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Unconventional Hall effect induced by Berry curvature

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National Science Review 2020年第12期7卷 1879-1885页

作者： Jun Ge da Ma Yanzhao Liu Huichao Wang Yanan Li Jiawei Luo Tianchuang Luo Ying Xing Jiaqiang Yan david Mandrus Haiwen Liu X.c.Xie Jian Wang International center for Quantum Materials School of PhysicsPeking University department of Applied Physics The Hong Kong Polytechnic University department of Physics Pennsylvania State UniversityUniversity Park department of Materials Science and Engineering School of New Energy and MaterialsChina University of Petroleum department of Materials Science and Engineering University of Tennessee Materials Science and Technology Division Oak Ridge National Laboratory center for Advanced Quantum Studies Department of PhysicsBeijing Normal University cAS center for Excellence in Topological Quantum computation University of Chinese Academy of Sciences Beijing Academy of Quantum Information Sciences collaborative Innovation center of Quantum Matter

Berry phase and Berry curvature play a key role in the development of topology in physics and do contribute to the transport properties in solid state *** this paper,we report the finding of novel nonzero Hall effect in topological material zr Te5 flakes when the in-plane magnetic field is parallel and perpendicular to the ***,both symmetric and antisymmetric components with respect to magnetic field are detected in the in-plane Hall *** theoretical analysis suggests that the magnetotransport properties originate from the anomalous velocity induced by Berry curvature in a tilted Weyl *** work not only enriches the Hall family but also provides new insights into the Berry phase effect in topological materials.

关键词： Berry curvature topological material Hall effect tilted Weyl semimetal Berry phase effect

Hypercholesterolemia,low density lipoprotein receptor and proprotein convertase subtilisin/kexin-type 9

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The Journal of Biomedical Research 2015年第5期29卷 356-361页

作者： Hong-mei Gu da-wei zhang departments of Pediatrics and Biochemistry Group on the Molecular and Cell Biology of LipidsUniversity of Alberta

Atherosclerotic cardiovascular disease is the main cause of mortality and morbidity in the world. Plasma levels of low density lipoprotein cholesterol （LDL-c） are positively correlated with the risk of atherosclerosis. High plasma LDL concentrations in patients with hypercholesterolemia lead to build-up of LDL in the inner walls of the arteries, which becomes oxidized and promotes the formation of foam cells, consequently initiating atherosclerosis. Plasma LDL is mainly cleared through the LDL receptor （LDLR） pathway. Mutations in the LDLR cause familiar hyperch- olesterolemia and increase the risk of premature coronary heart disease. The expression of LDLR is regulated at the transcriptional level via the sterol regulatory element binding protein 2 （SREBP-2） and at the posttranslational levels mainly through proprotein convertase subtilisin/kexin-type 9 （PcSK9） and inducible degrader of the LDLR （IDOL）. In this review, we summarize the latest advances in the studies of PcSK9.

关键词： hypercholesterolemia low density lipoprotein receptor statin atherosclerosis proprotein convertasesubtilisin/kexin -type 9

Four New Isovalertatins M33, D13, D33, and D43, from the culture Filtrate of Streptomyces luteogriseus

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chinese chemical Letters 2006年第3期17卷 351-354页

作者： Duan Yun SI da Fang zHONG chang Xiao LIU Tianjin State Key Laboratory of Pharmacokinetics and Pharmacodynamics Tianjin Institute of Pharmaceutical Research Tianjin 300193 center for Drug Metabolism Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203

Four new aminooligosaccharides, isovalertatins M33 1, D13 2, D33 3, and D43 4, were isolated from the culture filtrate of Streptomyces luteogriseus. Their structures were established by chemical and spectroscopic evidences including ESI multistage mass spectrometry and 2- dimensional NMR techniques, and were found in full consistencies with the previous profiling results proposed by Lc/ESI/MS analysis.

关键词： Streptomyces luteogriseus aminooligosaccharide isovalertatins metabolomics

Hepatitis D infection:from initial discovery to current investigational therapies

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gastroenterology Report 2019年第4期7卷 231-245,I0001页

作者： Ben L.da Theo Heller christopher Koh Digestive Diseases Branch National Institute of Diabetes&Digestive&Kidney DiseasesNational Institutes of HealthBethesdaMDUSA Liver Diseases Branch National Institute of Diabetes&Digestive&Kidney DiseasesNational Institutes of HealthBethesdaMDUSA

Hepatitis D is the most severe form of viral hepatitis associated with a more rapid progression to cirrhosis and an increased risk of hepatocellular carcinoma and mortality compared with hepatitis B *** once thought of as a disappearing disease,hepatitis D is now becoming recognized as a serious worldwide issue due to improvement in diagnostic testing and immigration from endemic *** these concerns,there is currently only one accepted medical therapy(pegylated-interferon-a)for the treatment of hepatitis D with less than desirable efficacy and significant side *** to these reasons,many patients never undergo ***,increasing knowledge about the virus and its life cycle has led to the clinical development of multiple promising new therapies that hope to alter the natural history of this disease and improve patient *** this article,we will review the literature from discovery to the current investigational therapies.

关键词： Hepatitis D hepatitis B epidemiology natural history outcome treatment novel therapies

FATIGUE cRAcK GROWTH FEATURE OF Fe-cr-Ni MATRIX cOMPOSITE REINFORcED BY TITANIUM cARBIde PARTIcULATE AT 1023K

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Acta Metallurgica Sinica(English Letters) 1999年第6期12卷 0-0,0-0+0-0页

作者： z. F. Wan X.D. Hui G.Q. Yuan Y. S. Yang X.c chen Shandong University of Technology Jinan 250061 China Institute of Metal Research The Chinese Academy of Sciences Shenyang 110015 China Institute of Physics The Chinese Academy of Sciences Beijing 100080 China

The initiation and propagation of the short fatigue crack in a 10vol% titanium carbide particulate reichreed cast Fe-26cr-14Ni mathe coopsite at 1023K were *** is shown that the titanium carbide particulate may hinder the crack propagation and fatigue fracture of the composite. The relationships between fatigue crack propagation rate and stress intensity factor are da/dN=4.2×10-c(△K)4 for the matrix alloy and da/dN=1.4×10-19(△K)c for the composite. The fatigue thresholds of the composite and mathe alloy are 78 and 3.2MPa.m1/2, respectively. Microcracks initiate at the intedece between titanium carbide particulate and austenite and then propagate in carkide particles. The fracture sudece of the composite shows a distinct transition from wavy and serated cleavage near the threshold regime to striation-type splitting in the stable fatigue crack propagation stage and to a veined morphology characteristic in unstable rapid region.

关键词： fatigue crack initiation and propagation Fe-cr-Ni matrix composite titanium carbide particulate

description of the Rigid Triaxial deformation at Low Energy in 76Ge with the Proton-Neutron Interacting Model IBM2

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chinese Physics Letters 2013年第12期30卷 21-24页

作者： zHANG da-Li DING Bin-gang department of Physics Huzhou Teacher's CollegeHuzhou 313000

We investigate properties of the low-lying energy states for 76Ge within the framework of the proton-neutron interacting model IBM2,considering the validity of the z=38 subshell closure 88Sr50 as a doubly magic *** introducing the quadrupole interactions among like bosons to the IBM2 Hamiltonian,the energy levels for both the ground state andγbands are reproduced ***,the doublet structure of theγband and the energy staggering signature fit the experimental data *** ratios of B(E2)transition strengths for some states of theγband,and the g factors of the 2^(+)_(1),2^(+)_(2) states are very close to the experimental *** calculation result indicates that the nucleus exhibiting rigid triaxial deformation in the low-lying states can be described rather well by the IBM2.

关键词： IBM2 states closure

Synthesis and crystal Structure of 2-Amino-5,6-dihydro-4-(3,4-dimethoxyphenyl)-4H-benzo[h]chromene-3-carbonitrile

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chinese Journal of Structural chemistry 2006年第7期25卷 775-778页

作者： zHUANG Qi-Ya WU Nan SHI da-Qing TU Shu-Jiang department of chemistry Xuzhou Normal University Xuzhou 221116 China Key Laboratory of Biotechnology on Medical Plants of Jiangsu Province Xuzhou 221116 China

The title compound 2-amino-5,6-dihydro-4-（3,4-dimethoxyphenyl）-4H-benzo[h]- chromene-3-carbonitrile （c22H20N2O3, Mr = 360.40） was obtained by the reaction of 2-（3,4-dimeth- oxybenzylidene）-1-tetralone and malononitrile in DMF in the presence of KF-montmorillonite. Its structure was confirmed by IR and ^1H NMR spectra. The crystal is of monoclinic, space group c2/c with a = 24.101（6）, b = 9.146（2）, c = 17.238（3） ,A, β= 95.92（2）°, z = 8, V= 3779.4（14） ,A^3, Dc = 1.267 g/cm^3, μ（MoKa） = 0.085 mm^-1, F（000） = 1520, R = 0.0409 and wR = 0.0981 for 2043 observed reflections （I 〉 2σ（I））.

关键词： KF-montmorillonite 2-aminochromene crystal structure synthesis

Blue Luminescent zinc(II)-and cadmium(II)-1,4-phenylenediacetate complexes

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chinese Journal of Structural chemistry 2006年第10期25卷 1161-1166页

作者： XU Yan-Qing zHOU You-Fu YUAN da-Qiang HONG Mao-chun State Key Laboratory of Structural chemistry Fujian Institute of Research on the Structure of Matter The Chinese Academy of Sciences Fuzhou Fujian 350002 China

Two mixed-ligand polymeric complexes formulated as {[zn（pda）（bpy）]·0.5H2O}n （pda = 1,4-phenylenediacetate, bpy = 2,2＇-bipyridine） 1 and {[cd（pda）（bpy）]·1.5H2O}n 2 have been hydrothermally synthesized. Single-crystal X-ray diffraction analyses reveal that the structures of complexes 1 and 2 possess similar one-dimensional zigzag chains. crystal data for compound 1： monoclinic, space group P21/c, a = 15.965（2）, b = 8.305（1）, c= 14.856（2） °A, β= 111.048（2）°, Mr = 422.73, V = 1838.2（4）°A^3, z = 4, Dc = 1.528 g/cm^3, μ= 1.368 mm^-1, F（000） = 868, the final R = 0.0783 and wR = 0.1469 （w =1/[σ^2（Fo^2）＋（0.0351P）^2＋ 8.0014P], where P = （Fo^2 ＋ 2Fc^2）/3） based on 2025 observed reflections with I〉 2σ（I）; and those for compound 2： monoclinic, space group c2/c, a = 29.921 （7）, b = 8.5400（17）, c = 15.320（3） °A,β= 99.59（3）°, Mr = 487.75, V = 3859.9（14） °A^3, z = 8, Dc = 1.668 g/cm^3, μ= 1.169 mm^-1, F（000） = 1936, the final R = 0.0723 and wR = 0.1612 （w = 1/[σ^2（Fo^2）＋（0.0681P）^2 ＋ 55.9577P], where P = （Fo^2 ＋ 2Fc^2）/3） based on 2130 observed reflections with I〉 2σ（I）. Fluorescent analyses show that both complexes exhibit intense blue luminescence （λmax = 485 nm for 1 and 475 nm for 2） upon excitation at 330 nm.

关键词： zinc(Ⅱ) cadmium(Ⅱ) crystal structure,coordination polymer fluorescence

clinicopathological significance of B-cell-specific Moloney murine leukemia virus insertion site 1 expression in gastric carcinoma and its precancerous lesion

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World Journal of gastroenterology 2009年第17期15卷 2145-2150页

作者： Jing zhao Xiang-Dong Luo chun-Li da Yan Xin The Fourth Laboratory of cancer Institute Department of Tumor Pathology of General Surgery Institute First Affiliated Hospital of China Medical University Shenyang 110001 Liaoning Province China

AIM： To explore the relation between B-cell-specific Moloney murine leukemia virus insertion site 1 （Bmi-1） expression and the clinicopathological features of gastric carcinoma （Gc）.METHODS： Immunohistochemistry was used to detect the expression of Bmi-1 and ki-67. Doublelabeling staining was used to display the distribution of Bcl-2^＋/ki-67 cells in 162 cases of Gc and its matched normal mucosa and precancerous ***： The positive rate of Bmi-1 expression in Gc（52.5%） was significantly higher than that in normal gastric mucosa （21.6%, X^2 = 33.088, P 〈 0.05）. The Bmi-1 expression in Gc was closely related with the Lauren＇s and Borrmann＇s classification and clinicalstage （X^2 = 4.400, 6.122 and 11.190, respectively, P〈 0.05）. The expression of ki-67 was related to the Borrmann＇s classification （X^2 = 13.380, P 〈 0.05）.Bcl-2 expression was correlated with the Lauren＇s classification （z2 = 4.725, P 〈 0.05）, and the Bmi-1 expression both in Gc （rk = 0.157, P 〈 0.05） and inintestinal metaplasia （rk = 0.270, P 〈 0.05）.cONcLUSION： Abnormal Bmi-1 expression in Gcmay be involved in cell proliferation, apoptosis andcancerization. This marker can objectively indicate theclinicopathological characteristics of Gc.

关键词： B-cell-specific Moloney murine leukemiavirus insertion site 1 gastric carcinoma Precancerouslesion cell proliferation Apoptosis