检索结果-南通市图书馆

An electropenetrography waveform library for the probing and ingestion behaviors of Culex tarsalis on human hands

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect science 2024年第4期31卷 1165-1186页

作者： Anastasia m.W.Cooper Samuel B.Jameson Victoria Pickens Cameron Osborne Elaine A.Backus Kristopher Silver dana N.mitzel Department of Entomology Kansas State UniversityManhattanKansasUSA Department of Tropical medicine Tulane University School of Public Health and Tropical MedicineNew OrleansLos AngelesUSA USDA Agricultural Research Service San Joaquin Valley Agricultural Sciences CenterParlierCaliforniaUSA National Bio and Agro-Defense Facility USDA Agricultural Research ServiceManhattanKansasUSA

Culex tarsalis Coquillett(Diptera:Culicidae)mosquitoes are capable of vectoring numerous pathogens affecting public and animal ***,the probing behaviors of mosquitoes are poorly understood because they occur in opaque ***(EPG)has the potential to elucidate these behaviors by recording the electrical signals generated during *** used an AC–DC EPG with variable input resistors(Ri levels)to construct a waveform library for *** feeding on human *** events associated with mosquito probing were used to characterize waveforms at four Ri levels and with two electrical current *** optimal settings for EPG recordings of *** probing on human hands was an Ri level of 10^(7)Ohms using an applied signal of 150 millivolts alternating *** for *** included those previously observed and associated with probing behaviors in Aedes aegypti L.(Diptera:Culicidae):waveform families J(surface salivation),K(stylet penetration through the skin),L(types 1 and 2,search for a blood vessel/ingestion site),m(types 1 and 2,ingestion),N(type 1,an unknown behavior which may be a resting and digestion phase),and W(withdrawal).However,we also observed variations in the waveforms not described in ***,which we named types L3,m3,m4,and *** investigation enhances our understanding of mosquito probing *** also provides a new tool for the automated calculation of peak *** work will facilitate future pathogen acquisition and transmission studies and help identify new pest and disease management targets.

关键词： AC-DC blood feeders electrical penetration graph EPG human hands mosquitoes waveform library

Association of initial assessment variables and mortality in severe pediatric traumatic brain injury

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediatric Surgery 2024年第2期7卷 125-133页

作者： Katherine C Bergus Kelli N Patterson Lindsey Asti Josh Bricker Tariku J Beyene Lauren N schulz dana m sc.wartz Rajan K Thakkar Eric A Sribnick Pediatric Surgery Nationwide Children's HospitalColumbusOhioUSA CenterforSurgical Outcomes Research Nationwide Children's HospitalColumbusOhioUSA Neurologic Surgery The Ohio State UniversityColumbusOhioUSA Neurologic Surgery Nationwide Children's HospitalColumbusOhioUSA

Background Predictive scales have been used to prognosticate long-term outcomes of traumatic brain injury(TBI),but gaps remain in predicting mortality using initial trauma resuscitation *** sought to evaluate the association of clinical variables collected during the initial resuscitation of intubated pediatric severe patients with TBI with in-hospital *** Intubated pediatric trauma patientsma scale(GCS)score≤8)from January 2011 to December 2020 were *** between initial trauma resuscitation variables(temperature,pulse,mean arterial blood pressure,GCS score,hemoglobin,international normalized ratio(INR),platelet count,oxygen saturation,end tidal carbon dioxide,blood glucose and pupillary response)and mortality were evaluated with multivariable logistic *** Among 314 patients,median age was 5.5 years(interquartile range(IQR):2.2-12.8),GCS score was 3(IQR:3-6),Head Abbreviated Injury score(hAIS)was 4(IQR:3-5),and most had a severe(25-49)Injury Severity score(ISS)(48.7%,153/314).Overall mortality was 26.8%.GCS score,hAIS,ISS,INR,platelet count,and blood glucose were associated with in-hospital mortality(all pscore increased,the odds of mortality *** 1-point increase in GCS score was associated with a 35%decrease in odds of *** hAIS,INR,and blood glucose increased,the odds of mortality *** each 1.0 unit increase in INR,the odds of mortality increased by 1427%.Conclusions Pediatric patients with severe TBI are at substantial risk for in-hospital *** are needed to examine whether earlier interventions targeting specific parameters of INR and blood glucose impact mortality.

关键词： mortality pediatric traumatic

护理专业国际学生短期访学教育项目的设计与实施

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Nursing sciences 2024年第1期11卷 83-90页

作者： Ubolrat Piamjariyakul Saima Shafique dana L.Friend Kimberly A.Adams Wiyakarn Sanghuachang Trisha m.Petitte Stephanie Young school of Nursing West Virginia UniversityMorgantownWVUSA Boromarajonani College of Nursing Saraburi SaraburiThailand

目的旨在描述制定及评估一项短期留学生研究和教育项目。方法研究分为项目制定与实施及评价2部分。根据1名国际学生的短期访学需求,护理学院的全球护理项目协调员和首席导师共同确定项目基本内容和团队成员。该项目学习活动考虑了该国... 详细信息

目的旨在描述制定及评估一项短期留学生研究和教育项目。方法研究分为项目制定与实施及评价2部分。根据1名国际学生的短期访学需求,护理学院的全球护理项目协调员和首席导师共同确定项目基本内容和团队成员。该项目学习活动考虑了该国际学生对老年人和居家临终关怀的兴趣,包括4项内容:.开展研究工作,参与教学活动,参与临床实践活动,以及特殊活动和专业发展培训课程。在为期6个月的访学结束时,对参与此次教学活动的教师、研究生及留学生进行访谈和简短问卷调查。结果通过访谈了解到3个方面的内容:通过参与该项目中获得的经验(增强了教育和研究的多样性,获得了新的全球医疗保健知识,对文化意识的自我反思和促进);项目实施的障碍和挑战(签证申请过程,英语语言障碍,缺乏公共交通设施,时间安排冲突);克服这些障碍和挑战的策略(在课程中增加文化多样性信息;与其他同学一起学习英语;使用不同的沟通技巧;在签证申请过程中与大学全球事务办公室持续合作;提供互动体验)。所有项目参与者都对该项目表示非常满意(4.67±0.50),认为对他们在科研、教学和临床实践方面的护理技能有很大影响(4.67±0.50)。结论此次项目的参与者均获得了相关经验,可用于今后的教学指导活动。国际护理专业学生需要得到帮助才能更好地适应访学环境,教师必须具有文化敏感性,了解学生的学习需求,并倡导营造适合学生学习的环境。

关键词：评价国际学生护理教育课程

纤维弯曲对其集合体过滤特性影响的稳态数值分析

在线全文

学校读者我要写书评

暂无评论

纺织学报 2024年第7期45卷 31-39页

作者：刘倩倩尤健明王琰孙成磊 JIRI militky dana Kremenakova JAKUB Wiener 祝国成浙江理工大学纺织科学与工程学院(国际丝绸学院) 浙江杭州310018 浙江朝晖过滤技术股份有限公司浙江嘉兴314511 浙江理工大学浙江-捷克先进纤维材料联合实验室浙江杭州310018 利贝雷茨理工大学纺织工程学院捷克利贝雷茨46117 浙江省现代纺织技术创新中心(鉴湖实验室) 浙江绍兴312000

为探究纤维过滤介质中纤维曲率对其内部速度分布、压力损失、过滤效率的影响,通过Digimat建模软件建立曲率K分别为0、2、4、6,固体体积分数为8%,在三维空间中随机分散排列的纤维过滤介质模型,结合计算流体力学方法,基于拉格朗日离散模型... 详细信息

为探究纤维过滤介质中纤维曲率对其内部速度分布、压力损失、过滤效率的影响,通过Digimat建模软件建立曲率K分别为0、2、4、6,固体体积分数为8%,在三维空间中随机分散排列的纤维过滤介质模型,结合计算流体力学方法,基于拉格朗日离散模型和Laminar流场,利用雷诺相似准则,设置入口速度分别为0.05、0.142、0.5、1、2 m/s,平均颗粒粒径为0.25、0.5、1、1.5、2.5、4、5 mm,对微米纤维模型内部气-固两相流动情况进行数值模拟。结果表明:随着纤维曲率K由0增大至6,在入口速度为0.5 m/s时,纤维曲率对速度场分布的影响不明显,速度场的分布呈无规律性;纤维曲率对模型内部压力损失有显著影响,随着纤维曲率的提高,纤维模型内部压力损失呈线性增大;纤维过滤介质的过滤效率随纤维模型曲率的增大而提高,在入口速度为1 m/s、模型曲率K为6时,对平均粒径为5 mm的颗粒过滤效率接近90%,明显高于相同粒径下K为0时的过滤效率。

关键词：计算流体力学纤维曲率压力损失数值模拟过滤效率

在线全文

学校读者我要写书评

暂无评论

预防舞弊金字塔

新理财（公司理财） 2024年第6期 77-80页

作者： Douglas m.Boyle dana R.Hermanson 不详

财会人员可基于一种新模型来培养防范舞弊的能力。美国注册舞弊审查师协会(ACFE)两年一次的调查显示,舞弊仍是一个重大的社会问题,全球每年因舞导致的损失高达数万亿美元。不幸的是,财会人员往往会屈服于压力或不当激励措施而实施舞弊,... 详细信息

财会人员可基于一种新模型来培养防范舞弊的能力。美国注册舞弊审查师协会(ACFE)两年一次的调查显示,舞弊仍是一个重大的社会问题,全球每年因舞导致的损失高达数万亿美元。不幸的是,财会人员往往会屈服于压力或不当激励措施而实施舞弊,这使得他们成为ACFE调查中职业舞弊案的主要实施者之一。

关键词：财会人员舞弊案防范舞弊金字塔主要实施者不当激励预防舞弊 ACF

黏性颗粒在不同截面形状纤维表面沉积特性的数值模拟

在线全文

学校读者我要写书评

暂无评论

现代纺织技术 2024年第6期32卷 41-51页

作者：刘倩倩尤健明王琰孙成磊 JIRI militky dana Kremenakova 姚菊明祝国成浙江理工大学纺织科学与工程学院(国际丝绸学院) 杭州310018 浙江理工大学浙江-捷克先进纤维材料联合实验室杭州310018 浙江朝晖过滤技术股份有限公司浙江嘉兴314511 利贝雷茨理工大学纺织工程学院捷克利贝雷茨46117 现代纺织技术创新中心(鉴湖实验室) 浙江绍兴312000

为了探究黏性颗粒在不同截面形状纤维表面的沉积特性,选择截面为圆形、三角形和十字形的纤维作为研究对象,通过Digimat、Solidworks建模软件构建在空间中呈随机分布的刚性三维纤维体模型;利用计算流体力学和离散单元法耦合的方法,基于la... 详细信息

为了探究黏性颗粒在不同截面形状纤维表面的沉积特性,选择截面为圆形、三角形和十字形的纤维作为研究对象,通过Digimat、Solidworks建模软件构建在空间中呈随机分布的刚性三维纤维体模型;利用计算流体力学和离散单元法耦合的方法,基于laminar流场特征,引入JKR(Johnson-kendall-roberts)接触模型,对黏性颗粒在不同纤维表面的沉积特性进行气-固两相耦合数值模拟。模拟结果表明:在黏性颗粒的运动过程中,过滤机理会随时间而变化。初期,捕集主要依赖纤维表面的吸附作用,而后期主要通过纤维本身和颗粒之间的黏附团聚运动共同实现,形成了“尘滤尘”现象。此外,颗粒间滚动摩擦系数对颗粒在纤维上沉积的影响很大。滚动摩擦系数越大,颗粒之间的接触力链结构越稳定,颗粒更难脱落。在3种截面形状的纤维中,十字形截面的捕集效率最高,三角形次之,圆形最低。该研究探究了黏性颗粒与纤维之间的相互作用,优化了纤维结构和布局,为提高空气过滤材料的过滤效率提供了设计思路和理论参考。

关键词：气-固两相流纤维表面黏性颗粒滚动摩擦系数颗粒捕集

mining diversity of the natural biorefinery housed within Tipula abdominalis larvae for use in an industrial biorefinery for production of lignocellulosic ethanol

在线全文

学校读者我要写书评

暂无评论

Insect science 2010年第3期17卷 303-312页

作者： dana m. Cook Joy Doran-Peterson microbiology Department University of Georgia Athens Georgia USA

Although they are the largest taxonomic group of animals, relatively few insects have been examined for symbiotic relationships with micro-organisms. However, this is rapidly changing because of the potential for examination of the natural insectmicrobe-lignocellulose interactions to provide insights for biofuel technology. micro-organisms associated with lignocellulose-consuming insects often facilitate the digestion of the recalcitrant plant diet; therefore these microbial communities may be mined for novel lignocellulose-degrading microbes, or for robust and inexpensive biocatalysts necessary for economically feasible biofuel production from lignocellulose. These insect-microbe interactions are influenced by the ecosystem and specific lignocellulose diet, and appre- ciating the whole ecosystem-insect-microbiota-lignocellulose as a natural biorefinery provides a rich and diverse framework from which to design novel industrial processes. One such natural biorefinery, the Tipula abdominalis larvae in riparian ecosystems, is reviewed herein with applications for biochemical processes and overcoming challenges involved in conversion of lignocellulosic biomass to fuel ethanol. From the dense and diverse T. abdominalis larval hindgut microbial community, a cellulolytic bacterial isolate, 27C64, demonstrated enzymatic activity toward many model plant polymers and also produced a bacterial antibiotic. 27C64 was co-cultured with yeast in fermentation of pine to ethanol, which allowed for a 20% reduction of commercial enzyme. In this study, a micro-organism from a lignocellulose-consuming insect was successfully applied for improvement of biomass-to-biofuel technology.

关键词： ethanol hydrolytic enzymes insect-associated microorganisms lignocellulose

CD8+T cell metabolic flexibility elicited by CD28-ARS2 axisdriven alternative splicing of PKm supports antitumor immunity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & molecular Immunology 2024年第3期21卷 260-274页

作者： G.Aaron Holling Colin A.Chavel Anand P.Sharda mackenzie m.Lieberman Caitlin m.James Shivana m.Lightman Jason H.Tong Guanxi Qiao Tiffany R.Emmons Thejaswini Giridharan Shengqi Hou Andrew m.Intlekofer Richard m.Higashi Teresa W.m.Fan Andrew N.Lane Kevin H.Eng Brahm H.Segal Elizabeth A.Repasky Kelvin P.Lee scott H.Olejniczak Department of Immunology Roswell Park Comprehensive Cancer CenterBuffaloNY 14263USA Department of medicine Roswell Park Comprehensive Cancer CenterBuffaloNY 14263USA Human Oncology and Pathogenesis Program Memorial Sloan Kettering Cancer CenterNew YorkNY 10065USA Center for Environmental Systems Biochemistry Department of Toxicology and Cancer Biology and Markey Cancer CenterLexingtonKY 40536USA Department of Cancer Genetics and Genomics Roswell Park Comprehensive Cancer CenterBuffaloNY 14263USA Present address:University of Colorado Boulder BoulderCO 80309USA Present address:dana Farber Cancer Institute BostonMA 02215USA Present address:massachusetts Institute of Technology BostonMA 02139USA Present address:melvin and Bren Simon Comprehensive Cancer Center Indiana University School of MedicineIndianapolisIN 46202USA

metabolic flexibility has emerged as a critical determinant of CD8+T-cell antitumor activity,yet the mechanisms driving the metabolic flexibility of T cells have not been *** this study,we investigated the influence of the nuclear cap-binding complex(CBC)adaptor protein ARS2 on mature T *** doing so,we discovered a novel signaling axis that endows activated CD8+T cells with flexibility of glucose ***2 upregulation driven by CD28 signaling reinforced splicing factor recruitment to pre-mRNAs and affected approximately one-third of T-cell activation-induced alternative splicing *** these effects,the CD28-ARS2 axis suppressed the expression of the m1 isoform of pyruvate kinase in favor of PKm2,a key determinant of CD8+T-cell glucose utilization,interferon gamma production,and antitumor effector ***,PKm alternative splicing occurred independently of CD28-driven PI3K pathway activation,revealing a novel means by which costimulation reprograms glucose metabolism in CD8+T cells.

关键词： Immunometabolism mRNA splicing CD8 T cells ARS2 PKm2

Time Gets more Precise with Transportable Optical Lattice Clocks

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineering 2020年第11期6卷 1210-1211页

作者： dana mackenzie 不详

Of all the units of physical science,one second is perhaps the most *** a meter,we cannot see *** a kilogram,we cannot hold it in our *** a volt,we have no nerves to sense *** a second is the most precisely quantified unit we have[1].This year,metrologists—scientists who study m easurem entannounced the first transportable clock that can measure time to 18 decimal *** put this in perspective,a clock running with this precision since the Big Bang would have lost or gained less than half a second.

关键词： gained Lattice clock