检索结果-南通市图书馆

A novel strategy for gas mitigation during swine manure odour treatment using seaweed and a microbial consortium

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Environmental Science & Engineering 2020年第3期14卷 203-214页

作者： Madhavaraj Lavanya Ho-Dong Lim Kong-Min kim dae-Hyuk kim Balasubramani Ravindran Gui Hwan Han Center for Industrialization of Agricultural and Livestock Microorganisms(CIALM) Jeongeup-si 56212Republic of Korea Department of Molecular Biology Institute for Molecular Biology and GeneticsJeonbuk National UniversityJeonju 561-756Republic of Korea Department of Environmental Energy&Engineering Kyonggi UniversitySuwon-si 16227Republic of Korea

Gas emissions from swine farms have an impact on air quality in the Republic of *** manure stored in deep pits for a long time is a major source of harmful gas ***,we evaluated the mitigation of emissions of ammonia(N H 3),hydrogen sulfide(H2S)and amine gases from swine manure with biological products such as seaweed(Sargassum homeri)and a microbial consortium(Bacillus subtilis(1.2×10^9 CFU/mL),Thiobacillus sp.(1.0×10^10 CFU/mL)and Saccharomyces cerevisiae(2.0×10^9 CFU/mL))used as additives due to their promising benefits for nutrient ***,seaweed powder masking over two days provided notable control of over 98%-100%of the gas ***,significant control of gas emissions was especially pronounced when seaweed powder masking along with a microbial consortium was applied,resulting in a gas reduction rate of 100%for NH 3,amines and H2S over 10 days of *** results also suggested that seaweed powder masking and a microbial consortium used in combination to reduce the gas emissions from swine manure reduced odour compared with that observed when the two additives were used *** the consortium,seaweed decreased total volatile fatty acid(VFA)*** proposed novel method of masking with a microbial consortium is promising for mitigating hazardous gases,simple,and environmentally *** research is warranted to determine the mechanisms underlying the seaweed and substrate interactions.

关键词： Seaweed Consortium Mitigation Ammonia H2S Volatile fatty acids(VFAs)

Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第3期15卷 310-320页

作者： Chan Woo Cheon dae Hwan kim Dong Heon kim Yong Hoon Cho Jae Hun kim Department of Surgery School of MedicineMedical Research InstitutePusan National UniversityBusan 602-739South Korea

AIM:To determine the cytological and molecular effects of peroxisome proliferation-activated receptor(PPAR)-γ and PPAR-γ agonists on stomach cancer ***:To determine the proliferation-suppressive effects of troglitazone and ciglitazone,SNU-216 and SNU-668 stomach cancer cells were plated in media containing 40 μmol/L troglitazone and ciglitazone at a density of 1 × 104 cells/*** 3,5 and 7 d,the cells were counted with a *** assess the appearance of PPAR-γ,a reverse-transcription polymerase chain reaction analysis was *** day 7,Western blotting was used to determine the effects of troglitazone and ciglitazone on the expression of p21 and phosphorylated-ERK(pERK) *** cytometry analysis was used to determine which portion of the cell cycle was delayed when troglitazone was used to suppress cell *** order to clarify the mechanism underlying the activity of troglitazone,microarray analysis was ***:PPAR-γ was manifested in both SNU-216 and SNU-668 *** and troglitazone suppressed cell growth,and troglitazone was a stronger suppressor of stomach cancer cells than ciglitazone,an inducer of cell cycle arrest in the G1 ***-668 cells were also determined to be more sensitive to ciglitazone and troglitazone than SNU-216 *** troglitazone and ciglitazone were administered to stomach cancer cells,levels of p21 expression were increased,but ERK phosphorylation levels were *** GW9662,an antagonist of PPAR-γ,was applied in conjunction with ciglitazone and troglitazone,the cell growth suppression effect was *** gene transcription program revealed a variety of alterations as the consequence of troglitazone treatment,and multiple troglitazone-associated pathways were *** genes whose expression was increased by troglitazone treatment were associated with cell development,differentiation,signal transmission between cells,and cell adhesion,and were also associated

关键词：胃癌细胞增生活性分子效应

Stress and sleep quality in doctors working on-call shifts are associated with functional gastrointestinal disorders

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第18期23卷 3330-3337页

作者： Soo-Kyung Lim Seung Jin Yoo dae Lim Koo Chae A Park Han Jun Ryu Yong Jin Jung Ji Bong Jeong Byeong gwan kim Kook Lae Lee Seong-Joon Koh Department of Internal Medicine Seoul National University College of MedicineSeoul National University Boramae Hospital Department of Neurology Seoul National University Boramae HospitalSeoul National University College of Medicine

AIM To investigate the role of sleep quality and psychosocial problems as predictors of functional gastrointestinal disorders(FGIDs) in doctors that work 24 hour-on-call *** In this cross-sectional observation study, using the Rome Ⅲ Questionnaire and Pittsburgh Sleep Quality Index(PSQI), we analyzed 170 doctors with 24 houron-call shifts. RESULTS Among the participants that had experienced a 24 hour-on-call shift within the last 6 mo, 48(28.2%) had FGIDs. Overall prevalence of irritable bowel syndrome(IBS) and functional dyspepsia(FD) were 16.5% and 17.1%, respectively, with 5.3% exhibiting both. Sleep scores(PSQI)(8.79 ± 2.71 vs 7.30 ± 3.43, P = 0.008), the presence of serious psychosocial alarm(83.3%vs 56.6%, P = 0.004), and the proportion of doctors who experienced over two months of recent on-call work(81.2% vs 68.9%, P = 0.044) were significantly different between individuals with or without FGIDs. Multivariate analysis revealed that presenting serious psychosocial alarm was an independent risk factor for prevalence of FD(OR = 5.47, 95%CI: 1.06-28.15, P = 0.042) and poor sleep quality(PSQI ≥ 6) was a predictor of IBS(OR = 4.17, 95%CI: 1.92-19.02, P = 0.016). CONCLUSION Physicians should recognize the role of sleep impairment and psychological stress in the development of FGIDs and a comprehensive approach should be considered to manage patients with FGIDs.

关键词： Psychosocial 应力睡觉 24 hour-on-call 移动医生功能的胃肠的混乱

Is there a safe threshold for alcohol consumption in nonalcoholic fatty liver disease?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary Surgery and Nutrition 2020年第5期9卷 644-646页

作者： Mimi kim dae Won Jun Department of Radiology Hanyang University School of MedicineSeoulKorea Department of Internal Medicine Hanyang University School of MedicineSeoulKorea

Dose modest alcohol consumption(MAC)help the health care?There is a mainstream that MAC may not aggravate or even reduce cardiovascular disease and all-cause mortality(1,2).Light(≤3 drink/week)or moderate(>3 to≤14 drinks/week for men or>3 to≤7 drinks/week for women)alcohol consumption were reducing risk of mortality for all causes and cardiovascular disease(2).In 2018,combined analysis of 599,912 current drinkers in 83 prospective studies of high income countries,showed alcohol consumption was positive and curvilinear association with all-cause mortality and roughly linearly associated with a cardiovascular disease other than myocardial infarction(1).They recommend the threshold for lowest risk of all-cause mortality was 100 g/week.

关键词： mortality cardiovascular alcohol

Univector field method-based multi-agent navigation for pursuit problem in obstacle environments

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Central South University 2017年第4期24卷 1002-1012页

作者： Le Pham Tuyen Hoang Huu Viet Sang Hyeok An Seung gwan Lee Dong-Han kim Tae Choong Chung Department of Computer Science and Engineering Kyung Hee University Yongin Gyeonggi 446-701 Korea Department of Information Technology Vinh University 182-Le Duan Vinh City Nghe An 461056 Vietnam Humanitas College Kyung Hee University Yongin Gyeonggi 446-701 Korea Department of Electronics and Radio Engineering Kyung Hee University Yongin Gyeonggi 446-701 Korea

The pursuit problem is a well-known problem in computer science. In this problem, a group of predator agents attempt to capture a prey agent in an environment with various obstacle types, partial observation, and an infinite grid-world. Predator agents are applied algorithms that use the univector field method to reach the prey agent, strategies for avoiding obstacles and strategies for cooperation between predator agents. Obstacle avoidance strategies are generalized and presented through strategies called hitting and following boundary(HFB); trapped and following shortest path(TFSP); and predicted and following shortest path(PFSP). In terms of cooperation, cooperation strategies are employed to more quickly reach and capture the prey agent. Experimental results are shown to illustrate the efficiency of the method in the pursuit problem.

关键词： pursuit problem predator agent prey agent univector field method multi-agent systems

Formation of sub-100-nm suspended nanowires with various materials using thermally adjusted electrospun nanofibers as templates

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Microsystems & Nanoengineering 2023年第1期9卷 263-270页

作者： Yongkeun Oh dae-Sung Kwon Eunhwan Jo Yunsung Kang Sangjun Sim Jongbaeg kim School of Mechanical Engineering Yonsei UniversitySeoul03722Republic of Korea

The air suspension and location specification properties of nanowires are crucial factors for optimizing nanowires in electronic devices and suppressing undesirable interactions with *** various strategies have been proposed to fabricate suspended nanowires,placing a nanowire in desired microstructures without material constraints or high-temperature processes remains a *** this study,suspended nanowires were formed using a thermally aggregated electrospun polymer as a *** elaborately designed microstructure enables an electrospun fiber template to be formed at the desired location during thermal ***,the desired thickness of the nanowires is easily controlled with the electrospun fiber templates,resulting in the parallel formation of suspended nanowires that are less than 100 nm ***,this approach facilitates the formation of suspended nanowires with various *** is accomplished by evaporating various materials onto the electrospun fiber template and by removing the ***,copper,tungsten oxide(WO3),and tin oxide nanowires are formed as examples to demonstrate the advantage of this approach in terms of nanowire material ***(H2)and nitrogen dioxide(NO2)gas sensors comprising palladium and tungsten oxide,respectively,are demonstrated as exemplary devices of the proposed method.

关键词： nanowires template fibers

Assembly of charged aerosols on non-conducting substrates via ion-assisted aerosol lithography （IAAL）

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2017年第4期15卷 17-23页

作者： Seunghyon Kang Wooik Jung dae Seong kim Sei Jin Park Mansoo Choi School of Mechanical and Aerospace Engineering Seoul National University Seou 108826 Republic of Korea Global Frontier Center for Multiscale Energy Systems Seoul National University Seou108826 Republic of Korea

The development of ion-assisted aerosol lithography （IAAL） has enabled fabrication of complex three- dimensional nanoparticle （NP） structures on conducting substrates. In this work, the applicability of the IAAL technique was investigated on non-conducting substrates. The NP structure growth process on a non-conducting substrate was found to self-terminate and the structures subsequently repel incoming charged NPs and scatter them away. Electric field calculations supported the experimental findings and confirmed that the electric field distortions owing to charge build-up within the structures prevented additional NP deposition thereon. To regulate the charge build-up without compromising the number of NPs available for assembly, a corona discharger and an ion trap were implemented. By varying the number of ions available in the assembly process, an optimum level of ion injection was found that allowed for a prolonged （〉120 rain） assembly of NP structures on non-conducting substrates without the unwanted scattering of NPs.

关键词： Nanoparticle assembly Non-conducting substrate Ion-assisted aerosol lithography Ion trap

Evaluation of particle growth systems for sampling and analysis of atmospheric fine particles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2011年第6期9卷 606-610页

作者： dae Seong kim Sang Bum Hong Jung-Taek Kwon Kihong Park Department of Environmental Science and Engineering Gwangju Institute of Science and Technology Korea Polar Research Institute Laboratory of Toxicology College of Veterinary Medicine Seoul National University

Three types of water-based condensational growth systems, which can enable particles to grow in size to facilitate sampling and subsequent chemical analysis, were evaluated. The first one is a mixing type growth system where aerosols are mixed with saturated water vapor, the second one is a thermal diffusive growth system where warm flow enters cold-walled tube, and the third one is a laminar flow type where cold flow enters a warm wet-wall tube. Hygroscopic sodium chloride （NaCl）, ammonium sulfate （（NH4）2SO4） and ammonium nitrate （NH4N03）, and non-hygroscopic polystyrene latex （PSL） particles, in the size range of 50-400 nm, were used to determine their growth factors through the growth systems. Our data showed that the third-type growth system could enable particles to grow most efficiently regardless of their hygroscopic property. Collection efficiency of particles in the size range of 0.05-2.5 μm, in a continuous aerosol sampler after they passed through the third-type growth system was about 100%, suggesting that the third-type growth system would he the most useful among the tested growth systems for sampling and subsequent chemical analysis of fine and ultrafine particles.

关键词： Particle growth chamber Condensational growth Particle sampler Hygroscopic particles

Let-7 miRNA and CDK4 siRNA co-encapsulated in Herceptin-conjugated liposome for breast cancer stem cells

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Pharmaceutical Sciences 2020年第4期15卷 472-481页

作者： Jeong Hyun Shin dae Hwan Shin Jin Seok kim College of Pharmacy Sookmyung Women’s UniversitySeoul 04310Republic of Korea College of Pharmacy Chungbuk National UniversityCheongju 28160Republic of Korea

Recently,breast cancer stem cells(BCSCs)have rapidly emerged as a novel target for the therapy of breast cancer as they play critical roles in tumor growth,maintenance,metastasis,and ***-7 miRNA is known to be downregulated in a variety of cancers,especially BCSCs,whereas CDK4 being overexpressed in human epidermal growth factor receptor 2(HER-2)overexpressing tumor *** this study,let-7 miRNA and CDK4-specific siRNA were chosen as therapeutic agents and co-encapsulated in Herceptinconjugated cationic liposomes for breast cancer *** size,zeta potential,and encapsulation efficacy of mi/siRNA-loaded PEGylated liposome conjugated with Herceptin(Her-PEG-Lipo-mi/siRNA)were 176 nm,28.1 mV,and 99.7%±0.1%,*** cellular uptake(86%)was observed by fluorescence microscopy when SK-BR-3 cells were treated with Her-PEG-Lipo-mi/***,the increased amount of let-7a mRNA and decreased amount of cellular CDK4 mRNA were observed by qRT-PCR when SK-BR-3 cells were treated with Her-PEG-Lipo-mi/siRNA,which was even more so when SK-BR-3 stem cells were used(197 vs 768 times increase for let-7a,62%vs 68%decrease for CDK4).Growth inhibition(65%)andmigration arrest(0.5%)of the cellswere achieved by the treatment of the cells with Her-PEG-Lipo-mi/siRNA,but not withmi/siRNA complex or other *** conclusion,an efficient liposomal delivery system for the combination of miRNA and siRNA to target the BCSCs was developed and could be used as an efficacious therapeuticmodality for breast cancer.

关键词： Let-7 miRNA CDK4 siRNA Liposomes Breast cancer stem cells