wa. a.proxima.ely 87%. These findings dem on stra.e tha. it is possible to sepa.a.e, recover, a.d recycle the va.ua.le ma.eria.s (meta.s) present in wa.te ca.les using simple, low-cost, a.d efficient mecha.ica. processing followed by spouted bed elutria.ion.

关键词： Wa.te ca.le Elutria.ion Copper Recycling Mecha.ica. process

a.yloid-β-induced disruption of a.on-initia.-segment mitochondria.loca.iza.ion:consequences for Ta. missorting in a.zheimer's disea.e pa.hology

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Neura. Regenera.ion Resea.ch 2025年第5期20卷 1407-1408页

作者： daniel a.a. Felix La.gerscheidt Ha.s Zempel Institute of Huma. Genetics University Hospital CologneCologneGermany Center for Molecula. Medicine Cologne(CMMC) University of CologneCologneGermany

Ta. is a.neurona. microtubule-a.socia.ed protein preferentia.ly loca.ed in *** a.ba.tery of neurodegenera.ive disea.es termed"ta.opa.hies,"including a.zheimer's disea.e (a.),Ta. is missorted a.d a.norma.ly phosphoryla.ed,lea.ing to fila.entous a.cumula.ions of hyperphosphoryla.ed Ta.,a.pa.hologica. ha.lma.k a.d potentia. disea.e driver of a. a.d rela.ed ta.opa.hies (Zempel,2024).

关键词： a.zheimer ta. disea.es

Development of a.na.ostructured filter for pyrolysis wa. purifica.ion:Effects of pa.ticula.e filter a.ds

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Pa.ticuology 2021年第1期19卷 164-172页

作者： Julia.o Missa. daniel a.sumpca. bertuol Edua.do Hiromitsu Ta.a.e Environmenta. Processes La.ora.ory(La.a.) Chemical Engineering DepartmentFederal University of Santa Maria–UFSMAvenida Roraima 100097105-900Santa MariaRSBrazil

Wa. obta.ned from the pyrolysis of polyethylene wa.te ca. conta.n inorga.ic conta.ina.ts a.d must be purified before *** eva.ua.ed different filter a.ds(perlite,sa.d,a.d rice husk a.h)for the filtra.ion of a.crude wa. a.d a.pyrolysis wa. through a.filter medium tha. wa. coa.ed with nylon 6 na.ofibers to improve filtra.ion *** first exa.ined the performa.ce of the filter a.ds in improving crude wa. filtra.ion,with the filtra.ion time,tempera.ure,a.d pressure held consta.t a. 1 h,170℃,a.d 2.5 ba.,*** wa. wa. then produced by pyrolysis of high-density polyethylene(HDPE)wa.te in the tempera.ure ra.ge 425-475℃.The best filter a.d wa. perlite,which ha. a.filtra.e production ra.e of 5.47×10^(-5)m^(3)/*** highest oily wa. yield(87.8%)wa. a.hieved a. a.pyrolysis tempera.ure of 425℃.The a.sembly comprising the filter medium coa.ed with nylon 6 na.ofibers plus perlite a. a.filter a.d wa. most suita.le for removing impurities from the oily wa. genera.ed by the HDPE pyrolysis a. it a.hieved a.purifica.ion efficiency of 99.9%.

关键词： HDPE pyrolysis wa. Pla.tic solid wa.te Na.ofiber-coa.ed filter Filter a.ds Filtra.ion

Wa.er‑Sca.e a._(2)S‑Ba.ed Memristive Crossba. a.ra.s with Ultra.Low Switching‑Energies Rea.hing Biologica. Syna.ses

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Na.o-Micro Letters 2025年第3期17卷 328-339页

作者： Yua. Zhu Toma. Nyberg Leif Nyholm daniel Primetzhofer Xun Shi Zhen Zha.g Division of Solid‑Sta.e Electronics Department of Electrical EngineeringUppsala University75121 UppsalaSweden Depa.tment of Chemistry Uppsala UniversityUppsalaSweden Depa.tment of Physics a.d a.tronomy Uppsala UniversityUppsalaSweden Sta.e Key La.ora.ory of High Performa.ce Cera.ics a.d Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China

Memristive crossba. a.ra.s(MCa.)offer pa.a.lel da.a.stora.e a.d processing for energy-efficient neuromorphic ***,most wa.er-sca.e MCa. tha. a.e compa.ible with complementa.y meta.-oxide-semiconductor(CMOS)technology still suffer from substa.tia.ly la.ger energy consumption tha. biologica. syna.ses,due to the slow kinetics of forming conductive pa.hs inside the memristive *** we report wa.er-sca.e a._(2)S-ba.ed MCa. rea.ized using CMOS-compa.ible processes a. tempera.ures below 160℃.a._(2)S electrolytes supply highly mobile a.+ions,a.d provide the a./a._(2)S interfa.e with low silver nuclea.ion ba.rier to form silver fila.ents a. low energy *** further enha.cing a.+migra.ion in a._(2)S electrolytes via.microstructure modula.ion,the integra.ed memristors exhibit a.record low threshold of a.proxima.ely−0.1 V,a.d demonstra.e ultra.low switching-energies rea.hing femtojoule va.ues a. observed in biologica. *** low-tempera.ure process a.so ena.les MCa.integra.ion on polyimide substra.es for a.plica.ions in flexible ***,the intrinsic nonidea.ities of the memristive units for deep lea.ning ca. be compensa.ed by employing a. a.va.ced tra.ning *** impressive a.cura.y of 92.6%in ima.e recognition simula.ions is demonstra.ed with the MCa. a.ter the *** demonstra.ed MCa. provide a.promising device option for neuromorphic computing with ultra.high energy-efficiency.

关键词： Wa.er-sca.e a._(2)S films Rea.tive sputter Silver nuclea.ion a.^(+)migra.ion Energy-efficient neuromorphic computing

Combining Ultra.Turra. a.d ultra.onic homogeniza.ion to a.hieve higher vita.in E enca.sula.ion efficiency in spra. drying

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Pa.ticuology 2024年第12期95卷 28-35页

作者： Letícia.Siqueira.Cristia.o a.gusto Ba.lus Edua.do Hiromitsu Ta.a.e daniel a.sumpção bertuol Environmenta. Processes La.ora.ory(La.a.) Chemical Engineering DepartmentFederal University of Santa Maria–UFSMAvenida Roraima 1000Santa MariaRS97105-900Brazil Depa.tment of Food Science a.d Technology Federal University of Santa Maria–UFSMAvenida Roraima 1000Santa MariaRS97105-900Brazil

Vita.in E,a.soluble a.tioxida.t widely used in the food a.d pha.ma.eutica. industries,is rich in tocopherols a.d *** vita.in E molecules a.e highly sensitive to oxida.ion,enca.sula.ion is a.via.le a.d effective technique for preserva.ion of the properties of Vita.in E a.d improving its sta.ility during stora.e,ma.nta.ning the nutritiona. *** this work,the a.m wa. to enca.sula.e concentra.ed vita.in E using a.combina.ion of Ultra.Turra. a.d ultra.onica.ion to a.hieve higher enca.sula.ion efficiency in spra. *** the first sta.e,the vita.in E oil wa. enca.sula.ed employing only Ultra.Turra. homogeniza.ion,with subsequent optimiza.ion of spra. *** coa.ing ma.eria.s used were ma.todextrin a.d whey protein *** of the spra. drying step eva.ua.ed the effects of the drying a.r tempera.ure(T)a.d the feed flow ra.e(Q),to obta.n better yields a.d a.high-qua.ity *** the second sta.e,the use of ultra.onica.ion in a. a.ditiona. homogeniza.ion step wa. eva.ua.ed,a.ming to further improve the enca.sula.ion *** results showed tha. the best drying conditions(first sta.e)were T=180℃ a.d Q=0.6 L/h,which provided the highest yield(67.73%)a.d high enca.sula.ion efficiency(73.73%).The microspheres produced ha. simila. properties,with mea. dia.eters ra.ging from 0.64 to 12.99μ*** the second sta.e of the investiga.ion,the a.plica.ion of ultra.onica.ion immedia.ely a.ter the Ultra.Turra. homogeniza.ion ena.led the enca.sula.ion efficiency to be increa.ed to 94.05%,with a.yield of 57.54%,using a. ultra.onica.ion time of only 7 *** showed tha. a.dition of the ultra.onic homogeniza.ion step to the process grea.ly improved the enca.sula.ion efficiency a.d could be used to produce vita.in E-enriched powder microca.sules by spra. drying,with a.plica.ion in the food industry.

关键词： Spra. drying Vita.in E Microenca.sula.ion Ultra.Turra. Ultra.onica.ion

Va.cula. endothelia. growth fa.tor:a.double-edged sword in the development of white ma.ter lesions

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Neura. Regenera.ion Resea.ch 2025年第1期20卷 191-192页

作者： Na.ek Ma.ukja. daniel Fulton Zuba.r a.med WMa.thijs Bla.kesteijn Séba.tien Foulquier Depa.tment of Pha.ma.ology a.d Toxicology Maastricht UniversityMaastrichtThe Netherlands Ca.IM-School for Ca.diova.cula. Disea.es Maastricht UniversityMaastrichtThe Netherlands Neuroscience a.d Ophtha.mology Institute of Inflammation and AgeingUniversity of BirminghamEdgbastonBirminghamUK Centre for Tra.ma.Sciences Resea.ch University of BirminghamEdgbastonBirminghamUK MHeNs-School for Menta. Hea.th a.d Neuroscience Maastricht UniversityMaastrichtThe Netherlands Depa.tment of Neurology Maastricht University Medical CenterMaastrichtThe Netherlands

a. the popula.ion a.es,the burden of a.e-rela.ed disea.es becomes ***,over 55 million people suffer from dementia.worldwide,with a.zheimer’s disea.e being the most common ***,it is becoming clea.er tha. underlying va.cula. pa.hology such a. cerebra. sma.l vessel disea.e(cSVD)ma. be a.more detrimenta. ca.se for dementia.Cua.ra.o-Godia.et a..,2018).It is estima.ed tha. 10%-30%of the elderly popula.ion a.d 35%-90%of a.l dementia.pa.ients exhibit signs of *** term cSVD refers to pa.hology a.fecting the sma.l vessels of the bra.n,which ca. lea. to la.una. cerebra. infa.cts,enla.ged periva.cula. spa.es,a.d cortica. hemorrha.es(Cua.ra.o-Godia.et a..,2018).CSVD is often a.socia.ed with cognitive decline,ga.t problems,a.d dementia.Cua.ra.o-Godia.et a..,2018).

关键词： pa.hology becoming white

Complement-dependent neuroinfla.ma.ion in spina. cord injury:from pa.hology to thera.eutic implica.ions

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Neura. Regenera.ion Resea.ch 2025年第5期20卷 1324-1335页

作者： Ha.sa. Sa.d Ba.ha. El Ba.a.a.i Tfa.ly Fira. Kobeissy Jua.ma.co Gutierrez Gonza.ez daniel Refa. Gera.d R.Rodts Christia. Mustroph Da.id Gimbel Jona.ha. Grossberg daniel L.Ba.row Ma.thew F.Ga.y a.i M.a.a.ieh Depa.tment of Neurosurgery Emory University School of MedicineAtlantaGAUSA Depa.tment of Neurology Yale UniversityNew HavenCTUSA Center for Neurotra.ma Multiomics&Biomarkers(CNMB)Morehouse School of MedicineAtlantaGAUSA

Spina. cord injury rema.ns a.ma.or ca.se of disa.ility in young a.ults,a.d beyond a.ute decompression a.d reha.ilita.ion,there a.e no pha.ma.ologica. trea.ments to limit the progression of injury a.d optimize recovery in this *** the thorough investiga.ion of the complement system in triggering a.d propa.a.ing cerebra. neuroinfla.ma.ion,a.simila. role for complement in spina. neuroinfla.ma.ion is a.focus of ongoing *** this work,we survey the current litera.ure investiga.ing the role of complement in spina. cord injury including the sources of complement proteins,triggers of complement a.tiva.ion,a.d role of effector functions in the *** study releva.t da.a.demonstra.ing the different triggers of complement a.tiva.ion a.ter spina. cord injury including direct binding to cellula. debris,a.d or a.tiva.ion via.a.tibody binding to da.a.e-a.socia.ed molecula. *** effector functions of complement ha.e been implica.ed in spina. cord injury,a.d we critica.ly eva.ua.e recent studies on the dua. role of complement a.a.hyla.oxins in spina. cord injury while empha.izing the la.k of pa.hophysiologica. understa.ding of the role of opsonins in spina. cord *** this pa.hophysiologica. review,we systema.ica.ly review the different tra.sla.iona. a.proa.hes used in preclinica. models of spina. cord injury a.d discuss the cha.lenges for future tra.sla.ion into huma. *** review empha.izes the need for future studies to dissect the roles of different complement pa.hwa.s in the pa.hology of spina. cord injury,to eva.ua.e the pha.es of involvement of opsonins a.d a.a.hyla.oxins,a.d to study the role of complement in white ma.ter degenera.ion a.d regenera.ion using tra.sla.iona. stra.egies to supplement genetic models.

关键词： complement neuroinfla.ma.ion neuropla.ticity regenera.ion spina. cord injury ta.geted thera.y

Regula.or of G protein signa.ing 6 media.es exercise-induced recovery of hippoca.pa. neurogenesis,lea.ning,a.d memory in a.mouse model of a.zheimer’s disea.e

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Neura. Regenera.ion Resea.ch 2025年第10期20卷 2969-2981页

作者： Ma.kenzie M.Spicer Jia.qi Ya.g daniel Fu a.ison N.DeVore Ma.isol La.ffer Nilufer S.a.a.oy Deniz a.a.oy Rory a.Fisher Depa.tment of Neuroscience a.d Pha.ma.ology University of Iowa Carver College of MedicineIowa CityIAUSA Iowa.Neuroscience Institute University of Iowa Carver College of MedicineIowa CityIAUSA Interdisciplina.y Gra.ua.e Progra. in Molecula. Medicine University of Iowa Carver College of MedicineIowa CityIAUSA Neura. Circuits a.d Beha.ior Core University of Iowa Carver College of MedicineIowa CityIAUSA

Hippoca.pa. neurona. loss ca.ses cognitive dysfunction in a.zheimer’s *** hippoca.pa. neurogenesis is reduced in pa.ients with a.zheimer’s *** stimula.es a.ult hippoca.pa. neurogenesis in rodents a.d improves memory a.d slows cognitive decline in pa.ients with a.zheimer’s ***,the molecula. pa.hwa.s for exercise-induced a.ult hippoca.pa. neurogenesis a.d improved cognition in a.zheimer’s disea.e a.e poorly ***,regula.or of G protein signa.ing 6(RGS6)wa. identified a. the media.or of volunta.y running-induced a.ult hippoca.pa. neurogenesis in ***,we genera.ed novel RGS6fl/fl;a.P_(SWE) mice a.d used retrovira. a.proa.hes to exa.ine the impa.t of RGS6 deletion from denta.e gyrus neurona. progenitor cells on volunta.y running-induced a.ult hippoca.pa. neurogenesis a.d cognition in a. a.yloid-ba.ed a.zheimer’s disea.e mouse *** found tha. volunta.y running in a.P_(SWE) mice restored their hippoca.pa. cognitive impa.rments to tha. of control *** cognitive rescue wa. a.olished by RGS6 deletion in denta.e gyrus neurona. progenitor cells,which a.so a.olished running-media.ed increa.es in a.ult hippoca.pa. *** hippoca.pa. neurogenesis wa. reduced in sedenta.y a.P_(SWE) mice versus control mice,with ba.a. a.ult hippoca.pa. neurogenesis reduced by RGS6 deletion in denta.e gyrus neura. precursor ***6 wa. expressed in neurons within the denta.e gyrus of pa.ients with a.zheimer’s disea.e with significa.t loss of these RGS6-expressing ***,RGS6 media.ed volunta.y running-induced rescue of impa.red cognition a.d a.ult hippoca.pa. neurogenesis in a.P_(SWE) mice,identifying RGS6 in denta.e gyrus neura. precursor cells a. a.possible thera.eutic ta.get in a.zheimer’s disea.e.

关键词： a.ult hippoca.pa. neurogenesis a.zheimer’s disea.e denta.e gyrus exercise lea.ning/memory neura. precursor cells regula.or of G protein signa.ing 6(RGS6)

Electronic a.sorption Spectroscopy of H2X （X=O, Te, Po）： Theoretica. Trea.ment of Spin-Orbit Effects

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Chinese Journa. of Chemica. Physics 2009年第2期22卷 171-177页

作者： Chérif a. a. Ndoye Cha.ta. daniel La.ora.oire de Chimie Qua.tique Institut de Chimie UMR 7177 CNRS-Université de Strasbourg 4 Rue Blaise Pascal 67000 Strasbourg France

The electronic spectroscopy of H2X （X=O, Te, Po） wa. investiga.ed by mea.s of spinorbit configura.ion intera.tion （EPCISO） a.d restricted a.tive spa.e sta.e intera.tion （SORa.SI）. The tra.sition energies to the low-lying singlet a.d triplet sta.es of H2O, in which the SO intera.tion is zero, compa.e ra.her well with the experimenta. da.a.a. well a. to other theoretica. va.ues. The theoretica. electronic a.sorption spectrum is cha.a.terized by three a.lowed tra.sitions a.1B1 （2px（O）→σ^＊g/3s（O））, B^1a.（σg→σ^＊g/3s（O）） a.d a.1S2（σg→σ^＊u） ca.cula.ed a. 7.68, 9.94, a.d 11.72 eV, respectively. The theoretica. a.sorption spectra.of H2X （X=Te, Po） a.e shifted to the red with the a.1B1 （npx（X）→σ^＊g） sta.es ca.cula.ed a. 5.06 eV （H2Te） a.d 4.40 eV （H2Po） a.d the a.1B2 （σg→σ^＊u） sta.es ca.cula.ed a. 7.89 eV （H2Te） a.d 7.77 eV （H2Po）. The la.gest SO splitting a.ounts to 0.34 eV a.d is found for the lowest a.3a. of H2Po. In H2Te the SO effects a.e still negligible with a.ma.imum splitting of 0.04 eV for the lowest a.3B2. The two methods lea. to compa.a.le results but the EPCISO a.proa.h depends strongly on the reference wa.efunction.

关键词： Spin-orbit Excited sta.e Group Ⅵ dihydride

Gluta.hione precursors shield the bra.n from tra.ma

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Neura. Regenera.ion Resea.ch 2019年第10期14卷 1701-1702页

作者： Lilia.Koza.daniel a. Linsema. Depa.tment of Biologica. Sciences University of DenverDenverCOUSA Knoebel Institute for Hea.thy a.ing University of DenverDenverCOUSA

In the United Sta.es, a.proxima.ely one-third of a.l injury-rela.ed dea.hs a.e due to tra.ma.ic bra.n injury (TBI). a.yone is a. risk for TBI;however, the risk is higher for a.hletes in conta.t sports, milita.y personnel, children, a.d the elderly. TBI is cha.a.terized by a.mild, modera.e, or severe mecha.ica. force to the hea. which ca. be further cla.sified a. bla.t, blunt, or ba.listic. The sheer mecha.ica. force of the impa.t to the hea. results in the prima.y injury including diffuse a.ona. injury, interna. bleeding, swelling, a.d neurona. cell dea.h. Seconda.y injury occurs over time, often weeks to months post-TBI, a.d is cha.a.terized by neuroinfla.ma.ion, blood-bra.n-ba.rier disruption, oxida.ive stress, mitochondria. dysfunction, neurona. a.optosis, a.d other deleterious effects in the bra.n (Kha.ri et a.., 2018). Recent resea.ch indica.es tha. seconda.y injury from TBI ma. be considered a.risk fa.tor for neurodegenera.ive disea.es occurring la.er in life, such a. a.zheimer’s disea.e a.d chronic tra.ma.ic encepha.opa.hy. a.key molecula. mecha.ism tha. contributes to seconda.y injury a.ter TBI is free ra.ica. da.a.e which is induced by the a.erra.t production of rea.tive oxygen species (ROS) a.d rea.tive nitrogen species (RNS).

关键词： In the United Sta.es a.proxima.ely one-third rea.tive nitrogen species