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Effects of different concentrations of nicotinamide on hematopoietic stem cells cultured in vitro

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World Journal of Stem Cells 2024年第2期16卷 163-175页

作者： Yan Ren Yan-ni cui Hong-Wei Wang The Second Clinical Medical College Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Department of Hematology The Second Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Department of Hematology Key Laboratory of Molecular Diagnosis and Treatment of Blood Diseases in Shanxi ProvinceTaiyuan 030001Shanxi ProvinceChina

BACKGROUND In vitro expansion to increase numbers of hematopoietic stem cells(HSCs)in cord blood could improve clinical efficacy of this vital ***(NAM)can promote HSC expansion ex vivo,but its effect on hematopoietic stem and progenitor cells(HSPCs,CD34^(+)CD38)and functional subtypes of HSCs-shortterm repopulating HSCs(ST-HSCs,CD34^(+)CD38CD45RACD49f^(+))and long-term repopulating HSCs(LT-HSCs,CD34^(+)CD38CD45RACD49f^(+)CD90^(+))is not yet *** a sirtuin 1(SIRT1)inhibitor,NAM participates in regulating cell adhesion,polarity,migration,proliferation,and ***,SIRT1 exhibits dual effects by promoting or inhibiting differentiation in different tissues or *** propose that the concentration of NAM may influence proliferation,differentiation,and SIRT1 signaling of *** To evaluate the effects and underlying mechanisms of action of different concentrations of NAM on HSC proliferation and *** CD34^(+)cells were purified from umbilical cord blood using MacsCD34 beads,and cultured for 10-12 d in a serum-free medium supplemented with cytokines,with different concentrations of NAM added according to experimental *** cytometry was used to detect phenotype,cell cycle distribution,and apoptosis of the cultured ***-time polymerase chain reaction was used to detect the transcription levels of target genes encoding stemness-related factors,che mokines,components of hypoxia pathways,and antioxidant ***-dihydro-fluorescein diacetate probes were used to evaluate intracellular production of reactive oxygen species(ROS).Determination of the effect of different culture conditions on the balance of cytokine by cytometric bead *** Compared with the control group,the proportion and expansion folds of HSPCs(CD34^(+)CD38)incubated with 5 mmol/L or 10 mmol/L NAM were significantly increased(all Pnificantly

关键词： Hematopoietic stem cells nicotinamide Concentration Proliferation Differentiation Sirtuin 1

Vermiform ni@CNT derived from one-pot calcination of ni-MOF precursor for improving hydrogen storage of MgH_(2)

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Transactions of Nonferrous Metals Society of China 2024年第8期34卷 2629-2644页

作者： Zi-yin DAI Bing ZHANG Hideo KIMURA Li-rong XIAO Rong-han LIU cui ni Chuan-xin HOU Xue-qin SUN Yu-ping ZHANG Xiao-yang YANG Rong-hai YU Wei DU Xiu-bo XIE School of Environmental and Material Engineering Yantai UniversityYantai 264005China Key Laboratory of Aerospace Materials and Performance Ministry of EducationSchool of Materials Science and EngineeringBeihang UniversityBeijing 100191China

The ni-coated carbon nanotubes(ni@CNT)composite was synthesized by the facile“filtration+calcination”of ni-based metal−organic framework(MOF)precursor and the obtained composite was used as a catalyst for MgH_(2).MgH_(2)was mixed evenly with different amounts of ni@CNT(2.5,5.0 and 7.5,wt.%)through ball *** MgH_(2)−5wt.%ni@CNT can absorb 5.2 wt.%H_(2)at 423 K in 200 s and release about 3.75 wt.%H_(2)at 573 K in 1000 *** its dehydrogenation and rehydrogenation activation energies are reduced to 87.63 and 45.28 kJ/mol(H_(2)).The in-situ generated Mg_(2)ni/Mg_(2)niH4 exhibits a good catalytic effect due to the provided more diffusion channels that can be used as“hydrogen pump”.And the presence of carbon nanotubes improves the properties of MgH_(2)to some extent.

关键词： Mg-based hydrogen storage material activation energy ni-loaded carbon nanotubes catalyst mechanism

中国对“一带一路”沿线国家直接投资影响因素及投资潜力分析

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物流研究 2024年第1期 48-64页

作者：李翠妮河北大学河北保定071000

利用2005—2020年面板数据,对中国对“一带一路”沿线国家直接投资的影响因素及投资潜力进行实证研究。研究发现,从国家层面看,中国人均收入水平、技术创新水平、东道国劳动力规模、是否与中国有共同边界、经济自由度指数、双边贸易联... 详细信息

利用2005—2020年面板数据,对中国对“一带一路”沿线国家直接投资的影响因素及投资潜力进行实证研究。研究发现,从国家层面看,中国人均收入水平、技术创新水平、东道国劳动力规模、是否与中国有共同边界、经济自由度指数、双边贸易联系程度、是否与中国签订双边投资协定并生效、是否与中国签订自由贸易协定等因素均对中国投资“一带一路”沿线国家有积极促进作用;中国对“一带一路”沿线国家直接投资处于“投资不足”的状态,不同国家的投资潜力差异较大等。

关键词： “一带一路” 对外直接投资影响因素投资潜力

基于Dijkstra算法的平滑路径规划方法

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北京航空航天大学学报 2024年第2期50卷 535-541页

作者：巩慧倪翠王朋程诺山东交通学院信息科学与电气工程学院济南250357 山东省科学院自动化研究所济南250013

移动机器人在复杂环境下沿Dijkstra算法规划的路径运动时,由于所规划的路径存在转折点多、部分转折角度小等问题,导致移动机器人不得不频繁转向,甚至要暂停才能完成转向,严重影响机器人的工作效率。利用几何拓扑学方法,结合实际场景信息... 详细信息

移动机器人在复杂环境下沿Dijkstra算法规划的路径运动时,由于所规划的路径存在转折点多、部分转折角度小等问题,导致移动机器人不得不频繁转向,甚至要暂停才能完成转向,严重影响机器人的工作效率。利用几何拓扑学方法,结合实际场景信息,提出一种基于Dijkstra算法的平滑路径规划方法。根据应用场景获取连续化地图,将连续化地图离散化后随机生成离散点阵,计算各点之间的欧氏距离,选取与各离散点距离较近、且连线不跨越障碍的多个点,将其连接并生成离散图。在离散图中利用Dijkstra算法搜索最优路径作为引导路径。当移动机器人沿引导路径运动时,结合实际场景信息,采用几何拓扑学计算出移动机器人每一时刻应该采取的最佳动作和运行路线。实验结果表明:所提方法能够有效减少移动机器人运动中的累计转弯角度,增大最小平均转折角度,提高所规划路径的平滑度,从而缩短移动机器人的运动时间,提升机器人的工作效率。

关键词：路径规划 Dijkstra算法引导路径路径平滑度最优路径

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视觉SLAM方法综述

北京航空航天大学学报 2024年第2期50卷 359-367页

作者：王朋郝伟龙倪翠张广渊巩慧山东交通学院信息科学与电气工程学院济南250357 山东省科学院自动化研究所济南250013

实时定位与建图(SLAM)技术搭载特定传感器,使移动机器人在无任何环境先验条件下,在运动过程中自主建立环境模型来计算自身位姿,大幅提高其自主导航能力,以及对不同应用环境的适应性。视觉SLAM方法以相机作为外部传感器,通过采集周围环... 详细信息

实时定位与建图(SLAM)技术搭载特定传感器,使移动机器人在无任何环境先验条件下,在运动过程中自主建立环境模型来计算自身位姿,大幅提高其自主导航能力,以及对不同应用环境的适应性。视觉SLAM方法以相机作为外部传感器,通过采集周围环境信息来创建地图并实时估计机器人自身位姿。为此,介绍了具有代表性的经典视觉SLAM方法及与深度学习相结合的视觉SLAM方法,分析了视觉SLAM方法中采用的不同特征检测方法、后端优化、闭环检测,以及动态环境下视觉SLAM方法的应用,总结了视觉SLAM方法的问题,并探讨了视觉SLAM方法在未来的热点研究方向和发展前景。

关键词：视觉实时定位与建图深度学习特征检测位姿估计闭环检测

紧凑型水性B1B2工艺配套1K清漆的涂装性能研究及应用

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现代涂料与涂装 2024年第8期27卷 28-30+33页

作者：尤永崔春妮潘丽娜安徽江淮汽车集团股份有限公司技术中心陕西省产品质量监督检验研究院

重点介绍了紧凑型水性B1B2工艺配套1 K清漆的涂装性能，主要从1K清漆和2K清漆的成膜机理、涂膜外观性能、涂膜抗擦伤性能、老化性能等方面进行了对比验证分析。结果表明：水性B1B2工艺配套1K清漆工艺的涂膜性能与配套2 K清漆工艺的涂膜... 详细信息

重点介绍了紧凑型水性B1B2工艺配套1 K清漆的涂装性能，主要从1K清漆和2K清漆的成膜机理、涂膜外观性能、涂膜抗擦伤性能、老化性能等方面进行了对比验证分析。结果表明：水性B1B2工艺配套1K清漆工艺的涂膜性能与配套2 K清漆工艺的涂膜性能存在差距，但配套1 K清漆在成本等方面具有一定的优势。

关键词： B1B2工艺 1K清漆 2K清漆涂装性能

Recent advances in the nanoconfinement of Mg-related hydrogen storage materials:A minor review

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International Journal of Minerals,Metallurgy and Materials 2023年第1期30卷 14-24页

作者： Jingjing Zhang Bing Zhang Xiubo Xie cui ni Chuanxin Hou Xueqin Sun Xiaoyang Yang Yuping Zhang Hideo Kimura Wei Du School of Environmental and Material Engineering Yantai UniversityYantai 264005China

Hydrogen is an ideal clean energy because of its high calorific value and abundance of ***,storing hydrogen in a compact,inexpensive,and safe manner is the main restriction on the extensive utilization of hydrogen ***(Mg)-based hydrogen storage material is considered a reliable solid hydrogen storage material with the advantages of high hydrogen storage capacity(7.6wt%),good performance,and low ***,the high thermodynamic stability and slow kinetics of Mg-based hydrogen storage materials have to be *** this paper,we will review the recent advances in the nanoconfinement of Mg-related hydrogen storage materials by loading Mg particles on different supporting materials,including carbons,metal-organic frameworks,and other *** are also provided for designing high-performance Mg-based materials using nanoconfinement.

关键词： magnesium-based materials hydrogen storage nanoconfinement carbon materials

Multiple “Omics” data-based biomarker screening for hepatocellular carcinoma diagnosis

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World Journal of Gastroenterology 2019年第30期25卷 4199-4212页

作者： Xiao-Na Liu Dan-ni cui Yu-Fang Li Yun-He Liu Gang Liu Lei Liu Institutes of Biomedical Sciences Fudan University

The huge prognostic difference between early and late stage hepatocellular carcinoma(HCC)is a challenging diagnostic ***-fetoprotein is the mostly widely used biomarker for HCC used in the clinic,however it’s sensitivity and specificity of is not *** development and application of multiple biotechnologies,including next generation sequencing,multiple“omics”data,that include genomics,epigenomics,transcriptomics,proteomics,metabolomics,metagenomics has been used for HCC diagnostic biomarker *** biomarkers/panels/models have been identified and validated at different clinical levels.A large proportion of these have a good diagnostic performance for HCC,especially for early *** this article,we reviewed the various HCC biomarkers derived from“omics”data and discussed the advantages and disadvantages for diagnosis HCC.

关键词： Hepatocellular carcinoma Diagnosis Circulating tumor cells Exosomes Circulating tumor DNA RNA Metabolomics Protein

Larval Descriptions of Three Species of Epipaschiinae(Lepidoptera: Pyralidae) from China

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Entomotaxonomia 2008年第4期30卷 273-279页

作者：朴美花倪翠侠中国计量学院生命科学学院浙江杭州310018

The last-instar larval external morphologies of Orthaga achatina Butler, Macalla sp. and Locastra muscosalis （Walker） of Epipaschiinae are described and illustrated. All specimens examined are deposited in the Collection of College of Life Sciences, China Jiliang University, China. Biological information such as living habit also is included.

关键词： Lepidoptera Pyralidae Epipaschiinae larval morphology China