检索结果-南通市图书馆

World Journal of Traditional Chinese Medicine 2015年第4期1卷 93-94页

作者： Shu J Kuchta K He Y deng Y Lin Y Ye G Lv X Liu X kobayashi Y department of Gastroenterology Guangzhou Red Cross Hospital Jinan University National Institute of Health Sciences Division of Pharmacognosy Medical Corporation Soujikai Faculty of Medicine Shimane University

HSCs were divided into four groups,namely control group(A),Myd88 siRNA group(B),curcumin group(C),and curcumin+Myd88 siRNA group(d).Groups B and d were subjected to transient transfection with siRNA for *** C and d were incubated with curcumin(25μmol/L)for ***88 protein expression was observed by Western Blot,apoptosis was detected by flow cytometry,

关键词： siRNA

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儿童高度近视眼的眼底特点

世界核心医学期刊文摘(眼科学分册) 2006年第1期 58-59页

作者： kobayashi K. Ohno-Matsui K. Kojima A. 邢咏新 department of Ophthalmology and Visual Science Tokyo Medical and Dental University 1-5-45 Yushima Bunkyo-ku Tokyo 113-8519 Japan

Purpose: To evaluate the fundus characteristics of highly myopic eyes in children. Methods: We reviewed the medical records of 46 children (1 to 8 years old; mean age, 6.8 years) (80 eyes) with high myopia (4 d or more for children younger than 5 years, 6 d or more for children aged 6-8 years) seen consecutively during a 10-year period at the high-myopia clinic in our hospital. Children of up to 8 years of age at the initial visit were included in the study. Results: Fundus examination revealed posterior staphyloma in only one eye (1.3% ) and mild chorioretinal atrophy around the optic disc in 13 eyes (16.3% ). There were no patients with choroidal neovascularization or geographic atrophy in the posterior fundus. Myopic peripapillary crescent was observed in 26 eyes (33.8% ), but the area of the crescent was relatively small (mean, 0.5 disc area). Conclusions: The results of the present study showed that myopic fundus changes are uncommon and mild in children. They suggest that aging, in addition to mechanical stretching of the eyeball, might be important for the development of myopic fundus changes.

关键词：高度近视眼儿童眼底改变

Integrated genome-wide differentiation and association analyses identify causal genes underlying breeding-selected grain quality traits in japonica rice

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Molecular Plant 2023年第9期16卷 1460-1477页

作者： Hideki Yoshida Satoshi Okada Fanmiao Wang Shohei Shiota Masaki Mori Mayuko Kawamura Xue Zhao Yiqiao Wang Naho Nishigaki Asako kobayashi Kotaro Miura Shinya Yoshida Masaru Ikegami Akitoshi Ito Lin-Tzu Huang Yue-le Caroline Hsing Yoshiyuki Yamagata Yoichi Morinaka Masanori Yamasaki Toshihisa Kotake Eiji Yamamoto Jian Sun Ko Hirano Makoto Matsuoka Institute of Fermentation Sciences Fukushima UniversityFukushima 960-1248Japan Bioscience and Biotechnology Center Nagoya UniversityNagoyaAichi 464-8601Japan Food Resources Education and Research Center Graduate School of Agricultural ScienceKobe UniversityUzuranoKasaiHyogo 675-2103Japan Research Center of Genetic Resources NARO2-1-1 KannondaiTsukubaIbaraki 305-8602Japan Rice Research Institute Shenyang Agricultural UniversityShenyangChina division of Life Science Graduate School of Science and EngineeringSaitama University255 Shimo-okuboSakura-kuSaitamaJapan Fukui Agricultural Experiment Station Fukui 918-8215Japan department of Bioscience and Biotechnology Fukui Prefectural UniversityFukui 910-1195Japan Hyogo Prefectural Research Center for Agriculture Forestry and FisheriesKasaiHyogo 679-0198Japan Research Insttute for Food and Agriculture Ryukoku UniversityOotsuShiga 520-2194Japan Food Research Centre Aichi Centre for Industry and Science Technology2-1-1 Shimpukuji-choNagoyaAichi 451-0083Japan institute of Plant and Microbial Biology Academia SinicaTaipeiTaiwanChina department of Agronomy National Taiwan UniversityTaipeiTaiwanChina lant Breeding Laboratory Facultyf gricultureKyushu University744MoookaNishikuFukukaJapan Graduate School of Agiculture Meji University1-1-1 Higashi-MitaTama-kuKawasakiKanagawa 214571Japa Crop Science Laboratory Faculty of AgricultureNigata UniversityIkarashiNishi-kuNigata 950-2181Japan

Improving grain quality is a primary objective in contemporary rice *** modern rice breeding has developed two different types of rice,eating and sake-brewing rice,with different grain characteristics,indicating the selection of variant gene alleles during the breeding *** the critical importance of promptly and efficiently identifying genes selected in past breeding for future molecular breeding,we conducted genome scans for divergence,genome-wide association studies,and map-based ***,we successfully identified two genes,OsMnS and OsWOX9d,both contributing to rice grain *** encodes a mannan synthase that increases the white core frequency in the endosperm,a desirable trait for sake brewing but decreases the grain appearance ***9d encodes a grass-specific homeobox-containing transcription factor,which enhances grain width for better sake ***,haplotype analysis revealed that their defective alleles were selected in East Asia,but not Europe,during modern *** addition,our analyses indicate that a reduction in grain mannan content during African rice domestication may also be caused a defective OsMnS allele due to breeding *** study not only reveals the delicate balance between grain appearance quality and nutrition in rice but also provides a new strategy for isolating causal genes underlying complex traits,based on the concept of“breeding-assisted genomics”in plants.

关键词： rice grain quality sake brewing mannan genomic analysis

CONCEPTUAL dESIGN STUdY ON SULFURIC-ACId dECOMPOSER FOR THERMO-CHEMICAL IOdINE-SULFUR PROCESS

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CONCEPTUAL DESIGN STUDY ON SULFURIC-ACID DECOMPOSER FOR THER...

第十三届国际核工程大会

作者： Hiroyuki Ota Seiji Kasahara Atsuhiko Terada Masatoshi Hodotsuka Shinji Kubo Ryutaro Hino Takanari Inatomi Kenji Ogura Masahiko kobayashi Shigeki Maruyama department of Advanced Nuclear Heat Technology Japan Atomic Energy Research Institute Japan Atomic Energy Research Institute Toshiba Corporation Toshiba Corporation IPS CompanyAdvanced Systems Design & Engineering Dept

The Japan Atomic Energy Research Institute(JAERI) has been conducting R&d on HTGR and also on thermo-chemical hydrogen production by using a thermo-chemical iodine-sulfur cycle(IS process).In the I

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基因检测对儿童癫痫性脑病的检出率

癫痫杂志 2016年第6期2卷 527-534页

作者： Mercimek-Mahmutoglu S Patel J Cordeiro d Hewson S Callen d donner EJ Hahn Cd Kannu P kobayashi J Minassian BA Moharir M Siriwardena K Weiss SK Weksberg R Snead OC 童馨(译) 慕洁(审) 不详

癫痫是儿童期常见的神经系统疾病,为了明确癫痫性脑病的基因检出率,对一个癫痫遗传诊所进行了一项回顾性队列研究.2012年1月-2014年6月,在一个癫痫遗传诊所纳入了所有兼有难治性癫痫、整体性发育迟滞和认知功能障碍的患者.通过回顾电子... 详细信息

癫痫是儿童期常见的神经系统疾病,为了明确癫痫性脑病的基因检出率,对一个癫痫遗传诊所进行了一项回顾性队列研究.2012年1月-2014年6月,在一个癫痫遗传诊所纳入了所有兼有难治性癫痫、整体性发育迟滞和认知功能障碍的患者.通过回顾电子病历,获得了患者的临床特征、神经影像、生化检验及分子遗传学资料,包括对癫痫性脑病基因的第二代目的基因测序.在110例患者中,发现28%是有基因异常的:7%有遗传性代谢障碍,包括由ALdH7A1变异引起的吡哆醇依赖性癫痫、Menkes病、吡哆醇-5-磷酸氧化酶缺乏、钴胺素G缺乏、亚甲基四氢叶酸还原酶缺乏、Ⅰ型葡萄糖载体缺陷、甘氨酸脑病和丙酮酸脱氢酶复合体缺陷;21%有其他的基因病因,包括遗传性综合征、在阵列比较基因组杂交上的致病性拷贝数变异,以及与SCN1A、SCN2A、SCN8A、KCNQ2、STXBP1、PCdH19和SLC9A6基因变异相关的癫痫性脑病.4.5%的患者得到了由第二代目的基因测序的癫痫性脑病面板作出的基因诊断.值得注意的是,4.5%的患者有可治的遗传性代谢性疾病.该研究为首个将遗传性代谢障碍和癫痫性脑病的其他遗传病因结合起来的研究.第二代目的基因测序面板将癫痫性脑病患者的基因诊断检出率从25%.

关键词：癫痫基因代谢障碍染色体分子遗传学

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红色毛癣菌引起的深在囊状癣

世界核心医学期刊文摘（皮肤病学分册） 2006年第4期2卷 10-11页

作者： kobayashi M. Ishida E. YasudaH. 李政霄 department of dermatology University of Occupational and Environmental Health 1- 1 Iseigaoka Yahatanishi-ku Kitakyushu 807- 8555 JapanDr.

A 57-year-old Japanese woman developed multiple subcutaneous cysts located on the pubic region, thighs, back, and buttocks. She had been treated with systemic prednisolone and azathioprine for 3 years because of autoimmune hepatitis. Histologic examination revealed that the lesions were pseudocysts with numerous spores and hyphae. Trichophyton rubrum was identified in culture from the content of several examined cysts. The serum beta-d-glucan level was high (313 pg/mL), and a computed tomographic scan of the chest cavity showed infective embolism in the lung. To our best knowledge, this is the first reported case of multiple-cystic tinea profunda,presumably with systemic dermatophyte infection. Systemic T-cell immunosuppression, as represented by a relatively low percentage of memory T cells and negative delayed-type hypersensitivity tests, is considered to cause this rare manifestation of dermatophytosis.

关键词：红色毛癣菌皮肤癣菌感染皮肤癣菌病感染性栓塞自身免疫性肝炎皮下囊肿组织学检查迟发型超敏反

Fabrication of MEMS diaphragm Transducer Array Based on Epitaxial PZT Thin Film for 2-d Hydrophone Application

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Fabrication of MEMS Diaphragm Transducer Array Based on Epit...

Influence of percutaneous local therapy for hepatocellular carcinoma on gastric function

2008 IEEE International Ultrasonics Symposium

作者： Nagaya Okada Kazuki Higuchi Yoshiyuki Asakura Kazuto kobayashi Mikinori Ito Masashi Takabe Mikito Otonari Ikuo Kanja daisukc Akai Kazuaki Sawada Makoto Ishida HONdA ELECTRONICS CO. LID. Toyohashi University of Technology

＜正＞Background,Motivation and Objective The increasing interest in 3-d imaging and high frequency applications leads to investigate new solutions for transducer *** an adequate signal-to-noise ratio with piezoelectr...

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World Journal of Gastroenterology 2013年第10期19卷 1618-1624页

作者： Mitsuyoshi kobayashi Fumihiko Kinekawa Kazuya Matsuda Shintaro Fujihara Noriko Nishiyama Takako Nomura Joji Tani Hisaaki Miyoshi Hideki Kobara Akihiro deguchi Hirohito Yoneyama Hirohito Mori Tsutomu Masaki department of Gastroenterology and Neurology Faculty of MedicineKagawa UniversityMiki-choKita-gunKagawa 761-0793Japan department of Internal Medicine Sanuki Municipal HospitalSanuki-cityKagawa 769-2393Japan department of Internal Medicine Matsuda ClinicTakamatsu-cityKagawa 760-0071Japan

AIM:To investigate the influence of percutaneous local therapy on gastric myoelectrical activity in patients with hepatocellular ***:Forty-four patients with hepatocellular carcinoma(HCC) [27 males and 17 females,ranging in age from 49 to 81 years old(69.7 ± 8.01 years)] who were admitted for percutaneous local therapy were enrolled in this *** examined clinical abdominal symptoms using the Gastrointestinal Symptom Rating Scale(GSRS) before and 3 d after percutaneous local *** also measured cutaneous fasting and postprandial electrogastrography(EGG) recordings before and 3 d after percutaneous local ***:We found that the percentage of normogastria in the fasting period was lower in the Child B group than in the Child A group(66.8% ± 8.6% vs 84.0% ± 3.8%).After percutaneous local therapy for HCC,the percentages of normogastria in the fasting period were significantly decreased(81.6% ± 3.5% vs 75.2% ± 4.5%).None of the postprandial EGG parameters changed significantly after percutaneous local therapy for *** local therapy for HCC reduced the power ratio(PR).In particular,the PR of tachygastria was significantly decreased after therapy(P differences were found in the postprandial EGG ***,no significant differences were found in the calculated GSRS scores obtained from the questionnaire before and after ***:Gastric slow-wave dysrhythmias were induced by percutaneous local therapy in HCC patients,even though the GSRS scores obtained from the questionnaire did not change significantly.

关键词： Gastric myoelectrical activity Electrogastrography Hepatocellular carcinoma Percutaneous ethanol injection Radiofrequency ablation

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含碳掺氨燃料的研究进展

化工进展 2023年第9期42卷 4603-4615页

作者：赖诗妮江丽霞李军黄宏宇小林敬幸中国科学院广州能源研究所广东广州510640 中国科学技术大学能源科学与技术学院广东广州510640 中国科学院重大科技任务局北京100864 江西省碳中和研究中心江西南昌330096 南方海洋科学与工程广东省实验室(广州) 广东广州511458 名古屋大学化学系统工程系日本名古屋464-8603

随着经济和社会的发展,国家对能源的需求量越来越大,这与化石能源短缺、环境污染、温室效应等问题相矛盾,因此寻找高效清洁的替代燃料势在必行。氨的体积能量密度较高、成本低且完全燃烧时产物的污染性小,具有成为新时代绿色能源的潜力... 详细信息

随着经济和社会的发展,国家对能源的需求量越来越大,这与化石能源短缺、环境污染、温室效应等问题相矛盾,因此寻找高效清洁的替代燃料势在必行。氨的体积能量密度较高、成本低且完全燃烧时产物的污染性小,具有成为新时代绿色能源的潜力。但它的燃烧性能较差,通常需要掺混煤、CH_(4)和合成气等燃料来改善。本文主要介绍了含碳掺氨的煤掺氨和甲烷掺氨混合燃料在基础燃烧特性和燃烧应用优化方面的研究进展。总结了不同燃烧策略及燃烧器设计中掺混氨燃料的燃烧特性和排放规律,为未来工业化应用研究提供一定的参考。但在实际应用氨燃料过程中仍存在不少挑战,未来可进一步对优化分级燃烧的策略、改善相关燃烧设备的结构、调整含氨燃料的喷射方式等方面进行研究,以实现高效低污染氨燃料的应用目标。

关键词：燃料氨甲烷煤燃烧氮氧化物

不同阴极催化剂对城市垃圾渗滤液微生物燃料电池处理的影响

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太阳能学报 2015年第7期36卷 1779-1785页

作者：袁浩然邓丽芳黄宏宇陈勇小林敬幸中国科学院广州能源研究所广州510640 中国科学院可再生能源重点实验室广州510640 中国科学院广州分院广州510070

以城市垃圾渗滤液为阳极液基质,比较以MnO_2和TiO_2为阴极催化剂时,对MFC电池性能以及渗滤液中有机污染物去除率的影响。结果表明,MnO_2和TiO_2作为阴极催化剂,可催化氧化阴极最终电子受体(O_2)、提高电子传递速率,最终提高电池性能。... 详细信息

以城市垃圾渗滤液为阳极液基质,比较以MnO_2和TiO_2为阴极催化剂时,对MFC电池性能以及渗滤液中有机污染物去除率的影响。结果表明,MnO_2和TiO_2作为阴极催化剂,可催化氧化阴极最终电子受体(O_2)、提高电子传递速率,最终提高电池性能。阴极负载MnO_2后,电池性能显著提高,稳定输出电压和最大功率密度分别增大到0.43 V和0.89 W/m^3。与未负载阴极催化剂的MFC相比,经MFC运行7 d后,渗滤液中的生物需氧量(BOd)和NH_4^+-N去除率分别提高8.1%和5.0%,达72.9%和91.6%。但由于缺少光照,阴极负载TiO_2后电池性能无明显改善,稳定输出电压仅为0.23 V,最大功率密度仅0.12 W/m^3,且渗滤液中有机污染物的BOd和NH_4^+-N去除率比负载MnO_2催化剂的MFC低8.8%和5.7%。

关键词：微生物燃料电池渗滤液 MnO2 TiO2 催化反应机制