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基于康普顿伽玛光-核共振荧光的冰毒无损检测的Geant4模拟（英文）

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基于康普顿伽玛光-核共振荧光的冰毒无损检测的Geant4模拟（英文）

Current status and highlights of the ElI-NP research program

第十九届全国核电子学与核探测技术学术年会

作者：蓝浩洋黄兴德赵盛强周剑良朱志超徐毅 d.l.balabanski 罗文南华大学核科学技术学院 Extreme light Infrastructure-Nuclear Physics

核共振荧光(NRF)技术是鉴别物质中核素成分的有力工具。激光康普顿散射(lCS)伽玛光源具有能量可调、准直性好、强度高等优点,非常适用于核共振荧光技术研究。本文提出了一种基于康普顿伽玛光-核共振荧光的冰毒(CHN)无损检测技术。理论分... 详细信息

核共振荧光(NRF)技术是鉴别物质中核素成分的有力工具。激光康普顿散射(lCS)伽玛光源具有能量可调、准直性好、强度高等优点,非常适用于核共振荧光技术研究。本文提出了一种基于康普顿伽玛光-核共振荧光的冰毒(CHN)无损检测技术。理论分析lCS伽玛光-核共振荧光过程,计算冰毒中C、N的NRF反应截面、退激宽度、退激光子散射角等参数,获得NRF产额与核素比。结果表明,C和N从基态分别跃迁至激发态(2,4438 keV)和(0,4915 keV)时有较大的共振反应截面;前者在入射光的垂直方向有较强的退激辐射,而后者的退激辐射为各向同性分布。研究开发一套激光康普顿伽玛光-核共振荧光模拟程序G4NRF,模拟入射能量为0至5MeV的lCS光源与冰毒靶的相互作用过程和退激辐射的探测过程,获得C和N的NRFγ能谱分布以及核素含量比N/N=0.11,与理论值高度吻合。本研究工作为基于国际高强度lCS光源装置(譬如欧洲极端光基础设施-核物理和中国上海激光电子伽玛源)开展特殊核材料的NRF无损检测实验提供技术方案。

关键词：核共振荧光康普顿伽玛光无损检测

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Matter and Radiation at Extremes 2020年第2期5卷 2-25页

作者： K.A.Tanaka K.M.Spohr d.l.balabanski S.Balascuta l.Capponi M.O.Cernaianu M.Cuciuc A.Cucoanes I.dancus A.dhal B.diaconescu d.doria P.Ghenuche d.G.Ghita S.Kisyov V.Nastasa J.F.Ong F.Rotaru d.Sangwan P.-A.Soderstrom d.Stutman G.Suliman O.Tesileanu l.Tudor N.Tsoneva C.A.Ur d.Ursescu N.V.Zamfir Extreme light Infrastructure(ElI-NP)and Horia Hulubei National Institute for R&din Physics and Nuclear Engineering(IFIN-HH) Str.Reactorului No.30077125 Bucharest–M˘agureleRomania Johns Hopkins University 3400 N.Charles StreetBaltimoreMaryland 21218USA

The emergence of a new era reaching beyond current state-of-the-art ultrashort and ultraintense laser technology has been enabled by the approval of around V 850 million worth of structural funds in 2011–2012 by the European Commission for the installation of Extreme light Infrastructure(ElI).The ElI project consists of three pillars being built in the Czech Republic,Hungary,and *** challenging proposal is based on recent technical progress allowing ultraintense laser fields in which intensities will soon be reaching as high as I0∼1023Wcm−*** tremendous technological advance has been brought about by the invention of chirped pulse amplification by Mourou and *** is hosting the ElI for Nuclear Physics(ElI-NP)pillar in M˘agurele near *** new facility,currently under construction,is intended to serve the broad national,European,and international scientific *** mission covers scientific research at the frontier of knowledge involving two *** first is laser-driven experiments related to NP,strong-field quantum electrodynamics,and associated vacuum *** second research domain is based on the establishment of a Compton-backscattering-based,high-brilliance,and intenseγbeam with Eγ≲19.5 MeV,which represents a merger between laser and accelerator *** system will allow the investigation of the nuclear structure of selected isotopes and nuclear reactions of relevance,for example,to astrophysics with hitherto unprecedented resolution and *** addition to fundamental themes,a large number of applications with significant societal impact will be *** implementation of the project started in January 2013 and is spearheaded by the ElI-NP/Horia Hulubei National Institute for Physics and Nuclear Engineering(IFIN-HH).Experiments will begin in early 2020.

关键词： intense frontier approval

238U(~9Be,5n)242Cm绝对激发函数测量(英文)

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IMP & HIRFl Annual Report 2009年 41-41页

作者：滑伟 G.Georgiev G.de France d.l.balabanski Centre de Spectrométrie Nucléaire et de Spectrométrie de Masse 2. GANIl 3. INRNE Bulgarian Academy of Sciences

A cross-section measurement for the 238U(9Be,5n)242Cm reaction was carried out in IMP as a collaborative project with *** theoretical calculations of the reaction cross-section using different codes differ by a factor...

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Anti-amyloid antibodies in Alzheimer’s disease: what did clinical trials teach us?

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Neural Regeneration Research 2025年第4期20卷 1092-1093页

作者： danko Jeremic lydia Jiménez-díaz Juan d.Navarro-lópez NeuroPhysiology&Behavior lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s disease(Ad)may exist,both the original amyloid cascade and tau hypotheses posit that abnormal misfolding and accumulation of amyloid-β(Aβ)and tau protein is the central event causing the ***,that conclusion could be only partly true,and there is conflicting evidence about the role of both proteins in Ad,being able to precede and influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand tau proteins may be independently involved in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evidence suggests that Aβand tau act synergistically,rather than additively in disease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer additive

A data-based photonuclear simulation algorithm for determining specific activity of medical radioisotopes

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Nuclear Science and Techniques 2016年第5期27卷 160-167页

作者： Wen luo dimiter l.balabanski dan Filipescu School of Nuclear Science and Technology University of South ChinaHengyang 421001China Extreme light Infrastructure-Nuclear Physics(ElI-NP)/"Horia Hulubei"National Institute for R&d in Physics and Nuclear Engineering(IFIN-HH) 30 Reactorului St.Bucharest-Magurelejud.IlfovP.O.B.MG-6077125 IasiRomania

For simulating more accurately neutron or proton production from photonuclear reactions,a data-based photonuclear reaction simulation algorithm has been *** photonuclear cross sections from evaluated or experimental database are chosen as input *** checking the validity of the use of the data-based photonuclear algorithm,benchmarking simulations are presented in *** calculate photonuclear cross sections or reaction yield for ~9Be,^(48)Ti,^(133)Cs,and ^(197)Au and compare them with experimental data in the region of incident photon energy below ~30 *** Geant4 can hardly reproduce photonuclear experimental data,results obtained from the data-based photonuclear algorithm are found in good agreement with experimental *** application in estimation of specific activity of radioisotopes is further *** conclude that the developed data-based photonuclear algorithm is suitable for an accurate prediction of photoninduced neutron or proton productions.

关键词：放射性同位素模拟算法医用光核反应实验数据 Geant4 光子能量输入数据

Polyethylene glycol has immunoprotective effects on sciatic allografts, but behavioral recovery and graft tolerance require neurorrhaphy and axonal fusion

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Neural Regeneration Research 2025年第4期20卷 1192-1206页

作者： Tyler A.Smith liwen Zhou Cameron l.Ghergherehchi Michelle Mikesh Cathy Z.Yang Haley O.Tucker JuliAnne Allgood Jared S.Bushman George d.Bittner department of Molecular Biosciences University of Texas at AustinAustinTXUSA department of Neuroscience University of Texas at AustinAustinTXUSA division of Pharmaceutical Sciences University of WyomingLaramieWYUSA

Behavioral recovery using(viable)peripheral nerve allografts to repair ablation-type(segmental-loss)peripheral nerve injuries is delayed or poor due to slow and inaccurate axonal ***,such peripheral nerve allografts undergo immunological rejection by the host immune *** contrast,peripheral nerve injuries repaired by polyethylene glycol fusion of peripheral nerve allografts exhibit excellent behavioral recovery within weeks,reduced immune responses,and many axons do not undergo Wallerian *** relative contribution of neurorrhaphy and polyethylene glycol-fusion of axons versus the effects of polyethylene glycol per se was unknown prior to this *** hypothesized that polyethylene glycol might have some immune-protective effects,but polyethylene glycol-fusion was necessary to prevent Wallerian degeneration and functional/behavioral *** examined how polyethylene glycol solutions per se affect functional and behavioral recovery and peripheral nerve allograft morphological and immunological responses in the absence of polyethylene glycol-induced axonal ***-type sciatic nerve injuries in outbred Sprague–dawley rats were repaired according to a modified protocol using the same solutions as polyethylene glycol-fused peripheral nerve allografts,but peripheral nerve allografts were loose-sutured(loose-sutured polyethylene glycol)with an intentional gap of 1–2 mm to prevent fusion by polyethylene glycol of peripheral nerve allograft axons with host *** to negative control peripheral nerve allografts not treated by polyethylene glycol and in contrast to polyethylene glycol-fused peripheral nerve allografts,animals with loose-sutured polyethylene glycol peripheral nerve allografts exhibited Wallerian degeneration for all axons and myelin degeneration by 7 days postoperatively and did not recover sciatic-mediated behavioral functions by 42 days *** morphological signs of rejection,such as col

关键词： allograft rejection axotomy macrophage myelin nerve repair polyethylene glycol(PEG) sciatic nerve T cell transplantation Wallerian degeneration

Beginning from the end:the presynaptic terminal as a pathomechanism hub in frontotemporal dementia and amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第11期20卷 3217-3218页

作者： laura Huggon Emma l.Clayton UK dementia Research Institute at King’s College london LondonUK department of Basic and Clinical Neuroscience Institute of Psychiatry Psychology&NeuroscienceKing’s College LondonLondonUK

Frontotemporal dementia and amyotrophic lateral sclerosis:Frontotemporal dementia(F T d)and amyo t rophic lateral sclerosis(AlS)are neurodegenerative diseases with significant overlapping *** these neurodegenerative diseases affect different neuronal populations(with FTd affecting neurons of the frontal and temporal lobes,and AlS affecting upper and lower motor neurons),these two diseases are complexly *** and AlS exist on a disease spectrum,with shared genetic causes,clinical presentations,and pathologies.

关键词： diseases amyotrophic sclerosis

Remaking a connection:molecular players involved in post-injury synapse formation

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Neural Regeneration Research 2025年第6期20卷 1719-1720页

作者： diogo Tomé Ramiro d.Almeida iBiMEd-Institute of Biomedicine Department of Medical SciencesUniversity of AveiroAveiroPortugal CNC-Center for Neuroscience and Cell Biology University of CoimbraCoimbraPortugal

Functional recovery from central nervous system(CNS)trauma depends not only on axon regeneration or compensatory sprouting of uninjured fibers but also on the ability of newly grown axons to establish functional synapses with appropriate *** several studies have successfully promoted long-distance axonal regeneration in distinct CNS injury models,none of them have resulted in a viable therapeutic approach for patient recovery.A possible reason may be the lack of new synaptogenesis for reestablishing the circuitry lost after ***,we discuss how our understanding of the mechanisms that instruct synapse formation in the injured nervous system may contribute to the design of new strategies to promote functional restoration in traumatic CNS disorders.

关键词： viable injury instru

Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon C.Smith Jessica l.Williams department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(CNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage