Synthesis and Crystal Structure of 2-Amino-5,6-dihydro-4-(3,4-dimethoxyphenyl)-4H-benzo[h]chromene-3-carbonitrile

作     者：ZHUANG Qi-Ya WU Nan SHI Da-Qing TU Shu-Jiang 

作者机构：Department of Chemistry Xuzhou Normal University Xuzhou 221116 China Key Laboratory of Biotechnology on Medical Plants of Jiangsu Province Xuzhou 221116 China 

出 版 物：《Chinese Journal of Structural Chemistry》 (结构化学（英文）)

年 卷 期：2006年第25卷第7期

页      面：775-778页

核心收录：

学科分类：07[理学] 

基　　金：Financially supported by the "Surpassing Project" Foundation of Jiangsu Province (No. QL9801) and Project of Scientific Research of Xuzhou Normal University (NO. 04XLA03) 

主　　题：KF-montmorillonite 2-aminochromene crystal structure synthesis 

摘      要：The title compound 2-amino-5,6-dihydro-4-（3,4-dimethoxyphenyl）-4H-benzo[h]- chromene-3-carbonitrile （C22H20N2O3, Mr = 360.40） was obtained by the reaction of 2-（3,4-dimeth- oxybenzylidene）-1-tetralone and malononitrile in DMF in the presence of KF-montmorillonite. Its structure was confirmed by IR and ^1H NMR spectra. The crystal is of monoclinic, space group C2/c with a = 24.101（6）, b = 9.146（2）, c = 17.238（3） ,A, β= 95.92（2）°, Z = 8, V= 3779.4（14） ,A^3, Dc = 1.267 g/cm^3, μ（MoKa） = 0.085 mm^-1, F（000） = 1520, R = 0.0409 and wR = 0.0981 for 2043 observed reflections （I 〉 2σ（I））.