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Pro-fert.lit. effect.of Ficus carica fruit.ext.act.in st.ept.zot.cin-induced male rat.

Asian pacific Journal of Reproduct.on 2024年第1期13卷 34-41页

作者： mat Noor Mahanem Subramaniam Puvarat.esh AbuBakar Umarqayum Shamsusah Nadia A Depart.ent.of Biological Sciences and Biot.chnology Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia43600 BangiSelangorMalaysia inst.t.t. of Biological Sciences Faculty of ScienceUniversity Malaya50603 Kuala LumpurMalaysia Depart.ent.of Eart. Sciences and Environment Faculty of Science and TechnologyUniversiti Kebangsaan MalaysiaBangi 43600Malaysia

Object.ve:t. explore t.e impact.of Ficus carica fruit.aqueous ext.act.on fert.lit. paramet.rs in st.ept.zot.cin(St.)-induced male ***:t.ent.-four male Sprague-Dawley rat. were divided int. four different.*** groups except.a normal cont.ol group were induced wit. 50 mg/kg of st.ept.zot.cin(St.)int.avenously t. induce diabet.s.A posit.ve cont.ol group was t.eat.d wit. an ant.diabet.c drug,met.ormin(500 mg/kg)whereas a negat.ve cont.ol group remained unt.eat.d t.roughout.t.e ***,anot.er diabet.c rat.group received t.eat.ent.wit. 400 mg/kg of aqueous Ficus carica fruit.*** in t.e t.eat.ent.group were administ.red Ficus carica fruit.aqueous ext.act.daily t.rough forcefeeding via oral gavage for a 21-day *** included t.e sperm qualit.(count.mot.lit. and morphology),hist.logy of t.e t.st.s,serum t.st.st.rone and fast.ng blood glucose(FBG)***:t.e FBG level of t.e Ficus carica-t.eat.d rat. exhibit.d a significant.decrease compared t. t.e negat.ve cont.ol group(Pit. analysis also indicat.d t.at.t.e aqueous Ficus carica ext.act.had significant.posit.ve effect. on sperm count.and mot.lit.(Pt.e hist.logy of t.e t.st.s in Ficus caricat.eat.d rat. revealed an improved cell arrangement.in t.e germinal cell ***,serum t.st.st.rone level showed an increment.in t.e Ficus carica t.eat.ent.group in comparison t. t.e negat.ve cont.ol ***:Our findings provide compelling evidence for t.e profert.lit. and ant.-hyperglycemic propert.es of aqueous Ficus carica fruit.ext.act.in diabet.c-induced male rat..

关键词： Ficus carica fruit Male fert.lit. paramet.r Diabet.s mellit.s Ant.-hyperglicemic

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Virt.al t.ansmission Solut.on Based on Bat.ery Energy St.rage Syst.ms t. Boost.t.ansmission Capacit.

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Journal of Modern Power Syst.ms and Clean Energy 2024年第2期12卷 466-474页

作者： matías Agüero Jaime Peralt. Eugenio Quint.na Vict.r Velar Ant.n St.panov Hossein Ashourian Jean Mahseredjian Robert. Cárdenas Coordinador Eléct.ico Nacional SantiagoChile PGSt.ch Montreal Canada Ecole Polyt.chnique de Mont.éal Montréal Canada Universit. of Chile Santiago Chile iEEE

t.e increasing penet.at.on of variable renewable energy(VRE)generat.on along wit. t.e decommissioning of convent.onal power plant. in Chile,has raised several operat.onal challenges in t.e Chilean Nat.onal Power Grid(NPG),including t.ansmission congest.on and VRE *** mit.gat. t.ese limit.t.ons,an innovat.ve virt.al t.ansmission solut.on based on bat.ery energy st.rage syst.ms(BESSs),known as grid boost.r(GB),has been proposed t. increase t.e capacit. of t.e main 500 kV corridor of t.e *** paper analyzes t.e dynamic performance of t.e GB using a wide-area elect.omagnet.c t.ansient.EMt.model of t.e *** GB project.composed of t.o 500 MVA BESS unit. at.each ext.eme of t.e 500 kV corridor,allows increasing t.e t.ansmission capacit. for 15 min during N-1 cont.ngencies,overcoming t.ansmission limit.t.ons under normal operat.on condit.ons while maint.ining syst.m st.bilit. during *** dynamic behavior of t.e GB is also analyzed t. cont.ol power flow as well as volt.ge *** result. show t.at.t.e GB is an effect.ve solut.on t. allow great.r penet.at.on of VRE generat.on while maint.ining syst.m st.bilit. in t.e NPG.

关键词： Bat.ery energy st.rage syst.m(BESS) grid boost.r t.ansient.st.bilit. volt.ge st.bilit. elect.omagnet.c t.ansient.EMt.

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Glucagon-like pept.de 1 recept.r act.vat.on:ant.-inflammatory effect. in t.e brain

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Neural Regenerat.on Research 2024年第8期19卷 1671-1677页

作者： Yolanda Diz-Chaves Zainab Maast.r Carlos Spuch José Ant.nio Lamas Lucas C.González-matías Federico Mallo Biomedical Research Cent.e(CiNBiO) Laboratory of EndocrinologyUniversity of VigoGalicia Sur Health Research InstituteVigoSpain t.anslat.onal Neuroscience Research Group Galicia Sur Health Research InstituteCIBERSAMHospitalÁlvaro CunqueiroSala InvestigaciónEstrada Clara CampoamorVigoSpain Biomedical Research Cent.e(CiNBiO) Laboratory of NeuroscienceUniversity of VigoGalicia Sur Health Research InstituteVigoSpain

t.e glucagon-like pept.de 1 is a pleiot.opic hormone t.at.has pot.nt.insulinot.opic effect. and is key in t.eat.ng met.bolic diseases such as diabet.s and ***-like pept.de 1 exert. it. effect. by act.vat.ng a membrane recept.r ident.fied in many t.ssues,including diffe rent.brain ***-like pept.de 1 act.vat.s several signaling pat.ways relat.d t. neuroprot.ct.on,like t.e support.of cell growt./survival,enhancement.promot.on of synapse formation,aut.phagy,and inhibit.on of t.e secret.on of proinflammatory cyt.kines,microglial act.vat.on,and apopt.sis during neural *** glial cells,including ast.ocyt.s and microglia,maint.in met.bolic homeost.sis and defe nse against.pat.ogens in t.e cent.al nervous *** brain insult.microglia are t.e first.cells t. respond,followed by react.ve *** act.vat.d cells produce proinflammato ry mediat.rs like cyt.kines or chemokines t. react.t. t.e ***,under t.ese circumst.nces,mic roglia can become chro nically inflammatory by losing t.eir homeost.t.c molecular signat.re and,consequent.y,t.eir funct.ons during many *** processes promot. t.e development.of neurological disorders and influence t.eir pat.ological evolut.on:like t.e formation of prot.in aggregat.s,t.e accumulat.on of abnormally modified cellular const.t.ent.,t.e formation and release by injured neurons or synapses of molecules t.at.can dampen neural funct.on,and,of crit.cal impo rt.nce,t.e dysregulat.on of inflammato ry cont.ol *** glucagonlike pept.de 1 recept.r agonist.emerges as a crit.cal t.ol in t.eat.ng brain-relat.d inflammatory pat.ologies,rest.ring brain cell homeost.sis under inflammatory condit.ons,modulat.ng mic roglia act.vit.,and decreasing t.e inflammato ry *** review summarizes recent.advances linked t. t.e ant.-inflammato ry prope rt.es of glucagon-like pept.de 1 recept.r act.vat.on in t.e brain relat.d t. mult.ple sclerosis,Alzheimer’s disease,Parkins

关键词： ast.ocyt.s brain glucagon-like pept.de 1 recept.r inflammation microglia

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Growt. performance,fat.y acid profile,gut.and muscle hist.-morphology of Malaysian mahseer,t.r t.mbroides post.larvae fed short.t.rm host.associat.d probiot.cs

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Aquacult.re and Fisheries 2024年第1期9卷 35-45页

作者： Mohammod Kamruzzaman Hossain Sairat.l Dahlianis ishak Shumpei iehat. mat Noordin Noordiyana Md Abdul Kader Ambok Bolong Abol-Munafi Depart.ent.of Fisheries(DoF) Matshya BhabonRamnaDhaka1000Bangladesh Higher inst.t.t.on Cent.e of Excellence(HiCoE) Institute of Tropical Aquaculture and Fisheries(AKUATROP)Universiti Malaysia TerengganuKuala Nerus21030Malaysia Facult. of Fisheries and Food Sciences Universiti Malaysia TerengganuKuala Nerus21030Malaysia Alt.rnat.ve Aquat.ch Victoria3029Australia

Host.associat.d probiot.cs(HAPs)provide healt. benefit. t. t.e host.when administ.red as diet.ry ***,a short.t.rm probiot.cs applicat.on st.at.gy has yet.t. be opt.mized.A 90-days st.dy was conduct.d t. evaluat. t.e response of Malaysian mahseer,t.r t.mbroides post.larvae fed wit. basal diet.enriched HAPs for 30-days,and it. response following anot.er 60-days feeding wit. only basal *** experiment.l diet.(Ent.rococcus faecalis st.ain 2674(t.),Aeromonas *** A8-29(t.)and *** st.ain FC11682(t.))were prepared by spray-coat.ng each HAPs on a basal diet.at.1×108 CFU/g *** in growt. performances,whole-body proximate and fat.y acid composit.on,muscle morphomet.y,and gut.morphology were *** showed t.at.aft.r 30 days,t. fish produced highest.*** HAP t.eat.ent.groups showed bet.er muscle dist.ibut.on profile,improved fat.y acid composit.on,and higher villus lengt.,widt. and area,t.an cont.ol *** 90 days,t.e growt. of t. fish was st.ll t.e *** dist.ibut.on profile and villus growt. were higher in HAP t.eat.ent.,alt.ough only t.t.l n-6 PUFA,t.t.l MUFA,linoleic acids,and linolenic acids in HAP t.eat.d fish remained high aft.r probiot.cs *** difference in whole-body proximate composit.on was observed in bot. 30 and 90 *** findings demonst.at.d t.at.short.t.rm applicat.on of HAPs at.an early st.ge could be used t. boost.*** growt.,wit. *** st.ain FC11682 showing t.e best.efficacy.

关键词： Enhance cult.re Ent.rococcus faecalis Aeromonas sp. Muscle hypert.ophy Short.t.rm feeding t.r t.mbroides

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t.e effect. of mixed prebiot.cs in aquacult.re:A review

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Aquacult.re and Fisheries 2024年第1期9卷 28-34页

作者： Wendy Wee Noor Khalidah Abdul Hamid Khairiyah mat Raja ili Airina Raja Khalif Nor Dini Rusli Mohammad Mijanur Rahman Muhammad Anamul Kabir Lee Seong Wei Cent.e for Foundat.on and Cont.nuing Educat.on Universiti Malaysia Terengganu21030Kuala NerusTerengganuMalaysia School of Biological Sciences Universiti Sains Malaysia11800MindenPulau PinangMalaysia Depart.ent.of Agricult.ral Sciences Faculty of Agro-Based IndustryUniversiti Malaysia KelantanJeli Campus17600JeliKelantanMalaysia Facult. of Fisheries Sylhet Agricultural UniversitySylhet3100Bangladesh

Aquacult.re indust.y cont.ibut.s significant.aquacult.re species product.on t. meet.fish prot.in demand from t.e *** indust.y is gearing t.wards int.nsificat.on t. increase more product.on in t.e near *** t.chnologies and effort. were int.oduced int. aquacult.re indust.y t. bring it.up t. t.e next.higher ***,t.e development.of aquacult.re indust.y is hindered by disease *** a result.excessive use of ant.biot.cs and chemicals were applied t. reduce or minimize risk of disease out.reak in aquacult.re farming ***,aquacult.res product. and environment.were highly exposed t. t.ese ant.biot.cs and *** resolve t.is issue,fish farmers were encouraged t. ut.lize alt.rnat.ve met.od in aquacult.re species healt. *** has become a new approach in aquacult.re indust.y t. maint.in aquacult.re species healt. and a good environment.at.t.e same t.me produce chemical and ant.biot.c-free aquacult.re *** t.is review paper,we summarize and discuss t.e effect. of prebiot.c mixt.res administ.at.on on growt. performance,immune response,disease resist.nce,and t.lerance against.abiot.c st.essors of aquat.c animals.

关键词： Growt. performance immunosaccharide Disease resist.nce St.ess relieve

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Cardiovascular risk fact.rs among older persons wit. cognit.ve frailt. in middle income count.y

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World Journal of Clinical Cases 2024年第17期12卷 3076-3085页

作者： Azianah Mohamad ibrahim Devinder Kaur Ajit.Singh Arimi Fit.i mat Ludin Noor ibrahim Mohamed Sakian Nurul Fat.n Malek Rivan Suzana Shahar Cent.e for Healt.y Ageing and Wellness Faculty of Health SciencesUniversiti Kebangsaan MalaysiaWilayah Persekutuan Kuala Lumpur 50300Malaysia Basic Medical Sciences University of CyberjayaSelangor Darul EhsanMalaysia 63000Malaysia

BACKGROUND Cognit.ve frailt.,charact.rized by t.e coexist.nce of cognit.ve impairment.and physical frailt.,represent. a mult.facet.d challenge in t.e aging *** role of cardiovascular risk fact.rs in t.is complex int.rplay is not.yet.fully *** t. invest.gat. t.e relat.onships bet.een cardiovascular risk fact.rs and older persons wit. cognit.ve frailt. by pooling dat. from t.o cohort. of st.dies in *** A comprehensive approach was employed,wit. a t.t.l of 512 communit.dwelling older persons aged 60 years and above,involving t.o cohort. of older persons from previous *** relat.d t. cardiovascular risks,namely sociodemographic fact.rs,and cardiovascular risk fact.rs,including hypert.nsion,diabet.s,hypercholest.rolemia,ant.ropomet.ic charact.rist.cs and biochemical profiles,were pooled for *** frailt. was defined based on t.e Clinical Dement.a Rat.ng scale and Fried frailt. *** risk was det.rmined using Framingham risk *** analyses were conduct.d using SPSS version *** Of t.e st.dy part.cipant.,46.3%exhibit.d cognit.ve *** risk fact.rs including hypert.nsion(OR:1.60;95%Ci:1.12-2.30),low fat.free mass(OR:0.96;95%Ci:0.94-0.98),high percent.ge body fat.OR:1.04;95%Ci:1.02-1.06),high waist.circumference(OR:1.02;95%Ci:1.01-1.04),high fast.ng blood glucose(OR:1.64;95%Ci:1.11-2.43),high Framingham risk score(OR:1.65;95%Ci:1.17-2.31),t.get.er wit. sociodemographic fact.rs,i.e.,being single(OR 3.38;95%Ci:2.26-5.05)and low household income(OR 2.18;95%Ci:1.44-3.30)were found t. be associat.d wit. cognit.ve *** Cardiovascular-risk specific risk fact.rs and sociodemographic fact.rs were associat.d wit. risk of cognit.ve frailt.,a prodromal st.ge of *** ident.ficat.on and management.of cardiovascular risk fact.rs,part.cularly among specific group of t.e populat.on might.mit.gat. t.e risk of cognit.ve frailt.,hence prevent.ng dement.a.

关键词： Cognit.ve frailt. Older persons Cardiovascular risk fact.rs Frailt. Mild cognit.ve impairment

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Effect. of Spark Energy on Spark Plug Fault.Recognit.on in a Spark ignit.on Engine

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Energy Engineering 2022年第1期119卷 189-199页

作者： A.A.Azrin i.M.Yusri M.H.mat Yasin A.Zainal Facult. of Mechanical and Aut.mot.ve Engineering t.chnology Universiti Malaysia PahangPekan26600Malaysia Cent.e for Aut.mot.ve Engineering Universiti Malaysia PahangPekan26600Malaysia Aut.mot.ve t.chnology Cent.r(At.C) Politeknik Sultan Mizan Zainal AbidinDungun23000Malaysia Aut.mot.ve Engineering Depart.ent.Educat.on Engineering FacultyUniversitas Negeri YogyakartaYogyakarta55281Indonesia

t.e increasing demands for fuel economy and emission reduct.on have led t. t.e development.of lean/dilut.d combust.on st.at.gies for modern Spark ignit.on(Si)*** new generat.on of Si engines requires higher spark energy and a longer discharge durat.on t. improve efficiency and reduce t.e ***,t.e increased spark energy gives negat.ve impact. on t.e ignit.on syst.m which result. in det.riorat.on of t.e spark ***,a numerical model was used t. est.mate t.e spark energy of t.e ignit.on syst.m based on t.e breakdown *** t.end of spark energy is t.en recognized by implement.ng t.e classificat.on *** feat.res were ident.fied from t.e information Gain(iG)scoring of t.e st.t.st.cal analysis.k-Nearest.Neighbor(KNN),Art.ficial Neural Net.ork(ANN),and Support.ect.r Machine(SVM)models were st.died t. ident.fy t.e best.classifier for t.e classificat.on *** all classifiers,t.e ent.re feat.red dat.set.was randomly divided int. st.ndardized paramet.r values of t.aining and t.st.ng dat. set. wit. t.e rat.o of 70-30 for each *** was shown in t.e st.dy t.at.t.e KNN classifier acquired t.e highest.Classificat.on Accuracy(CA)of 94.1%compared t. ANN and SVM t.at.score 77.3%and 87.9%on t.e t.st.dat.,respect.vely.

关键词： Spark energy numerical model breakdown volt.ge fault.recognit.on classificat.on

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Physiot.erapy Management.of Rheumatic Diseases

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Open Journal of Rheumatology and Aut.immune Diseases 2024年第1期14卷 37-47页

作者： Aly Badra Kamissoko Abdoulaye Barry Mamadou Lamine Diallo Bout.os Cosme Nat. Abdel Amide Gbadamassi Marie t.aore Abèni Faouzyat. Yaya Facely t.aore Paul Eloundou Sory Diane matènè Komara Halimatou Barry Moriba t.ure Moriba t.ure Kaba Conde Owonayo Oniankit.n Depart.ent.of Rheumatology Ignace Deen University Hospital Conakry Guinea Depart.ent.of Rheumatology Sylvanus Olympio University Hospital Lome Togo Facult. of Medicine and Pharmaceut.cal Sciences University of Douala Douala Cameroon

int.oduct.on: Physiot.erapy is an int.gral part.of t.e non-drug t.eat.ent.st.at.gy for rheumatological condit.ons. t.e evidence for it. effect. is not.formal. t.e object.ve was t. evaluat. t.e impact.of physiot.erapy in t.e management.of rheumatological disorders. Met.ods: 6-mont. case-cont.ol st.dy (December 15, 2021 t. June 20, 2022) at.ignace Deen Universit. Hospit.l (Conakry). Pat.ent. wit. rheumatological disease who received drug t.erapy and physiot.erapy were included in t.e case group. Age- and sex-matched cont.ols had rheumatological condit.ons, t.eat.d wit.out.physiot.erapy. t.e evaluat.on quest.onnaires were used: WOMAC (ost.oart.rit.s), EiFEL (low back pain), NDi (neck pain), SPADi (shoulder). Pat.ent. wit. heart.failure, respirat.ry failure and/or skin infect.on were not.included. Result.: We collect.d 773 pat.ent. (389 cases and 384 cont.ols) wit. a mean age of 53.8 years ± 12.2 wit. female predominance (56.8%). Pat.ent. were mainly followed for ost.oart.rit.s (65.2%). Rheumatological condit.ons managed were knee-based (119;30.6%), lumbar spine (220;56.6%), shoulders (27;6.9%) and cervical spine (23;5.9%). For an average durat.on of 53.4 ± 12.2 minut.s per session, pat.ent. had benefit.d from a median of 19 physiot.erapy sessions. Aft.r 3 mont.s, t.e baseline mean VAS of 6/10 improved t. 2.2 ± 1.6 for cases and 5.7 ± 1.2 for cont.ols. Funct.onal capacit. was improved (WOMAC: 41.8 ± 22.7 vs. 18.3 ± 7.3). t.e sat.sfact.on of pat.ent. t.eat.d wit. physiot.erapy was 20 t.mes higher t.an in cont.ols. Conclusion: Physiot.erapy performed in t.e management.of rheumatological condit.ons significant.y reduced pain and improved funct.onal capacit..

关键词： Rheumatological Disease Physiot.erapy WOMAC Guinea

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Et.ical and legal implicat.ons of gene edit.ng in plant.breeding:a syst.matic lit.rat.re review

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Journal of Zhejiang Universit.-Science B(Biomedicine & Biot.chnology) 2023年第12期24卷 1093-1105页

作者： Sit. Hafsyah iDRiS Nurzat.l Sharleeza mat JALALUDDiN Lee Wei CHANG Facult. of Law Universiti Teknologi MARAJalan Sarjana 1/2Shah Alam 40450SelangorMalaysia Cent.e for Research in Biot.chnology for Agricult.re(CEBAR) Level 3Research Management and Innovation ComplexUniversiti MalayaKualaLumpur50603Malaysia Cent.e for Civilisat.onal Dialogue Level 1High Impact Research BuildingUniversiti MalayaKuala Lumpur 50603Malaysia

Biot.chnology policies and regulat.ons must.be revised and updat.d t. reflect.t.e most.recent.advances in plant.reeding t.chnology. New Plant.Breeding t.chniques(NPBt. such as gene edit.ng have been applied t. address t.e myriad of challenges in plant.breeding, while t.e use of NPBt.as emerging biot.chnological t.ols raises legal and et.ical concerns. t.is st.dy aims t. highlight.how gene edit.ng is operat.onalized in t.e exist.ng lit.rat.re and examine t.e crit.cal issues of et.ical and legal issues of gene edit.ng for plant.breeding. We carried out.a syst.matic lit.rat.re review(SLR) t. provide t.e current.st.t.s of et.ical and legal discourses surrounding t.is t.pic. We also ident.fied crit.cal research priorit. areas and policy gaps t.at.must.be addressed when designing t.e fut.re governance of gene edit.ng in plant.breeding.

关键词： Syst.matic lit.rat.re review Gene edit.ng Plant.breeding Et.ical and legal issues Consequent.alism Virt.e et.ics principles

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impact.of work environment.on job sat.sfact.on and st.ess among hemodialysis st.ff in Klang Valley

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Front.ers of Nursing 2023年第4期10卷 481-492页

作者： Zaima mat Yusuf Bit.Lian Yee Nat.onal Guard Healt. Affairs King Abdul Aziz Medical CityNursing Education ServicesRiyadh 11426Kingdom of Saudi Arabia Facult. of t.chnology and Applied Sciences Open University MalaysiaPetaling JayaSelangor 47301Malaysia

Object.ve:t. invest.gat. t.e fact.rs cont.ibut.ng t. sat.sfact.on wit. t.e work environment.job sat.sfact.on(JS),and st.ess among hemodialysis(HD)st.ff in t.e cent.al region of ***:A quant.t.t.ve cross-sect.onal st.dy was conduct.d on 215 HD st.ff working at.privat. and non-government.NGO)dialysis cent.rs using self-administ.red *** chi-square t.st.was used t. det.rmine fact.rs associat.d wit. HD st.ff's JS,st.ess,and working ***:t.e scient.fic proof was apparent.t.at.t.e working environment.had an effect.on JS and st.ess among employees at.HD ***:t.is research offers useful insight. int. t.e essence and complexit.es of HD st.ff's work and will help nurses,dialysis managers,ot.er dialysis personnel,and organizat.ons t. bet.er underst.nd t.e benefit. and st.esses faced by t.ese workers.

关键词： hemodialysis st.ff job sat.sfact.on nurses st.ess work environment

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