检索结果-南通市图书馆

An Analysis of the Accounting Costs Associated with 20-Month DR TB Regimens in Maputo City, Mozambique

Journal of Tuberculosis Research 2024年第2期12卷 73-90页

作者： Júlia Malache António Isaías Benzana Isabelle Munyangaju Benedita José Dulce osório Edy Nacarapa Claudia Mutaquiha Simeão Nhabinde Pereira Zindoga Universidade Catlica de Moambique Beira Moambique Centro de Estudos e Apoio Psicolgico (CEAP) Universidade Eduardo Mondlane Maputo Moambique ISGlobal Hospital Clnic Universitat de Barcelona Barcelona Spain Tinpswalo Association Vincentian Association to Fight AIDS and TB Chokwe Mozambique Programa Nacional de Controlo da Tuberculose Ministrio da Sade de Moambique Maputo Mozambique Faculdade de Economia Universidade Eduardo Mondlane Maputo Moambique

Introduction: Socioeconomic and demographic conditions in a country can influence tuberculosis incidence and mortality, with nearly 95% of tuberculosis-related deaths occurring in poorer countries. Mozambique is among the 30 countries with the highest TB burden. Objective: The study aimed to estimate the average direct medical cost of treating drug-resistant tuberculosis in 19 health centers in Maputo City, Mozambique. Methods: A retrospective analysis of direct medical costs was conducted on patients aged 18 and older who completed 20-month drug-resistant tuberculosis treatment regimens in Maputo City in 2019. Results: This analysis covered 140 patients who completed a 20-month treatment regimen, with 64.3% (78) being male and 35.7% (62) female. Approximately 50% of the participants were aged between 29 and 47. The average direct medical cost of DRTB treatment was $4789.43, reaching up to $6568.00, with a standard deviation of $753.26, including clinical interventions and treatment. Conclusion: The direct medical costs for a basic treatment package for a patient with drug-resistant TB in Mozambique equal 36 minimum wages. Developing alternative and innovative funding mechanisms and identifying ways to mitigate costs through the use of generic medicines would be beneficial.

关键词： Antitubercular Agents Multidrug-Resistant Healthcare Costs Tuberculosis Mozambique

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A rapid-assessment model on the potential of district energy:The case of Temuco in Chile

引用

Energy and Built Environment 2023年第3期4卷 328-340页

作者： Clara Camarasa Santiago Martinez Santaclara Trupti Yargattimath Pilar Lapuente Fuentes Carolina RiobóPezoa Juan Pablo berríos Celia Martinez Juez Zhuolun Chen UNEP-DTU Partnership CopenhagenDenmark United Nations Environment Program France Ministerio de Energía SantiagoChile Agencia de Sostenibilidad Energética SantiagoChile

District energy systems(DES)offer an optimal solution for decarbonising the heating and cooling sector while attaining multiple additional *** first step to analyse the potential of DES in both new and existing markets is through rapid assessments(RA).Currently,publicly available models lack rapid assessments of the technical-economic and environmental potential of *** RA model was developed within the framework of UNEP’s District Energy in Cities Initiative to identify DES’s potential spending low time and monetary *** this light,the study presents a model for conducting a rapid assessment applied to the case of Temuco,*** show that a total of 55 MW DH(district heating)capacity is required to cover the heating demand.A wood-chip boiler of 25 MW capacity and a gas boiler of 30 MW capacity are considered in the *** total CAPEX of the project is around 25 billion CLP,with a NPV of 10.5 billion CLP and an IRR of 14%.The project is also estimated to achieve an annual reduction of 24,382 tons of PM10 and 23,692 tons of *** model was validated against an independent study conducted by an international consulting company,and the results were found to be in close proximity with the ***,the model can be an effective tool for performing rapid assessments of DES projects in the region and subjecting attractive projects to more detailed pre-feasibility analysis.

关键词： District heating District energy system Rapid assessment Sustainable energy Chile

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rainfall Sensitivity to Microphysics and Planetary Boundary Layer Parameterizations in Convection-Permitting Simulations over Northwestern South America

引用

Journal of Meteorological Research 2024年第4期38卷 805-825页

作者： K.Santiago HERNANDEZ Sebastian GOMEZ-RIos Juan J.HENAO Vanessa ROBLEDO Alvaro RAMiREZ-CARDONA Angela M.RENDON Geolimna Escuela AmbientalFacultad de IngenieriaUniversidad de AntioquiaMedellin 050010Colombia Grupo de Ingenieria y Gestion Ambiental(GIGA) Escuela AmbientalFacultad de IngenieriaUniversidad de AntioquiaMedellin 050010Colombia Division of Atmospheric Sciences Desert Research InstituteRenoNV 89512USA

Convection-permitting modeling allows us to understand mechanisms that influence rainfall in specific ***,microphysics parameterization(MP) and planetary boundary layer(PBL) schemes remain an important source of uncertainty,affecting rainfall intensity,occurrence,duration,and ***,we study the sensitivity of rainfall to three MP [Weather Research and Forecasting(WRF) Single-Moment 6-class(WSM6),Thompson,and Morrison] and two PBL [the Yonsei University(YSU) and Mellor–Yamada Nakanishi Niino(MYNN)] schemes with a convection-permitting resolution(4 km) over northwestern South America(NWSA).Simulations were performed by using the WRF model and the results were evaluated against soundings,rain gauges,and satellite data,considering the spatio-temporal variability of rainfall over diverse regions prone to deep convection in *** and PBL schemes largely influenced simulated rainfall,with better results for the less computationally expensive WSM6 MP and YSU PBL *** rain gauges and satellite estimates,simulations with Morrison MP overestimated rainfall,especially westward of the Andes,whereas the MYNN PBL underestimated precipitation in the Amazon–Savannas *** found that the uncertainty in the rainfall representation is highly dependent on the region,with a higher influence of MP in the Colombian Pacific and PBL in the Amazon–Savannas *** analyzing rainfall-related processes,the selection of both MP and PBL parameterizations exerted a large influence on the simulated lower tropospheric moisture flux and moisture *** schemes significantly influenced the downward shortwave radiation,with MYNN simulating a greater amount of low clouds,which decreased the radiation ***,latent heat fluxes were greater for YSU,favoring moist convection and *** schemes had a marked impact on vertical ***,Morrison MP showed stronger convection and higher precipitation rates,which is assoc

关键词： sensitivity microphysics planetary boundary layer(PBL) Weather Research and Forecasting(WRF) processes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Role of PIN Auxin Efflux Carriers in Polar Auxin Transport and Accumulation and Their Effect on Shaping Maize Development

引用

Molecular Plant 2012年第4期5卷 787-798页

作者： cristian Forestan Serena Varotto Department of Environmental Agronomy and Crop Science--University of Padova Viale dell'Universita 16 35020 Legnaro (PD) Italy

In plants, proper seed development and the continuing post-embryonic organogenesis both require that dif- ferent cell types are correctly differentiated in response to internal and external stimuli. Among internal stimuli, plant hormones and particularly auxin and its polar transport （PAT） have been shown to regulate a multitude of plant phys- iological processes during vegetative and reproductive development. Although our current auxin knowledge is almost based on the results from researches on the eudicot Arabidopsis thaliana, during the last few years, many studies tried to transfer this knowledge from model to crop species, maize in particular. Applications of auxin transport inhibitors, mutant characterization, and molecular and cell biology approaches, facilitated by the sequencing of the maize genome, allowed the identification of genes involved in auxin metabolism, signaling, and particularly in polar auxin transport. PIN auxin efflux carriers have been shown to play an essential role in regulating PAT during both seed and post-embryonic development in maize. In this review, we provide a summary of the recent findings on PIN-mediated polar auxin transport during maize development. Similarities and differences between maize and Arabidopsis are analyzed and discussed, also considering that their different plant architecture depends on the differentiation of structures whose development is con- trolled by auxins.

关键词： auxin PIN-formed auxin efflux carrier PAT Polar Auxin Transport kernel development meristem organ-ogenesis Zea mays.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Degenerate Nonlinear Elliptic Equations Lacking in Compactness

引用

Chinese Annals of Mathematics,Series B 2016年第1期37卷 53-72页

作者： Maria MALIN cristian UDREA Department of Mathematics University of Craiova

In this paper, the authors prove the existence of solutions for degenerate elliptic equations of the form-div(a(x)▽_p u(x)) = g(λ, x, |u|^(p-2)u) in R^N, where ▽_pu =|▽u|^(p-2)▽u and a(x) is a degenerate nonnegative weight. The authors also investigate a related nonlinear eigenvalue problem obtaining an existence result which contains information about the location and multiplicity of eigensolutions. The proofs of the main results are obtained by using the critical point theory in Sobolev weighted spaces combined with a Caffarelli-Kohn-Nirenberg-type inequality and by using a specific minimax method, but without making use of the Palais-Smale condition.

关键词： Degenerate equations p-Laplacian Sobolev weighted spaces Mountain-pass theorem

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dynamic Analysis for the Global Performance of An SPM-Feeder-Cage System Under Waves and Currents

引用

China Ocean Engineering 2015年第3期29卷 415-430页

作者： cristian CIFUENTES M.H.KIM Ocean Engineering Program Department of Civil Engineering Texas A&M University College Station

In the present study, the dynamic response of a coupled SPM-feeder-cage system under irregular waves and shear currents is analyzed. A numerical model is developed by using the commercial software Orca Flex. Hydrodynamics coefficients of the vessel are calculated by using a 3D diffraction/radiation panel program. First- and second-order wave forces are included in the calculations. Morison equation is used to compute the drag force on line elements representing the net. Drag coefficients are determined at every time step in the simulation considering the relative normal velocity between the structural elements and the fluid flow. The dynamic response of the coupled system is analyzed for various environments and net materials. The results of the study show the effects of solidity ratio of the net and vertical positions of the cage on the overall dynamic response of the system, confirming the viability of this type of configuration for future development of offshore aquaculture in deep waters.

关键词： offshore aquaculture SPM(single point mooring) feeder vessel connecting lines operational/survival environment drag force equivalent net cage grouping net modeling line tensions solidity ratio

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

In-situ nonvolatile and volatile modulation for optical neural networks

引用

Advanced Photonics 2023年第5期5卷 1-2页

作者： Carlos A.Ríos Ocampo University of Maryland Department of Materials Science&EngineeringCollege ParkMarylandUnited States University of Maryland Institute for Research in Electronics and Applied PhysicsCollege ParkMarylandUnited States

High-performance integrated optical memristors are crucial in developing optical neural networks based on in-memory *** devices are building blocks capable of modulating the transmission of a propagating mode in a multilevel and nonvolatile fashion,thus allowing storage and multiplication of analog signals in the same device.1 Chalcogenide phase change materials(PCMs)are candidates for high-performance devices.

关键词： optical networks neural

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Light at night and lung cancer risk:A worldwide interdisciplinary and time-series study

引用

Chinese Medical Journal Pulmonary and Critical Care Medicine 2024年第1期2卷 56-62页

作者： Runchen Wang Qixia Wang Jianfu Li Jianrong Zhang Shixuan Lyu Wenhao Chi Zhiming Ye Xuanzhuang Lu Ying Shi Yubin Wang Xinjian Wu Ruiyu Hu Mónica Pérez-Ríos Jianxing He Wenhua Liang Department of Thoracic Surgery and Oncology The First Affiliated Hospital of Guangzhou Medical UniversityState Key Laboratory of Respiratory DiseaseNational Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory HealthGuangzhouGuangdong 510120China Department of Respiratory Disease China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory DiseaseThe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong 510120China Centre for Cancer Research&Department of General Practice Faculty of MedicineDentistry and Health SciencesUniversity of MelbourneVictorian Comprehensive Cancer CentreMelbourneVictoria 3010Australia Department of Civil Engineering University of BristolBristolBS81TRUK Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Nanshan School Guangzhou Medical UniversityGuangzhouGuangdong 511436China State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing Wuhan UniversityWuhanHubei 430079China GNSS Research Center Wuhan UniversityWuhanHubei 430079China First Clinical School Guangzhou Medical UniversityGuangzhouGuangdong 511436China Preventive Medicine and Public Health Department University of Santiago de CompostelaCIBER de Epidemiología y Salud Pública(CIBERESP)Health Research Institute of Santiago de Compostela(IDIS)Santiago de CompostelaGalicia 15782Spain Southern Medical University GuangzhouGuangdong 510515China

Background:Light at night(LAN)has become a concern in interdisciplinary research in recent *** global interdisciplinary study aimed to explore the exposure-lag-response association between LAN exposure and lung cancer ***:LAN data were obtained from the Defense Meteorological Satellite Program’s Operational Linescan *** of lung cancer incidence,socio-demographic index,and smoking prevalence of populations in 201 countries/territories from 1992 to 2018 were collected from the Global Burden of Disease *** correlation tests and population-weighted linear regression analysis were used to evaluate the correlation between LAN exposure and lung cancer incidence.A distributed lag nonlinear model(DLNM)was used to assess the exposure-lag effects of LAN exposure on lung cancer ***:The Spearman correlation coefficients were 0.286-0.355 and the population-weighted linear regression correlation coefficients were *** adjustment for socio-demographic index and smoking preva-lence,the Spearman correlation coefficients were 0.264-0.357 and the population-weighted linear regression correlation coefficients were *** the DLNM,the maximum relative risk was 1.04(1.02-1.06)at LAN exposure of 8.6 with a 2.6-year lag *** adjustment for socio-demographic index and smoking prevalence,the maximum relative risk was 1.05(1.02-1.07)at LAN exposure of 8.6 with a 2.4-year lag ***:High LAN exposure was associated with increased lung cancer incidence,and this effect had a specific lag *** with traditional individual-level studies,this group-level study provides a novel paradigm of effective,efficient,and scalable screening for risk factors.

关键词： Light at night Satellite imagery Lung cancer Distributed lag nonlinear model(DLNM) Melatonin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A high Q terahertz metamaterial absorber using concentric elliptical ring resonators for harmful gas sensing applications

引用

Defence Technology（防务技术） 2023年第4期22卷 69-73页

作者： Bhargav Appasani Avireni Srinivasulu cristian Ravariu Department of Electronics Engineering Kalinga Institute of Industrial TechnologyBhubaneswarIndia Department of Electronics Engineering K R Mangalam UniversityGurgaonIndia Department of Electronic Devices Circuits and ArchitecturesPolytechnic University of BucharestBucharestRomania

A nearly perfect metamaterial absorber is proposed that can find utility in terahertz sensing *** design consists of two concentric elliptical ring resonators(ERRs)whose parameters are appropriately set to achieve dual band absorption with near perfect *** first absorption band at 3.62 THz having a Q-factor of 51.7 was caused due to the currents in the outer and inner *** second absorption peak at 3.814 THz having a Q factor of 1411.11 was a consequence of currents flowing across the gap between the two concentric ***,it is observed that the absorption bands are sensitive to the variation in refractive index of the surrounding *** sensitivity's in the absorption bands are 3 THz/RIU and 3.59 THz/RIU respectively.A sensor is proposed based on this design to detect harmful gases,which is demonstrated for detection of Methane and *** Q-factor and high sensitivity of the narrow band makes the design an excellent sensor for detecting variations in the refractive index.

关键词： Refractive index Plasma frequency Metamaterials Terahertz absorption Q-factor Gas sensing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Redox regulation of mammalian sperm capacitation

引用

Asian Journal of Andrology 2015年第4期17卷 583-590页

作者： cristian O'Flaherty Urology Research Laboratory Surgery Department (Urology Division) Faculty of Medicine McGill University Montreal Quebec Canada The Research Institute McGillUniversity Health Centre Montreal Quebec Canada.

Capacitation is a series of morphological and metabolic changes necessary for the spermatozoon to achieve fertilizing ability. One of the earlier happenings during mammalian sperm capacitation is the production of reactive oxygen species （Ros） that will trigger and regulate a series of events including protein phosphorylation, in a time-dependent fashion. The identity of the sperm oxidase responsible for the production of Ros involved in capacitation is still elusive, and several candidates are discussed in this review. Interestingly, Ros-induced Ros formation has been described during human sperm capacitation. Redox signaling during capacitation is associated with changes in thiol groups of proteins located on the plasma membrane and subcellular compartments of the spermatozoon. Both, oxidation of thiols forming disulfide bridges and the increase on thiol content are necessary to regulate different sperm proteins associated with capacitation. Reducing equivalents such as NADH and NADPH are necessary to support capacitation in many species including humans. Lactate dehydrogenase, glucose-6-phospohate dehydrogenase, and isocitrate dehydrogenase are responsible in supplying NAD （P） H for sperm capacitation. Peroxiredoxins （PRDXs） are newly described enzymes with antioxidant properties that can protect mammalian spermatozoa; however, they are also candidates for assuring the regulation of redox signaling required for sperm capacitation. The dysregulation of PRDXs and of enzymes needed for their reactivation such as thioredoxin/thioredoxin reductase system and glutathione-S-transferases impairs sperm motility, capacitation, and promotes DNA damage in spermatozoa leading to male infertility.

关键词： dehydrogenases oxidases peroxiredoxins reactive oxygen species spermatozoa thiols thioredoxins

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：