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Physio-chemical modeling of the NO_(x)-O_(3) photochemical cycle and the air pollutants’ reactive dispersion around an isolated building

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建筑模拟(英文) 2023年第9期16卷 1735-1758页

作者： yunfei Fu Xisheng lin Xing Zheng liangzhu Wang Chun-Ho liu Xuelin Zhang cruz y.li K.T.Tse Department of Civil and Environmental Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina Future Cities Lab Global Singapore-ETH CentreSingapore 138602 Department of Building Civil and Environmental Engineering at Concordia UniversityMontrealQuebecCanada Department of Mechanical Engineering The University of Hong KongPok-fu-lam RoadHong KongChina Department of Civil Engineering Chongqing UniversityChongqingChina School of Atmospheric Sciences Sun Yat-sen UniversityZhuhaiChina

A numerical physio-chemical model of the NO_(x)-O_(3) photochemical cycle in the near-wake region of an isolated residential/office building has been presented in this *** investigation delves into the dispersion of reactive air pollutants through the lens of fluid phenomenology and its impact on chemical reactivity,formation,transport,deposition,and *** fluid dynamics(CFD)simulations were conducted for the ground-point-source(GES)and roof-pointsource(RES)*** show that the Damköhler number(Da),which quantifies pollutants’physio-chemical timescales,displays a strong inverse proportionality with the magnitude and spread of NO–increasing Da reduces human exposure to the toxic NO and NO_(2) *** different wind directions were considered,the dispersion range of NO exhibited varying shrinking directions as Da ***,as Da increases,the concentration ratio KNO_(2)/KNO_(x),which quantifies the production of NO_(2) resulting from NO depletion,forms sharp high-low gradients near emission *** GES,the dispersion pattern is governed by the fluid’s phenomenological *** RES,the intoxicated area emanates from the building’s leading-edge,with the lack of shielding inhibiting pollutant interactions in the near-wake,resulting in scant physio-chemical *** NO_(2)/NO_(x) distribution follows a self-similar,stratified pattern,exhibiting consistent layering gradients and attributing to the natural deposition of the already-reacted pollutants rather than in-situ *** the end,building design guidelines have been proposed to reduce pedestrian and resident exposure to NO_(x)-O_(3).

关键词： reactive pollutant dispersion NO_(x)-O_(3)cycle air pollution isolated building physio-chemical modelling

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Occupational physical activity, all-cause, cardiovascular disease, and cancer mortality in 349,248 adults: Prospective and longitudinal analyses of the MJ Cohort

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Journal of Sport and Health Science 2024年第4期13卷 579-589页

作者： Emmanuel Stamatakis Matthew N.Ahmadi Tiana-Lee Elphick Bo-Huei Huang Susan Paudel Armando Teixeira-Pinto li-Jung Chen Borja del Pozo cruz yun-Ju Lai Andreas Holtermann Po-Wen Ku Sydney School of Health Sciences Faculty of Medicine and HealthCharles Perkins CentreUniversity of SydneySydneyNSW 2006Australia Sydney School of Public Health Faculty of Medicine and HealthUniversity of SydneySydneyNSW 2006Australia Department of Exercise Health Science “National”Taiwan University of SportTaichung 40404China Department of Sports Science and Clinical Biomechanics University of Southern DenmarkOdense 5230Denmark Division of Endocrinology and Metabolism Department of Internal MedicinePuli Branch of Taichung Veterans General HospitalNantou 54552China National Research Centre for the Working Environment Copenhagen 2100Denmark Graduate Institute of Sports and Health Management “National”Chung Hsing UniversityTaichung 40227China

Background:Evidence on the health benefits of occupational physical activity(OPA)is *** examined the associations of baseline OPA and OPA changes with all-cause,cardiovascular disease(CVD),and cancer mortality and survival ***:This study included prospective and longitudinal data from the MJ Cohort,comprising adults over 18 years recruited in 1998-2016,349,248 adults(177,314 women)with baseline OPA,of whom 105,715(52,503 women)had 2 OPA measures at 6.3±4.2 years(mean±SD)*** were baseline OPA,OPA changes,and baseline leisure-time physical ***:Over a mean mortality follow-up of 16.2±5.5 years for men and 16.4±5.4 years for women,11,696 deaths(2033 of CVD and 4631 of cancer causes)in men and 8980 deaths(1475 of CVD and 3689 of cancer causes)in women *** moderately heavy/heavy baseline OPA was beneficially associated with all-cause mortality in men(multivariable-adjusted hazard ratio(HR)=0.93,95%confidence interval(95%CI):0.89-0.98 compared to light OPA)and women(HR=0.86,95%CI:0.79-0.93).Over a mean mortality follow-up of 12.5±4.6 years for men and 12.6±4.6 years for women,OPA decreases in men were detrimentally associated(HR=1.16,95%CI:1.01-1.33)with all-cause mortality,while OPA increases in women were beneficially(HR=0.83,95%CI:0.70-0.97)associated with the same *** or changes in OPA showed no associations with CVD or cancer ***:Higher baseline OPA was beneficially associated with all-cause mortality risk in both men and *** longitudinal OPA analyses partly confirmed the prospective findings,with some discordance between sex groups.

关键词： Cancer Cardiovascular disease Epidemiology Mortality

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Study of tree shrew biology and models: A booming and prosperous field for biomedical research

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Zoological Research 2024年第4期45卷 877-909页

作者： yong-Gang yao li Lu Rong-Jun Ni Rui Bi Ceshi Chen Jia-Qi Chen Eberhard Fuchs Marina Gorbatyuk Hao Lei Hongli li Chunyu liu Long-Bao Lv Kyoko Tsukiyama-Kohara Michinori Kohara Claudia Perez-cruz Gregor Rainer Bao-Ci Shan Fang Shen An-Zhou Tang Jing Wang Wei Xia Xueshan Xia ling Xu Dandan yu Feng Zhang Ping Zheng yong-Tang Zheng Jumin Zhou Jiang-Ning Zhou Key Laboratory of Genetic Evolution and Animal Models Yunnan Key Laboratory of Animal Models and Human Disease MechanismsKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650204China National Research Facility for Phenotypic&Genetic Analysis of Model Animals(Primate Facility) and National Resource Center for Non-Human PrimatesKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650107China KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650204China Kunming College of life Science University of Chinese Academy of SciencesKunmingYunnan 650204China Mental Health Center and Psychiatric Laboratory West China HospitalSichuan UniversityChengduSichuan 610041China Sichuan Clinical Medical Research Center for Mental Disorders ChengduSichuan 610044China German Primate Center Leibniz Institute of Primate ResearchGöttingen 37077Germany Department of Optometry and Vision Science School of OptometryUniversity of Alabama at BirminghamBirminghamAL 35294USA State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Innovation Academy for Precision Measurement Science and TechnologyChinese Academy of SciencesWuhanHubei 430071China Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhanHubei 430074China Soong Ching ling Institute of Maternity and Child Health International Peace Maternity and Child Health HospitalShanghai Jiao Tong University School of MedicineShanghai 200030China Transboundary Animal Diseases Center Joint Faculty of Veterinary MedicineKagoshima UniversityKagoshima-cityKagoshima 890-8580Japan Department of Microbiology and Cell Biology Tokyo Metropolitan Institute of Medical ScienceTokyo 156-8506Japan Pharmacology Department CinvestavMexico City 07360Mexico Department of Medicine University of FribourgFribourg CH-1700Switzerland Beijing Engineering Research Center of Radiog

The tree shrew(Tupaia belangeri)has long been proposed as a suitable alternative to non-human primates(NHPs)in biomedical and laboratory research due to its close evolutionary relationship with *** recent years,significant advances have facilitated tree shrew studies,including the determination of the tree shrew genome,genetic manipulation using spermatogonial stem cells,viral vector-mediated gene delivery,and mapping of the tree shrew brain ***,the limited availability of tree shrews globally remains a substantial challenge in the ***,determining the key questions best answered using tree shrews constitutes another *** shrew models have historically been used to study hepatitis B virus(HBV)and hepatitis C virus(HCV)infection,myopia,and psychosocial stress-induced depression,with more recent studies focusing on developing animal models for infectious and neurodegenerative *** these efforts,the impact of tree shrew models has not yet matched that of rodent or NHP models in biomedical *** review summarizes the prominent advancements in tree shrew research and reflects on the key biological questions addressed using this *** emphasize that intensive dedication and robust international collaboration are essential for achieving breakthroughs in tree shrew *** use of tree shrews as a unique resource is expected to gain considerable attention with the application of advanced techniques and the development of viable animal models,meeting the increasing demands of life science and biomedical research.

关键词： Tree shrew Animal model Neurodegenerative diseases Infectious diseases Neuroscience Phenome

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Enhanced fluorescence sensing of tetracy.line with Ti_(2)C quantum dots

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Nano Research 2024年第4期17卷 3180-3188页

作者： Dejia Hu ShangZuo Jiang Tianhao Xia Danyang Xiao yan li yanbing Hou Jin Zhong Zhang ying-Chih Pu School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China Key Lab Luminescence&Optical Information Ministry EducationBeijing JiaoTong UniversityBeijing 100044China Department of Chemistry and Biochemistry University of CaliforniaSanta CruzCalifornia 95064USA Department of Materials Science "National University of Tainan"Tainan 700301TaiwanChina

Ti_(2)C quantum dots(QDs)with rich surface functional groups have been synthesized using a hydrothermal method,and used to detect tetracy.line(Tc)based on enhanced *** interaction between the surface functional groups of Ti_(2)C QDs and Tc enhanced the fluorescence of Tc at 514 nm,which is used to detect Tc quickly and *** optimal conditions,the fluorescence intensity was linear to the concentration of Tc in the range of 50.0–30.0μM,with a detection limit of 21.6 ***,the Tc-Ti_(2)C QDs detection system was evaluated for detection of Tc in milk and artificial *** study demonstrates a new and simple strategy for Tc detection,which is important for food safety and human health.

关键词： Ti_(2)C MXene quantum dots tetracy.line fluorescence enhancement detection

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Towards efficient strain engineering of 2D materials:A four-points bending approach for compressive strain

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Nano Research 2024年第6期17卷 5317-5325页

作者： Hao li Félix Carrascoso Ana Borrás Gloria P.Moreno Francisco J.Aparicio Ángel Barranco Andrés Castellanos Gómez Campus de Cantoblanco Instituto de Ciencia de Materiales de MadridC.Sor Juana Inés de la Cruz328049 MadridSpain Nanotechnology on Surfaces and Plasma Lab Instituto de Ciencia de Materiales de Sevilla(CSIC-Universidad de Sevilla).C/Americo Vespucio 49E-41092 SevilleSpain Departamento de Física Aplicada I Escuela Politécnica SuperiorUniversidad de Sevillac/Virgen deÁfrica 7E-41011 SevilleSpain

Strain engineering,as a powerful strategy to tune the optical and electrical properties of two-dimensional(2D)materials by deforming their crystal lattice,has attracted significant interest in recent years.2D materials can sustain ultra-high strains,even up to 10%,due to the lack of dangling bonds on their surface,making them ideal brittle *** remarkable mechanical resilience,together with a strong strain-tunable band structure,endows 2D materials with a broad optical and electrical response upon ***,strain engineering based on 2D materials is restricted by their nanoscale and strain quantification *** this study,we have modified a homebuilt three-points bending apparatus to transform it into a four-points bending apparatus that allows for the application of both compressive and tensile strains on 2D *** approach allows for the efficient and reproducible construction of a strain system and minimizes the buckling effect caused by the van der Waals interaction by adamantane encapsulation *** results demonstrate the feasibility of introducing compressive strain on 2D materials and the potential for tuning their optical and physical properties through this approach.

关键词： uniaxial compressive strain polymer encapsulation differential reflectance spectroscopy exciton tunability

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Virus-Host Interactions Drive Contrasting Bacterial Diel Dynamics in the Ocean

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Research 2024年第2期6卷 389-399页

作者： Xiaowei Chen Chen Hu Wei Wei yunlan yang Markus G.Weinbauer Hongbo li Shiying Ren Ruije Ma yVibin Huang Tingwei Luo Nianzhi Jiao Rui Zhang State Key Laboratory of Marine Environmental Science College of Ocean and Earth SciencesFujian Key Laboratory of Marine Carbon SequestrationXiamen UniversityXiamen 361102PR China College of the Environment and Ecology Xiamen UniversityXiamen 361102PR China Research Center for Environmental Ecology and Engineering School of Environmental Ecology and Biological EngineeringWuhan Institute of TechnologyWuhan 430205PR China Sorbonne Universités UPMCUniversitéParis 06CNRSLaboratoire d'Oceanographie de Villefranche(LOV)Villefranche-sur-Mer 06230France National Marine Environmental Monitoring Center Ministry of Ecological EnvironmentDalian 116023PR China Department of Ocean Sciences University of CaliforniaSanta CruzCAUSA NOAA/OAR Pacific Marine Environmental Laboratory SeattleWAUSA Institute for Advanced Study Shenzhen UniversityShenzhen 518055PR China

Marine organisms perform a sea of diel *** diel dynamics have been shown to be driven by.light,energy resources,circadian rhythms,and the coordinated coupling of photoautotrophs and heterotrophic ***,we explore the diel fluctuation of viral production and decay and their impact on the total and active bacterial community in the coastal and open seawaters of the South China *** results showed that the night-production diel pattern of lytic viral production was concurrent with the lower viral decay at night,contributing to the accumulation of the viral population size during the night for surface *** diel variations in bacterial activity,community composition,and diversity were found highly affected by viral *** was revealed by the finding that bacterial community diversity was positively correlated to lytic viral production in the euphotic zone of the open ocean but was negatively related to lysogenic viral production in the coastal *** distinct but contrasting correlations suggest that viral life strategies can not only contribute to diversifying bacterial community but also potentially piggyback their host to dominate bacterial community,suggesting the tightly synchronized depth-dependent and habitat-specific diel patterns of virus-host *** further implies that viruses serve as an ecologically important driver of bacterial diel dynamics across the ocean,highlighting the viral roles in bacterial ecological and biogeochemical processes in the ocean.

关键词： coastal ocean Marine

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A controlled random gene perturbation method identifies ARPC1B gene as a key regulator of cancer metastasis

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Genes & Diseases 2023年第3期10卷 687-689页

作者： De Chang Hongzhen Du Xiaowei Chen Xiaocui Bian Wenjia Tian Jing Shen yiju Wei yunpeng Jiang Charles Dela cruz lixin Xie Lokesh Sharma Kailong li College of Pulmonary and Critical Care Medicine Chinese PLA General HospitalBeijing 100083China Institute of Basic Medical Sciences Chinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical CollegeBeijing 100005China Section of Pulmonary and Critical Care and Sleep Medicine Department of MedicineYale University School of MedicineNew HavenCT 06520USA Department of Biochemistry and Biophysics Peking University Health Science CenterBeijing 100191China

The discovery of clinically useful targets to treat specific pathological conditions can provide novel therapeutic *** unbiasedly identify key genes related to tumor metastasis,we developed a random gene perturbation method using a piggyBac transposon system under the control of a doxycy.line regulated *** this random gene perturbation method and utilizing a mouse model of metastatic pancreatic cancer,we identified genes dysregulated in metastasized cells from a random mutagenesis library after multiple rounds of in vivo *** of these metastasized clones revealed the downregulation of ARPC1B *** further mechanistic studies revealed that ARPC1B gene and its closely related gene ARPC1A worked in a regulatory loop to control tumor *** findings validate that piggyBac transposon mediated random gene perturbation is a powerful tool to investigate the functional relevance of novel genes and the ARPC1A/B axis is a potential key regulator of tumor metastasis.

关键词： metastasis cancer random

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Towards an actionable One Health approach

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贫困所致传染病(英文) 2024年第2期13卷 77-82页

作者： Zhang Xiao-Xi Lederman Zohar Han Le-Fei Schurer Janna M. Xiao li-Hua Zhang Zhi-Bing Chen Qiu-Lan Pfeiffer Dirk Ward Michael P. Sripa Banchob Gabri?l Sarah Dhama Kuldeep Acharya Krishna Prasad Robertson Lucy J. Deem Sharon L. Aenishaenslin Cécile Dantas-Torres Filipe Otranto Domenico Grace Delia Wang yang li Peng Fu Chao Poeta Patrícia Rahman Md. Tanvir Kassegne Kokouvi Zhu yong-Zhang yin Kun liu Jiming Wang Zhao-Jun Guo Xiao-Kui Gong Wen-Feng Schwartl?nder Bernhard Ren Ming-Hui Zhou Xiao-Nong Sydney School of Veterinary Science The University of Sydney Camden Australia Tropical Disease Research Center Department of Tropical Medicine Faculty of Medicine Khon Kaen University Khon Kaen Thailand Laboratory of foodborne parasitic zoonoses Department of translational physiology infectiology and public health Chair Faculty Committee on Internationalisation Faculty of Veterinary Medicine Ghent University Merelbeke Belgium Division of Pathology ICAR-Indian Veterinary Research Institute (IVRI) Bareilly Uttar Pradesh India Department of livestock Services Animal Quarantine Office-Kathmandu Budhanilkantha Kathmandu Nepal Parasitology Department of Paraclinical Sciences Faculty of Veterinary Medicine Norwegian University of Life Sciences ?s Norway One Government Drive Saint Louis Zoo Institute for Conservation Medicine St. Louis USA Groupe de Recherche en épidémiologie des Zoonoses et Santé Publique (GREZOSP) Faculté de médecine vétérinaire Université de Montréal Saint-Hyacinthe Québec Canada Centre de recherche en santé publique de l Université de Montréal et du CIUSSS du Centre-Sud-de-l’?le-de-Montréal Montréal Québec Canada Department of Immunology Aggeu Magalh?es Institute Oswaldo Cruz Foundation (Fiocruz) Recife Brazil School of Global Health Chinese Center for Tropical Diseases Research Shanghai Jiao Tong University School of Medicine Shanghai People’s Republic of China Department of Veterinary Medicine University of Bari Valenzano Italy Department of Pathobiology Faculty of Veterinary Science Bu-Ali Sina University Hamedan Iran Natural Resources Institute University of Greenwich Chatham Maritime UK International livestock Research Institute Nairobi Kenya Director of Key Laboratory of Animal Antimicrobial Resistance Surveillance Ministry of Agriculture and Rural Affairs Beijing People’s Republic of China Institute of Animal Science Chinese Academy of Agricultural Sciences Beijing People’s Republic of China Key Laboratory of Ecosystem Network O

Background Despite the increasing focus on strengthening One Health capacity building on global level, challenges remain in devising and implementing real-world interventions particularly in the Asia-Pacific region. Recognizing these gaps, the One Health Action Commission (OHAC) was established as an academic community for One Health action with an emphasis on research agenda setting to identify actions for highest *** text This viewpoint describes the agenda of, and motivation for, the recently formed OHAC. Recognizing the urgent need for evidence to support the formulation of necessary action plans, OHAC advocates the adoption of both bottom-up and top-down approaches to identify the current gaps in combating zoonoses, antimicrobial resistance, addressing food safety, and to enhance capacity building for context-sensitive One Health *** By promoting broader engagement and connection of multidisciplinary stakeholders, OHAC envisions a collaborative global platform for the generation of innovative One Health knowledge, distilled practical experience and actionable policy advice, guided by strong ethical principles of One Health.

关键词： One Health Global Health One Health Action Commission Research agenda

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TiN Paper for Ultrafast-Charging Supercapacitors

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Nano-Micro Letters 2020年第1期12卷 27-39页

作者： Bin yao Mingyang li Jing Zhang Lei Zhang yu Song Wang Xiao Andrea cruz yexiang Tong yat li Department of Chemistry and Biochemistry University of CaliforniaSanta CruzSanta CruzCA 95064USA KLGHEI of Environment and Energy Chemistry MOE of the Key Laboratory of Bioinorganic and Synthetic ChemistrySchool of Chemistry and Chemical EngineeringSun Yat-Sen UniversityGuangzhou 510275People’s Republic of China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070People’s Republic of China

Ultrafast-charging energy storage devices are attractive for powering personal electronics and electric *** ultrafast-charging devices are made of carbonaceous materials such as chemically converted graphene and carbon ***,their relatively low electrical conductivity may restrict their performance at ultrahigh charging ***,we report the fabrication of a porous titanium nitride(TiN)paper as an alternative electrode material for ultrafast-charging *** TiN paper shows an excellent conductivity of 3.67×104 S m−1,which is considerably higher than most carbon-based *** paper-like structure also contains a combination of large pores between interconnected nanobelts and mesopores within the *** unique electrode enables fast charging by simultaneously providing efficient ion diffusion and electron *** supercapacitors(SCs)made of TiN paper enable charging/discharging at an ultrahigh scan rate of 100 V s−1 in a wide voltage window of 1.5 V in Na2SO4 neutral *** has an outstanding response time with a characteristic time constant of 4 ***,the TiN paper-based SCs also show zero capacitance loss after 200,000 cycles,which is much better than the stability performance reported for other metal nitride ***,the device shows great promise in *** filtration method enables good control of the thickness and mass loading of TiN electrodes and devices.

关键词： Ultrafast charging Wide voltage window TiN Paper-like electrode Supercapacitors

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A review of recent research progress on the effect of external influences on tropical cyclone intensity change

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Tropical Cyclone Research and Review 2023年第3期12卷 200-215页

作者： Joshua B.Wadler Johna E.Rudzin Benjamin Jaimes de la cruz Jie Chen Michael Fischer Guanghua Chen Nannan Qin Brian Tang Qingqing li Embry-Riddle Aeronautical University Department of Applied Aviation SciencesDaytona BeachFLUSA Mississippi State University Department of GeosciencesStarkvilleMSUSA University of Miami Department of Ocean SciencesMiamiFLUSA Princeton University Atmospheric and Oceanic Sciences ProgramPrincetonNJUSA University of Miami Cooperative Institute for Marine and Atmospheric Studies and NOAAAtlantic Oceanographic and Meteorological LaboratoryHurricane Research DivisionMiamiFLUSA Institute of Atmospheric Physics of the Chinese Academy of Sciences BeijingChina Key Laboratory of Transportation Meteorology of China Meteorological Administration Nanjing Joint Institute for Atmospheric SciencesNanjingChina University at Albany State University of New YorkDepartment of Atmospheric and Environmental SciencesAlbanyNYUSA Nanjing University of Information and Science Technology NanjingChina

Over the past four years,signiﬁcant research has advanced our understanding of how external factors inﬂuence tropical cyclone(TC)intensity *** on air-sea interactions shows that increasing the moisture disequilibrium is a very effective way to increase surface heatﬂuxes and that ocean salinity-stratiﬁcation plays a non-negligible part in TC intensity *** wind shear from the environment induces vortex misalignment,which controls the onset of signiﬁcant TC intensiﬁ*** due to upper-level outﬂow from TCs can reduce the magnitude of vertical wind shear,making for TC intensiﬁ*** TC-trough interactions are vital for rapid intensiﬁcation in some TC cases because of strengthened warm air advection,but upper-level troughs are found to limit TC intensiﬁcation in other cases due to dry midlevel air intrusions and increased *** effects on TCs can be divided into direct effects involving aerosol-radiation interactions and indirect effects involving aerosol-cloud *** radiation absorption by the aerosols can change the temperature proﬁle and affect outer rainbands through changes in stability and *** spray and sea salt aerosols are more important in the inner region,where the aerosols increase precipitation and latent heating,promoting more intensiﬁ*** landfalling TCs,the intensity decay is initially more sensitive to surface roughness than soil moisture,and the subsequent decay is mainly due to the rapid reduction in surface moistureﬂ*** new insights further sharpen our understanding of the mechanisms by which external factors inﬂuence TC intensity changes.

关键词： Tropical cyclone External inﬂuence Intensity change Review

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