检索结果-南通市图书馆

Mn-containing bioceramics inhibit osteoclastogenesis and promote osteoporotic bone regeneration via scavenging ROS

Bioactive Materials 2021年第11期6卷 3839-3850页

作者： Jianmei Li cuijun deng Wanyuan Liang Fei Kang Yun Bai Bing Ma Chengtie Wu Shiwu Dong Department of Biomedical Materials Science School of Biomedical EngineeringThird Military Medical University(Army Medical University)Chongqing400038China State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai200050China State Key Laboratory of Trauma Burnsand Combined InjuryThird Military Medical University(Army Medical University)Chongqing400038China

Osteoporosis is caused by an osteoclast activation *** suffering from osteoporosis are prone to bone *** evidence indicates that scavenging reactive oxygen species(ROS)can inhibit receptor activator of nuclear factorκB ligand(RANKL)-induced osteoclastogenesis and suppress ovariectomy-induced *** is critical to develop biomaterials with antioxidant properties to modulate osteoclast activity for treating osteoporotic bone *** studies have shown that manganese(Mn)can improve bone regeneration,and Mn supplementation may treat ***,the effect of Mn on osteoclasts and the role of Mn in osteoporotic bone defects remain *** present research,a model bioceramic,Mn-containedβ-tricalcium phosphate(Mn-TCP)was prepared by introducing Mn intoβ-*** introduction of Mn intoβ-TCP significantly improved the scavenging of oxygen radicals and nitrogen radicals,demonstrating that Mn-TCP bioceramics might have antioxidant *** in vitro and in vivo findings revealed that Mn^(2+)ions released from Mn-TCP bioceramics could distinctly inhibit the formation and function of osteoclasts,promote the differentiation of osteoblasts,and accelerate bone regeneration under osteoporotic conditions in ***,Mn-TCP bioceramics inhibited osteoclastogenesis and promoted the regeneration of osteoporotic bone defects by scavenging ROS via Nrf2 *** results suggest that Mn-containing bioceramics with osteoconductivity,ROS scavenging and bone resorption inhibition abilities may be an ideal biomaterial for the treatment of osteoporotic bone defect.

关键词： Mn-containing bioceramics Antioxidant biomaterials Osteoclastogenesis ROS Osteoporotic bone regeneration

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Diatomite-incorporated hierarchical scaffolds for osteochondral regeneration

引用

Bioactive Materials 2024年第8期38卷 305-320页

作者： cuijun deng Chen Qin Zhenguang Li Laiya Lu Yifan Tong Jiaqi Yuan Feng Yin Yu Cheng Chengtie Wu Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation Clinical Research Center for Anesthesiology and Perioperative MedicineTranslational Research Institute of Brain and Brain-Like IntelligenceShanghai Fourth People’s HospitalSchool of MedicineTongji UniversityShanghai200434PR China State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai200050PR China Department of Joint Surgery Shanghai East HospitalSchool of MedicineTongji University150 Jimo RoadShanghai200032PR China State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceFudan UniversityShanghai200438PR China

Osteochondral regeneration involves the highly challenging and complex reconstruction of cartilage and subchondral ***(Si)ions play a crucial role in bone *** research on Si ions mainly focuses on bone repair,by using silicate bioceramics with complex ion ***,it is unclear whether the Si ions have important effect on cartilage *** a scaffold that solely releases Si ions to simultaneously promote subchondral bone repair and stimulate cartilage regeneration is critically ***(DE)is a natural diatomaceous sediment that can stably release Si ions,known for its abundant availability,low cost,and environmental ***,a hierarchical osteochondral repair scaffold is uniquely designed by incorporating gradient DE into GelMA *** adding DE microparticles provides a specific Si source for controlled Si ions release,which not only promotes osteogenic differentiation of rBMSCs(rabbit bone marrow mesenchymal stem cells)but also enhances proliferation and maturation of ***,DE-incorporated hierarchical scaffolds significantly promoted the regeneration of cartilage and subchondral *** study suggests the significant role of Si ions in promoting cartilage regeneration and solidifies their foundational role in enhancing bone ***,it offers an economic and eco-friendly strategy for developing high value-added osteochondral regenerative bioscaffolds from low-value ocean natural materials.

关键词： Diatomite Si release Hierarchical scaffolds 3D printing Osteochondral regeneration

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Taxonomic review of Chinese ant genus Probolomyrmex(Hymenoptera:Formicidae)

引用

Zoological Systematics 2022年第2期47卷 146-154页

作者： cuijun Liang Zhilin Chen Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection(Guangxi Normal University) Ministry of EducationGuilin 541006China Guangxi Key Laboratory of Rare and Endangered Animal Ecology Guangxi Normal UniversityGuilin 541006China

Four species of the ant genus Probolomyrmex in the subfamily Proceratiinae are recognized in China,namely ***,***,*** and *** species,*** and *** are recorded in China for the first time.A key to the known Chinse spec... 详细信息

关键词： Taxonomy Proceratiinae new records

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Large-scale identification of expression quantitative trait loci in Arabidopsis reveals novel candidate regulators of immune responses and other processes

引用

Journal of Integrative Plant Biology 2020年第10期62卷 1469-1483页

作者： Xingang Wang Min Ren Danni Liu Dabao Zhang cuijun Zhang Zhaobo Lang Alberto PMacho Min Zhang Jian-Kang Zhu Department of Horticulture and Landscape Architecture Purdue UniversityWest LafayetteIndiana47907USA Cold Spring Harbor Laboratory Cold Spring HarborNew York11724USA Department of Statistics Purdue UniversityWest LafayetteIndiana47907USA Shanghai Center for Plant Stress Biology Center of Excellence for Molecular Plant SciencesShanghai 200032China

The extensive phenotypic diversity within natural populations of Arabidopsis is associated with differences in gene *** levels can be considered as in-heritable quantitative traits,and used to map expression quantitative trait loci(eQTL)in genome-wide association studies(GWASs).In order to identify putative genetic de-terminants for variations in gene expression,we used pub-licly available genomic and transcript variation data from 665 Arabidopsis accessions and applied the single nucleotide polymorphism-set(Sequence)Kernel Association Test(SKAT)method for the identification of ***,we used the penalized orthogonal-components regression(POCRE)method to increase the power of statistical ***,gene annotations were used as test units to identify genes that are associated with natural variations in transcript accumulation,which correspond to candidate regulators,some of which may have a broad impact on gene *** increasing the chances to identify real as-sociations,the analysis using POCRE and SKAT significantly reduced the computational cost required to analyze large *** a proof of concept,we used this approach to identify eQTL that represent novel candidate regulators of immune *** versatility of this approach allows its application to any process that is subjected to natural var-iation among Arabidopsis accessions.

关键词： expression. regulators traits

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

从社会经济角度分析新中国初期的政治体制建设

引用

中国特色社会主义研究 2005年第3期 56-61页

作者：马翠军南京大学

从社会经济结构角度来讲,新中国成立初期新政权面临的是低度整合的前现代化社会结构,这一结构构成近代以来中国政治发展的结构性制约因素。新中国政权建立初期主动把握这一社会结构所蕴含的政治趋向,实现了近代以来所有政治力量都无力... 详细信息

从社会经济结构角度来讲,新中国成立初期新政权面临的是低度整合的前现代化社会结构,这一结构构成近代以来中国政治发展的结构性制约因素。新中国政权建立初期主动把握这一社会结构所蕴含的政治趋向,实现了近代以来所有政治力量都无力可及的目标:新的国家与社会关系得以确立,新的政治运行机制诞生,基本达到了国家政权建设的目的。但是这一时段所表现出来的一系列政治现象诸如机构的精简—膨胀循环,强化行政管理体制与实施政治动员的交叠、体制条块间的权力消长、“一管就死、一放就乱”的反复等等,都成为今后中国更长时期的社会政治特征。从社会经济角度着手分析其原因,可以对20世纪中国政治发展的特征有一个整体把握。

关键词：社会经济角度党政二元主体政治体制政治动员计划经济体制

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Research of Data Mining Based on Neural Networks

The Research of Data Mining Based on Neural Networks

引用

2011 International Conference on Computer Science and Information Technology(ICCSIT 2011)

作者： Guoquan Jiang cuijun Zhao School of Computer Science and Technology Henan Polytechnic University School of Resources and Environment Engineering Henan Polytechnic University

ISBN: (纸本)9781510811249;1510811249

The traditional data mining algorithms are hard to apply on noisy data, redundant information, incomplete data and sparse data in database, or the application effects are not good. But neural network have many virtues such as robustness, parallelism and anti-noise, so it is very effective on data mining in large and real databases. This paper expounds the process of data mining based neural network in detail, discusses the algorithms of classifying and clustering, indicates the problems at present and makes an expectation for the development.

关键词： Data Mining (Dm) Neural Network (Nn) Self-Organizing Map

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

INVARIANT MEASURES AND UNIFORM POSITIVE ENTROPY PROPERTY FOR INVERSE LIMITS

引用

Applied Mathematics(A Journal of Chinese Universities) 1999年第3期14卷 265-272页

作者： He Lianfa Liu cuijun Dept. of Math., HebeiNorm alUniv., Shijiazhuang 050016. Dept. of Math. Hebei Normal Univ. Shijiazhuang

In this paper, the interconnection of som e ergodic properties betw een a continuous selfm ap and its inverse lim itis studied. Ithas been proved that(1) theirinvariantBorelproba- bility m easures are identicalup to hom eom orphism and (2) they preserve uniform positive en- tropy property sim ultaneously. As applications, it is also proved that the upper sem i-continu- ous properties of their entropy m aps are restricted each other, and the entropy m ap of the asym ptotically h-expansivecontinuous m ap isuppersem i-continuous, atthe sam e tim e acontin- uous m ap having u.p.e. is topologicalweak-m ixing.

关键词： Continuous m ap inverse lim it invariant m easure entropy map uniform positive entropy.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于众包的多楼层定位方法

引用

计算机研究与发展 2022年第2期59卷 452-462页

作者：罗娟章翠君王纯湖南大学信息科学与工程学院长沙410082

无线基础设施的广泛部署使得基于WiFi的指纹定位方法成为了最具普适性的定位方法之一.然而,指纹库构建过程的耗时费力阻碍了基于接收信号强度(received signal strength indication,RSSI)指纹定位的发展.针对指纹库构建难问题,提出了一... 详细信息

无线基础设施的广泛部署使得基于WiFi的指纹定位方法成为了最具普适性的定位方法之一.然而,指纹库构建过程的耗时费力阻碍了基于接收信号强度(received signal strength indication,RSSI)指纹定位的发展.针对指纹库构建难问题,提出了一种基于众包的低成本、高效率的多楼层指纹库构建方法-MCSLoc.首先将室内平面地图转换为室内语义地图;然后采集众包用户智能手机内置惯性传感单元(inertial measurement unit,IMU)数据,采用卡尔曼滤波(Kalman filter,KF)融合算法划分传感数据到所属楼层.提出分段式轨迹获取方法,根据传感数据获取用户相对轨迹和RSSI值序列;最后利用隐马尔可夫模型(hidden Markov model,HMM)和轨迹匹配维特比(track matching Viterbi,TM-Viterbi)算法将相对轨迹与室内语义地图主路径相匹配,为RSSI值序列标注楼层标签和物理位置标签.MCSLoc方法的HMM地图匹配算法无需用户初始位置,实现众包用户弱意识参与.实验结果表明MCSLoc可以快速获取轨迹绝对初始位置,有效构建多楼层指纹库,提高多楼层定位效率.

关键词：众包隐马尔可夫模型 WiFi指纹定位维特比算法地图匹配

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于移动激光扫描数据的铁路轨顶高程自动提取方法

引用

铁道学报 2021年第7期43卷 108-113页

作者：毛庆洲董翠军胡伟武汉大学测绘遥感信息工程国家重点实验室湖北武汉430079 武汉大学遥感信息工程学院湖北武汉430079 武汉大学时空数据智能获取技术与应用教育部工程研究中心湖北武汉430079

铁路轨顶面高程的精确获取对铁路的维护、改扩建工作至关重要。传统的测量方式存在安全性差、效率低、对运营干扰大等缺点。通过移动激光扫描系统进行既有铁路线路的勘测,研究如何利用三维点云数据自动、鲁棒的提取出轨顶面高程。首先... 详细信息

铁路轨顶面高程的精确获取对铁路的维护、改扩建工作至关重要。传统的测量方式存在安全性差、效率低、对运营干扰大等缺点。通过移动激光扫描系统进行既有铁路线路的勘测,研究如何利用三维点云数据自动、鲁棒的提取出轨顶面高程。首先结合设备定位定姿信息及仪器结构参数提取左右铁轨轨顶面中心线及左右轨的激光点云,然后将里程信息按一定间隔投影到左右轨中线。针对钢轨表面光滑造成的点云散乱问题,采用预先定义好的钢轨横断面几何模型进行匹配,循环计算以检测并剔除高程异常点或噪点,最终获取钢轨横断面几何模型顶部中心的高程,经过控制点辅助高程异常改正得到轨顶正常高。渝黔线某段的实测结果表明间隔60 m选取CPⅢ控制点进行约束时提取出的轨顶面高程中误差为4 mm,间隔800 m选取CPⅡ控制点约束时提取出的轨顶面高程中误差为9 mm,均满足规范要求。

关键词：既有线移动激光扫描系统点云轨顶高程

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

从信息获取角度研究网络信息资源共享机制

引用

图书情报工作 2009年第22期53卷 116-119页

作者：夏翠军广东外语外贸大学图书馆广州510420

分析信息资源共享的理论基础,通过产权设定改变信息资源的分配方式,直接影响到信息的获取模式,产生不同共享效果。然后从知识产权角度将信息资源分为公共领域信息、专有领域信息和部分著作权权利信息。最后从信息获取角度分别研究了三... 详细信息

分析信息资源共享的理论基础,通过产权设定改变信息资源的分配方式,直接影响到信息的获取模式,产生不同共享效果。然后从知识产权角度将信息资源分为公共领域信息、专有领域信息和部分著作权权利信息。最后从信息获取角度分别研究了三种类型信息资源的共享方式以及如何建立不同的共享机制。

关键词：信息获取网络信息资源共享公共领域信息完全著作权权利信息部分著作权权利信息

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：