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In-depth examination of hyperproliferative healing in two breeds of Sus scrofa domesticus commonly used for research

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Animal Models and Experimental Medicine 2021年第4期4卷 406-417页

作者： Colton H.Funkhouser Liam d.Kirkpatrick Robert d.Smith Lauren T.Moffatt Jeffrey W.Shupp Bonnie C.Carney Firefighters'Burn and Surgical Research Laboratory MedStar Health Research InstituteWashingtonDistrict of ColumbiaUSA department of Biochemistry and Molecular and Cellular Biology Georgetown University Medical CenterWashingtonDistrict of ColumbiaUSA department of Surgery Georgetown University School of MedicineWashingtonDistrict of ColumbiaUSA The Burn Center Department of SurgeryMedStar Washington Hospital CenterWashingtonDistrict of ColumbiaUSA

Background:Wound healing can result in various outcomes,including hypertrophic scar(HTS).Pigs serve as models to study wound healing as their skin shares physi-ologic similarity with ***(Yk)and duroc(dc)pigs have been used to mimic normal and abnormal wound healing,*** reason behind this differential healing phenotype was explored ***:Excisional wounds were made on dc and Yk pigs and were sampled and imaged for 98 *** arrays were used to determine differential gene *** Scar Scale(VSS)scores were ***-epithelialization was analyzed.H&E,Mason's trichrome,and immunostains were used to determine cellularity,col-lagen content,and blood vessel density,***:Yk wounds heal to a“port wine”HTS,resembling scarring in Fitzpatrick skin types(FST)*** wounds heal to a dyspigmented,non-pliable HTS,resembling scarring in FST *** expression during wound healing was differentially regulated versus uninjured skin in 40/80 genes,15 of which differed between *** scars had a higher VSS score at all time *** and dc wounds had equivalent re-epithelialization,collagen disorganization,and blood vessel ***:Our findings demonstrate that dc and Yk pigs can produce *** creation and healing were consistent among breeds,and differences in gene expression were not sufficient to explain differences in resulting scar *** pig breeds should be used in animal models to investigate novel therapeutics to provide insight into a treatment's effectiveness on various skin types.

关键词： animal models burns Fitzpatrick skin type hypertrophic scar wound healing

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THE PREParATION ANd CHarACTERISTICS STUdY OF TiN_xO_y SPECTRAL SELECTIVE ABSORBING FILM BY MAGNETRON SPUTTERING

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Acta Metallurgica Sinica(English Letters) 2005年第3期18卷 385-388页

作者： d.Chen H.Shen B.W.Wang H.Q.Wang MaterialandScienceEngineeringInstitute SouthChinaUniversityofTechnologyGuangzhou510641China EnergyEngineeringInstitute ZhongshanUniversityGuangzhou510275China／／GuangzhouInstituteofEnergyConversionTheChineseAcademyofSciencesGuangzhou510640China GuangzhouInstituteofEnergyConversion TheChineseAcademyofSciencesGuangzhou510640China SchoolofMechanismandAutomobile ShenyangInstituteofAeronauticalEngineeringShenyang110034China

Spectral selective absorbent film is a crucial factor for the solar heating devi ce. There are many kinds of spectral selective absorbing film made by different ways. TiNxOy thin film with excellent spectral selecting absobent property were successfully prepared by dC magnetron sputtering with ar as working gas, N2 and O2 as reactive gas, 99.9% titanium as the target and is copper slice as the subs trate. In this article, the optical characteristics and microstructure of TiNxO y thin film were studied. Inputing O2 can decrease the reflection of the visible lights, and double layer film can get good absorption for solar energy.

关键词： spectrum selecting absorbent film TiNxOy magnetron sputtering

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Helicobacter pylori infection in obesity and its clinical outcome after bariatric surgery

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World Journal of Gastroenterology 2014年第3期20卷 647-653页

作者： Marilia Carabotti Chiara d'Ercole Angelo Iossa Enrico Corazziari Gianfranco Silecchia Carola Severi department of Internal Medicine and Medical Specialties University Sapienza department of Medical Surgical Sciences and Biotechnology University Sapienza

The present review summarizes the prevalence and active clinical problems in obese patients with Helicobacter pylori(***)infection,as well as the outcomes after bariatric surgery in this patient *** involvement of *** in the pathophysiology of obesity is still *** may be that the infection is protective against obesity,because of the gastritis-induced decrease in production and secretion of the orexigenic hormone ***,recent epidemiological studies have failed to show an association between *** infection and reduced body mass *** infection might represent a limiting factor in the access to bariatric bypass surgery,even if highquality evidence indicating the advantages of preoperative *** screening and eradication is *** clinical management of infection is complicated by the lower eradication rates with standard therapeutic regimens reported in obese patients than in the normalweight *** clinical studies to ameliorate both *** eradication rates and control the clinical outcomes of *** infection after different bariatric procedures are warranted.

关键词： Helicobacter pylori Obesity Bariatric surgery Ghrelin Antibiotic resistance

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Etching Fused Quartz With CHF_3/ar

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光电工程 1997年第S1期24卷 64-69,81页

作者：周明宝崔铮 d.Prewett 中国科学院光电技术研究所微细加工光学技术国家重点实验室英国卢瑟福国家实验室微结构中心

报道了用氟利昂ＣＨＦ３和氩气Ａｒ作工作气体的反应离子刻蚀融石英的技术，研究了气体流速、腔压和射频等离子体功率对刻蚀速度的影响，并分析了刻蚀工艺对样品表面的污染，同时也考察了刻蚀工艺的均匀性和重复性。为了优化刻蚀工艺，... 详细信息

报道了用氟利昂ＣＨＦ３和氩气Ａｒ作工作气体的反应离子刻蚀融石英的技术，研究了气体流速、腔压和射频等离子体功率对刻蚀速度的影响，并分析了刻蚀工艺对样品表面的污染，同时也考察了刻蚀工艺的均匀性和重复性。为了优化刻蚀工艺，采用Ｒｓ１／Ｄｉｓｃｏｖｅｒ软件工具设计优化实验。实验中射频等离子体功率在１２０～１６０Ｗ范围，氩气和氟利昂流速分别在１５～３５ｓｃｍ和２０～５０ｓｃｃｍ范围，腔压在１００～１４０ｍＴｏｒ范围，相应的刻蚀速度为１５～２５ｎｍ／ｍｉｎ。

关键词：石英离子腐蚀多层位相结构混合气体.

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SURFACE SEGREGATION EFFECTS IN AL_2O_3 IMPLANTEd WITH HIGH dOSE INdIUM

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Nuclear Science and Techniques 1990年第Z1期1卷 99-104页

作者：曹德新 d.K.Sood Shanghai Institute of Nuclear Rcsearch Academia SinicaShanghai 201800 China Microelectronics & Materials Technology Centre Royal Melbourne Institute of Technology 124 Latrobe Street Melbourne Victoria 3001. Australia

Implantations of 100 keV In ions to high dose of 6 ×1016 In/cm2 were performed into a-axis oriented crystals of Al2O3 held at a liquid nitrogen temperature. The implantation produced about 80nm thick amorphous surface layer. Isothermal annealing in flowing ar gas ambient was done at the temperatures of 600, 700, 800, and 900℃ . Rutherford backscattering and channeling (RBS-C), scanning electron microscope (SEM) and reflection high energy electron diffraction (RHEEd) have been employed to investigate the annealing *** indium shows anomalous diffusion in amorphous layer. The migration of indium was composed of two parts: (a) some broadening of In profile corresponding to diffusion within the amorphous layer, (b) segregation of In to surface to form In2O3 which appears as islands on the surface. When the ambient is made oxygen free, the segregated In is lost by evaporation at the surface.

关键词： Surface segregation effects Ion implanted Isothermal annealing

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Angular dependence of nanoparticle generation in the matrix assembly cluster source

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Nano Research 2019年第12期12卷 3069-3074页

作者： Maria Chiara Spadaro Junlei Zhao William d.Terry Jian Liu Feng Yin Flyura djurabekova Richard E.Palmer College of Engineering Swansea UniversityBay CampusFabian WaySwansea SAI 8ENUK department of Physics and Helsinki Institute of Physics University of HelsinkiP.O.Box43f FIN-00014HelsinkiFinland Nanoscale Physics Research Laboratory School of Physics and AstronomyUniversity of BirminghamBirmingham B152TTUK National Center for Electron Microscopy in Beijing Key Laboratory cf Advanced Materials(MOE)The State Key Laboratory of New Ceramics and Fine ProcessingSchool of Materials Science and EngineeringTsinghua UniversityBeijing 100084China School of Physics and Information Technology Shaanxi Normal UniversityXian 710062China Catalan Institute of Nanoscience and Nanotechnology(ICN2) CSIC and BISTCampus UABBellaterra08193 BarcelonaCataloniaSpain

The matrix assembly cluster source(MACS)represents a bridge between conventional instruments for cluster beam deposition(CBd)and thelevel of industrial *** method is based on ar^+ion sputtering of a pre-condensed ar-M matrix(where M,is typically a metal such asAg).Each ar^+ion produces a collision cascade and thus the formation of metal clusters is in the matrix,which are then sputtered *** wepresent an experimental and computational investigation of the cluster emission process,specifically its dependence on the ar^+ion angle of in cidence and the cluster emission *** find the in cide nee angle strongly in flue nces the emerging cluster flux,which is assigned to thespatial location of the deposited primary ion energy relative to the cluster into the *** also found an approximately constant anglebetween the incident ion beam and the peak in the emitted cluster distribution,with value between 99°and 109°.

关键词： cluster beam deposition scale-up nano particles silver ligand-free green synthesis

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The modifying influence of HLA classⅡdQB1^(*)06:02 on the Streptococcus and clinical phenotype correlation among anti-Ro+mothers of children with neonatal lupus

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Genes & diseases 2023年第4期10卷 1169-1171页

作者： Robert M.Clancy Carla J.Guthridge Miranda C.Marion Joel Guthridge Timothy d.Howard Peter M.Izmirly Mala Masson Jill P.Buyon Judith A.James Carl d.Langefeld department of Medicine Division of RheumatologyNYU Grossman School of MedicineNew YorkNY 10016USA arthritis and Clinical Immunology Oklahoma Medical Research FoundationOklahoma CityOK 73104USA department of Biostatistics and data Science Wake Forest School of MedicineWinstone SalemNC 27101USA Center for Precision Medicine Wake Forest School of MedicineWinstoneSalemNC 27101USA department of Biochemistry Wake Forest School of MedicineWinstoneSalemNC 27101USA

The genus Streptococcus,a gram-positive bacterium,con-tains species associated with immune activation at morbid outcomes,including scarlet fever,endocarditis,meningitis,and rheumatic *** both stool and saliva,there is a pos-itive correlation between Streptococcus abundance and Sjogren’s syndrome(SS)and systemic lupus erythematosus(SLE).

关键词： lupus mother fever Streptococcus

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development and application of functional gene arrays for microbial community analysis

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中国有色金属学会会刊：英文版 2008年第6期18卷 1319-1327页

作者： Z. L. HE J. d. VAN NOSTRANd L.Y. WU J. Z. ZHOU Institute for Environmental Genomics Department of Botany and Microbiology University of Oklahoma Norman OK 73019 USA

功能的基因标记能关于功能的基因差异和微生物引起的社区的潜在的活动提供重要信息。尽管 microarray 技术成功地被使用了为纯文化学习基因表示，简单、人工的微生物引起的社区，改编如此的一种技术分析复杂微生物引起的社区仍然以设计... 详细信息

功能的基因标记能关于功能的基因差异和微生物引起的社区的潜在的活动提供重要信息。尽管 microarray 技术成功地被使用了为纯文化学习基因表示，简单、人工的微生物引起的社区，改编如此的一种技术分析复杂微生物引起的社区仍然以设计，样品准备，和数据分析提出很多挑战。这个工作集中于功能的基因数组(FGA ) 的开发和应用程序为微生物引起的社区研究指向关键功能的基因标记。一些与 FGA 有关明确地给问题调音，例如 oligonucleotide 探查设计， nucleic 酸抽取和纯化，数据分析，特性，敏感，和量的能力详细被讨论。最近的研究证明了 FGA 能从许多自然环境关于微生物引起的社区提供特定、敏感、潜在地量的信息并且控制生态系统。这种技术被期望革命化微生物引起的社区的分析，并且连接微生物引起的结构到生态系统工作。

关键词：微数列应用函数基因标记微生物种群

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Particulier酒店(5区) 慈善实验室

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城市环境设计 2017年第1期 338-341页

作者： Agence Perrot Richard Atelier Paul arène Pierre-Alexandre Risser Horticulture Jardins

场地信息:预期功能:没有具体的预期地址:B?cherie街15号(5区)所有权人:巴黎市政府地块面积:500m2使用面积:1 847m2(净建筑面积)限高:25m获奖团队 :项目运营:Compagnie de Phalsbourg项目支持:ITF Bruno Georges、Bet développement durable、Cuisine Mode d'emploi(s)历史与现状这座宏伟的15世纪私人府邸是受官方保护的历史文物,最初由巴黎医学院使用。16世纪扩建完成,增添

关键词：慈善巴黎法国 Particulier 地面层赞助商医学院医学院校实验室地下室地下建筑物建筑

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Some stromatic pyrenomycetous fungi from northern ***,Camillea and Hypoxylon(Xylariaceae)

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Fungal diversity 2012年第4期55卷 65-76页

作者： L.N.Vasilyeva S.L.Stephenson K.d.Hyde A.H.Bahkali Institute of Biology and Soil Science Far East Branch of the Russian Academy of SciencesVladivostok 690022Russia University of arkansas FayettevilleAR 72701USA Institute of Excellence in Fungal Research Mae Fah Lung UniversityChiang Rai 57100Thailand School of Science Mae Fah Lung UniversityChiang Rai 57100Thailand Botany and Microbiology department College of ScienceKing Saud UniversityRiyadh 11442Saudi Arabia

Fourteen species of stromatic pyrenomycetous fungi(family Xylariaceae)collected in northern Thailand are *** of these(Biscogniauxia lithocarpi,Camillea malaysiensis ***,Hypoxylon juventuterubrum,***,***,and ***)are described as taxa new to *** of these taxa are provided,and they are compared with similar taxa known from the Western Hemisphere.

关键词： Ascomycota SE Asia Taxonomy Xylariales

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