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Acidity, electric Conductivity, Dissolved Oxygen Total Dissolved Solid and Salinity Profiles of Marine Water in Gaza: Influence of Wastewater Discharge

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American Journal of Analytical Chemistry 2021年第11期12卷 408-428页

作者： dalia el nahhal Ibrahim el-nahhal Husam Al Najar Mohammad Al-Agha Yasser el-nahhal Faculty of Health Sciences Islamic University of Gaza Gaza Strip Palestine Université de Toulon Toulon France Department Environment and Earth Science Faculty Science Islamic University of Gaza Gaza Strip Palestine

Effects of wastewater discharge on the coastal area in Gaza strip Palestine are not fully investigated. This study investigated the effect wastewater discharge of the physical and chemical properties of marine water in the coastal area over a period of 2 year. Sea water and sediment samples were collected from about 20 different sites. The water and the sediments were collected wastewater/sea water mixing zone at depth 0, 2.5 and 5 m water column depth at a direct wastewater discharging pipe line from different location and similarly from other locations. Water temperature T, electric conductivity (EC), dissolved oxygen (DO), pH, total dissolved solid (TDS) and salinity were determined for water samples using field equipment such as pH-meter, DO meter, TDS-/ and EC-meter. On the other hand, NO3-, SO42-, PO43- were determined in the laboratory using chemical methods, details are described in materials and method section. Results showed average and standard deviation of T, EC, DO, pH, TDS and salinity were 22.02°C ± 4.1°C, EC: 58.41 ± 4.8 ms/cm;DO: 6.96 ± 1.8 mg/L;pH: 7.69 ± 0.37;TDS: 30.51 ± 3.29 and salinity 4.39 ± 0.12 (%);whereas, average and standard deviation of NO3-: were 299.8 ± 204.1 mg/L;SO42-, 5736.9 ± 817.1;and PO43-: 164.35 ± 120.7 mg/L. The measured values indicate significant differences due to high value of standard deviation of some measured parameters. This indicates the influence of wastewater discharge in sea water as shown inside the manuscript in the appropriate section. The study recommends efficient treatment of wastewater and reuses it for agricultural purposes instead of discharging it in sea.

关键词： Seawater Wastewater Marine Sediments Shellfish DO TDS NO3- SO42- PO43-

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Rapid Method for Greywater Treatment and Their Potential Reuse in Agriculture

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American Journal of Analytical Chemistry 2022年第2期13卷 20-38页

作者： Eman Mahmoud el Qrenawi Ibrahim el-nahhal Mohamad R. Al-Agha Yasser el-nahhal Department of Environmental Science Faculty of Science The Islamic University-Gaza Gaza Palestine Université de Toulon Aix-Marseille Université La Garde France

Greywater, a type of wastewater, may be hazardous to human health and ecosystems. Greywater is a large fraction of wastewater that needs adequate attention for remediation and reuse in the agricultural sector so that a part of the water problem can be sorted out. This study aims to develop a rapid method for greywater treatment and reuse in agriculture. A microfilter consisting of sand, clay, organo-clay, charcoal, and biochar was designed and tested for greywater treatments. Biological Oxygen Demand (BOD), Chemical Oxygen Demand (COD), Total Kjeldahl Nitrogen (TKN), Total Dissolved Salts (TDS), electric Conductivity (EC), turbidity and pH values were measured before and after using the microfilter. Results showed tremendous removal efficiency of BOD, COD, TKN, by using the developed microfilter. The microfilter was also effective in treating and placing pH, EC and TDS in the acceptable range for suitable agricultural use. Using the treated greywater for irrigation in corn, tomato seedlings showed increased growth compared with the control group (plants irrigated with tap water). This microfilter treatment was economical, safe, easy to handle and easily applicable. These encouraging results suggest the application of this method in many countries for solving the water scarcity problem.

关键词： Greywater Microfilter Sea Sand Organoclay Biochar Charcoal Sawdust

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Serologic, endoscopic and pathologic findings in pediatric celiac disease: A single center experience in a low/middle income country

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World Journal of Clinical Pediatrics 2022年第3期11卷 295-306页

作者： Hala H Mansour Nabil A Mohsen Mortada HF el-Shabrawi Somia M Awad dalia Abd el-Kareem Department of Pediatrics Faculty of Medicine Kasr Al AinyCairo UniversityCairo 12411Egypt Department of Pathology Cairo UniversityCairo 11562Egypt

BACKGROUND Studies in Africa,Asia,and Latin America are needed to provide a comprehensive picture of the global incidence of celiac disease(CD).AIM To describe the serology,endoscopic and histological findings in typical and atypical presentations of pediatric CD at a tertiary referral hospital in an African low/middle income country(LMIC).METHODS This observational study was conducted on 199 patients with CD from 2010 to *** patients were divided into typical and atypical groups according to the presenting symptoms including 120 and 79 patients ***,upper gastrointestinal endoscopy with duodenal biopsy were performed for patients who had symptoms suggestive of *** severity of the intestinal damage was graded according to the histo-pathologic Marsh-Oberhuber *** Chronic diarrhea was the main intestinal presentation in the typical *** was the most common extraintestinal symptom in both the typical and atypical ***-Oberhuber type 3b and 3c was significantly higher in the seropositive patients with a P value of 0.007.A significant correlation was observed between the histological grade of the biopsied duodenal mucosa and the clinical presentation(P<0.001).Age was significantly higher in the atypical group(P value<0.001).CONCLUSION Although typical CD was observed in 120 patients in this study,the clinical variability of the condition was frequently *** only was a significant predictor for the appearance of atypical ***,CD presentations in LMIC are not different from industrialized countries.

关键词： Typical Atypical celiac disease Celiac serology Marsh-Oberhuber histopathology

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Studies on the anti-aging properties of bovine whey supplementation on reproductive hormonal profiles and sperm structure and function of adult and senile rats

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Food Bioscience 2022年第1期45卷 301-312页

作者： Norhan TAH.Kandil dalia AA.Sabry Nermeen IE.Ashry Hassan IH.el-Sayyad Zoology Department Faculty of ScienceMansoura UniversityEgypt

The purpose of this study was to investigate how well whey might protect against aging related alterations in sperm structure,seminal and antioxidant enzymes and serum hormonal *** Wistar albino rats aged 8 and 30-months were divided into two primary groups with or without whey supplementation(n=8).After the experiments of whey supplementation,the rats were euthanized,blood was collected,and serum was *** ultrastructure and flow cytometry of annexin-V and mitochondrial membrane potential were carried *** antioxidant and malondialdehyde concentrations were *** hormonal profiles of testosterone,growth(GH),follicle stimulating hormone(FSH),luteinizing hormone(LH)and thyroid stimulating hormone(TSH)as well as pituitary gland ultrastructure were *** showed that whey supplementation improved the structure and function of sperm and seminal fluid as well as the serum hormonal levels of *** aged rats,whey supplementation increased the serum levels of GH,FSH,LH and TSH as well as seminal superoxide *** supplementation also caused reduction of seminal alkaline and acid phosphatases and lipid peroxidation in aged rat compared to that in adult *** also improved sperm motility and viability but reduced sperm abnormalities by increasing sperm mitochondrial membrane potential and lowering annexin v *** conclusion,whey contains antioxidant components that alleviated oxidative stress involved in damaging sperm macromolecules during aging process.

关键词： Aging Sperm Seminal fluid Pituitary Hormones

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Ovarian hyperstimulation syndrome following the use of GnRH agonist trigger of final oocyte maturation and freeze-all strategy: A case report and review of the literature

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Asian pacific Journal of Reproduction 2022年第6期11卷 292-298页

作者： dalia Khalife Suleiman Ghunaim Lina el Taha Omar Odeh Natasha Habr Johnny Awwad Department of Obstetrics and Gynecology Division of Reproductive Endocrinology and InfertilityHaifa Idriss-ART UnitAmerican University of BeirutBeirutLebanon School of Medicine The University of JordanAmmanJordan Division of Plastic and Reconstructive Surgery American University of Beirut Medical CenterBeirutLebanon

Rationale:The current literature has a surprising controversy regarding the use of low-dose human chorionic gonadotropin(hCG)for luteal support as an explanation for the development of ovarian hyperstimulation syndrome,and this is because of the gap in the listing of the predisposing factors that put women at an increased risk of ovarian hyperstimulation *** concerns:A case of 25-year-old woman presented with abdominal pain,distention,dyspnea,and nausea with a 6.5 kg increase in weight from *** examination showed bilaterally enlarged multicystic ovaries after gonadotropin-releasing hormone(GnRH)agonist triggering and cycle segmentation with no hCG rescue ***:Moderate/severe ovarian hyperstimulation ***:The woman was admitted to the hospital for medical management of moderate/severe ovarian hyperstimulation syndrome,and pain management was advanced to patient-controlled anesthesia with the start of low molecular weight *** day 2,albumin therapy followed by a furosemide chase was started due to an increase in abdominal *** day 1,Cabergoline was maintained,and on day 2 the GnRH antagonist Cetrorelix was ***:The woman’s clinical condition improved,and a clinical pregnancy was eventually achieved during the first cryo-warmed blastocyst ***:Ovarian hyperstimulation syndrome can still happen even after the use of GnRH agonist and avoidance of hCG *** of in vitro fertilization with complete avoidance of hCG for luteal support remains the best approach.

关键词： Ovarian hyperstimulation syndrome Gonadotropin releasing hormone agonist In vitro fertilization Human chorionic gonadotropin support Ovulation induction Reproductive endocrinology

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The Effect of Atrial Septal Defect Closure on Cardiac Volumetric Changes in Adults, Transcatheter Versus Surgical Closure, a Pilot Cardiac Magnetic Resonance Study

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Congenital Heart Disease 2023年第6期18卷 679-691页

作者： Amr Mansour Noha M.Gamal Alaa M.Nady Amr Ibraheem dalia M.Salah Khaled M.el-Maghraby Cardiology Department Congenital and Structural Heart Disease UnitAin Shams University HospitalsFaculty of MedicineAin Shams UniversityCairoEgypt Cardiology Department Faculty of MedicineAssuit UniversityAssuitEgypt Cardiothoracic Surgery Department Faculty of MedicineAssuit UniversityAssuitEgypt Anesthesia Department Faculty of MedicineAssuit UniversityAssuitEgypt

Background:Closure of an atrial septal defect(ASD)reduces right-side heart volumes by abolishing shunting with simultaneous improvement of the left ventricle(LV)ﬁlling and functions due to ventricular interdependence,thereby improving ***,studies conducted on atrial volume changes after ASD closure are *** magnetic resonance(CMR)is considered as the gold standard method for measuring cardiac volume and ***:We aimed to study the effect of transcatheter and surgical closure of secundum ASD on cardiac volumes and systolic functions as well as the fate of tricuspid regurgitation(TR),using CMR ***:We prospectively enrolled 30 adult patients with isolated secundum ASD who were referred to ASD *** evaluation of cardiac chambers indexed volumes,systolic function,myocardial mass index,and tricuspid regurgitant fraction were done at before and 6 months after ***:RV volumes decreased in both groups when compared to baseline(p-value 0.001),the device group had more reduction in volumes and more improvement in RV function after closure(p-value 0.001)when compared to the surgical *** changes in the RV mass index were insigniﬁcant between both groups(p-value 0.31).Functional TR improved to the same extent in both *** ventricular end diastolic volume index(LVEDVI)and LV mass index increased sig-niﬁcantly in both groups when compared to baseline in both groups but with no difference between groups p-value 0.01),left ventricular end systolic volume index(LVESVI)changes were insigniﬁ*** systolic function improved in patients who underwent device closure only(63.53±3.85 vs.67.13±4.34,p-value 0.01).There was a signiﬁcant reduction in right atrial(RA)volumes and an insigniﬁcant decrease in left atrial(LA)volumes,with no difference between ***:Transcatheter and surgical secundum ASD closure resulted in volumetric changes in some cardiac chambers with better improvement in bi-ventricular

关键词： Atrial septal defect closure cardiac volumetric changes functional tricuspid regurgitation cardiac CMR

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Extraction Methods of Cyanotoxins Aqueous Media and Sediments

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American Journal of Analytical Chemistry 2021年第9期12卷 311-323页

作者： Hala el-nahhal Maged Yassin Mazan Alzaharna Ibrahim el-nahhal Yasser el-nahhal Faculty of Health Sciences Islamic University of Gaza P.O. Box 108 Gaza Palestine Université de Toulon Toulon France Department Environment and Earth Science Faculty Science Islamic University of Gaza P.O. Box 108 Gaza Palestine

Cyanotoxins are chemical compounds produced by cyanobacterial mats grown in aquatic ecosystems. These may threaten human health and aquatic organisms. Extraction of these toxins is usually associated with many difficulties due to their concentration in aquatic ecosystems. This study is designed to provide suitable and effective extraction procedures that can effectively extract low concentration cyanotoxin from water and bacterial cells. The methodology is based on collecting raw material of cyanobacterial mats from naturally growing sites such as Wadi Gaza along with 16 liters of aquatic surrounding media. The materials were left in the Lab for 24 - 48 h for stabilization of the mats. The floating mats were collected using special funnel and allowed to air drying. The aqueous phase was extracted by liquid/liquid extraction using solvent mixture (hexane + ethylacetate 10% w:w), and by liquid solid extraction using several types of organoclays complexes. The solid phase was extracted by acetone and ultrasonic device. Results showed some difficulties were associated with liquid/liquid extraction whereas effective and easy extraction procedures were obtained by liquid solid extraction using either organoclay complex or activated charcoal. In contrast combination of both solid materials did not show improvement in the extracted cyanotoxin. Thus we recommend the use of organoclays or activated charcoal separately for extracting cyanotoxin. Further improvement of extraction can be tailored by using a specific organoclay complex that has some similarity in the chemical structure between the pre-adsorbed organic cation to the clay mineral and the chemical structure of cyanotoxin.

关键词： Cyanobacteria Cyanotoxins Extraction Organoclays

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Cardiotoxicity among Children Accidentally Exposed to Organophosphate Insecticides Coupled with Scorpion Bites in Gaza

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Health 2021年第9期13卷 1045-1063页

作者： Yasser el-nahhal Ibrahim el-nahhal Department of Earth and Environmental Science Faculty of Science Islamic University of Gaza Gaza Palestine Université de Toulon Toulon France

Insecticides are toxic chemicals used at homes for controlling insects of public health importance and controlling agricultural pests at home gardens. Their application may result in accidental poisoning. Four accidental insecticide-poisoning children coupled with a scorpion bitten child were brought to the main hospital in southern Gaza for medical treatment. Primary investigation showed severe breath shortness, low heartbeat, and low blood pressure (hypotension). These symptoms are indications of potential cardiotoxicity among children. electrocardiograms were measured and indicated various heart complications between cases. Complete blood count (CBC) determination showed the highest white blood cells (WBC) in the scorpion-bitted child suggesting the development of immune defense system. Blood electrolyte (Na+, K+, Ca2+) concentrations indicated disturbances due to poisoning. An interesting outcome of the study is the dramatic alteration in blood glucose concentration. Additionally, activity of acetylcholinesterase (AChE) indicated normal activity in poisoning case 1, moderate inhibition in poisoning case 2 and case 3, normal activity in poisoning case 4 and severe inhibition in poisoning case 5. The levels of Aminotransferase (ALT) and Aspartate Aminotransferase (AST) were within the acceptable range whereas the level of Alkaline Phosphatase (ALP) was above the acceptable reference range suggesting potential Hepato-toxicity. Scorpion bitten child did not receive atropine whereas two poisoned cases were successfully cured by atropine injection. Additionally, alternative safe medical management may be used for cardiotoxicity using vitamin C, vitamin E, quercetin, and curcumin. These vitamins may be recommended as alternative medical treatments for cardiotoxicity.

关键词： Component Insecticides Cardiotoxicity Children Scorpion Bites

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Epidemiological,clinical and laboratory findings of infectious keratitis at Mansoura Ophthalmic Center,Egypt

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International Journal of Ophthalmology(English edition) 2017年第1期10卷 61-67页

作者： Amani E Badawi dalia Moemen Nora L el-Tantaw Departrnent of Ophthalmology Faculty of MedicineMansouraUniversityMansoura 35516Egypt Department of Medical Microbiology and Immunology Faculty of MedicineMansoura UniversityMansoura 35516Egypt Department of Parasitology Faculty of MedicineMansouraUniversityMansoura 35516Egypt

AIM： To analyze the epidemiological, clinical and laboratory findings of infectious ***： A retrospective study on cases of infective keratitis, attended our institution from Mar. 2013 to Feb. 2015, was done at Mansoura Ophthalmic Center, Egypt. Corneal scrapings were performed and processed for direct microscopy and culture in appropriate media using standard laboratory ***： Out of 245 patients enrolled for study, 247 corneal scrapings were obtained. Ocular trauma was the most common predisposing factor （51.4%）, followed by diabetes mellitus （15.1%）. Cultures were positive in 110 scraping samples （44.5%）： 45.5% samples had pure fungal infection, 40% had pure bacterial infections and 10% had mixed fungal and bacterial growths. Acanthamoeba was detected in 5 （4.5%） samples. The most common fungal pathogen was Aspergillus spp. （41%）. The most common bacterial isolates were Staphylococcus aureus （38.2%） and Pseudomonas aeruginosa （21.8%）.CONCLUSION： Incidence of fungal keratitis is high in our region. Therapeutic approach can initially be based on clinical features and sensitivity/resistance patterns. Microbiological research should direct the antimicrobial treatment. Antibiotic resistance to fluoroquinolones and aminoglycosides is an important consideration.

关键词： infectious keratitis bacterial fungal parasitic predisposing factors antibiotic resistance

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Identification of functional tumor necrosis factor-alpha promoter variants associated with Helicobacter pylori infection in the Sudanese population: Computational approach

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World Journal of Gastroenterology 2022年第2期28卷 242-262页

作者： Abeer Babiker Idris Alaa B Idris Manal A Gumaa Mohammed Babiker Idris Amanda elgoraish Mohamed Mansour dalia Allam Bashir MO Arbab Nazar Beirag el-Amin M Ibrahim Mohamed A Hassan Department of Agricultural Science and Technology Institute of Natural and Applied SciencesErciyes UniversityKayseri 38039Turkey Department of Medical Microbiology Faculty of Medical Laboratory SciencesUniversity of KhartoumKhartoum 11111Sudan Department of Neurosurgery Ribat University HospitalKhartoum 11111Sudan BioMérieux Clinical and Application Advisor Al-Jeel Medical Co.Riyadh 11422Saudi Arabia Department of Epidemiology Tropical Medicine Research InstituteKhartoum 11111Sudan Department of Gastroenterology Ibn Sina Specialized HospitalKhartoum 11111Sudan Department of Gastroenterology Modern Medical CentreKhartoum 11111Sudan Biosciences College of HealthMedicine and Life SciencesBrunel UniversityLondon UB83PHUxbridgeUnited Kingdom Department of Translation Bioinformatics Detavax BiotechKayseri 38350Turkey

BACKGROUND Helicobacter pylori(***)is a ubiquitous bacterium that affects nearly half of the world’s population with a high morbidity and mortality *** within the tumor necrosis factor-alpha(TNF-A)promoter region are considered a possible genetic basis for this *** To functionally characterize the genetic variations in the TNF-A 5’-region(-584 to+107)of Sudanese patients infected with *** using in silico *** An observational study was carried out in major public and private hospitals in Khartoum state.A total of 122 gastric biopsies were taken from patients who had been referred for *** DNA was *** of the TNF-A-1030 polymorphism was performed using PCR with confronting two-pair primer to investigate its association with the susceptibility to *** infection in the Sudanese ***,Sanger sequencing was applied to detect single nucleotide polymorphisms in the 5’-region(-584 to+107)of TNF-A in ***-infected *** analyses were used to predict whether these mutations would alter transcription factor binding sites or composite regulatory elements in this region.A comparative profiling analysis was conducted in 11 species using the ECR browser and multiple-sequence local alignment and visualization search engine to investigate the possible ***,a multivariate logistic regression model was constructed to estimate odds ratios and their 95%confidence intervals for the association between TNF-A-1030,sociodemographic characteristics and *** *** were statistically significant if PA,-76)was located at the in silico-predicted promoter region(-146 to+10),and it was predicted to alter transcription factor b

关键词： 5’-region Promoter TNF-A Helicobacter pylori In silico analysis Sudan

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