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The chromosome-based lavender genome provides new in sights into Lamiaceae evolution and terpenoid biosynthesis

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Horticulture Research 2021年第1期8卷 523-536页

作者： Jingrui Li Yiming Wang yanmei dong Wenying Zhang Di Wang Hongtong Bai Kui Li Hui Li Lei Shi Key Laboratory of Plant Resources and Beijing Botanical Garden Institute of BotanyChinese Academy of SciencesXiangshan 100093 BeijingChina University of Chinese Academy of Sciences 100015 BeijingChina Novogene Bioinformatics Institute 100083 BeijingChina

The aromatic shrub Lavandula angustifolia produces various volatile terpenoids that serve as resources for essential oils and function in plant-insect *** better understand the genetic basis of the terpenoid diversity in lavender,we present a high-quality reference genome for the Chinese lavender cultivar‘Jingxun 2'using PacBio and Hi-C technologies to anchor the 894.50 Mb genome assembly into 27 *** addition to the y triplication event,lavender underwent two rounds of whole-genome duplication(WGD)during the Eocene-Oligocene(29.6 MYA)and Miocene-Pliocene(6.9 MYA)*** a result of tandem duplications and lineage-specific WGDs,gene families related to terpenoid biosynthesis in lavender are substantially expanded compared to those of five other species in *** terpenoid biosynthesis transcripts are abundant in glandular *** further integrated the contents of ecologically functional terpenoids and coexpressed terpenoid biosynthetic genes to construct terpenoid-gene *** gene clusters,including TPS-TPS,TPS-CYP450,and TPS-BAHD,linked with compounds that primarily function as attractants or repellents,were identified by their similar patterns of change during flower development or in response to methyl *** analysis of the genetic basis of the production of volatiles in lavender could serve as a foundation for future research into lavender evolution,phytochemistry,and ecology.

关键词： function expanded transitions

Exploring the links between gut microbiome changes and irritable bowel syndrome in Han populations in the Tibetan Plateau

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2023年第9期24卷 823-838页

作者： Xingguang ZHANG Wei XU Weilong ZHONG Wencheng ZHANG Cheng YANG Lisa DUAN Haiyan NIU yanmei dong Taotao LIU Shihai XIA Bangmao WANG Department of Gastroenterology and Hepatology Tianjin Medical University General HospitalTianjin Institute of Digestive DiseasesTianjin Key Laboratory of Digestive DiseasesTianjin300052China Department of Gastroenterology Characteristic Medical Center of Chinese People’s Armed Police ForceTianjin Key Laboratory of Hepatopancreatic Fiberosis and Molecular Diagnosis&TreatmentTianjin300162China

The gut microbiome shows changes under a plateau environment,while the disbalance of intestinal microbiota plays an important role in the pathogenesis of irritable bowel syndrome(IBS);however,the relationship between the two remains *** this work,we followed up a healthy cohort for up to a year before and after living in a plateau environment and performed 16S ribosomal RNA(rRNA)sequencing analysis of their fecal *** evaluating the participants’clinical symptoms,combined with an IBS questionnaire,we screened the IBS sub-population in our *** sequencing results showed that a high-altitude environment could lead to changes in the diversity and composition of gut *** addition,we found that the longer the time volunteers spent in the plateau environment,the more similar their gut microbiota composition and abundance became compared to those before entering the plateau,and IBS symptoms were significantly ***,we speculated that the plateau may be a special environment that induces *** taxonomic units g_Alistipes,g_Oscillospira,and s_Ruminococcus_torques,which had been proved to play important roles in IBS pathogenesis,were also abundant in the IBS cohort at high ***,the disbalance of gut microbiota induced by the plateau environment contributed to the high frequency of IBS and the psychosocial abnormalities associated with *** results prompt further research to elucidate the relevant mechanism.

关键词： Gut microbiome Plateau environment Irritable bowel syndrome

Effect of Cyclocarya paliurus polysaccharides on streptozotocin-induced diabetic nephropathy in rats

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Journal of Traditional Chinese Medicine 2020年第6期40卷 956-964页

作者： Xia Xichao Mao dongxue Dai Hongmei Wu Xi Zhang Zuyuan Wang Huaying Zhou Wenwen dong yanmei Wang Mengqi Li Yuan Shao Xiangyang Ouyang Jingfeng Medical College Pingdingshan UniversityPingdingshan 467000China Beijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment for Major Diseases Experimental Research CenterChina Academy of Chinese Medical SciencesBeijing 100700China

OBJEVTIVE:To investigate the efficacy of Cyclocarya paliurus(***)polysaccharides on streptozotocin-induced diabetic nephropathy in ***:Rats were divided into 6 groups,including group of normal control,group of diabetic control,group of metformin treatment,low-dose group of *** polysaccharides treatment,middle-dose group of *** polysaccharides treatment and high-dose group of *** polysaccharides *** analysis of kidney was analyzed using hematoxilin and *** of blood glucose,creatinine,urea,uric acid were determined by ***-oxidative enzymes were measured by real-time polymerase chain reaction(PCR)and enzyme-linked immunosorbent assay(ELISA).Advanced glycation end products(AGEs)and transforming growth factor-β1(TGF-β1)level was measured by ***:Abnormal changes were observed in the group of diabetic control characterized by atrophy of the renal glomeruli with hypercellularity,congestion of glomerular tufts,dilation of the renal spaces,and degeneration of renal *** with that of normal group,blood glucose,creatinine,urea,uric acid level was significantly increased in the group of diabetic *** dismutase,catalase,glutathione peroxidase,glutathione reductase level was significantly decreased,but AGEs and TGF-β1 level was significantly *** contrast,administration of *** polysaccharides and metformin could reverse the above-mentioned results of the group of diabetic control,especially in the high-dose group of *** ***:Our findings suggest that *** polysaccharides may play a protecting role for nephropathy of diabetic rats by lowering glucose,creatinine,urea,uric acid level,enhancing the antioxidative ability,and reducing AGEs and TGF-β1 expression.

关键词： Diabetic nephropathies Cyclocarya paliurus Polysaccharides Antioxidatnts Glycation end products advanced Transforming growth factor beta1

Compositional change in human enamel irradiated with MIR free electron laser

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Chinese Science Bulletin 2001年第23期46卷 2016-2018页

作者： LIU Nianqing LI Yonggui ZHU Junbiao ZHANG Liwen WANG Mingkai WU Gang YANG Xueping Li Guangcheng Huang Yuying dong yanmei GAO Xuejun Institute of High Energy Physics Chinese Academy of SciencesBeijing 100039China Stomatological College Peking UniversityBeijing 100081China 不详

The purpose of this study was to investigate compositional changes in human enamel irradiated with the free electron laser (FEL). The exposure on dental enamel at the wavelength of 9.64 μm was observed with the Beijing free electron laser. The distribution of elements in the irradiated or non-irradiated enamel was measured by scanning electron microscope (SEM) with energy-dispersive spectroscopy and synchrotron radiation X-ray fluorescence (SRXRF) in Beijing Synchrotron Radiation Facility (BSRF). The results showed that the P/Ca ratio in the ablation region of enamel at the maximum wavelength of infrared absorption was obviously smaller than that at the non-maximum wavelength. In the ablation region the ratios of P/Ca and Ca/Sr were smaller than those in the non-ablation region. The distributions of P, Ca and Sr in the ablation region were heterogeneous due to the element change caused by FEL irradiation.

关键词： human enamel Beijing free electron laser synchrotron radiation X-ray fluorescence ablation element distribution.

美国先前学习学分的获取路径、实施现状及启示

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职业技术教育 2015年第6期36卷 17-26页

作者：董衍美吉林省人文社会科学重点研究基地吉林工程技术师范学院职业技术教育研究院

美国在先前学习成果的认证和转换方面发展相对成熟,其先前学习学分的获取路径主要有DANTES学科标准化测试、大学水平考试、伊克塞尔希学院的测试、学历档案评估、军事培训项目等。目前,美国学生和高校对成人先前学习学分的认可度都较高... 详细信息

美国在先前学习成果的认证和转换方面发展相对成熟,其先前学习学分的获取路径主要有DANTES学科标准化测试、大学水平考试、伊克塞尔希学院的测试、学历档案评估、军事培训项目等。目前,美国学生和高校对成人先前学习学分的认可度都较高。但同时也存在部分高校和企业不认可ACE的推荐学分;学生进行先前学习评估的过程中缺乏清晰的具有一贯性的信息指导,很难选择恰当的学分转入院校等问题。因此,我国要构建学习成果积累与转换体系,可从以下方面着手:各级政府要为学分转换的实施提供保障;建立全国考试中心;建立全国性的教育质量认证机构;建立各级各类机构的学分转换信息服务平台;建立学分互换的教育机构联盟。

关键词：美国先前学习学分路径认可度

十八大以来中国特色现代职业教育人才培养质量工作报告

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职业技术教育 2017年第24期38卷 53-59页

作者：王哲董衍美吉林工程技术师范学院职业技术教育研究院吉林工程技术师范学院

提高人才培养质量是加快发展现代职业教育的核心任务。党的十八大以来,全国职业教育战线从推进人才培养模式改革、建立健全课程衔接体系、建设"双师型"教师队伍、提高信息化水平、加强国际交流与合作5个方面加快贯彻落实习总书记提出的... 详细信息

提高人才培养质量是加快发展现代职业教育的核心任务。党的十八大以来,全国职业教育战线从推进人才培养模式改革、建立健全课程衔接体系、建设"双师型"教师队伍、提高信息化水平、加强国际交流与合作5个方面加快贯彻落实习总书记提出的"着力提高人才培养质量"的要求。考察职业教育人才培养质量的工作成效,可以从观念变革、实践经验和人才产出3个视角看:从观念变革的视角看,新的人才培养质量观已经成为共识而深入人心并为国际社会所理解和欣赏;从实践经验的视角看,职业教育人才培养模式加快走向成熟化和多样化;从人才产出的视角看,职业学校毕业生成为支撑现代化建设的生力军。

关键词：职业教育人才培养质量高素质劳动者技术技能人才

UNESCO政策框架下我国成人教育发展研究

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职业技术教育 2016年第21期37卷 18-26页

作者：董衍美董衍勇吉林工程技术师范学院职业技术教育研究院临沂临港经济开发区第五中学

通过对UNESCO两次发布的关于成人教育的《建议书》以及我国《教育规划纲要》中关于成人教育的规定进行比较分析,发现:成人教育在终身学习体系中的地位越来越重要,其不仅关系到全民学习、终身学习的需求满足,而且影响经济社会和劳动力市... 详细信息

通过对UNESCO两次发布的关于成人教育的《建议书》以及我国《教育规划纲要》中关于成人教育的规定进行比较分析,发现:成人教育在终身学习体系中的地位越来越重要,其不仅关系到全民学习、终身学习的需求满足,而且影响经济社会和劳动力市场的发展,应从如下方面大力发展成人教育,强化人力资源能力建设,加速由人力资源大国向强国转变:加速立法和政策颁布;建立政府统筹、多元参与、共建共享的成人教育管理体制机制;建立健全成人教育利益攸关方的费用分担机制、并出台奖励措施,调动所有利益攸关方的参与积极性;提供包容、公平、优质的成人学习与教育机会,让人人成为具有国际竞争力的、负责任的高素质公民;加强监管和评价机制,确保和提升成人教育质量。

关键词： UNESCO 成人教育成人学习与教育终身学习政策框架

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服务“一带一路”战略的实践探索

职业技术教育 2015年第30期36卷 22-24页

作者：李瑶董衍美吉林省人文社会科学重点研究基地吉林工程技术师范学院职业技术教育研究院东北师范大学文学院

当前,"一带一路"建设已成为促进沿线各国经济繁荣与区域合作的世纪性伟业。作为贯彻国家"走出去"战略的先锋,中国企业正在全面深度参与"一带一路"战略的实施,同时职业教育也正在为此大战略积极供献自己的力量。在此过程中,一些企业和职... 详细信息

当前,"一带一路"建设已成为促进沿线各国经济繁荣与区域合作的世纪性伟业。作为贯彻国家"走出去"战略的先锋,中国企业正在全面深度参与"一带一路"战略的实施,同时职业教育也正在为此大战略积极供献自己的力量。在此过程中,一些企业和职业院校在强化人才支撑服务"一带一路"方面进行了有益的尝试,形成了许多有创新、有突破、有成效的成功做法。

关键词：一带一路职业教育企业走出去

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新时代职业教育发展作为论

职业技术教育 2017年第33期38卷 23-26页

作者：程宇董衍美吉林省职教研究中心吉林工程技术师范学院职业技术教育研究院吉林大学经济学院吉林工程技术师范学院

中国特色社会主义进入新时代,党和国家也赋予了中国特色职业教育新的目标和要求。贯彻落实党的十九大精神,回应经济社会发展和人民群众对新时代职业教育的新期待,瞄准2030,展望2050,中国职业教育应在完善职业教育和培训体系、推进治理... 详细信息

中国特色社会主义进入新时代,党和国家也赋予了中国特色职业教育新的目标和要求。贯彻落实党的十九大精神,回应经济社会发展和人民群众对新时代职业教育的新期待,瞄准2030,展望2050,中国职业教育应在完善职业教育和培训体系、推进治理体系和治理能力现代化、提高人才培养质量和创新能力、夯实职业教育发展基础、增强服务国家战略的能力、扩大职业教育的对外开放与合作交流等方面有所作为。

关键词：十九大新时代新作为职业教育