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STUDIES ON THE SYNTHESIS OF NOVEL ISONUCLEOSIDE FROM D-GLUCOSE

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Chinese Chemical Letters 1995年第8期6卷 655-656页

作者： Yu, hw Ma, LT Zhang, LH Beijing Med Univ Sch Pharmaceut Sci Beijing 100083 Peoples R China

A novel isonucleoside, 2,5-anhydro-4-(adenine-9-yl-)-L-iditol was synthesized from D-glucose through 9 steps.

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Measuring gravitational effect of superintense laser by spin-squeezed Bose-Einstein condensates interferometer

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Chinese Physics B 2022年第5期31卷 265-273页

作者： Eng Boon ng C.H.Raymond Ooi Department of Physics University of MalayaKuala Lumpur 50603Malaysia

We consider an extremely intense laser,enclosed by an atom *** gravitational potential generated from the high-intensity laser is solved from the Einstein field equation under the Newtonian *** compute the strength of the gravitational force and study the feasibility of measuring the force by the atom *** intense laser field from the laser pulse can induce a phase change in the interferometer with Bose-Einstein *** push up the sensitivity limit of the interferometer with Bose-Einstein condensates by spin-squeezing effect and determine the sensitivity gap for measuring the gravitational effect from intense laser by atom interferometer.

关键词： intense laser field atom interferometer Bose-Einstein condensates spin-squeezing

一种基于深度学习的新型针灸针自动计数的云服务系统:提高针灸安全性的策略

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Digital Chinese Medicine 2024年第1期7卷 40-46页

作者：黄梓皓韦君逸陈海勇吴凤亮香港大学李嘉诚医学院中医药学院中国香港999077 Department of Mathematics and Statistics Georgetown UniversityWashington D.C.20057USA 香港理工大学康复科学系中国香港999077

目的病人针灸治疗时,漏针可能造成严重后果。为增强针灸安全性,本研究将开发一个基于深度学习的自动云端数针系统。方法本研究利用拍有针灸针的手机图片为曾预先训练的定向目标检测模型(Oriented R-CNN)进行转移学习,以开发一种能够自... 详细信息

目的病人针灸治疗时,漏针可能造成严重后果。为增强针灸安全性,本研究将开发一个基于深度学习的自动云端数针系统。方法本研究利用拍有针灸针的手机图片为曾预先训练的定向目标检测模型(Oriented R-CNN)进行转移学习,以开发一种能够自动计算图片中针灸针数量的目标检测算法。我们首先拍摄了一个包含590张图片的训练集以及一个包含1025张图片的验证集。随后在带有NVIDIA Tesla T4图形处理器(GPU)的Google Colab环境中部署了MMRotate工具箱为模型进行训练。我们将训练的模型与Telegram bot手机小程序界面集成,并评估模型的准确率、精确率和召回率。本小程序中云端数针系统的速度则以端到端处理时间计算。结果在每张图片20根针的验证集情景中,我们的定向检测模型在准确率、精确率和召回率上分别达到96.49%、99.98%和99.84%,平均端到端处理时间为1.535秒。结论这项云服务系统在速度、准确性和可靠性上的提升展示了深度学习物体检测技术改进针灸实践的潜力。

关键词：人工智能电脑视觉目标检测针灸病人安全

Sishengtang decoction in alleviation of toxic and side effects of transarterial embolization

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World Journal of Gastroenterology 1998年第2期4卷 79-81页

作者： Chen, Z Ling, CQ Huang, XQ Zhang, hw Second Mil Med Univ Changhai Hosp Dept Tradit Chinese Med Shanghai 200433 Peoples R China

AIM To observe the therapeutic effects of Sishengtang decoction in alleviating the toxic and side effects of transarterial embolization (TAE). METHODS Fifty four patients with liver cancer were divided randomly into Sishengtang decoction group (34 cases) and control group (20 cases). The changes of clinical symptoms and peripheral hemogram and some cellular immune functions were observed before and two weeks after TAE. RESULTS Sishengtang decoction was superior to the control group in improving the digestive tract reaction. The leucocytes of peripheral blood and cellular immune functions (activities of NK cells and LAK cells) of control group decreased obviously after TAE, while that of Sishengtang decoction group decreased slightly, without obvious difference as compared with that of preoperation. CONCLUSIONS Sishengtang decoction might improve the clinical symptoms and increase the leucocytes of peripheral blood and the cellular immune functions of TAE patients.

关键词： Sishengtang decoction liver neoplasms/therapy embolization, therapeutic immunity , cellular killer cell, natural killer cell , lymphokine activated leucocytes

NUMERICAL SIMULATION OF 3-D DENSE SOLID-LIQUID TWO-PHASE TURBULENT FLOW IN A NON-CLOGGIng MUD PUMP

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Chinese Journal of Mechanical Engineering 2004年第4期17卷 623-627页

作者： YuanShouqi ZhangPei~ng ZhangJinfeng XuWeixinq ResearchCenterofFluidMachine~EngineeringandTechnology JiangsuUniversityZhenjiang212013China

A mathematical model is set to evaluate the 3-D dense solid-liquid two-phaseturbulent flow in a non-clogging mud pump, the flow feature in the impeller channel is simulatedwith the tool of IPSA. Meanwhile, resort to TECPLOT as the post-processor, the simulation results isvisualized. The results show the main flow characteristics: There exists backflow and aberrantvelocities at inlet area and a relative velocity slip between two phases; A jet-wake flow pattern isdiscerned around the shroud-suction side area; The relative velocity vector of solid phase iscloser to the pressure surface than that of liquid phase and the trend is more obvious with theincrease of diameter; The kinetic energy of turbulence k and the dissipation rate e reach theirpeaks at the corner of pressure and suction surface. The simulation results show a good agreementwith the experimental flow features in the impeller channel, which prove the turbulent model used isvalid and provide a theoretical design basis to non-clogging pumps.

关键词： Non-clogging pump Two-phase flow Turbulent flow Numerical simulation

Transdermal drug delivery systems in diabetes management: A review

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Asian Journal of Pharmaceutical Sciences 2020年第1期15卷 13-25页

作者： Li Ching ng Manish Gupta School of Pharmacy Monash University MalaysiaBandar Sunway 47500Malaysia Faculty of Pharmacy DIT UniversityDehradun 248009India

Diabetes mellitus is a chronic disease in which there is an insufficient production of insulin by the pancreas, or the insulin produced is unable to be utilized effectively by the body. Diabetes affects more than 415 million people globally and is estimated to strike about 642 million people in 2040. The WHO reported that diabetes will become the seventh biggest cause of mortality in 2030. Insulin injection and oral hypoglycemic agents remain the primary treatments in diabetes management. These often present with poor patient compliance. However, over the last decade, transdermal systems in diabetes management have gained increasing attention and emerged as a potential hope in diabetes management owing to the advantages that they offer as compared to invasive injection and oral dosage forms. This review presents the recent advances and developments in transdermal research to achieve better diabetes management. Different technologies and approaches have been explored and applied to the transdermal systems to optimize diabetes management. Studies have shown that these transdermal systems demonstrate higher bioavailability compared to oral administration due to the avoidance of first-pass hepatic metabolism and a sustained drug release pattern. Besides that, transdermal systems have the advantage of reducing dosing frequency as drugs are released at a predetermined rate and control blood glucose level over a prolonged time, contributing to better patient compliance. In summary, the transdermal system is a field worth exploring due to its significant advantages over oral route in administration of antidiabetic drugs and biosensing of blood glucose level to ensure better clinical outcomes in diabetes management.

关键词： Transdermal Diabetes Antidiabetic Insulin Drug delivery system

Protein deacetylases and axonal regeneration

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Neural Regeneration Research 2015年第6期10卷 870-871页

作者： Fanny ng Bor Luen Tang Department of Biochemistry Yong Loo Lin School of MedicineNational University Health System Graduate School for Integrative Sciences and Engineering National University of Singapore

A neuron with injured or severed axon responds with attempts at axonal regrowth. In this regard, axonal regeneration of peripheral nerves occurs far more efficiently compared to central nervous system （CNS） neurons. The latter typically could not form a proper growth cone, and any axonal regeneration in vivo is very limited. The adult CNS environment is not conducive for axonal regrowth. An extensive body of work has revealed mechanisms whereby the myelin-associated inhibitors and extracellular matrix chondroitin sulfate proteoglycans promote collapse of axonal growth cones or repel their advances （Lee and Zheng, 2012）. The intrinsic axonal regeneration capacity of an injured neuron is, however,

关键词： Protein deacetylases axonal regeneration

ON ALGORITHMS FOR AUTOMATIC DEBLURRIng FROM A SIngLE IMAGE

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Journal of Computational Mathematics 2012年第1期30卷 80-100页

作者： Wei Wang Michael K.ng Department of Mathematics Tongji UniversityShanghai 200092China Centre for Mathematical Imaging and Vision and Department of Mathematics Hong Kong Baptist UniversityKowloon TongHong KongChina

In this paper, we study two variational blind deblurring models for a single linage,The first model is to use the total variation prior in both image and blur, while the second model is to use the flame based prior in both image and blur. The main contribution of this paper is to show how to employ the generalized cross validation （GCV） method efficiently and automatically to estimate the two regularization parameters associated with the priors in these two blind motion deblurring models. Our experimental results show that the visual quality of restored images by the proposed method is very good, and they are competitive with the tested existing methods. We will also demonstrate the proposed method is also very efficient.

关键词： Blind deconvolution Iterative methods Total variation Framelet Generalizedcross validation.

Growth performance and scale insect infestation of Shorea leprosula in a common garden experimental plot

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Journal of Forestry Research 2023年第3期34卷 781-792页

作者： Chin Hong ng Kevin Kit Siong ng Soon Leong Lee Rempei Suwa Chai Ting Lee Lee Hong Tnah Forest Research Institute Malaysia 52109 KepongSelangorMalaysia Forestry Division Japan International Research Center for Agricultural SciencesTsukubaIbaraki 305‑8686Japan

Many tree planting programmes have long been initiated to increase forest cover to mitigate the effects of global climate *** planting requires careful planning at the project level,including using suitable species with favourable ***,there is a paucity of improvement data for tropical tree *** experimental common garden of Shorea leprosula was established to study traits related to growth performance which are key factors in planting *** of *** were collected from nine geographical forest *** study the effects of genetic variation,seedlings were planted in a common environment following a randomized complete block *** performance data collected 2017‒2019,one population showed the highest coefficient for relative height growth,significantly higher than most of the other ***,this population from Beserah also exhibited the lowest coefficient for scale insect *** study provides preliminary results on growth performance and susceptibility to scale insect infestation in *** and the first common garden experiment site conducted on dipterocarp *** lays a foundation for future genome-wide studies.

关键词： Root collar diameter Height Scale insect Relative growth rate Dipterocarp