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壳聚糖抗菌成膜喷剂在鼻咽癌患者PICC所致接触性皮炎治疗中的应用效果

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武警医学 2024年第2期35卷 125-129页

作者：罗晓华郑艺君王丽红林丹凤张红梅刘志慧联勤保障部队第909医院/厦门大学附属东南医院肿瘤科漳州363000 联勤保障部队第909医院/厦门大学附属东南医院护理部漳州363000

目的探讨壳聚糖抗菌成膜喷剂在鼻咽癌患者经外周静脉置入中心静脉导管(PICC)置管部位接触性皮炎治疗中的应用效果。方法选取2020-05至2022-04联勤保障部队第909医院因置入PICC所致接触性皮炎的94例鼻咽癌患者为研究对象,其中2020-05至20... 详细信息

目的探讨壳聚糖抗菌成膜喷剂在鼻咽癌患者经外周静脉置入中心静脉导管(PICC)置管部位接触性皮炎治疗中的应用效果。方法选取2020-05至2022-04联勤保障部队第909医院因置入PICC所致接触性皮炎的94例鼻咽癌患者为研究对象,其中2020-05至2021-04的46例患者为对照组,2021-05至2022-04的48例患者为观察组。对照组采用地塞米松注射液外涂联合3M透明敷料行PICC换药,观察组采用喷涂壳聚糖抗菌成膜喷剂联合3M透明敷料行PICC换药。对比观察两组患者临床疗效、并发症的发生率、愈合时间、换药次数、患者的自付费用及满意度情况。结果观察组治疗第1周、第2周总有效率(95.83%,100%)均显著高于对照组治疗总有效率(73.91%,89.13%)(P0.05)。结论壳聚糖抗菌成膜喷剂治疗鼻咽癌同步放化疗患者PICC置管部位接触性皮炎效果明显,可减少换药次数,减轻护理工作量,降低局部感染率,提高患者满意度。

关键词：壳聚糖抗菌成膜喷剂经外周静脉置入中心静脉导管接触性皮炎治疗效果

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微分控制模型下的精量播种机智能应用

农机化研究 2022年第8期44卷 187-192页

作者：林丹凤山东交通职业学院山东潍坊261206

为进一步提高我国农作物播种效率,从提升精量播种机实践应用角度出发,融合数学微分控制理论,针对整机的硬件构成与软件控制展开优化研究。以影响实现精量播种的关键影响因素为出发点,依据播种智能作业控制流程,建立以跟踪、扰动、补偿... 详细信息

为进一步提高我国农作物播种效率,从提升精量播种机实践应用角度出发,融合数学微分控制理论,针对整机的硬件构成与软件控制展开优化研究。以影响实现精量播种的关键影响因素为出发点,依据播种智能作业控制流程,建立以跟踪、扰动、补偿为主线的微分控制模型,并给予执行硬件配置与软件程序导入,搭建播种精量控制系统进行作业试验。结果表明:在一定墒情土壤条件下,经微分控制理论应用后,整机的精播准确率与精播效率分别提升了10.18%和9.41%,播深控制合格率与播种穴距合格率均保持在90%以上,满足我国相关农机装备的设计要求。研究从本质上思考优化农机装备控制的制约因素,以数学微分控制模型为设计核心,对于我国农机装备智能优化具有很好的启发作用。

关键词：精量播种机微分控制精播准确率硬件配置

DNA methylation in poultry:a review

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Journal of Animal Science and Biotechnology 2024年第2期15卷 509-518页

作者： Xing Ju Zhijun Wang danfeng Cai Semiu Folaniyi Bello Qinghua Nie State Key Laboratory for Conservation and Utilization of Subtropical Agro‑Bioresources Lingnan Guangdong Laboratory of AgricultureCollege of Animal ScienceSouth China Agricultural UniversityGuangzhouGuangdong 510642China Guangdong Provincial Key Lab of Agro‑Animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics Breeding and ReproductionMinistry of AgricultureGuangzhouGuangdong 510642China College of Animal Science and Technology Zhejiang Agriculture and Forestry University666 Wusu RoadLin’an 311300China

As an important epigenetic modification,DNA methylation is involved in many biological processes such as animal cell differentiation,embryonic development,genomic imprinting and sex chromosome *** DNA methylation sequencing becomes more sophisticated,it becomes possible to use it to solve more zoological *** paper reviews the characteristics of DNA methylation,with emphasis on the research and application of DNA methylation in poultry.

关键词： CpG islands Differentially methylated genes Differentially methylated regions DNA methylation Poultry

The proximity between hydroxyl and single atom determines the catalytic reactivity of Rh1/CeO_(2) single-atom catalysts

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Nano Research 2024年第1期17卷 397-406页

作者： danfeng Wu Shuyun Zhou Congcong Du Juan Li Jianyu Huang Hong-xia Shen Abhaya K.Datye Shan Jiang Jeffrey T.Miller Sen lin Haifeng Xiong State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China State Key Laboratory of Photocatalysis on Energy and Environment College of ChemistryFuzhou UniversityFuzhou 350002China Clean Nano Energy Center State Key Laboratory of Metastable Materials Science and TechnologyYanshan UniversityQinhuangdao 066004China College of Biology and Chemical Engineering Jiaxing UniversityJiaxing 314000China Department of Chemical&Biological Engineering University of New MexicoAlbuquerqueNM 8731-0001USA Davidson School of Chemical Engineering Purdue UniversityWest LafayetteIN 47907-2100USA Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(IKKEM) Xiamen 361102China Fujian Key Laboratory of Rare-earth Functional Materials Fujian Shanhai Collaborative Innovation Center of Rare-earth Functional MaterialsLongyan 366300China

The local structure of the metal single-atom site is closely related to the catalytic activity of metal single-atom catalysts(SACs).However,constructing SACs with homogeneous metal active sites is a challenge due to the surface heterogeneity of the conventional ***,we prepared two Rh1/CeO_(2)SACs(0.5Rh1/r-CeO_(2)and 0.5Rh1/c-CeO_(2),respectively)using two shaped CeO_(2)(rod and cube)exposing different facets,i.e.,CeO_(2)(111)and CeO_(2)(100).In CO oxidation reaction,the T100 of 0.5Rh1/r-CeO_(2)SACs is 120°C,while the T100 of 0.5Rh1/c-CeO_(2)SACs is as high as 200°*** in-situ CO diffuse reflectance infrared Fourier transform spectroscopy(CO-DRIFTS),we found that the proximity between OH group and Rh single atom on the plane surface plays an important role in the catalytic activity of Rh1/CeO_(2)SAC system in CO *** Rh single atom trapped at the CeO_(2)(111)crystal surface forms the Rh1(OH)adjacent species,which is not found on the CeO_(2)(100)crystal surface at room ***,during CO oxidation,the OH group far from Rh single atom on the 0.5Rh1/c-CeO_(2)disappears and forms Rh1(OH)adjacent species when the temperature is above 150°*** formation of Rh1(OH)adjacentCO intermediate in the reaction is pivotal for the excellent catalytic activity,which explains the difference in the catalytic activity of Rh single atoms on two different CeO_(2)*** formed Rh1(OH)adjacent-O-Ce structure exhibits good stability in the reducing atmosphere,maintaining the Rh atomic dispersion after CO oxidation even when pre-reduced at high temperature of 500°*** functional theory(DFT)calculations validate the unique activity and reaction path of the intermediate Rh1(OH)adjacentCO species *** work demonstrates that the proximity between metal single atom and hydroxyl can determine the formation of active intermediates to affect the catalytic performances in catalysis.

关键词： crystal plane Rh1/CeO_(2)single-atom catalyst proximity of Rh and hydroxyl coordination structure CO oxidation

The dusty and extremely red progenitor of the typeⅡsupernova 2023ixf in Messier 101

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Science China(Physics,Mechanics & Astronomy) 2024年第1期67卷 160-172页

作者： danfeng Xiang Jun Mo lingzhi Wang Xiaofeng Wang Jujia Zhang Han lin Lifan Wang Department of Physics Tsinghua UniversityBeijing 100084China South America Center for Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China Beijing Planetarium Beijing Academy of Sciences and TechnologyBeijing 100044China Yunnan Observatories Chinese Academy of SciencesKunming 650216China Key Laboratory for the Structure and Evolution of Celestial Objects Chinese Academy of SciencesKunming 650216China International Centre of Supernovae Yunnan Key LaboratoryKunming 650216China Mitchell Institute for Fundamental Physics and Astronomy Texas A&M UniversityCollege StationTX 77843USA

Stars with initial masses in the range of 8-25 solar masses are thought to end their lives as hydrogen-rich supernovae(SNeⅡ).Based on the pre-explosion images of Hubble space telescope(HST)and Spitzer space telescope,we place tight constraints on the progenitor candidate of type IIP SN 2023ixf in Messier *** of the spectral energy distribution(SED)of its progenitor with dusty stellar spectral models results in an estimation of the effective temperature as 3091+*** luminosity is estimated as lg(L/L⊙)~4.83,consistent with a red supergiant(RSG)star with an initial mass of 12-1+2M⊙.The derived mass loss rate(6×10^(-6)-9×10^(-6)M⊙yr^(-1))is much lower than that inferred from the flash spectroscopy of the SN,suggesting that the progenitor experienced a sudden increase in mass loss when approaching the final *** the infrared bands,significant deviation from the range of regular RSGs in the color-magnitude diagram and period-luminosity space of the progenitor star indicates enhanced mass loss and dust *** with new evidence of polarization at the early phases of SN 2023ixf,such a violent mass loss is likely a result of binary interaction.

关键词： stellar evolution mass loss red supergiants infrared emission supernovae

Circulating tumor cells:biology and clinical significance

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Signal Transduction and Targeted Therapy 2021年第12期6卷 3510-3533页

作者： danfeng lin Lesang Shen Meng Luo Kun Zhang Jinfan Li Qi Yang Fangfang Zhu Dan Zhou Shu Zheng Yiding Chen Jiaojiao Zhou Department of Breast Surgery the Second Affiliated HospitalZhejiang University School of MedicineHangzhouChina Cancer Institute(Key Laboratory of Cancer Prevention and Intervention China National Ministry of Education)the Second Affiliated HospitalZhejiang University School of MedicineHangzhouChina Department of Breast Surgery the First Affiliated Hospital of Wenzhou Medical UniversityWenzhouChina Department of Pathology the Second Affiliated HospitalZhejiang University School of MedicineHangzhouChina Department of Surgery Traditional Chinese Medical Hospital of ZhujiShaoxingChina

Circulating tumor cells(CTCs)are tumor cells that have sloughed off the primary tumor and extravasate into and circulate in the *** of the metastatic cascade of CTCs has tremendous potential for the identification of targets against cancer *** these very rare CTCs among the massive blood cells is ***,emerging technologies for CTCs detection have profoundly contributed to deepening investigation into the biology of CTCs and have facilitated their clinical *** technologies for the detection of CTCs are summarized herein,together with their advantages and *** detection of CTCs is usually dependent on molecular markers,with the epithelial cell adhesion molecule being the most widely used,although molecular markers vary between different types of *** associated with epithelial-tomesenchymal transition and stemness have been identified in CTCs,indicating their increased metastatic *** a small proportion of CTCs can survive and eventually initiate metastases,suggesting that an interaction and modulation between CTCs and the hostile blood microenvironment is essential for CTC ***-cell sequencing of CTCs has been extensively investigated,and has enabled researchers to reveal the genome and transcriptome of ***,we also review the clinical applications of CTCs,especially for monitoring response to cancer treatment and in evaluating ***,CTCs have and will continue to contribute to providing significant insights into metastatic processes and will open new avenues for useful clinical applications.

关键词： clinical eventually deepening

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漳州市南江滨路景观绿化设计

南方农业 2023年第22期17卷 194-197页

作者：林丹凤上海市政工程设计研究总院(集团)有限公司厦门分公司福建厦门361000

在我国大力推广生态文明理念的背景下,城市道路景观需要融合城市文化底蕴,结合可持续发展,合理设计道路景观内容,充分彰显作用及优势。为营造良好的城市景观,提升城市居民幸福感,以福建省漳州市南江滨路景观绿化设计为例,结合地域文化... 详细信息

在我国大力推广生态文明理念的背景下,城市道路景观需要融合城市文化底蕴,结合可持续发展,合理设计道路景观内容,充分彰显作用及优势。为营造良好的城市景观,提升城市居民幸福感,以福建省漳州市南江滨路景观绿化设计为例,结合地域文化及生态环境,介绍了适应当地生态条件、以林荫绿化为主导、可持续发展等市政道路景观绿化设计的原则,同时从工程概况、上位规划、总体设计、分区设计、景观节点打造等方面探讨了南江滨路景观绿化设计方案。

关键词：市政道路景观设计福建省漳州市

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实验室危险化学品管理的经验

实验室科学 2022年第3期25卷 210-212页

作者：林丹枫赵东岳福建师范大学福建省发育与神经生物学重点实验室生命科学学院福建福州350108

高校实验室安全是校园安全文化建设的重点之一,而危险化学品规范化管理是实验室安全工作中的要点。目前,针对高校实验室危险化学品存在安全隐患复杂、突发性强的特点并结合福建师范大学实际情况,实施了“惩”与“防”结合的管理模式,采... 详细信息

高校实验室安全是校园安全文化建设的重点之一,而危险化学品规范化管理是实验室安全工作中的要点。目前,针对高校实验室危险化学品存在安全隐患复杂、突发性强的特点并结合福建师范大学实际情况,实施了“惩”与“防”结合的管理模式,采取“正向引导”和“逆向阻止”的措施,来提升实验室危险化学品的管理水平,为校园安全稳定提供基本保障。

关键词：实验室安全危险化学品管理校园安全

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实验动物屏障设施的灾难评估及灾后紧急处理

实验室科学 2022年第6期25卷 214-216页

作者：赵东岳林丹枫福建师范大学生命科学学院福建福州350108

目前大部分实验动物的封闭式设施都采用了集中通风、供暖/制冷模式,确保环境变化被控制在一个稳定的范围内。这不仅有利于维护动物的健康,也可以减少实验变量,最大程度上满足动物实验的可重复性。然而,封闭式环境出现异常情况,可能导致... 详细信息

目前大部分实验动物的封闭式设施都采用了集中通风、供暖/制冷模式,确保环境变化被控制在一个稳定的范围内。这不仅有利于维护动物的健康,也可以减少实验变量,最大程度上满足动物实验的可重复性。然而,封闭式环境出现异常情况,可能导致整个种群灾难性的后果。因此,从实验动物福利角度看,设施管理的关键是保证设施的条件符合动物的生理和心理的需求,同时需要提前制定相关的对策来应对可能发生的灾难或者一系列后果,确保动物设施持续安全运行。

关键词：实验动物屏障设施灾难评估紧急处理