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Kainate receptors in the CA2 region of the hippocampus

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Neural Regeneration Research 2023年第2期18卷 320-321页

作者： Yuniesky Andrade-talavera Antonio Rodríguez-Moreno Laboratorio de Neurociencia Celulary Plasticidad Departamento de FisiologíaAnatomía y Biología CelularUniversidad Pablo de OlavideSevillaSpain

The hippocampus is involved in important brain functions such as learning and memory,spatial navigation,fear processing,and social behavior(Dudek et al,2016).The most prominent areas of the hippocampus are typically denoted as the dentate gyrus and the three areas of the cornu ammonis(CA1,CA2,and CA3).Discovered by Lorente de Nó(1934),the CA2 region of the hippocampus is a relatively small area interposed between CA3 and CA1 that forms the nexus linking the input of the entorhinal cortex to the output of CA1(Chevaleyre and Siegelbaum,2010).

关键词： CA2 cortex linking

Evolution of laparoscopic gastrectomy for cancer in the East and West

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Chinese Journal of Cancer Research 2022年第6期34卷 579-586页

作者： Eider talavera-Urquijo Bas P.L.Wijnhoven Department of Surgery University Hospital of DonostiaDonostia-San Sebastian 20014Spain Department of Surgery Erasmus University Medical Centre RotterdamRotterdam 3000the Netherlands

Laparoscopic gastrectomy has evolved differently in Eastern and Western ***,safety and oncological outcomes of laparoscopic gastrectomy were addressed step-by-step by several randomized controlled trials from the *** phase III studies were published from the West that largely did not show a difference between the laparoscopic and open *** this,laparoscopic gastrectomy is seen as the standard for the surgical treatment of early and advanced gastric cancer in many European ***,we review and comment on some important studies on laparoscopic gastrectomy for gastric cancer from Eastern and Western countries and also comment on current and future challenges.

关键词： Laparoscopic gastrectomy minimally invasive surgery gastric cancer

Sexual signal conspicuity is correlated with tail autotomy in an anoline lizard

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Current Zoology 2022年第1期68卷 129-132页

作者： Kelly LinWUTHRICH Derek STOCK Janelle B.talavera Breanna J.PUTMAN Lindsey SWIERK Department of Biological Sciences Binghamton UniversityState University of New YorkBinghamtonNY 13902USA Department of Biology California State UniversityNorthridgeCA 91330-8303USA Department of Biology California State UniversitySan BernardinoCA 92407USA Department of Ecology and Evolutionary Biology University of California621 Young Drive SouthLos AngelesCA 90095-1606USA Department of Herpetology and Urban Nature Research Center Natural History Museum of Los Angeles CountyLos AngelesCA 90007USA School of Forestry and Environmental Studies Yale UniversityNew HavenCT 06511USA Amazon Conservatory for Tropical Studies IquitosLoreto 16001Peru The Morpho Institute Kansas CityMO 64113USA

Sexual selection favors conspicuous signals that animals can use to communicate with conspecifics and/or to attract ***,natural and sexual selection are often in opposition,as conspicuous sexual signals can also be detected by eavesdropping predators,forcing these signals to also evolve in light of natural selection(Andersson 1994).

关键词： signal evolve selection

Narrow versus broad:sexual dimorphism in the wing form of western European species of the subgenus Avaritia(Culicoides,Ceratopogonidae)

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Integrative Zoology 2021年第5期16卷 769-784页

作者： Francesc MUÑOZ-MUÑOZ Nonito PAGÈS Ana.F.DURAO Marion ENGLAND Doreen WERNER Sandra talavera Departament de Biologia Animal de Biologia Vegetal i d’EcologiaFacultat de BiociènciesUniversitat Autònoma de BarcelonaBarcelonaSpain Centre de Recerca en Sanitat Animal(CReSA) UAB-IRTACampus de la Universitat Autònoma de BarcelonaBarcelonaSpain CIRAD UMR ASTREGuadeloupeFrance ASTRE CIRADINRAeUniversitéde MontpellierMontpellierFrance The Pirbright Institute SurreyUK Leibniz-Centre for Agricultural Landscape Research MünchebergGermany

While wing form is known to differ between males and females of the genus Culicoides,detailed studies of sexual dimorphism are *** this study,we analyze sex-specific differences in the wing form of 5 species of the subgenus Avaritia,using geometric morphometrics and comparative phylogenetic *** results confirm the existence of marked sexual dimorphism in the wing form of the studied species and reveal for the first time that while there is a shared general pattern of sexual shape dimorphism within the subgenus,sexual size dimorphism,and particular features of sexual shape dimorphism differ among *** shape dimorphism was found to be poorly associated to size and the evolutionary history of the *** tight association of sexual shape dimorphism with aspect ratio suggests that the shape of the wing is optimized for the type of flight of each sex,that is,dispersal flight in females versus aerobatic flight in ***,the fact that interspecific shape differences are greater and more strongly associated to aspect ratio in males than in females might be indicating that in males the selective pressures affecting flight performance characteristics are more heterogeneous and/or stronger than in females among the studied species.

关键词： aspect ratio geometric morphometrics phylogenetic signal shape size

Effect of inductively coupled plasma surface treatment on silica gel and mesoporous MCM-41 particles

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Plasma Science and Technology 2018年第6期20卷 104-113页

作者： J A JUAREZ-MORENO U CHACON-ARGAEZ J BARRON-ZAMBRANO C CARRERA-FIGUEIRAS P QUINTANA-OWEN W talavera-PECH Y PEREZ-PADILLA A AVILA-ORTEGA facultad de ingeniería química-uady periférico norte kilómetro 33.5col.chuburna de hidalgo inn C.P. 97203 Mérida Yucatan México centro de investigación y de estudios avanzados del ipn-unidad mérida km.6 antigua carretera a progreso apdo. Postal 73 Cordemex 97310 Méfida Yucatán México

Silica gel and MCM-41 synthesized mesoporous materials were treated with either oxygen（O_2）,hexamethyldisiloxane（HMDSO） and organic vapors like ethanol（Et OH）,and acrylonitrile（AN）inductive *** radiofrequency power for the modification was fixed to 120 W and30 min,assuring a high degree of organic ionization energy in the *** surface properties were studied by infrared spectroscopy（FTIR）,scanning electron microscopy,x-ray photoelectron spectroscopy and dynamic light scattering technique was used for characterizing size *** the silica and MCM-41 particles were modified by AN and HMDSO plasma gases,the surface morphology of the particles was changed,presenting another color,size or *** contrast,the treatments of oxygen and Et OH did not affect the surface morphology of both particles,but increased the oxygen content at the surface bigger than the AN and HMDSO plasma *** this study,we investigated the influence of different plasma treatments on changes in morphology and the chemical composition of the modified particles which render them a possible new adsorbent for utilization in sorptive extraction techniques for polar compounds.

关键词： silica MCM-41 nanoparticles plasma treatment

Screening chloroplast regions in Calophyllum brasiliense (Calophyllaceae) for suitability for population genetic analyses

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Journal of Forestry Research 2018年第4期29卷 978-985页

作者： Cecilia B. Percuoco Lucas G. Gimenez Liliana N. talavera Stefani Jorge V. Crisci Carina F. Argüelles Laboratorio GIGA Instituto de Biologia Subtropical Nodo Posadas Universidad Nacional de Misiones (UNaM) Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET) Jujuy 1745 N3300NFK Posadas Misiones Argentina Catedra de Genetica Molecular Facultad de Ciencias Exactas Quimicas y Naturales (FCEQyN) Universidad Nacional de Misiones (UNaM) Felix de Azara 1552 N3300LQH Posadas Misiones Argentina Laboratorio de Sistematica y Biologia Evolutiva (LASBE) Facultad de Ciencias Naturales y Museo (FCNyM) Universidad Nacional de La Plata-(UNLP) Avenida 122 y 60 1900 La Plata Buenos Aires Argentina

The uniparental inheritance and conserved structure of the chloroplast genome among many angiosperms makes it suitable for constructing gene lineages and inferring population histories based on these relationships. However, the analysis of a single chloroplast region to solve population issues has not yielded the desired amount of variability due to the low mutation rate. Therefore, it is necessary to screen and carefully analyze chloroplast intergenic or intronic regions to select the most appropriate for studying the genetic variability in the chloroplast genome of a particular taxon. In this context, the aim of this work was to characterize 8 regions in Calophyllum brasiliense using 11 selected primer pairs and to evaluate their usefulness for phylogeographic analysis. Intergenic spacers petA-psbJ, petG-trnP and rp132-trnL and the trnL intron demonstrated potentially informative sites. The combination of these 4 regions will allow the analysis of genetic population structure and the integration of historical aspects to inform strategies for conserving C. brasiliense, especially for highly impacted populations and those at risk of local extinction.

关键词： cpDNA cpSSRs Noncoding regions

Endothelium-derived essential signals involved in pancreas organogenesis

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World Journal of Experimental Medicine 2015年第2期5卷 40-49页

作者： Dodanim talavera-Adame Donald C Dafoe Comprehensive Transplant Center Department of Surgery Cedars-Sinai Medical Center Board of Governors Regenerative Medicine Institute Cedars-Sinai Medical Center

Endothelial cells(ECs) are essential for pancreas differentiation, endocrine specification, and endocrine function. They are also involved in the physiopathology of type 1 and type 2 diabetes. During embryogenesis, aortic ECs provide specific factors that maintain the expression of key genes for pancreas development such as pancreatic and duodenal homeobox-1. Other unknown factors are also important for pancreatic endocrine specification and formation of insulin-producing beta cells. Endocrine precursors proliferate interspersed with ductal cells and exocrine precursors and, at some point of development, these endocrine precursors migrate to pancreatic mesenchyme and start forming the islets of Langerhans. By the end of the gestation and close to birth, these islets contain immature beta cells with the capacity to express vascular endothelial growth factor and therefore to recruit ECs from the surrounding microenvironment. ECs in turn produce factors that are essential to maintain insulin secretion in pancreatic beta cells. Once assembled, a cross talk between endocrine cells and ECs maintain the integrity of islets toward an adequate function during the whole life of the adult individual. This review will focus in the EC role in the differentiation and maturation of pancreatic beta cells during embryogenesis as well as the current knowledge about the involvement of endothelium to derive pancreatic beta cells in vitro from mouse or human pluripotent stem cells.

关键词： Endothelium Endothelium-derived signals Differentiation Pancreas development Organogenesis

Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease

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Translational Neurodegeneration 2023年第1期12卷 801-823页

作者： Luis Enrique Arroyo-García Sara Bachiller Rocío Ruiz Antonio Boza-Serrano Antonio Rodríguez-Moreno Tomas Deierborg Yuniesky Andrade-talavera AndréFisahn Neuronal Oscillations Laboratory Division of NeurogeriatricsCenter for Alzheimer ResearchDepartment of NeurobiologyCare Sciences and SocietyKarolinska Institutet17164 SolnaSweden Experimental Neuroinflammation Laboratory Department of Experimental Medical ScienceLund UniversityBMC B1122184 LundSweden Clinical Unit of Infectious Diseases Microbiology and ParasitologyInstitute of Biomedicine of Seville(IBiS)Virgen del Rocío University HospitalCSICUniversity of SevilleSevilleSpain Department of Biochemistry and Molecular Biology University of SevilleCalle Profesor García González Nº241012 SevilleSpain Laboratory of Cellular Neuroscience and Plasticity Department of PhysiologyAnatomy and Cellular BiologyUniversidad Pablo de OlavideCarretera de Utrera Km-141013 SevilleSpain Department of Biosciences and Nutrition NeoKarolinska Institutet14183 HuddingeSweden

Background Alzheimer’s disease(AD)is a progressive multifaceted neurodegenerative disorder for which no disease-modifying treatment *** is central to the pathology progression,with evidence suggesting that microglia-released galectin-3(gal3)plays a pivotal role by amplifying neuroinflammation in ***,the possible involvement of gal3 in the disruption of neuronal network oscillations typical of AD remains *** Here,we investigated the functional implications of gal3 signaling on experimentally induced gamma oscillations ex vivo(20-80 Hz)by performing electrophysiological recordings in the hippocampal CA3 area of wild-type(WT)mice and of the 5×FAD mouse model of *** addition,the recorded slices from WT mice under acute gal3 application were analyzed with RT-qPCR to detect expression of some neuroinflammation-related genes,and amyloid-β(Aβ)plaque load was quantified by immunostaining in the CA3 area of 6-month-old 5×FAD mice with or without Gal3 knockout(KO).Results Gal3 application decreased gamma oscillation power and rhythmicity in an activity-dependent manner,which was accompanied by impairment of cellular dynamics in fast-spiking interneurons(FSNs)and pyramidal *** found that the gal3-induced disruption was mediated by the gal3 carbohydrate-recognition domain and prevented by the gal3 inhibitor TD139,which also prevented Aβ42-induced degradation of gamma ***-more,the 5×FAD mice lacking gal3(5×FAD-Gal3KO)exhibited WT-like gamma network dynamics and decreased Aβplaque *** We report for the first time that gal3 impairs neuronal network dynamics by spike-phase uncoupling of FSNs,inducing a network performance ***,our findings suggest gal3 inhibition as a potential therapeutic strategy to counteract the neuronal network instability typical of AD and other neurological disorders encompassing neuroinflammation and cognitive decline.

关键词： Galectin-3 Gamma oscillations Neuronal network dynamics Fast-spiking interneurons Alzheimer’s disease models Neuroinflammation TD139 Hippocampus

Detecting Anomalies in Irregular Data Using K-means Clustered Signal Dictionary

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Computer Technology and Application 2016年第5期7卷 244-252页

作者： G. talavera Reyes Rajan M. Chandra Ha Thu Le Zekeriya Aliyazicioglu Electrical and Computer Engineering Department California State Polytechnic University Pomona CA 91768 United States

The critical nature of satellite network traffic provides a challenging environment to detect intrusions. The intrusion detection method presented aims to raise an alert whenever satellite network signals begin to exhibit anomalous patterns determined by Euclidian distance metric. In line with anomaly-based intrusion detection systems, the method presented relies heavily on building a model of＂normal＂ through the creation of a signal dictionary using windowing and k-means clustering. The results of three signals fi＇om our case study are discussed to highlight the benefits and drawbacks of the method presented. Our preliminary results demonstrate that the clustering technique used has great potential for intrusion detection for non-periodic satellite network signals.

关键词： Intrusion detection irregular data K-means clustering machine learning signal dictionary